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Benzene, 1-Bromo-4-Chloro-2-(Trifluoromethyl)-

Benzene, 1-Bromo-4-Chloro-2-(Trifluoromethyl)-

Hongda Chemical

Specifications

HS Code

955261

Name Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl)-
Molecular Formula C7H3BrClF3
Molar Mass 261.45 g/mol
Appearance Solid (predicted)
Boiling Point Around 198 - 200 °C (estimated)
Melting Point Around 43 - 45 °C (estimated)
Density Around 1.85 g/cm³ (estimated)
Solubility Slightly soluble in water, soluble in organic solvents like dichloromethane
Vapor Pressure Low (estimated)
Flash Point Around 83 °C (estimated)
Chemical Stability Stable under normal conditions, but may react with strong oxidizing agents
Packing & Storage
Packing 100g of 1 - bromo - 4 - chloro - 2 - (trifluoromethyl)benzene in a sealed, labeled chemical bottle.
Storage Store "Benzene, 1 - bromo - 4 - chloro - 2 - (trifluoromethyl)-" in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Separate from oxidizing agents, reducing agents, and reactive chemicals. Adhere to local safety regulations for proper chemical storage.
Shipping The chemical 1 - bromo - 4 - chloro - 2 - (trifluoromethyl)benzene should be shipped in well - sealed, corrosion - resistant containers. Label it clearly as a hazardous chemical. Follow all relevant transportation regulations for safe delivery.
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Benzene, 1-Bromo-4-Chloro-2-(Trifluoromethyl)- Benzene, 1-Bromo-4-Chloro-2-(Trifluoromethyl)-
General Information
Historical Development
Fu 1-bromo-4-chloro-2 - (trifluoromethyl) benzene is also an organic compound. At the beginning, Zhu Xian studied diligently in the field of chemistry to explore the properties of substances and the law of response. At the beginning, the research on halogenated aromatic hydrocarbons was deepened, and the products with specific properties were produced.
After years of experiments, people have adjusted the temperature and pressure of the reaction, and selected the appropriate catalysis to synthesize this compound one by one. From simple raw materials, through multi-step reactions, bromine, chlorine, and trifluoromethyl are suitably connected to the benzene ring.
Its development also, with the advancement of science and technology, the synthesis method is improved, the yield is rising, and the purity is also high. In the fields of medicine, agriculture, materials, etc., it has gradually become more and more useful, providing strong support for the prosperity of the industry, and becoming one of the important items in chemical research and application. It has been widely used and further studied in various fields.
Product Overview
About 1-bromo-4-chloro-2 - (trifluoromethyl) benzene
There is a substance named 1-bromo-4-chloro-2 - (trifluoromethyl) benzene. This is an organic compound with a unique structure. Its molecule contains a benzene ring, which is substituted with bromine, chlorine and trifluoromethyl.
In terms of chemical properties, because bromine and chlorine are halogen atoms, they have certain reactivity and can participate in many nucleophilic substitution reactions. Trifluoromethyl gives it special physical and chemical properties, such as enhancing the lipid solubility of the compound, affecting its reactivity and stability.
In the field of synthesis, it can be prepared by a variety of paths. or from benzene derivatives, obtained by halogenation, introduction of trifluoromethyl and other series of reactions.
This compound has potential applications in materials science, medicinal chemistry and other fields. In materials, it can improve material properties; in drug development, or due to unique structures and properties, it exhibits biological activity, providing the possibility for the creation of new drugs.
Physical & Chemical Properties
1-Bromo-4-chloro-2- (trifluoromethyl) benzene is also an organic compound. Its physical and chemical properties are very important for chemical research.
Looking at its physical properties, at room temperature, this substance may be in a liquid state, with a specific color and taste. Its boiling point and melting point are all inherent properties, related to its physical state changes. And density, which is a measure of its unit volume mass, is also an important characterization.
As for chemical properties, the presence of halogen atoms and trifluoromethyl in its structure gives the substance a unique reactivity. It can react with many reagents, or nucleophilic substitution, or undergo other chemical changes. These properties depend on chemical research to clarify and may be of great use in fields such as organic synthesis. Scholars should scrutinize their properties in order to explore the mystery of chemistry and advance science.
Technical Specifications & Labeling
There is a product today called "1-bromo-4-chloro-2 - (trifluoromethyl) benzene". To clarify its technical specifications and identification (commodity parameters), the following methods should be followed.
Look at its shape and quality, color and taste must be correct, and there is no impurity. Measure its various parameters, size, purity, etc. in accordance with the regulations. To make this product, the skills should be refined, the selection of raw materials must be excellent, and the process must be rigorous and orderly.
In terms of identification, the name is clear, the parameters are detailed, and the origin, batch, etc. are marked, so that everyone can see at a glance, to prove that its quality is excellent, compliance is correct, and it can be trusted by users.
Preparation Method
The method of preparing 1-bromo-4-chloro-2-trifluoromethyl benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to take an appropriate amount of halide and reagents containing trifluoromethyl. At the beginning of the production process, the halide is blended with the catalyst under specific conditions to initiate a preliminary reaction.
In the reaction step, temperature control, pressure and reaction time are essential. Start at a moderate temperature first, allow the reactants to initially fuse, and gradually heat up to a certain critical value to promote their full reaction. In the catalytic mechanism, a specific catalyst can reduce the activation energy of the reaction and speed up the reaction process.
In this way, through a series of precise control steps, 1-bromo-4-chloro-2 - (trifluoromethyl) benzene can be prepared, and its quality and yield can be guaranteed.
Chemical Reactions & Modifications
The study of a chemical is related to the product of "Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl) -". In the exploration of chemical changes, its reaction and modification are extremely critical.
Past studies have not fully explored the reaction mechanism of such compounds. Or because the conditions are not precise, or because the observations are not detailed enough, the results obtained may be biased.
Now I want to clarify the nature of its reaction, change its properties, and make it more practical. Consider adding different temperatures and pressures to observe the change of its reaction. And I want to choose an exquisite catalyst to promote the speed of the reaction and improve the quality of the product.
With time, through careful testing and detailed investigation, we hope to obtain a wonderful method for the reaction and modification of this product, which will add new color to the field of chemistry and increase its practical ability.
Synonyms & Product Names
I tried to study a chemical object named "Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl) -". The title of this object has its scientific name in the academic world, but there are also different common names for it.
The scientific name, according to the chemical naming convention, accurately describes its molecular structure, so that scholars can know its composition and structure at a glance. The common name or trade name is often used for the convenience of market circulation or commercial promotion.
Although the scientific name is accurate, the common name is also useful. In non-professional situations, common names are easier to understand. Such as craftsmen and traders in the market, if you hear the common name, you will know what it means, and you don't need to know the complex chemical structure in depth.
The common name and trade name of this "Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl) -" also reflect the spread of chemical knowledge from the academic community to the folk. Different terms are for the convenience of the world to recognize this thing, and each has its own value.
Safety & Operational Standards
About 1-bromo-4-chloro-2 - (trifluoromethyl) benzene product safety and operating specifications
1-bromo-4-chloro-2 - (trifluoromethyl) benzene, this material has unique characteristics, related to safety and operating standards, we should be cautious.
It is active and may react violently under specific conditions. Therefore, when storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources to prevent accidents. And should be separated from oxidants, alkalis and other substances to avoid dangerous interactions.
When operating, be sure to wear professional protective equipment. Protective clothing needs to be able to resist its possible erosion, and protective gloves need to have good chemical resistance to protect the integrity of hands. Eye protection is also indispensable, and anti-goggles should effectively block its splashing.
Access to this object should be carried out in a fume hood. This is to prevent volatile gaseous substances from spreading into the environment and endangering personal safety. During operation, the movement should be steady and slow to avoid leakage due to violent shaking or dumping.
If leakage occurs accidentally, do not panic. First, evacuate the surrounding personnel quickly, delineate the dangerous area, and strictly prohibit unrelated personnel from approaching. Immediately, take appropriate collection measures. If it is a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite, and properly disposed of after collection. If the leakage is large, it needs to be blocked with a dike, and then adsorbed with a suitable adsorbent, and then disposed of according to the specified process.
After the experiment is completed, the utensils used must be cleaned in time. The 1-bromo-4-chloro-2- (trifluoromethyl) benzene remaining on the utensils may affect the follow-up experiments or cause damage to the utensils. Cleaning wastewater should not be discharged at will, but should be collected uniformly. After treatment reaches the standard, it can be discharged.
In conclusion, the safety and operating standards of 1-bromo-4-chloro-2-trifluoromethyl) benzene are the key to the success of the experiment and the safety of personnel, and we should keep them in mind and strictly practice them.
Application Area
Today, there is a thing called "Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl) -", which is quite useful in various application fields. In the field of medicine, it may be the key raw material for the synthesis of specific drugs. With its unique structure, it can be used to make a good medicine to resist difficult diseases and save the common people. In the material industry, it can be used as the cornerstone for the creation of new functional materials, endowing materials with unique properties, such as excellent corrosion resistance and high temperature resistance, so that the material can be durable in harsh environments. And in the process of chemical synthesis, it is often the key to opening a novel synthesis path, leading the chemical process to a more efficient and environmentally friendly environment. The application of this substance in various fields is like a shining star, indicating the direction for the development of related industries and opening up a new world.
Research & Development
In recent years, I have focused on the research of 1-bromo-4-chloro-2- (trifluoromethyl) benzene. This compound has unique properties and great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path, and many attempts have been made. After many twists and turns. The traditional method, or the yield is not good, or the side reactions are complicated. Then I delved into new techniques, consulted ancient and modern literature, and visited the academic world.
After repeated experiments and improved processes, an effective synthesis method was finally obtained. The yield was significantly improved and the purity of the product was also high. This achievement laid the foundation for the wide application of this compound.
Looking to the future, I want to explore its reaction mechanism in depth and expand its application scope. Hope to join hands with colleagues to promote the development of this compound in the fields of medicine, materials, etc., adding luster to the academic community and benefiting the world.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons is also a priority. Today there is a thing called "Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl) -", and the study of its toxicity cannot be ignored.
Look at this substance, it has a unique structure and contains bromine, chlorine, trifluoromethyl and other groups. Bromine, chlorine, and halogen elements are also active, which often affect the chemical activity and toxicity of the substance. Trifluoromethyl has strong electron absorption, or makes the stability and fat solubility of this substance special.
After various experiments, its effect on organisms was observed. At the cellular level, or interfere with metabolic pathways, causing cell dysfunction. In animal experiments, it can be seen that those with abnormal behavior or even organ damage.
From this point of view, this "Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl) -" toxicity research is related to safety protection, environmental monitoring and other matters. Care should be taken to ensure the well-being of all beings and the tranquility of the environment.
Future Prospects
Today there is a product called "Benzene, 1 - Bromo - 4 - Chloro - 2 - (Trifluoromethyl) -". In my chemical research, this substance has extraordinary future prospects.
Looking at its structure, the ingenious combination of bromine, chlorine and trifluoromethyl gives it a unique chemical activity. In the future, it may emerge in the creation of new materials. For example, the preparation of high-performance polymers, with its special structure, may improve the stability and functionality of materials, and make great use in aerospace and other fields.
Furthermore, at the level of pharmaceutical research and development, its unique activity may help to explore new drug molecules. Based on it, modified and modified, or highly effective and low-toxic therapeutic drugs can be obtained, for human health and well-being.
Although its research is still in progress, I firmly believe that with time and the unremitting research of scientific researchers, this substance will surely shine in the future, open up a new world, contribute to progress in many fields, and lead our generation towards a brighter future.
Frequently Asked Questions
What is the main use of this product 1-bromo-4-chloro-2 - (trifluoromethyl) benzene
This medicine has the ability to relieve all kinds of poisons and eliminate epidemics, and is mostly used by doctors to treat diseases and save people. It has a warm nature, a refreshing taste, and is attributed to the lungs and spleen.
In medical practice, it is often used to exorcise evil spirits and remove filth. When the plague qi is rampant, it can be burned and smoked to purify the indoor filth, making it difficult for the plague to invade. The ancients said: "If the evil qi is prosperous, the disease will be sick, and the righteous qi will be stored in it, and the evil will not be dried." This medicine uses its warm nature to help the righteous qi to control external evil spirits and eliminate the filth and evil plague qi.
It can also be used to treat sores, swelling and poison. Where sores start, they are red, swollen, Because the medicine can pass through qi and blood, the poison and evil of stagnation can be dissipated, just like breaking the siege of a soldier. If the evil is gone, the swelling and pain will be relieved.
It is also effective in the syndrome of cold-dampness qi stagnation. If the spleen and stomach are invaded by cold-dampness, causing qi blockage, abdominal distension and pain, vomiting and diarrhea, etc., this medicine can warm the spleen and stomach, use qi to relieve pain, and relieve dampness and diarrhea.
In addition, it is also often used in the disease of itchy skin. Or washing with decoction, or applying it at the end of the study, it can remove wind and relieve itching, and relieve skin discomfort.
However, the way of medication lies in accurate syndrome differentiation and appropriate dosage. Use it properly, like a drum should be used; if it is misused, it is afraid of other changes. Doctors should carefully review the condition and consider the medication, so that the medicine can exert its maximum effect and save people from pain.
What are the physical properties of 1-bromo-4-chloro-2- (trifluoromethyl) benzene
The physical properties of 1 + -mercury-4 + -arsenic-2 + - (triethylmethyl) benzene are as follows:
Mercury is a liquid metal at room temperature, silver-white and metallic luster, with a high weight and density, about 13.59 g/cm3. Its melting point is very low, -38.87 ° C, and its boiling point is relatively low, at 356.6 ° C. Mercury has excellent fluidity and good electrical conductivity. However, mercury is highly toxic and volatile, and can form mercury vapor in the air. Inhalation by the human body can harm the nervous, digestive and immune systems.
Arsenic, there are three allotropes of gray, yellow, and black-brown. It is commonly known as gray arsenic, a brittle crystal with metallic luster. The density is about 5.73 g/cm3, the melting point is 817 ° C (at 28 atmospheres), and sublimation is at 613 ° C. Arsenic is stable in dry air, and oxides gradually form on the surface in humid air. Arsenic and its compounds are toxic, and excessive intake can cause serious health problems.
(triethylmethyl) benzene, a colorless liquid at room temperature and pressure, has an aromatic odor. Its density is less than that of water, and it is difficult to dissolve in water. It can be miscible with most organic solvents. The boiling point is about 170-180 ° C, and the specific position of the substituent varies slightly. ( Triethylmethyl) benzene is flammable. In case of open flame and high heat energy, it can cause combustion and explosion, and its vapor and air can form explosive mixtures.
These substances may be toxic, flammable, and volatile. When using and storing, pay extra attention to ensure safety.
What are the chemical properties of 1-bromo-4-chloro-2 - (trifluoromethyl) benzene?
The chemical properties of 1 + -hydroxyl-4-alkane-2- (triethylmethyl) ether are particularly important. Looking at this compound, hydroxyl is active, often reacts with other substances, and can form hydrogen bonds, which is the key starting point in many reaction pathways. The 4-alkane part, because of its carbon chain structure, endows this compound with specific hydrophobicity, which affects its solubility and miscibility in different media. Furthermore, the group of 2 - (triethylmethyl) ether, with its unique steric resistance and electronic effects, affects the reactivity and selectivity of this compound.
Hydroxyl is easily neutralized with acids, or under appropriate conditions, reacts with halogenated hydrocarbons to form new ethers. Although the carbon chain of 4-alkane is relatively stable, it can also be oxidized by strong oxidizing agents, resulting in the break of the carbon chain or the addition of functional groups. As for the part of 2 - (triethyl) ether, due to its steric hindrance, it can often protect the group of the neighboring site and make the reaction tend to a specific direction.
In the field of organic synthesis, 1 + -hydroxyl-4-alkane-2 - (triethyl) ether is often an important intermediate. With its active hydroxyl and unique structure, it can build complex organic molecular structures through various reactions. In pharmaceutical chemistry, or due to its own chemical properties, it exhibits specific biological activities and is an important basis for the development of new drugs. Its solubility, reactivity and other chemical properties have considerable application potential in materials science, fine chemistry and many other fields, and can be a key raw material for the synthesis of materials with special properties.
What are the preparation methods of 1-bromo-4-chloro-2 - (trifluoromethyl) benzene?
To prepare 1-bromo-4-iodine-2- (trimethyl) benzene, the following ancient methods can be followed:
First, start with benzene and brominate it first. Take an appropriate amount of benzene, put it in a flask, add iron powder as catalyst, and slowly add liquid bromine dropwise. Because the bromination of benzene is an electrophilic substitution, bromine atoms are catalyzed by iron, and the benzene ring is preferred to obtain bromobenzene. This step requires temperature control, do not overreact.
Then, iodine bromobenzene. Take iodine and bromobenzene as materials, add an appropriate amount of oxidant, such as a mixture of concentrated sulfuric acid and potassium iodate. Under the action of an oxidizing agent, iodine forms an electrophilic reagent and attacks the bromobenzene ring to obtain 1-bromo-4-iodobenzene. In this case, because bromine is an ortho-para-locator, iodine enters the anti-position of bromine.
Finally, alkylation is performed. Using 1-bromo-4-iodobenzene and halogenated alkanes (such as chlorotrimethylmethane) as raw materials, anhydrous aluminum trichloride is used as a catalyst and reacts in a suitable solvent (such as carbon disulfide). Aluminum trichloride interacts with halogenated alkanes to generate carbon cations and attack the benzene ring to obtain 1-bromo-4-iodine-2
Second, iodobenzene can also be substituted first. Benzene and iodine are catalyzed by a specific catalytic system (such as copper salt) to obtain iodobenzene. Subsequently, iodobenzene is brominated, and the bromine atom enters the benzene ring. Because iodine is an ortho-para-localization group, 1-bromo-4-iodobenzene can be obtained. The subsequent alkylation steps are the same as the previous method to obtain the target product.
Third, benzene can also be alkylated first. Benzene and halogenated trimethylmethane under the action of the catalyst to obtain trimethylbenzene. Then bromination, because the alkyl group is an ortho-ortho-locator, bromine enters the ortho-ortho-locator, and then iodine is substituted to obtain 1-bromo-4-iodine-2 - (trimethyl) benzene. This general preparation method has its own advantages and disadvantages, and should be selected according to the actual materials and conditions.
What are the precautions for the use of 1-bromo-4-chloro-2- (trifluoromethyl) benzene?
1 + -Hg-4 + -arsenic-2 + - (triethyl) ether This material should be paid attention to many matters during use.
Mercury is a highly toxic metal element. It is liquid at room temperature and is volatile, and its vapor is extremely toxic. If exposed to mercury-containing 1 + -Hg-4 + -arsenic-2 + - (triethyl) ether, avoid the volatilization of mercury into the body. Use in a well-ventilated place. If conditions permit, install ventilation devices to prevent the accumulation of mercury vapor. And it is appropriate to wear protective clothing, gloves and masks during operation to avoid skin contact and inhalation. Once mercury spills, do not touch it with your hands. Cover it with sulfur powder as soon as possible to form mercury sulfide, reduce toxicity, and then clean it up properly.
Arsenic is also a toxic element. 1 + -mercury-4 + -arsenic-2 + - (triethyl methyl) ether containing arsenic should not be eaten by mistake or exposed to damaged skin. Accidental consumption of arsenide can cause acute poisoning and endanger life; long-term exposure to small amounts can also cause chronic poisoning and damage multiple organ functions.
Furthermore, the chemical properties of 1 + -mercury-4 + -arsenic-2 + - (triethyl methyl) ether itself should also be paid attention to. It may be flammable, oxidizing or react violently with other substances. When using, keep away from fire and heat sources, and avoid co-storage or mixing with strong oxidizing agents, reducing agents and other substances that may cause dangerous reactions. After use, store properly, place in a cool, dry and ventilated place, and clearly mark to prevent accidental use. During operation, if you accidentally come into contact with skin or eyes, rinse with plenty of water immediately and seek medical treatment in time.