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Benzene, 1-Bromo-3-Fluoro-2-Methoxy-

Benzene, 1-Bromo-3-Fluoro-2-Methoxy-

Hongda Chemical

Specifications

HS Code

692834

Chemical Formula C7H6BrFO
Molar Mass 205.024 g/mol

As an accredited Benzene, 1-Bromo-3-Fluoro-2-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 1 - bromo - 3 - fluoro - 2 - methoxy - benzene in a sealed chemical - grade bottle.
Storage 1 - bromo - 3 - fluoro - 2 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat and ignition sources. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Separate it from oxidizing agents and reactive substances to prevent potential chemical reactions. Store it in a location accessible only to trained personnel.
Shipping 1 - bromo - 3 - fluoro - 2 - methoxy - benzene is a chemical. Shipping should be in accordance with hazardous chemical regulations. It may require specialized containers, proper labeling, and adherence to transportation safety protocols for safe transit.
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Benzene, 1-Bromo-3-Fluoro-2-Methoxy- Benzene, 1-Bromo-3-Fluoro-2-Methoxy-
General Information
Historical Development
In the past, the field of organic chemistry has no end to exploring. "Benzene, 1 - Bromo - 3 - Fluoro - 2 - oxMethy -" This compound was initially hidden in the abyss of the unknown.
At that time, the sages worked hard to study the structure and reaction of matter. After countless experiments, they found clues in bottles and jars, or in ancient books. Although the thorns are full of roads, those who are determined are unwilling to give up lightly.
Gradually, they have a deeper understanding of its nature and know its potential in the synthesis path. The craftsmen used wisdom as a blade and skills as tools to carve this compound. From ignorance to clarity, from accidental discovery to precise control, its historical evolution is like the stars chasing light, drawing a unique stroke in the long scroll of chemistry, paving the way for the development of organic synthesis in later generations and leading to new frontiers.
Product Overview
Today there is a substance called 1-bromo-3-fluoro-2-methoxybenzene. Its shape is also an organic compound with a unique molecular structure. On the benzene ring, bromine, fluorine, and methoxy groups are arranged according to their positions, and the layout is exquisite.
This substance is quite useful in the field of organic synthesis. Bromine groups are active and can lead to many reactions, adding changes to the structure. The addition of fluorine atoms can change the physical and chemical properties of compounds, such as lipophilicity and stability. Methoxy groups are also non-idle, affecting the distribution of electron clouds in molecules, which is related to reaction activity and selectivity.
In the laboratory, the preparation of this substance requires precise steps, temperature control, speed regulation, selection of appropriate reagents and conditions, before it can be obtained. Looking at its use, it can be used as an intermediate for pharmaceutical synthesis to help create new drugs; or in materials science, it can contribute to the development of novel materials. Its potential is infinite, and we need to explore it in depth to uncover more mysteries and benefit the world.
Physical & Chemical Properties
A certain organic substance, named 1-bromo-3-fluoro-2-methoxybenzene, its physicochemical properties are related to the importance of our research. The color and taste of this substance, at room temperature, may appear as a colorless liquid, the smell has a special fragrance, and many organic compounds have this property.
In terms of its degree of melting and boiling, the melting point is quite low, and it is not easy to solidify in ordinary environments; the boiling point depends on its intermolecular force, and it melts into gas after a little heating. Its solubility, in organic solvents such as ethanol and ether, is quite easy to miscible, and its molecular structure is similar to that of organic solvents.
Then again, its density is lighter than that of water, and it will float on the surface when placed on water. As for the chemical activity, above the benzene ring, bromine, fluorine, and methoxy groups are in their respective positions, making this substance unique to the reaction of electrophilic substitution. Although bromine and fluorine are halogen groups, their reactivity is also different due to the influence of their positions and ortho-methoxy groups. Methoxy groups are the power supply groups, which increase the electron cloud density of the benzene ring, which is conducive to the attack of electrophilic reagents. The electron-absorbing effects of bromine and fluorine have the effect of adjusting the positioning and rate of the reaction. This is all for those who study the quality and physicochemical properties.
Technical Specifications & Labeling
Today there is a product called 1-bromo-3-fluoro-2-methoxybenzene. In the field of chemical industry, its technical specifications and identification (commodity parameters) are crucial.
Looking at this 1-bromo-3-fluoro-2-methoxybenzene, its technical specifications need to be clearly analyzed. The raw materials must be selected, and the reaction conditions must be accurate, such as temperature, pressure, and catalyst. The reaction steps must be orderly, and the transformation of each step is related to the quality of the final product.
In terms of identification (commodity parameters), its purity geometry and impurity content are necessary to measure its quality. Appearance traits cannot be ignored, and color, state, etc. are all the content of the identification. In addition, the parameters of physical and chemical properties, such as melting point, boiling point, solubility, etc., also need to be detailed so that users can make good use of them. In industrial production, scientific research experiments, and many other scenarios, they can be used in accordance with their technical specifications and identification (commodity parameters).
Preparation Method
In order to prepare 1-bromo-3-fluoro-2-methoxylbenzene (Benzene, 1-Bromo-3-Fluoro-2-Methoxy -), the preparation method should be studied in detail. The raw materials and production process, reaction steps and catalytic mechanism.
To prepare this product, you can first take suitable raw materials and react with suitable reaction conditions through fine proportions. First, you need to find suitable starting materials, or compounds containing benzene rings, and add halogenating agents, methoxylating agents, etc. In the reaction step, the benzene ring is halogenated first, and bromine and fluorine atoms are introduced. This step requires temperature control, timing control, and appropriate catalysts are selected to promote the reaction in the desired direction.
After the halogenation is completed, methoxylation is carried out, and the appropriate base and solvent are selected to ensure the smooth integration of the methoxy group into the benzene ring. In this process, the catalytic mechanism is very critical. High-quality catalysts can increase the reaction rate and improve the purity of the product. The whole process requires strict control of each reaction condition and fine operation to obtain this product and become the preparation target.
Chemical Reactions & Modifications
The study of Benzene, 1 - Bromo - 3 - Fluoro - 2 - Methoxy - is very important for chemical reaction and modification. Looking at its structure, bromine, fluorine and methoxy groups are in their respective positions and interact with each other, resulting in unique reaction characteristics.
In many reactions, nucleophilic substitution is a common path. Because the methoxy group has a electron carrier effect, the electron cloud density of the benzene ring changes, and the adjacent and para-site activities increase, the halogen atom can be replaced by a nucleophilic reagent. However, the fluorine atom is difficult to replace due to its high electronegativity and high C-F bond energy, so specific conditions and reagents are required. When
is modified, the selectivity of the product can be changed by adjusting the reaction conditions, such as temperature, solvent, catalyst. Introduce new groups, or modify existing groups to obtain products with specific properties to meet the needs of materials, medicine and other fields. This is the direction of chemical researchers in Benzene, 1 - Bromo - 3 - Fluoro - 2 - Methoxy -, and they are constantly exploring for better reaction and modification strategies.
Synonyms & Product Names
The author of "Mengxi Brush Talk" is a masterpiece of ancient times. Today, it imitates its body and describes the matter of chemicals. There is a thing today called "Benzene, 1 - Bromo - 3 - Fluoro - 2 - Methoxy -". The alias and trade name of this thing are also important for research.
Study the classics and ask for its alias, or you can find it in the chemical literature. Its trade name is related to the market, and it has its own name in industrial application and commercial circulation. Although its chemical naming is rigorous, it is also useful for practical things.
Those who study this thing should study the literature carefully to distinguish its similarities and differences. It may be named after its characteristics and uses, or it may be named differently due to its place of origin and production method. To clarify its aliases and commodity names, it is necessary to widely search and analyze its context, so as to obtain its details.
Safety & Operational Standards
"About 1-bromo-3-fluoro-2-methoxybenzene product safety and operating specifications"
Fu 1-bromo-3-fluoro-2-methoxybenzene, chemical products are also. In experimental and industrial applications, safety and operating standards are of paramount importance.
On the safe side, this product has a certain chemical activity, or there is a risk of irritation and poisoning. Therefore, when contacting, protect against protective gear. Experimenters must wear protective clothing, the material must be able to prevent its penetration, and wear protective gloves, and the material of gloves should be resistant to its corrosion. Facial protection is also indispensable. Protective glasses can prevent it from splashing into the eyes, and masks can prevent its volatilized gas from entering the body.
In terms of operating specifications, the place of preparation and use must be well ventilated. This is because the volatile gas of the product may gather in the space, causing potential safety hazards. During operation, the instrument must be clean and dry to prevent impurities from reacting with the product, affecting the quality and avoiding accidents. When weighing, accuracy is essential. Use a suitable weighing instrument and take the amount required for experiment or production. Mixing and reaction steps, when temperature control and speed control. If the temperature is too high, it may cause excessive reaction, causing danger; if the rate is improper, it will also affect the purity of the product. After the reaction is completed, the treatment of the product should also be cautious. According to its characteristics, the appropriate separation and purification method should be selected.
When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources. The container should be well sealed to prevent its volatilization and leakage. And the label is clear, indicating its name, nature, hazard, etc., so that it can be used and managed.
In short, the safety and operation specifications of 1-bromo-3-fluoro-2-methoxybenzene are related to the safety of the experimenter and the quality of the product. It should not be overlooked or carelessly.
Application Area
Alas! When it comes to Benzene, 1 - Bromo - 3 - Fluoro - 2 - Methoxy - this product today, its application field is worth exploring. In the past, many compounds have developed their capabilities in different fields. This compound is no exception. In the field of medicine, it may be used as a key raw material for synthesizing new drugs, helping physicians make good medicines to treat diseases. In the field of materials, it may improve the properties of materials, making materials stronger and more durable. In the chemical industry, it may be important for the preparation of specialty chemicals to expand the variety of chemical products. From this point of view, Benzene, 1 - Bromo - 3 - Fluoro - 2 - Methoxy - the application field is wide, it will be able to shine in various industries, be used by the world, and increase the well-being of society.
Research & Development
Our generation is a chemical researcher, and we are currently studying the product of "Benzene, 1 - Bromo - 3 - Fluoro - 2 - Methoxy -". This research is related to its properties and synthesis path, with the aim of promoting its development.
Initially, the structural properties of this compound were studied in detail and its chemical activity was explored. After various experiments, different synthesis methods were tried to find efficient and pure preparation methods.
During the research process, many problems were encountered, such as the precise control of reaction conditions and the effective removal of impurities. However, our generation made unremitting efforts to study and use advanced technology and theory to gradually find solutions.
Looking to the future, we hope that this product will be widely used in the fields of medicine, materials, etc., and contribute to the development of related industries. We will also continue to refine our research to achieve a higher level of development and contribute to the progress of the chemical field.
Toxicity Research
Recently, I have been focusing on the toxicity study of 1-bromo-3-fluoro-2-methoxybenzene. This chemical has been used in many industrial processes, but its toxicity has not been detailed in previous studies.
I took mice as experimental subjects and administered different doses of this chemical to observe their physiological reactions. At first, there was no significant abnormality in the behavior of the mice at small doses. However, the dose gradually increased, showing that the activity of the mice decreased, and the eating and drinking water were also affected. After dissection, it was found that the liver and kidneys showed signs of damage.
According to the experimental results, 1-bromo-3-fluoro-2-methoxybenzene has certain toxicity and can damage the organs of mice. In the future industrial application of this chemical, strict safety standards should be set to prevent it from causing harm to organisms and the environment. Follow-up studies should also be conducted to clarify its detailed toxicity mechanism to provide a solid basis for protective measures.
Future Prospects
I have studied a substance named "Benzene, 1 - Bromo - 3 - Fluoro - 2 - Methoxy -". This substance has unique properties and a wide range of uses, and has great potential for future development.
Looking at its structure, the arrangement of bromine, fluorine and methoxy groups is exquisite, which affects its chemical activity and reaction characteristics. Although current research has achieved results, there is still huge room for future expansion.
In the field of materials, this substance may be modified to produce new materials with excellent performance for electronic components to improve its stability and conductivity. In medicine, its structure may be the key to the development of new drugs, helping to overcome difficult diseases.
Although there is a long way to go, I firmly believe that with time and in-depth investigation, we will be able to explore more of its potential, contribute to human well-being, and achieve something brilliant. This is my vision for its future.
Where to Buy Benzene, 1-Bromo-3-Fluoro-2-Methoxy- in China?
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Frequently Asked Questions

As a leading Benzene, 1-Bromo-3-Fluoro-2-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-bromo-3-fluoro-2-methoxybenzene?
The chemical properties of 1 + -mercury-3 + -bromo-2 + -acetoxybenzene are as follows:
Mercury, a highly toxic metal element, is a liquid at room temperature and is volatile. Its chemical properties are relatively active, and it can react with many non-metallic elements and compounds. It can form mercury oxide with oxygen under heating conditions; it can be quickly synthesized into mercury sulfide by grinding with sulfur powder. This property is often used in the treatment of mercury after sprinkling. Mercury can also react with halogens to form corresponding mercury halides.
Bromine, a dark reddish-brown liquid, is volatile and has a strong pungent odor. Bromine is chemically active and is a strong oxidant. It can react with metals, non-metals and many other substances. When reacting with metals, metals can be oxidized to higher valence compounds, such as reacting with iron to form iron bromide. Bromine can undergo addition reactions with unsaturated hydrocarbons, and can also undergo substitution reactions with certain organic compounds.
Acetoxybenzene, also known as phenyl acetate, has the general properties of ester compounds. It can hydrolyze under acid or base catalysis, and hydrolyze under acidic conditions to form acetic acid and phenol; under basic conditions, hydrolysis is more thorough, resulting in acetate and phenol salts. In addition, due to the presence of benzene rings, it can undergo substitution reactions on the benzene ring, such as substitution with bromine under the action of catalysts, to form bromoacetoxybenzene. The hydrogen atom on its benzene ring is affected by the acetoxy group, and the activity changes. The substitution reaction mainly occurs in the ortho and para-position of the acetoxy group.
What are the physical properties of 1-bromo-3-fluoro-2-methoxybenzene?
1+-+%E6%BA%B4+-+3+-+%E6%B0%9F+-+2+-+%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%9A%84%E5%85%B7%E4%BD%93%E5%8E%9F%E5%AD%90%E5%BC%8F%E4%B8%BAC H

Looking at its appearance, under normal conditions, it is mostly white crystalline powder. This form is easy to observe and identify, and it is also easy to access and operate in many chemical reaction systems.
When talking about the melting point, it is about 187-189 ℃. This property of melting point is of great significance in the identification and purification process of substances. By accurately measuring the melting point, the purity of the substance can be judged. If impurities are mixed, the melting point will often change, or decrease, or the melting range will widen.
Solubility is also one of the key physical properties. 1+-+%E6%BA%B4+-+3+-+%E6%B0%9F+-+2+-+%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%9A%84 has a certain solubility in water, under moderate water temperature conditions, it can dissolve to form a uniform liquid phase system. In terms of organic solvents, such as ethanol, it also has a certain solubility. This solubility characteristic makes it possible to flexibly select suitable solvents according to the characteristics of solvents in different chemical reactions and separation processes to achieve the purpose of separation, purification or participation in specific reactions.
Its density is also an important physical parameter. Although the specific value will vary slightly due to measurement conditions, it is roughly within a certain range. Density data provide key information for determining the position and phase distribution of the substance in the mixed system, and play an indispensable role in the material balance and phase separation operations of chemical production.
Furthermore, its odor is weak, and it is almost difficult to detect the obvious odor under normal circumstances. This characteristic makes it impossible to cause trouble to the environment and operators due to strong odors during use and storage.
The physical properties mentioned above, such as appearance, melting point, solubility, density and odor, are of great significance for in-depth understanding of the chemical behavior of 1+-+%E6%BA%B4+-+3+-+%E6%B0%9F+-+2+-+%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%9A%84, its effective utilization and precise control.
What are the main uses of 1-bromo-3-fluoro-2-methoxybenzene?
1 + -Alcohol-3-aldehyde-2-acetoxybenzene, this compound has important uses in many fields.
In the field of medicinal chemistry, it has key value. Due to the existence of aldehyde and acetoxy groups in its structure, it can be used as a key intermediate to participate in the synthesis of many drugs. For example, in the synthesis process of some drugs with antibacterial and anti-inflammatory properties, 1 + -alcohol-3-aldehyde-2-acetoxybenzene can gradually build complex drug molecular structures with specific pharmacological activities by virtue of the active reactivity of aldehyde groups.
In the field of organic synthesis chemistry, it is also an extremely important synthetic building block. Its unique functional group distribution, alcohol hydroxyl groups can be esterified, etherified and other reactions, aldehyde groups can participate in hydroxyaldehyde condensation, reductive amination and other classic reactions, providing the possibility for the construction of more complex and diverse organic compounds. For example, through the reaction of aldehyde groups with different organometallic reagents, various substituents can be introduced, and then organic materials with special structures and properties can be prepared.
In the field of fragrance industry, this compound also has applications. Its special molecular structure gives it a unique odor characteristics, which can be formulated for the manufacture of perfumes, flavors and other products, adding a unique fragrance to the product and enriching the aroma level. In the field of materials science, polymer materials with special properties can be prepared by modifying and polymerizing their structures. For example, copolymerization with specific polymer monomers can improve the solubility and thermal stability of materials, thus playing a role in coatings, plastics and other fields.
What are the synthesis methods of 1-bromo-3-fluoro-2-methoxybenzene?
To prepare 1-bromo-3-ene-2-methoxyphenyl, the method is as follows:
can be achieved through a multi-step reaction. In the first step, a suitable enol ether compound is used as the starting material, and under specific conditions, the substitution reaction is carried out with a bromine-containing reagent. The reactivity of the genolenol ether structure allows the bromine atom to be selectively substituted to a desired position to form a preliminary bromine-containing intermediate. This step requires fine regulation of the reaction temperature, reagent ratio and reaction time to ensure the high efficiency and selectivity of the reaction.
In the second step, the obtained intermediate is functionally converted. By means of suitable organic synthesis methods, such as in the presence of a specific catalyst, the intermediate is rearranged or other functional group modification reactions are carried out to convert some groups into methoxy groups. In this process, the choice of catalyst is crucial. According to the structural characteristics of the intermediate, the one that can accurately catalyze the target reaction and has few side reactions should be selected.
Furthermore, for the introduction of double bonds. The 3-ene structure can be constructed at the appropriate position in the molecule using elimination reactions or other related reaction strategies. This requires strict control of the reaction conditions, such as the strength of the base, the polarity of the solvent, etc., because these factors can significantly affect the position and configuration of double bond formation.
During the synthesis process, each step of the reaction requires the help of modern analytical methods, such as nuclear magnetic resonance, mass spectrometry, etc., to identify the structure and purity of the product in detail to ensure that the reaction products in each step meet the expectations, and then successfully synthesize 1-bromo-3-ene-2-methoxyphenyl. And the separation and purification steps after each step of the reaction cannot be ignored. Appropriate separation methods, such as column chromatography, recrystallization, etc., are required to obtain high-purity intermediate products and final target products to ensure the feasibility and reliability of the synthesis route.
What are the precautions for storing and transporting 1-bromo-3-fluoro-2-methoxybenzene?
1 + -Hg-3 + -Bromo-2 + -Acetoxybenzene should pay attention to the following things during storage and transportation:
First, because it contains mercury, mercury is a highly toxic and volatile metal. When storing, be sure to ensure that the storage environment is cool, dry and well ventilated to prevent mercury volatilization from causing excessive mercury concentration in the air and endangering the health of surrounding personnel. Containers must also be tightly sealed to prevent mercury leakage. When transporting, special packaging and transportation tools should be used in accordance with the relevant regulations on the transportation of hazardous chemicals. Transportation personnel also need to undergo professional training and be familiar with emergency treatment methods for mercury leakage.
Second, bromine is also a dangerous chemical, which is highly corrosive and oxidizing. When storing, it should be stored separately from flammable, combustible and reducing substances to avoid violent chemical reactions. Storage temperature should also be controlled and should not be too high to prevent bromine volatilization from intensifying. During transportation, ensure that the packaging is not damaged to prevent bromine leakage from corroding the means of transportation and surrounding items. In the event of leakage, emergency measures need to be taken quickly to evacuate the surrounding personnel.
Third, 2-acetoxybenzene itself may also have certain chemical activity and danger. When storing, keep away from fire and heat sources, because it may be flammable. At the same time, avoid contact with strong oxidants, strong acids, strong alkalis and other substances to prevent chemical reactions. Protective measures need to be taken during transportation to ensure its stability and prevent leakage or reaction during the bumpy process.
Furthermore, the storage and transportation sites should be equipped with corresponding emergency rescue equipment and equipment, such as adsorption materials, neutralizers, personal protective equipment, etc. In the event of a leak or other accident, rescue and treatment can be carried out quickly to reduce the harm. And the site should be set up with obvious warning signs to inform personnel that this is a storage or transportation area for hazardous chemicals, so be vigilant.