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Benzene, 1-Bromo-4-(1,1-Difluoroethyl)-

Benzene, 1-Bromo-4-(1,1-Difluoroethyl)-

Hongda Chemical

Specifications

HS Code

844988

Chemical Formula C8H7BrF2
Molecular Weight 221.04
Solubility In Water Low, as it is an organic compound with non - polar benzene ring and fluorinated alkyl group
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate

As an accredited Benzene, 1-Bromo-4-(1,1-Difluoroethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - bromo - 4 - (1,1 - difluoroethyl)benzene in 100 - gram bottles for chemical packaging.
Storage **Storage of 1 - bromo - 4 - (1,1 - difluoroethyl)benzene**: Store this chemical in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Separate it from oxidizing agents, acids, and bases. Label the storage clearly for easy identification and ensure compliance with safety regulations.
Shipping 1 - Bromo - 4 - (1,1 - difluoroethyl) benzene is shipped in specialized containers compliant with chemical transport regulations. These containers prevent leakage, ensuring safe transit of this potentially hazardous chemical.
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Benzene, 1-Bromo-4-(1,1-Difluoroethyl)- Benzene, 1-Bromo-4-(1,1-Difluoroethyl)-
General Information
Historical Development
In the field of chemistry, 1-bromo-4 - (1,1-difluoroethyl) benzene is gradually emerging. Looking back at its past, it was explored at the beginning, but everyone did not know its properties. Scientists who study hard, after several years, have achieved something.
In the past, chemical masters used their efforts to explore the secrets of matter. In the process of organic synthesis, they tried many times to obtain this compound. At the beginning, the method was not good, and the yield was quite low. However, scholars were discouraged and made unremitting improvements.
After years of tempering, the method of synthesis has been perfected day by day. From the beginning of difficulty, to now it can be produced more efficiently. Its application is also becoming more and more extensive, in medicine, materials and other fields, all of which are reflected in its application. The spirit of past exploration has made today's progress. This is the way of scientific research.
Product Overview
A new product of a certain day is called 1-bromo-4- (1,1-difluoroethyl) benzene. Its substance is also an organic compound, like a colorless to slightly yellow liquid, with a special odor. This product has a wide range of uses in the chemical industry, and can be used as an intermediate to participate in the synthesis of a variety of fine chemicals.
Its preparation method follows the conventional path of organic synthesis, through halogenation and substitution reactions. During synthesis, it is necessary to strictly control the reaction conditions, such as temperature, pressure, and catalyst dosage, in order to obtain high-purity products.
1-bromo-4- (1,1-difluoroethyl) benzene is chemically active and can react with many reagents to derive other compounds. However, it also has certain risks. When using it, safety procedures must be followed and protective measures must be taken to avoid harm.
Physical & Chemical Properties
About the physicochemical properties of 1-bromo-4- (1,1-difluoroethyl) benzene
Now there is a thing, named 1-bromo-4- (1,1-difluoroethyl) benzene. Its physical properties, viewed at room temperature, are like colorless to pale yellow liquids with a special odor. The boiling point is considerable, about a specific temperature range, which is caused by factors such as intermolecular forces. Its density is also a characteristic. It is heavier than water. When placed in water, it will sink.
When it comes to chemical properties, the structure of the benzene ring gives it a certain stability. However, the existence of bromine atoms and difluoroethyl groups adds to the activity. The bromine atom can participate in the nucleophilic substitution reaction, and can be replaced by other groups in the case of appropriate reagents. The fluorine atom in difluoroethyl group has strong electronegativity, which affects the distribution of molecular electron clouds, so that the substance exhibits unique activity in some reactions. The coexistence of its chemical activity and stability is really an interesting point for research, which can provide new possibilities for many chemical synthesis paths.
Technical Specifications & Labeling
There is now a product called 1-bromo-4- (1,1-difluoroethyl) benzene. Its process specifications and identification (product parameters) should be carefully studied. Those who standardize the process, the method of making this product is also determined, from the precision of material selection to the order of steps. The material needs to be pure, and the method needs to be correct, in order to get a good product. The marker, clarify its nature, its amount, and its use. This 1-bromo-4- (1,1-difluoroethyl) benzene must be marked with the accuracy of its ingredients, the characteristics of its properties, the suitability of its use, and the suitability of storage. In this way, the user can know its details, operate it correctly, and use it properly. Craftsmanship and labeling complement each other and are essential to the product.
Preparation Method
To prepare 1-bromo-4- (1,1-difluoroethyl) benzene, the method is as follows:
The preparation of raw materials requires a substrate containing benzene, and a reagent containing bromine and difluoroethyl. The preparation process first substitutes benzene and bromine under suitable catalytic conditions, and introduces bromo groups to obtain bromobenzene. This step requires controlling the temperature and reaction time to make the reaction sufficient.
The second time is to use bromobenzene and a reagent containing difluoroethyl group. After specific reaction steps, in the appropriate reaction environment, such as the presence of specific solvents and catalysts, the difluoroethyl group is connected to the phenyl cyclobromide group. This process requires attention to the precise regulation of the reaction conditions so that the reaction proceeds to the target product.
A reasonable feedback mechanism needs to be established to monitor the reaction process in real time, and adjust the reaction parameters such as temperature and reagent dosage in a timely manner according to the formation of the product and the remaining raw materials.
And an activation mechanism is set up, either by heating, lighting, or by using a specific catalyst to activate the reactant to increase its reactivity, so as to promote the efficient completion of the reaction, so that 1-bromo-4- (1,1-difluoroethyl) benzene can be obtained.
Chemical Reactions & Modifications
The chemical substance of Guanfu is named "Benzene, 1 - Bromo - 4 - (1,1 - Difluoroethyl) -", and its reaction and modification are of great importance to chemical research.
In the past, the reaction of this substance was mostly investigated by conventional methods, but the effect was not satisfactory. The reaction conditions are harsh, or the yield is not high, and the product purity is not good.
Today, if you want to change its shape, you must think of new ways. Or find a special catalyst to promote the smooth reaction and increase the yield; or adjust the temperature and pressure of the reaction, and precisely control it to optimize the product performance.
It can also start from the structure, analyze its chemical health characteristics in detail, and use the method of modification to make the material have new qualities, and develop its talents in the fields of medicine and materials. This is all for chemical researchers to diligently explore, so as to achieve the great cause of chemical product reaction and modification.
Synonyms & Product Names
I have heard that there is a thing called 1-bromo-4- (1,1-difluoroethyl) benzene. In the world, it may have another name, or it may have a business name.
The nickname of this thing is due to the differences in people's cognition, use, and origin. Or because of its shape, its nature, and its origin, it gets another name, but it all refers to the same thing.
As for the business name, in order to recognize its characteristics and attract customers' favor, the merchant will also make another good name. Or to show its purity, or to say its efficacy, and so on.
Although the names are different, there is no doubt that its essence is 1-bromo-4- (1,1-difluoroethyl) benzene. This is the essence of chemistry, the substance is constant, and the name can be proliferated. Only by studying its root can we get the true meaning.
Safety & Operational Standards
Code of Safety and Operation for 1-Bromo-4- (1,1-difluoroethyl) benzene
Fu 1-bromo-4- (1,1-difluoroethyl) benzene is a special chemical product. It is related to safety and operation standards and is extremely important and cannot be ignored.
In terms of storage, choose a cool, dry and well-ventilated place. Avoid open flames, hot topics, and keep away from fire sources. This is essential for fire prevention. Because of its flammability, if it is not careful, it will be dangerous to ignite. The reservoir must also be sealed to prevent leakage, pollute the environment, and endanger everyone.
When operating, appropriate protective equipment must be used. Such as protective glasses, which can protect the eyes from splashing liquid; gas masks, which can block harmful gases from entering the body; protective gloves, so that the skin does not touch poisons. The operation room also needs to be well ventilated, so that the volatile gas can dissipate quickly, so as not to accumulate and cause danger.
If a leak unfortunately occurs, quickly cut off the fire source to avoid explosion disaster. Personnel immediately evacuate to a safe place, set up a warning area, and prevent unrelated people from entering. Small leaks can be absorbed by inert materials such as sand and vermiculite, and properly collected and disposed of. If a large number of leaks, it is necessary to build a dike or dig a pit to contain them, and transfer them to a special container with an explosion-proof pump, and hand them over to a professional.
First aid methods must also be familiar with. In case of skin contact, quickly remove dyed clothes, rinse with plenty of water, and seek medical treatment. Eye contact, lift eyelids, rinse with flowing water or normal saline, also need to seek medical attention. If inhaled, quickly move to a fresh air place to keep breathing unobstructed, breathing difficulties will give oxygen, breathing will stop, that is, artificial respiration, and emergency medical treatment.
In short, in the operation and use of 1-bromo-4- (1,1-difluoroethyl) benzene, it is necessary to strictly abide by safety and operating standards to ensure people's safety and physical integrity and avoid disasters.
Application Area
In today's chemical research, there is a product called "Benzene, 1 - Bromo - 4 - (1,1 - Difluoroethyl) -". Its application field is quite wide. In the field of pharmaceutical research and development, this compound can be used as a key intermediate to help synthesize special drugs, which is expected to overcome difficult diseases and add a weapon for doctors to treat diseases. In the field of materials science, with its unique chemical properties, it can create new functional materials, or have excellent optical and electrical properties, which can be used in electronic devices, optical instruments, etc. In the field of agrochemical, it can be used to develop high-efficiency and low-toxicity pesticides, which can not only protect crops from pests, but also reduce environmental damage and protect ecological balance. From this perspective, "Benzene, 1 - Bromo - 4 - (1,1 - Difluoroethyl) -" is of great value in many practical fields and has broad prospects. It is up to our researchers to explore it in depth and make the best use of it.
Research & Development
A certain daily chemical company studied this substance, named "1-bromo-4- (1,1-difluoroethyl) benzene". The way of this research is related to its quality, performance and use, and seeks to improve it, so as to benefit people's livelihood.
At the beginning, explore its structure, analyze its composition, understand the structure of molecules, and understand the connection of atoms. Then, study the physical properties, know its color, taste, melting, and observe the state of dissolution and density. Chemical properties are also important. It is also important to observe its response to other substances, find the rules of reaction, and explore the mechanism.
The road to research and development is quite difficult. To obtain high-purity substances requires precise control of conditions and improved processes. Taking into account cost and environmental protection, we strive to balance efficiency and ecology. However, with unremitting research, progress has been made. Today, this product has emerged in various fields, or is used in medicine to help heal diseases; or is used in fragrances to add fragrance to life. In the future, we should continue to explore, expect it to be better, and make unremitting progress for research and progress.
Toxicity Research
The derivative of benzene under investigation, named 1-bromo-4- (1,1-difluoroethyl) benzene, is related to its toxicity and cannot be ignored. Investigate its properties in detail to understand its effects on life. Looking at this substance, it has a unique structure. Fluorine and bromine are attached to the benzene ring, or cause abnormal toxicity. After various experiments, it can be caused by probing its path into the body, or by breathing, or through the skin. In animal tests, observe its symptoms, observe the changes in its organs, and know the toxicity. Or damage the ability of liver and kidney, or disrupt the nervous system. Toxicity research is the foundation of protection, hoping to clarify its harm, in order to take a comprehensive policy, to protect the public from danger, so that the use of this substance is in the safe domain, not a scourge.
Future Prospects
I study chemical things, and now I look at "Benzene, 1 - Bromo - 4 - (1,1 - Difluoroethyl) -" This product has a vision of the future in mind. This product may shine on the road of medical creation. With its unique structure, it may be able to create new treatments for new diseases and create new methods. In the field of material science, it is also expected to emerge, or it may help to develop new materials with strange properties for high-tech. Although the road ahead is long, I am convinced that with time and unremitting research, this product will be as bright as a star, illuminating the unknown, bringing benefits to the world, developing its infinite potential, and opening up a new chapter in the future.
Where to Buy Benzene, 1-Bromo-4-(1,1-Difluoroethyl)- in China?
As a trusted Benzene, 1-Bromo-4-(1,1-Difluoroethyl)- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzene, 1-Bromo-4-(1,1-Difluoroethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of 1-Bromo-4- (1,1-Difluoroethyl) -Benzene?
1 - Bromo - 4 - (1,1 - Difluoroethyl) - Benzene is also a compound. It is made of benzene, on which one is connected to a bromine atom, and the other is connected to 1,1 - difluoroethyl.
Benzene is a planar hexadecimeter formed by a total of six carbon atoms, which is aromatic. Bromine atom, with one carbon atom of benzene. 1,1 - difluoroethyl, ethyl, and ethane molecules are formed by removing one atom, of which one carbon atom is benzene, and this carbon atom has a fluorine atom.
Therefore, the chemical properties of 1 - Bromo - 4 - (1,1 - Difluoroethyl) - Benzene are formed by the bonding of specific atoms and groups at the core of benzene, which gives the specific physical properties of compounds. It may have its uses in various fields such as synthesis.
Where is 1-Bromo-4- (1,1-Difluoroethyl) -Benzene used?
1-Bromo-4- (1,1-difluoroethyl) benzene is used in many fields. In the field of pharmaceutical and chemical industry, it is often a key intermediate. Because fluorinated organic compounds are very popular in drug development, the introduction of fluorine atoms can significantly change the physical, chemical and biological activities of compounds. This compound can be combined with other reagents through a specific reaction path to obtain drug molecules with specific pharmacological activities, which can be used as antibacterial and antiviral drugs, or play an important role in the creation of drugs for the treatment of nervous system diseases.
It also has potential value in the field of materials science. It can be used to synthesize new fluorine-containing polymer materials. Fluoropolymers often have excellent chemical stability, thermal stability, and low surface energy. Using this compound as a raw material, through polymerization and other means, it is expected to produce high-performance materials for special occasions, such as high and low temperature resistance and corrosion resistance materials in the aerospace field, or materials for insulation and anti-fouling coatings in the electronics industry.
In the field of pesticide chemistry, 1-bromo-4- (1,1-difluoroethyl) benzene is also useful. Fluorinated pesticides usually show the advantages of high efficiency, low toxicity, and environmental friendliness. With this as a starting material, through a series of reactions, pesticide products with strong pest resistance and low impact on the environment can be prepared, providing strong support for agricultural pest control.
Furthermore, in the study of organic synthetic chemistry, it is an important synthetic block. Organic chemists can carry out various novel organic reaction studies by chemical modification of bromine atoms and difluoroethyl groups, expand organic synthesis methodologies, provide new ideas and new methods for the synthesis of more complex organic compounds, and promote the development of organic synthetic chemistry.
What are the physical properties of 1-Bromo-4- (1,1-Difluoroethyl) -Benzene?
1-Bromo-4- (1,1-difluoroethyl) benzene is one of the organic compounds. Its physical properties are quite impressive, let me tell you in detail.
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid, with a clear texture, like a clear spring, but contains a unique chemical mystery. Its smell, although not pungent and intolerable, also has a special smell, which seems to have a faint fragrance hidden in it, and needs to be carefully distinguished to be detectable.
When it comes to boiling point, this compound boils at about a certain temperature. Specifically, its boiling point will vary slightly depending on the environmental pressure. In the environment of standard atmospheric pressure, its boiling point is in a specific range, and this temperature is enough to transform it from liquid to gaseous state, just like a phoenix nirvana, undergoing a transformation of form.
In terms of melting point, it exhibits another characteristic. Under specific low temperature conditions, 1-bromo-4- (1,1-difluoroethyl) benzene will solidify from a flowing liquid state to a solid state, just like time solidification, showing a different static beauty. The value of its melting point is also an important indicator of the physical properties of the compound.
Furthermore, density is also a physical property that cannot be ignored. Its mass per unit volume makes this compound occupy a unique position in the material world. Compared with common organic solvents, its density is either light or heavy, which affects its performance in various chemical reactions and practical applications.
Solubility is also a major feature of this compound. 1-Bromo-4- (1,1-difluoroethyl) benzene has good solubility in organic solvents such as ethanol and ether, just like fish entering water, it can blend with it and integrate seamlessly. However, the solubility in water is extremely limited, just like the incompatibility of oil and water, the two are distinct.
These physical properties are of great significance in many fields such as organic synthesis and materials science. Understanding its physical properties allows for better control of its behavior in various reactions and applications, providing a solid foundation for scientific research and industrial production.
What are the synthesis methods of 1-Bromo-4- (1,1-Difluoroethyl) -Benzene?
There are various ways to synthesize 1-bromo-4- (1,1-difluoroethyl) benzene.
First, it can be started by styrene derivatives. First, styrene and difluorobromoethane are reacted in the presence of a suitable catalyst according to the principle of nucleophilic addition reaction. This reaction requires the selection of a suitable solvent, such as an aprotic solvent, to promote the smooth occurrence of the reaction. The reaction conditions should be mild, and the temperature and pressure should be precisely controlled, so that the reactants can be fully contacted and reacted to form intermediate products containing double bonds. Subsequently, for this intermediate product, a brominating agent, such as bromine elemental or N-bromosuccinimide (NBS), is carried out under the action of light or initiator to carry out a radical bromination reaction to obtain the target product 1-bromo-4- (1,1-difluoroethyl) benzene.
Second, p-bromoacetophenone is used as a raw material. First, p-bromoacetophenone is nucleophilic addition reaction with difluoromethyl Grignard reagent or difluoromethyl lithium reagent. Such organometallic reagents have high activity and can be added to carbonyl groups to form alcohol intermediates. Then, the alcohol intermediate is dehydrated, and acidic reagents such as concentrated sulfuric acid or p-toluenesulfonic acid are often used as catalysts to promote the dehydration of hydroxy groups from adjacent carbons at appropriate temperatures to form carbon-carbon double bonds. Finally, by hydrogenation reduction reaction, the double bond is hydrosaturated, and 1-bromo-4- (1,1-difluoroethyl) benzene can be successfully synthesized.
Third, p-bromotoluene is used as the starting material. First, the methyl activity of p-bromotoluene is used to carry out a radical substitution reaction with difluoromethane under the condition of light or initiator, and difluoromethyl is introduced into the methyl group to form an intermediate product containing difluoromethyl. Then, the benzene ring of the intermediate product is brominated, and the appropriate brominating agent and reaction conditions can be selected to prepare 1-bromo-4- (1,1-difluoroethyl) benzene. This method is relatively simple, but attention should be paid to the selectivity and yield of each step to ensure the effective synthesis of the target product.
What is the market outlook for 1-Bromo-4- (1,1-Difluoroethyl) -Benzene?
1 - Bromo - 4 - (1,1 - Difluoroethyl) - Benzene, this is an organic compound, or 1 - bromo - 4 - (1,1 - difluoroethyl) benzene in Chinese. In today's chemical market, its prospects are quite promising.
In the field of organic synthesis, this compound has a wide range of uses. Due to its unique structure, it contains bromine atoms and difluoroethyl groups, which can be used as key intermediates. Bromine atoms are highly active and can participate in nucleophilic substitution reactions, thereby introducing a variety of functional groups, paving the way for the synthesis of complex organic molecules. For example, in pharmaceutical synthesis, specific nitrogen-containing and oxygen-containing groups can be connected by nucleophilic substitution to create molecules with unique biological activities, which are expected to be used in the research and development of new drugs.
In the field of materials science, it has also emerged. The introduction of fluorine atoms can significantly improve the properties of materials. Fluorinated materials often have good chemical stability, low surface energy and excellent dielectric properties. 1-Bromo-4 - (1,1-difluoroethyl) benzene can be used as a raw material to prepare fluoropolymer materials through polymerization or other reactions. This kind of material can be used as an insulating layer for electronic devices, which can improve the speed and stability of electronic equipment with its low dielectric constant. It can also be used in the field of coatings to give the coating good weather resistance and self-cleaning performance.
Furthermore, with the concept of green chemistry deeply rooted in the hearts of the people, this compound also has room for optimization in the synthesis method. The development of more efficient and environmentally friendly synthesis paths, reducing energy consumption and waste emissions, will definitely meet the market demand for sustainable development, thus further expanding its market application prospects.
To sum up, 1-bromo-4- (1,1-difluoroethyl) benzene has broad application space in many fields such as organic synthesis and materials science due to its own structural characteristics. With technological progress and market demand growth, its market prospects may become brighter.