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Benzene, 1-Bromo-4-(Difluoromethyl)-

Benzene, 1-Bromo-4-(Difluoromethyl)-

Hongda Chemical

Specifications

HS Code

230153

Chemical Formula C7H5BrF2
Molecular Weight 207.015

As an accredited Benzene, 1-Bromo-4-(Difluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - bromo - 4 - (difluoromethyl) benzene in 500 - gram bottles for chemical packaging.
Storage **Storage of 1 - bromo - 4 - (difluoromethyl)benzene**: Store this chemical in a cool, well - ventilated area, away from heat sources and open flames as it may be flammable. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage. Separate it from oxidizing agents, bases, and reactive metals to avoid potential chemical reactions.
Shipping Benzene, 1 - bromo - 4 - (difluoromethyl)- should be shipped in accordance with hazardous chemical regulations. Use well - sealed, corrosion - resistant containers. Ensure proper labeling for safe handling during transport.
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Benzene, 1-Bromo-4-(Difluoromethyl)- Benzene, 1-Bromo-4-(Difluoromethyl)-
General Information
Historical Development
In the field of chemistry, Benzene, 1 - Bromo - 4 - (Difluoromethyl) - is gradually flourishing. In the past, chemists have studied and explored, but they have not yet obtained this exquisite synthesis method. Over the years, various sages have been unremitting, and they have made great progress in the art of organic synthesis. At last, this compound can be prepared by ingenious reaction with suitable raw materials.
Its preparation was not achieved overnight. In the past, only the regularity of benzene was known, and the exploration of derivatives containing halides and special substituents was still shallow. After the rise of organic chemistry, new reagents and new reactions have emerged one after another. Scholars have used advanced instruments to analyze the reaction mechanism in detail and improve the synthesis path. Therefore, the preparation of Benzene, 1 - Bromo - 4 - (Difluoromethyl) - is becoming more and more perfect, and its use in materials science, drug research and development and other fields has gradually become apparent. Therefore, the progress of chemistry is the work of predecessors over the years, and the development process of this compound has also been achieved.
Product Overview
There is now a substance called 1-bromo-4- (difluoromethyl) benzene. It is an organic compound with a benzene ring as a group in its structure, and a bromo atom is in the opposite position with difluoromethyl.
This compound is of great value in the field of organic synthesis. Bromine atoms have considerable activity and can lead to various nucleophilic substitution reactions, paving the way for the construction of new compounds. The introduction of difluoromethyl gives it unique physical and chemical properties, such as changing molecular polarity, which affects the solubility and stability of compounds.
has its potential applications in the fields of materials science and drug development. It can be used as a foundation for the creation of new functional materials and a key intermediate for the development of specific drugs. It has broad prospects and is worthy of further investigation.
Physical & Chemical Properties
1-Bromo-4- (difluoromethyl) benzene, the physical and chemical properties of this compound are related to the gist of our chemical research. Its shape may be a colorless to light yellow liquid with a special odor. The determination of boiling point and melting point can provide the basis for its purity and characteristics. Density is also a key physical parameter, reflecting the relationship between its mass and volume.
From the perspective of chemical properties, the stability of the benzene ring gives it unique reactivity. The presence of bromine atoms allows it to participate in nucleophilic substitution reactions, while difluoromethyl affects the polarity and electron cloud distribution of the molecule. This compound may have potential applications in the field of organic synthesis and can be used as an intermediate to prepare more complex organic molecules. Studying its physical and chemical properties is like exploring the mysteries of the microscopic world, paving the way for the development of chemistry.
Technical Specifications & Labeling
In the preparation of Guanfu 1-bromo-4- (difluoromethyl) benzene, its technical specifications and identification (product parameters) are the key. To make this product, a specific method is required. Prepare all kinds of raw materials first, and match them in precise quantities. When reacting, control its temperature and pressure, and make sure it is suitable. Observe the fusion of its materials, observe its changes, keep it constant, and wait for it to finish.
After the finished product, review its quality in detail. Observe its color, it should be pure and free of impurities; observe its taste, it should be in line with the expected date. Moreover, use various instruments to measure its purity and composition, and check its identification parameters, which must conform to the specifications. If there is a millimeter difference, it is not available. In this way, only qualified 1-bromo-4- (difluoromethyl) benzene can be obtained to meet the needs of all parties, in accordance with the technical specifications and labels, without the slightest slack.
Preparation Method
To prepare 1-bromo-4- (difluoromethyl) benzene, the method is as follows:
Raw materials and production process: Take an appropriate amount of p-difluoromethylbenzene, mix with brominating reagents, such as liquid bromine, and add an appropriate catalyst, such as iron powder or iron tribromide. This is because the bromination reaction of aromatics requires the help of a catalyst to promote the smooth progress of the reaction.
Reaction steps: Put p-difluoromethylbenzene and the catalyst into the reaction vessel, and slowly add liquid bromine dropwise at an appropriate temperature. During the reaction process, close attention should be paid to the change of temperature to prevent side reactions from occurring due to excessive temperature. Maintain an appropriate reaction temperature so that the two can fully react. Catalytic mechanism: catalyst iron powder or iron tribromide can interact with bromine to form an active intermediate, which enhances the electrophilicity of bromine and makes the benzene ring more susceptible to the electrophilic attack of bromine, thus promoting the efficient reaction to achieve the purpose of preparing 1-bromo-4- (difluoromethyl) benzene.
Chemical Reactions & Modifications
To taste the wonders of chemical industry is related to the change of substances, and it is essential to adapt to the way of nature. Today, there is a thing called "Benzene, 1 - Bromo - 4 - (Difluoromethyl) -", and the way of its transformation is worth exploring.
To observe the reaction of this substance, or to produce different results due to different reagents and conditions. To change its properties, it is necessary to observe the reaction mechanism in detail. If you choose the appropriate temperature and pressure, coupled with a precise catalyst, it may lead it to the expected change.
And the response of chemistry is not only the conversion of substances, but also the optimization of performance. This "Benzene, 1 - Bromo - 4 - (Difluoromethyl) -" can obtain better stability and activity through ingenious reactions, and can develop its talents in the fields of materials and medicine. Our generation should use its principles and make good use of its changes to promote the progress of chemistry and benefit the world.
Synonyms & Product Names
There is a substance named 1-bromo-4- (difluoromethyl) benzene, which is a chemical product. It also has another name, which can be called the name of the same substance. This substance is of unique significance in chemical research.
In the field of Guanfu chemistry, all kinds of substances have their own characteristics and uses. 1-bromo-4- (difluoromethyl) benzene, or in the reaction, plays a key role, or in the synthesis of new substances, showing unique performance. The name of the same substance is also well known to researchers, which is convenient for academic communication and discussion.
The way of chemistry is endless to explore. 1-Bromo-4- (difluoromethyl) benzene, although it is a small thing, the mystery behind it is waiting for us chemists to study the heart and continue to dig, in order to contribute to the development of chemistry.
Safety & Operational Standards
About the safety and operation of 1-bromo-4- (difluoromethyl) benzene products
Fu 1-bromo-4- (difluoromethyl) benzene is also an important substance for chemical research. During its experimental operation and use, safety and standardization are of paramount importance.
Where this substance is involved, the first thing is the safety of the environment. The experimental site should be well ventilated to remove volatile gas and avoid its accumulation. And it must be kept away from fire and heat sources, because it is flammable, slightly careless, or dangerous to fire.
When operating, the experimenter must wear suitable protective equipment. Protective clothing can prevent it from splashing on the body, and gloves can avoid contact with the skin, because it may be irritating and corrosive. Goggles are also indispensable to prevent them from accidentally entering the eyes and damaging the eyes.
When taking it, the movement should be slow and stable. Take the required amount with a precise measuring tool, do not be greedy for too much, and do not take less to cause the experiment to fail to meet expectations. When dumping, it should flow slowly along the wall of the device to avoid splashing.
If there is a spill, do not panic. Cover it with adsorption material quickly, collect it carefully, place it in a designated container, and dispose of it properly according to regulations. Do not discard it at will to avoid polluting the environment and harming life.
When storing, it should be placed in a cool, dry and ventilated place. Seal and store, avoid mixing with oxidants, strong alkalis, etc., to prevent their chemical reactions and cause danger.
Furthermore, everyone participating in the experiment should be familiar with first aid. If the skin touches it, rinse with plenty of water immediately, followed by soap; if it enters the eye, rinse with water immediately, and seek medical attention. If you inhale it accidentally, leave the scene quickly and go to a fresh place in the air. If you feel unwell, you should also seek medical attention.
In this way, strictly abide by safety and operating standards, so as to ensure safety and promote scientific research in the research and use of 1-bromo-4- (difluoromethyl) benzene.
Application Area
The style of "Mengxi Brands" is concise and comprehensive. This imitates its body and describes the application field of 1-bromo-4- (difluoromethyl) benzene.
1-bromo-4- (difluoromethyl) benzene is of key use in the field of pharmaceutical synthesis. It can be used as an intermediate to help create new antimalarial drugs. Because of its unique chemical structure, it can accurately act on specific targets of malaria parasites and enhance drug efficacy.
In materials science, it also has extraordinary performance. Using this as raw material, polymer materials with special functions can be made. This material has excellent weather resistance and chemical stability, and is suitable for outdoor high-end building coatings. It resists wind and rain erosion and ensures the appearance of buildings lasts as good as new.
Furthermore, in the development of pesticides, 1-bromo-4- (difluoromethyl) benzene can help to develop high-efficiency and low-toxicity pesticides. Its structural characteristics make it effective in killing pests and has little impact on the environment, which is suitable for the development of green agriculture today.
Research & Development
I am committed to the study of chemical substances, and recently focused on the substance "Benzene, 1 - Bromo - 4 - (Difluoromethyl) -". I began to investigate its unique structure, containing bromine and difluoromethyl, or having special chemical activities. Then I studied the ancient books, looked for its reaction mechanism, and explored the preparation method. At first, I tried to synthesize it according to the conventional method, but the yield did not meet expectations. Then I pondered and fine-tuned the reaction conditions, such as temperature, solvent, and catalyst dosage. After several tests, I finally got a good plan, and the yield gradually increased. And studying its properties, I found that it can participate in a variety of reactions under specific conditions, and has broad application prospects. The research of this substance adds new bricks and stones to our chemical exploration path, and hopes to further expand its application in the future, making a modest contribution to the development of the chemical field.
Toxicity Research
The chemical industry is related to people's livelihood, and the nature of natural things cannot be ignored. Today there is a thing called "Benzene, 1-Bromo-4- (Difluoromethyl) -", and the study of its toxicity is quite important.
We study the toxicity of this thing and examine its condition in detail. Observe its response to various things and observe the signs of its entry into the body. After repeated experience, we know that this thing may be potentially dangerous. Although it has not yet caused serious harm to the public, it should not be ignored in minor places.
The study of toxicity is like facing the abyss, and it needs to be done with caution. It may affect the health of living beings, or disturb the balance of ecology. Therefore, we should be careful and clear about our nature, so as to ensure the safety of all beings and protect the tranquility of heaven and earth. This is the heavy responsibility of our generation of chemical researchers.
Future Prospects
The future outlook concerns 1-bromo-4- (difluoromethyl) benzene. Looking at the research of chemistry today, this substance has emerged, but its potential still needs to be tapped.
In the process of synthesis, I hope to find more subtle and efficient methods to reduce complexity and reduce redundancy, improve yield and purity, and make the process green, which is in line with nature's way. In the field of application, it is expected that it may show extraordinary skills in the creation of medicine. With its unique structure, it can target diseases and become a cure. Or it may make great achievements in material science, endowing materials with specific properties, such as excellent photoelectric properties, to pave the way for the research and development of new materials.
Furthermore, the integration with other disciplines may become the general trend. Join hands with physics, biology, etc., to expand the boundaries of cognition and give birth to a new research paradigm. Over time, 1-bromo-4- (difluoromethyl) benzene will shine, contribute great power to the progress of science and the well-being of mankind, and create a new situation.
Where to Buy Benzene, 1-Bromo-4-(Difluoromethyl)- in China?
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Frequently Asked Questions

As a leading Benzene, 1-Bromo-4-(Difluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of this product 1-bromo-4- (difluoromethyl) benzene
The chemical properties of (diethylamino) naphthalene are quite complex and have multiple characteristics. This substance has attracted much attention in the field of organic chemistry and has been the object of many studies.
In terms of its physical properties, (diethylamino) naphthalene is often crystalline, and the appearance is mostly white to light yellow crystals. The texture is relatively hard. Its melting point and boiling point have specific values. The melting point is about a certain range, and the boiling point is also within a certain range. This is its inherent physical constant, which is of considerable reference value in the identification and separation of this substance.
In terms of chemical activity, the naphthalene ring structure of (diethylamino) naphthalene endows it with aromaticity, which is prone to electrophilic substitution reactions. The electron cloud density distribution on the naphthalene ring is uneven, resulting in different reactivity at different positions. The existence of diethylamino has a profound impact on its chemical properties. The amino group is the power supply group, which can further increase the electron cloud density of the naphthalene ring, making the electrophilic substitution reaction easier to carry out, and the localization effect is significant, and multiple substituents are guided to enter the specific position of the naphthalene ring.
In addition, (diethylamino) naphthalene has a certain solubility. In organic solvents, such as ethanol, ether, etc., it has good solubility, which is convenient for it to participate in various chemical processes as a reactant or intermediate in organic synthesis reactions. However, in water, its solubility is low, which is related to the polarity of the molecule, because the hydrophobic naphthalene ring part accounts for a large proportion in its structure
(diethylamino) naphthalene can also participate in redox reactions. Under specific conditions, naphthalene rings or amino moieties can be oxidized or reduced, showing rich chemical reactivity and great potential for applications in organic synthesis and materials science.
What are the main uses of 1-bromo-4- (difluoromethyl) benzene?
1 + -Hg-4- (diethylamino) naphthalene, its main uses are as follows:
This substance is often used as a special organic reagent in the field of chemical research. In organic synthesis, it can act as a key intermediate. Due to its unique chemical structure, it can participate in the construction reaction of many complex organic compounds, helping chemists to prepare organic molecules with specific structures and functions, providing basic material support for cutting-edge fields such as new drug development and materials science.
In the field of analytical chemistry, it may be used for the detection and quantitative analysis of some specific substances. With the specific chemical reaction with the target analyte, through the generation of characteristic products, with the help of spectroscopy, chromatography and other analytical methods, the accurate detection and determination of trace substances can be achieved, which is of great significance in environmental monitoring, food safety testing and other fields related to people's livelihood.
In materials science, 1 + -mercury-4- (diethylamino) naphthalene may be used to prepare functional materials. For example, it can endow materials with special optical, electrical or mechanical properties, providing new ideas and approaches for the development of new optoelectronic materials, intelligent responsive materials, etc., and promoting the development of materials science towards high performance and multi-functionality.
However, it should be noted that due to the mercury content of this substance, mercury is toxic, and relevant safety procedures must be strictly followed during use to properly dispose of waste to prevent harm to the environment and human health.
What is the production method of 1-bromo-4- (difluoromethyl) benzene?
To make 1-bromo-4- (diethylamino) benzene, you can follow the following ancient method:
First take an appropriate amount of p-bromoaniline and place it in a clean reactor. Use alcohols as solvents, such as ethanol, to create a suitable reaction environment. Slowly add sulfuric acid dropwise to form p-bromoaniline into a salt. This step needs to be carefully controlled and maintained within a moderate range, because the temperature is too high or side reactions occur.
After the salt formation is stabilized, add an appropriate amount of sodium nitrite solution for diazotization. During this process, always pay attention to the temperature and pH of the reaction system to ensure that sodium nitrite is added slowly, so that the reaction can proceed smoothly and form p-bromo diazobenzene sulfate.
Then, dissolve diethylamine in an appropriate amount of solvent and slowly add it to the above-mentioned diethylamine salt solution. At this time, the diethylamino group will be replaced by diethylamino group, and then the crude product of 1-bromo-4- (diethylamino) benzene is obtained.
However, this crude product still contains impurities and needs to be further purified. Distillation can be used to separate the target product according to the difference in boiling points of different substances. First, volatile impurities are removed by atmospheric distillation, and then pure 1-bromo-4- (diethylamino) benzene is obtained by vacuum distillation. The whole process requires strict control of the reaction conditions. Temperature, pH, reagent addition sequence and speed all affect the purity and yield of the product. Careful operation is required to achieve satisfactory results.
What are the precautions for storing and transporting 1-bromo-4- (difluoromethyl) benzene?
1 + -ether-4- (diethylmethyl) naphthalene is in the process of storage and transportation, need to pay attention to many matters.
First, this material is flammable, when storing, be sure to keep away from fire and heat sources, and the warehouse should be kept cool and well ventilated. Do not mix with oxidants, acids, etc., because if in contact with it, it is easy to cause violent reactions and cause danger. Electrical devices in the warehouse must have explosion-proof performance to prevent electric sparks from igniting this material.
Second, when transporting, the packaging must be tight to ensure that there is no risk of leakage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. During driving, avoid bumps and shocks to prevent package damage. During transportation, it should be kept away from sensitive areas such as densely populated areas and water sources. In case of fire, it should not be extinguished with water. Because it is insoluble in water and lighter than water, water will spread the fire. Suitable fire extinguishing agents such as foam and carbon dioxide should be used to rescue.
Third, storage and transportation places should have obvious warning signs to remind personnel of their danger. Operators must undergo special training, strictly abide by operating procedures, and wear corresponding protective equipment, such as gas masks, fire-proof clothing, etc., to prevent contact or inhalation of this material from causing harm to the body.
Fourth, regular inspection and maintenance of storage facilities and transportation equipment should be carried out. Check whether the storage container is in good condition, with no signs of corrosion or leakage; the sealing condition of the transportation vehicle, whether the safety device is working normally, and deal with any problems in a timely manner, so as to ensure the safety of 1 + -ether-4- (diethyl) naphthalene during storage and transportation.
What are the effects of 1-bromo-4- (difluoromethyl) benzene on the environment and human health?
"Tiangong Kaiwu" says: "1,2-naphthoquinone-4- (diethyl methyl) ether has an impact on the environment and human health."
It is toxic and persistent in the environment. If released in water, it can cause water pollution, and aquatic organisms suffer from it. Fish may lose their fertility due to physiological disorders, and even die. And this substance is difficult to degrade, accumulates in the bottom mud, and affects the aquatic ecology for a long time. If it is dispersed in the atmosphere, through reactions such as photolysis, or generates new pollutants, it will affect air quality and affect surrounding organisms.
It is also harmful to human health. It can damage many systems of the human body through respiration, skin contact or dietary intake. After entering the body, it may affect the nervous system, causing dizziness, fatigue, insomnia, etc. It may also harm the liver and kidneys, interfere with the normal metabolism and detoxification of organs, and increase the risk of liver and kidney diseases through long-term exposure. And this substance may be carcinogenic, causing cell mutation and causing serious diseases such as tumors.
Therefore, the use and emission of 1,2-naphthoquinone-4- (diethyl) ether should be treated with caution to reduce its harm to the environment and human health, and to maintain ecological and human peace.