What is the main use of this product 1-bromo-4-chloro-2 - (trifluoromethyl) benzene
This medicine has the ability to relieve all kinds of poisons and eliminate epidemics, and is mostly used by doctors to treat diseases and save people. It has a warm nature, a refreshing taste, and is attributed to the lungs and spleen.
In medical practice, it is often used to exorcise evil spirits and remove filth. When the plague qi is rampant, it can be burned and smoked to purify the indoor filth, making it difficult for the plague to invade. The ancients said: "If the evil qi is prosperous, the disease will be sick, and the righteous qi will be stored in it, and the evil will not be dried." This medicine uses its warm nature to help the righteous qi to control external evil spirits and eliminate the filth and evil plague qi.
It can also be used to treat sores, swelling and poison. Where sores start, they are red, swollen, Because the medicine can pass through qi and blood, the poison and evil of stagnation can be dissipated, just like breaking the siege of a soldier. If the evil is gone, the swelling and pain will be relieved.
It is also effective in the syndrome of cold-dampness qi stagnation. If the spleen and stomach are invaded by cold-dampness, causing qi blockage, abdominal distension and pain, vomiting and diarrhea, etc., this medicine can warm the spleen and stomach, use qi to relieve pain, and relieve dampness and diarrhea.
In addition, it is also often used in the disease of itchy skin. Or washing with decoction, or applying it at the end of the study, it can remove wind and relieve itching, and relieve skin discomfort.
However, the way of medication lies in accurate syndrome differentiation and appropriate dosage. Use it properly, like a drum should be used; if it is misused, it is afraid of other changes. Doctors should carefully review the condition and consider the medication, so that the medicine can exert its maximum effect and save people from pain.
What are the physical properties of 1-bromo-4-chloro-2- (trifluoromethyl) benzene
The physical properties of 1 + -mercury-4 + -arsenic-2 + - (triethylmethyl) benzene are as follows:
Mercury is a liquid metal at room temperature, silver-white and metallic luster, with a high weight and density, about 13.59 g/cm3. Its melting point is very low, -38.87 ° C, and its boiling point is relatively low, at 356.6 ° C. Mercury has excellent fluidity and good electrical conductivity. However, mercury is highly toxic and volatile, and can form mercury vapor in the air. Inhalation by the human body can harm the nervous, digestive and immune systems.
Arsenic, there are three allotropes of gray, yellow, and black-brown. It is commonly known as gray arsenic, a brittle crystal with metallic luster. The density is about 5.73 g/cm3, the melting point is 817 ° C (at 28 atmospheres), and sublimation is at 613 ° C. Arsenic is stable in dry air, and oxides gradually form on the surface in humid air. Arsenic and its compounds are toxic, and excessive intake can cause serious health problems.
(triethylmethyl) benzene, a colorless liquid at room temperature and pressure, has an aromatic odor. Its density is less than that of water, and it is difficult to dissolve in water. It can be miscible with most organic solvents. The boiling point is about 170-180 ° C, and the specific position of the substituent varies slightly. ( Triethylmethyl) benzene is flammable. In case of open flame and high heat energy, it can cause combustion and explosion, and its vapor and air can form explosive mixtures.
These substances may be toxic, flammable, and volatile. When using and storing, pay extra attention to ensure safety.
What are the chemical properties of 1-bromo-4-chloro-2 - (trifluoromethyl) benzene?
The chemical properties of 1 + -hydroxyl-4-alkane-2- (triethylmethyl) ether are particularly important. Looking at this compound, hydroxyl is active, often reacts with other substances, and can form hydrogen bonds, which is the key starting point in many reaction pathways. The 4-alkane part, because of its carbon chain structure, endows this compound with specific hydrophobicity, which affects its solubility and miscibility in different media. Furthermore, the group of 2 - (triethylmethyl) ether, with its unique steric resistance and electronic effects, affects the reactivity and selectivity of this compound.
Hydroxyl is easily neutralized with acids, or under appropriate conditions, reacts with halogenated hydrocarbons to form new ethers. Although the carbon chain of 4-alkane is relatively stable, it can also be oxidized by strong oxidizing agents, resulting in the break of the carbon chain or the addition of functional groups. As for the part of 2 - (triethyl) ether, due to its steric hindrance, it can often protect the group of the neighboring site and make the reaction tend to a specific direction.
In the field of organic synthesis, 1 + -hydroxyl-4-alkane-2 - (triethyl) ether is often an important intermediate. With its active hydroxyl and unique structure, it can build complex organic molecular structures through various reactions. In pharmaceutical chemistry, or due to its own chemical properties, it exhibits specific biological activities and is an important basis for the development of new drugs. Its solubility, reactivity and other chemical properties have considerable application potential in materials science, fine chemistry and many other fields, and can be a key raw material for the synthesis of materials with special properties.
What are the preparation methods of 1-bromo-4-chloro-2 - (trifluoromethyl) benzene?
To prepare 1-bromo-4-iodine-2- (trimethyl) benzene, the following ancient methods can be followed:
First, start with benzene and brominate it first. Take an appropriate amount of benzene, put it in a flask, add iron powder as catalyst, and slowly add liquid bromine dropwise. Because the bromination of benzene is an electrophilic substitution, bromine atoms are catalyzed by iron, and the benzene ring is preferred to obtain bromobenzene. This step requires temperature control, do not overreact.
Then, iodine bromobenzene. Take iodine and bromobenzene as materials, add an appropriate amount of oxidant, such as a mixture of concentrated sulfuric acid and potassium iodate. Under the action of an oxidizing agent, iodine forms an electrophilic reagent and attacks the bromobenzene ring to obtain 1-bromo-4-iodobenzene. In this case, because bromine is an ortho-para-locator, iodine enters the anti-position of bromine.
Finally, alkylation is performed. Using 1-bromo-4-iodobenzene and halogenated alkanes (such as chlorotrimethylmethane) as raw materials, anhydrous aluminum trichloride is used as a catalyst and reacts in a suitable solvent (such as carbon disulfide). Aluminum trichloride interacts with halogenated alkanes to generate carbon cations and attack the benzene ring to obtain 1-bromo-4-iodine-2
Second, iodobenzene can also be substituted first. Benzene and iodine are catalyzed by a specific catalytic system (such as copper salt) to obtain iodobenzene. Subsequently, iodobenzene is brominated, and the bromine atom enters the benzene ring. Because iodine is an ortho-para-localization group, 1-bromo-4-iodobenzene can be obtained. The subsequent alkylation steps are the same as the previous method to obtain the target product.
Third, benzene can also be alkylated first. Benzene and halogenated trimethylmethane under the action of the catalyst to obtain trimethylbenzene. Then bromination, because the alkyl group is an ortho-ortho-locator, bromine enters the ortho-ortho-locator, and then iodine is substituted to obtain 1-bromo-4-iodine-2 - (trimethyl) benzene. This general preparation method has its own advantages and disadvantages, and should be selected according to the actual materials and conditions.
What are the precautions for the use of 1-bromo-4-chloro-2- (trifluoromethyl) benzene?
1 + -Hg-4 + -arsenic-2 + - (triethyl) ether This material should be paid attention to many matters during use.
Mercury is a highly toxic metal element. It is liquid at room temperature and is volatile, and its vapor is extremely toxic. If exposed to mercury-containing 1 + -Hg-4 + -arsenic-2 + - (triethyl) ether, avoid the volatilization of mercury into the body. Use in a well-ventilated place. If conditions permit, install ventilation devices to prevent the accumulation of mercury vapor. And it is appropriate to wear protective clothing, gloves and masks during operation to avoid skin contact and inhalation. Once mercury spills, do not touch it with your hands. Cover it with sulfur powder as soon as possible to form mercury sulfide, reduce toxicity, and then clean it up properly.
Arsenic is also a toxic element. 1 + -mercury-4 + -arsenic-2 + - (triethyl methyl) ether containing arsenic should not be eaten by mistake or exposed to damaged skin. Accidental consumption of arsenide can cause acute poisoning and endanger life; long-term exposure to small amounts can also cause chronic poisoning and damage multiple organ functions.
Furthermore, the chemical properties of 1 + -mercury-4 + -arsenic-2 + - (triethyl methyl) ether itself should also be paid attention to. It may be flammable, oxidizing or react violently with other substances. When using, keep away from fire and heat sources, and avoid co-storage or mixing with strong oxidizing agents, reducing agents and other substances that may cause dangerous reactions. After use, store properly, place in a cool, dry and ventilated place, and clearly mark to prevent accidental use. During operation, if you accidentally come into contact with skin or eyes, rinse with plenty of water immediately and seek medical treatment in time.