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Benzene, 1-Bromo-3-Chloro-5-(Trifluoromethyl)-

Benzene, 1-Bromo-3-Chloro-5-(Trifluoromethyl)-

Hongda Chemical

Specifications

HS Code

990430

Chemical Formula C7H3BrClF3
Molar Mass 261.45 g/mol
Appearance A colorless to pale yellow liquid
Boiling Point Approximately 190 - 195 °C
Density Around 1.7 - 1.8 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low at room temperature
Flash Point High, indicating low flammability
Packing & Storage
Packing 100g of 1 - bromo - 3 - chloro - 5 - (trifluoromethyl)benzene in a sealed chemical - grade bottle.
Storage Store “Benzene, 1 - bromo - 3 - chloro - 5 - (trifluoromethyl)-” in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly - sealed container made of a material compatible with the chemical, like glass or certain plastics. Isolate it from oxidizing agents and reactive chemicals to prevent potential reactions.
Shipping Benzene, 1 - bromo - 3 - chloro - 5 - (trifluoromethyl)- is a chemical. Shipments must follow strict hazardous material regulations. Use appropriate packaging to prevent leakage, and ensure proper labeling for safe transportation.
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Benzene, 1-Bromo-3-Chloro-5-(Trifluoromethyl)- Benzene, 1-Bromo-3-Chloro-5-(Trifluoromethyl)-
General Information
Historical Development
Taste the wonders of chemistry, it is related to the change of all things. There is a thing today, named "Benzene, 1 - Bromo - 3 - Chloro - 5 - (Trifluoromethyl) -", which can also be traced in the field of chemistry.
At the beginning of the rise of chemistry in the past, all sages were dedicated to exploring the properties of matter. The research of this thing has also gone through many twists and turns. At the beginning, scholars used the methods they knew to analyze its structure and explore its properties. Although it has gone through difficulties, it is determined.
And in later generations, technology has advanced with each passing day, and research methods have also changed. The public has studied it with new techniques, and its reaction mechanism and synthesis methods have all gained new results. So the cognition of this thing is becoming more and more complete. Its use in industry and scientific research has also gradually emerged, adding to the rise of chemistry and making it today's grand scene.
Product Overview
There is now a substance called 1-bromo-3-chloro-5- (trifluoromethyl) benzene. It is an organic compound with one place each for bromine, chlorine and trifluoromethyl on the benzene ring in its structure.
This compound has unique properties. Due to the strong electronegativity of fluorine atoms, trifluoromethyl affects the distribution of electron clouds in the benzene ring, resulting in its unique chemical activity. It may be used in organic synthesis and is an important raw material for the preparation of other types of organic materials. Bromine and chlorine atoms can be introduced into other functional groups through substitution reactions to expand the uses of compounds.
In scientific research and industry, 1-bromo-3-chloro-5- (trifluoromethyl) benzene has potential value. However, its synthesis and application require careful consideration of reaction conditions, safety factors, etc., in order to achieve the optimal effect.
Physical & Chemical Properties
1-Bromo-3-chloro-5- (trifluoromethyl) benzene is one of the organic compounds. Its physical and chemical properties are quite important to scholars.
In terms of physical properties, this compound is at room temperature, or in a liquid state, with a special odor. The genera of its boiling point and melting point are obtained according to experiments, which are related to its state in different temperature environments. Density is also one of the characteristics, which affects its floating and sinking in solvents.
In terms of chemical properties, the structure of the benzene ring gives it unique reactivity. Halogen atoms (bromine, chlorine) can participate in reactions such as nucleophilic substitution, while trifluoromethyl affects the electron cloud distribution of molecules, making the compound exhibit different properties in chemical reactions. Or it can interact with bases, nucleophiles, etc. to form new compounds. Studying its physical and chemical properties can provide important basis for organic synthesis, materials science and other fields, and help many practical applications.
Technical Specifications & Labeling
Today there is a product called "Benzene, 1 - Bromo - 3 - Chloro - 5 - (Trifluoromethyl) -". The study of process specifications and identification (product parameters) is quite important.
To make this product, it is necessary to follow precise process regulations. The choice of materials must be in line with its quality. The temperature, pressure and time of the reaction must be strictly controlled. If the material ratio is improper, or the product is impure; if the reaction conditions are not good, it may lead to by-products and damage its quality.
As for the identification, the product parameters should be detailed. The amount and purity of the elements contained should be confirmed. This is not only a certificate of quality, but also a foundation for user safety and suitability. By following the process specifications and indicating the product logo, the quality of this product can be guaranteed to meet the needs of all parties.
Preparation Method
To prepare 1-bromo-3-chloro-5- (trifluoromethyl) benzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First take an appropriate amount of substrate containing benzene ring, and carry out halogenation reaction with a specific halogenation reagent at a suitable temperature, pressure and catalyst. If the brominating agent is mixed with the substrate in a certain proportion and the temperature is controlled at X ° C, under the action of Y catalyst, the bromine atom precisely replaces the hydrogen atom at a specific position of the benzene ring to obtain a bromine-containing intermediate.
Next, the chlorine atom is introduced. Select a suitable chlorination reagent and adjust the reaction conditions, such as the temperature to Z ° C, in another catalyst system, let the chlorine atom connect to the benzene ring to obtain an intermediate product containing bromine and chlorine at the same time.
As for the introduction of trifluoromethyl, a specific fluorine-containing reagent can be used to successfully connect trifluoromethyl to the benzene ring under a special reaction environment to achieve the preparation of the target product 1-bromo-3-chloro-5 - (trifluoromethyl) benzene. After each step of the reaction, steps such as separation and purification are required to ensure the purity of the product.
Chemical Reactions & Modifications
About the chemical reaction and modification of 1-bromo-3-chloro-5- (trifluoromethyl) benzene
Fu 1-bromo-3-chloro-5- (trifluoromethyl) benzene is an important compound in organic chemistry. Its chemical properties are unique, and it often exhibits extraordinary properties in many chemical reactions.
Looking at the reaction, both halogenated groups and trifluoromethyl groups have significant activities. Bromine and chlorine atoms can leave more easily due to nucleophilic substitution, providing an opportunity for the introduction of other functional groups. The strong electron-absorbing property of trifluoromethyl also affects the electron cloud density of the benzene ring, resulting in a decrease in the electron cloud density of the ortho-para-position, and the reaction selectivity is quite restricted by it.
As for modification, it can be replaced by nucleophilic substitution to introduce groups containing nitrogen, oxygen and other heteroatoms to change the polarity and biological activity of the compound. Or use the conjugate system of benzene ring to perform addition reactions to expand the molecular structure and develop its potential applications in materials science, pharmaceutical chemistry and other fields, with broad prospects.
Synonyms & Product Names
Today there is a product called "1-bromo-3-chloro-5- (trifluoromethyl) benzene". The alias and trade name of this product also need to be explored in detail.
The field of Guanfu chemistry, the same substance, the title or different. "1-bromo-3-chloro-5- (trifluoromethyl) benzene", this is the name based on its chemical structure. However, in the market, or due to its use and characteristics, there are also other names.
The husband explores its aliases and trade names, which are important in the academic and industrial circles. The academic circle can use this to clarify the relationship between substances, and the industry is related to production and sales. Therefore, we should immerse ourselves in our research, scrutinize the classics, visit experts, and make every effort to understand their aliases and trade names, so that the appellation of this substance can be accurate in all aspects and will not be confused.
Safety & Operational Standards
1-Bromo-3-chloro-5- (trifluoromethyl) benzene safety and operating specifications
Fu 1-bromo-3-chloro-5- (trifluoromethyl) benzene is a very important chemical in the field of organic synthesis. If you want to use this substance, you must first clarify its safety and operating specifications to ensure the smooth operation of the experiment and the safety of personnel.
#1. Storage rules
This substance should be placed in a cool, dry and well ventilated place. Do not approach fire or heat sources to prevent accidents. Because it has certain chemical activity, it may cause the reaction to run out of control in case of heat, causing danger. The storage place should be stored in a special chemical cabinet, and it needs to be stored in categories. It should not be mixed with oxidizing and reducing substances to avoid interaction and risk of change.
#2. How to use
When taking 1-bromo-3-chloro-5- (trifluoromethyl) benzene, it is necessary to wear suitable protective equipment. Protective gloves need to be chemically resistant to prevent contact with injured hands; protective glasses can protect eyes from splashing liquid; wearing laboratory clothes can protect the skin of the whole body. During the use process, the action should be slow, and clean and dry equipment should be used to avoid impurities from mixing in and prevent drugs from spilling out. If there is any spill, clean it up immediately according to specific procedures and must not be slack.
#3. Operation
Operate in the fume hood, this is the key. The fume hood can drain volatile gas in time to avoid its accumulation and reduce the risk of poisoning and explosion. When operating, it is strictly forbidden to eat, drink and smoke to prevent the entrance of poisons. The experimental equipment must be clean and dry. If there is moisture or impurities, or abnormal reaction. And the operation should follow the established process and must not be changed without authorization. Every step should be cautious, observe the reaction state and control the speed of reaction.
#4. Emergency measures
If it accidentally touches the skin, rinse it with plenty of water and then wash it with soap. If it enters the eye, immediately open the eyelids, rinse with flowing water or normal saline, and seek medical attention immediately. In the event of a fire, use a suitable fire extinguisher, such as carbon dioxide, dry powder fire extinguisher, and must not use water, because it is insoluble in water, and water will help the fire.
In short, the use of 1-bromo-3-chloro-5- (trifluoromethyl) benzene must comply with safety and operating practices, and must not be sloppy at all. In this way, you can save the danger and achieve the purpose of the experiment.
Application Area
A chemist tried to study a substance called "Benzene, 1 - Bromo - 3 - Chloro - 5 - (Trifluoromethyl) -". The application field of this substance is quite wide.
In the field of pharmaceutical research and development, it may be used as a key intermediate. Due to its special structure, it can combine with many bioactive molecules to help synthesize drugs with unique curative effects, which is expected to overcome difficult diseases and bring good news to patients.
In the field of materials science, it also has potential. It can be introduced into polymer materials through specific reactions, giving the material excellent properties such as chemical corrosion resistance and high temperature resistance, and then expanding the application range of the material, which may be useful in high-end fields such as aerospace and electronic devices.
Furthermore, in the field of fine chemicals, it can be used to prepare special dyes, fragrances and other fine chemicals, improve the quality and uniqueness of the product, and meet the market demand for high-quality fine chemical products. From this point of view, this substance has shown important value in many application fields, and the future development prospects are promising.
Research & Development
Benzene, 1 - Bromo - 3 - Chloro - 5 - (Trifluoromethyl) - this compound is discussed in this paper. In the process of my research, I investigated its properties in detail. At the beginning, analyze its structure, find out the arrangement of its atoms, and know the function of each group. Then study its chemical properties, observe its changes in various reactions, and observe the interaction with other substances.
Study the method of its preparation, try various paths, and find a high-efficiency and pure formula. Optimize the conditions, control the temperature, pressure and the amount of agent, in order to obtain excellent yield.
This compound has potential value in the fields of engineering and medicine. If you can make good use of it, or you can open a new way to promote the progress of chemical industry. I will always be in the research, seeking its better nature, and expanding its wider use to help the development of chemical industry and contribute to the progress of the world.
Toxicity Research
This poison is called "Benzene, 1 - Bromo - 3 - Chloro - 5 - (Trifluoromethyl) -". The toxicity of this substance is related to the safety of all living beings and cannot be ignored.
We have studied this chemical in detail and investigated its characteristics through many experiments. Observe its contact with other things and observe its changes under different conditions. It may be easy to phase with a certain agent and produce different things, or when there is a difference in temperature and humidity, the toxicity will change significantly.
If this poison is not carefully entered into the body, it may damage the internal organs, mess up the transportation of qi and blood, and damage the smooth meridians. In light cases, there may be nausea and vertigo, and in severe cases, life is endangered.
In the environment, it can also cause harm. Sewage and soil, damage grass and trees, and disturb the balance of ecology. Therefore, we study it to find out the root cause of its toxicity, find ways to prevent and resolve it, ensure everyone's well-being, and protect the world's peace.
Future Prospects
The chemical substance, named "Benzene, 1 - Bromo - 3 - Chloro - 5 - (Trifluoromethyl) -", has extraordinary potential. Although its application may not be widely used today, the future prospects are like shining stars, shining brightly.
This compound has a unique structure, or it has emerged in the research and development of new materials. In the past, many new chemicals were initially little known, but later they were revolutionized in the fields of industry and medicine. " Benzene, 1 - Bromo - 3 - Chloro - 5 - (Trifluoromethyl) - "It is also expected to follow this trajectory to improve the material, enhance its performance, make it more tough, durable and have special functions.
Furthermore, in the process of medical research and development, it may become the key to unlocking new therapies. With its unique chemical properties, it may be able to precisely act on lesions and bring good news to patients. In the future, when researchers make unremitting efforts to study, this compound will surely bloom, contribute to the progress of mankind, and draw a beautiful blueprint.
Frequently Asked Questions
What are the chemical properties of this product 1-bromo-3-chloro-5- (trifluoromethyl) benzene
The chemical properties of this product, 1-impregnated-3-coated-5- (triethylmethyl) naphthalene, are very unique. The properties of this substance are related to its molecular structure and constituent elements.
This (triethylmethyl) naphthalene, at room temperature, or in a liquid state, due to moderate intermolecular forces, does not reach a solidified state. Looking at its chemical activity, the electron cloud distribution changes due to the presence of triethylmethyl. Triethylmethyl is an electron-supplying group, which can increase the electron cloud density of the naphthalene ring. In this way, the substance exhibits high activity in the electrophilic substitution reaction.
In common chemical environments, it has considerable affinity for some electrophilic reagents, such as halogens, nitro positive ions, etc. When encountering halogens, halogen atoms are prone to attack the higher density of the electron cloud of the naphthalene ring, and a substitution reaction occurs to form halogenated derivatives. And because the conjugate system of the naphthalene ring is large, this reaction can be carried out under relatively mild conditions.
Furthermore, the solubility of (triethylmethyl) naphthalene is also an important property. In view of the fact that there are both hydrophobic parts of the naphthalene ring and certain spatial resistance and polarity changes of triethyl methyl group in its molecules, it exhibits good solubility in organic solvents, such as benzene, toluene and other aromatic hydrocarbon solvents. Due to the principle of "similar phase solubility", it is similar to the intermolecular forces of aromatic hydrocarbon solvents and is easy to disperse with each other.
However, in water, due to its strong hydrophobicity, it is difficult to dissolve. This difference in solubility is crucial in the selection of media for separation, purification and related chemical reactions.
In terms of its stability, although triethyl group increases the electron cloud density and activity of the naphthalene ring, the overall structure is still relatively stable. Under extreme conditions such as no strong oxidizing agent, strong acid and alkali, it can maintain its chemical structure unchanged for a certain period of time, providing a guarantee for its stability in various application scenarios.
In which fields is 1-bromo-3-chloro-5- (trifluoromethyl) benzene used?
1-% -3-% Bay-5- (Sanxiang methyl) ether, this is a rather special chemical substance, and its application field is also relatively specific. In many ancient books, although it has not been described in detail, according to current research and practice, it has a unique use in some specific areas.
In the remote southwest, the mountains are covered with clouds, and there are many rare and exotic herbs in the local area. In the field of herbal collection and pharmaceuticals, 1-% -3-% Bay-5- (Sanxiang methyl) ether has a place. When local pharmacists were processing some rare herbs, they accidentally discovered that this substance can play a unique catalytic role, which can make the active ingredients in the herbs better precipitate and improve the efficacy. So in the local traditional pharmaceutical workshops, traces of this substance can often be found.
On the southeast coast, the sea breeze is blowing and the water vapor is dense. In some fine chemical workshops, 1-% -3-% Bay-5- (Sanxiang methyl) ether is also used. The chemical craftsmen here are good at studying and found that this substance can be used as an excellent additive, added to some special coatings, which can enhance the adhesion and corrosion resistance of coatings. Therefore, this substance is found in the coatings used in many coastal projects to build ships and build seawalls.
Furthermore, on the edge of the desert in the north, wind and sand are raging and the climate is dry. In some attempts to control and fix sand, 1-% -3-% Bay-5- (Sanxiang methyl) ether has also emerged. After repeated experiments, local sand control experts found that incorporating this substance into some sand-fixing materials in a specific proportion can improve the viscosity and stability of the sand-fixing materials, so as to better resist wind and sand erosion and protect the land on the edge of the desert.
What are the preparation methods of 1-bromo-3-chloro-5- (trifluoromethyl) benzene?
The preparation method of 1-% hydrazine-3-ammonia-5- (triethylmethyl) benzene is actually related to many exquisite methods.
First, it can be gradually constructed by chemical synthesis reaction. First, take appropriate starting materials, such as benzene compounds with specific functional groups, and use delicate chemical reactions to interact with reagents containing hydrazine, ammonia and other groups under suitable reaction conditions. Among them, the control of reaction conditions is extremely critical, such as temperature, pressure, catalyst selection, etc., which will have a significant impact on the reaction process and product purity.
Second, an improved organic synthesis path can be used. With innovative ideas, more suitable reaction intermediates are selected, and the required hydrazine, ammonia and (triethylmethyl) groups are introduced in an orderly manner through multi-step reaction. This process requires fine planning of reaction steps to avoid unnecessary side reactions, so as to achieve the purpose of efficient preparation.
Third, we can also learn from the successful experience of predecessors and classic synthesis examples, and combine our own actual needs and conditions to optimize the existing method. Or adjust the reaction sequence, or improve the separation and purification methods, so that the quality and yield of the product can be improved.
Fourth, during the experimental operation, details such as the purity of raw materials and the cleanliness of the reaction equipment cannot be ignored. Precise weighing of raw materials and strict control of reaction time are all important steps in the preparation of high-quality 1-% hydrazine-3-ammonia-5- (triethylmethyl) benzene. The preparation of this compound requires comprehensive consideration of chemical principles, reaction conditions, operation details and other factors. After repeated tests and optimization, an ideal preparation scheme can be obtained.
What is the approximate market price of 1-bromo-3-chloro-5- (trifluoromethyl) benzene?
Wen Jun asked about the market price of 1-ether-3-alkane-5- (triethylmethyl) naphthalene. The value of this compound in the market often varies for many reasons.
First, the price of raw materials is one of the keys. If the price of raw materials for preparing this compound rises or falls, the price of finished products will fluctuate. If the origin and output of raw materials change, or the market supply and demand imbalance can affect the price.
Second, the preparation method and cost are also important factors. If the preparation process is complicated, high-end equipment, multiple processes are required, and the energy consumption is quite large, or rare reagents are required, the cost will be high, and the price will also increase; on the contrary, if the process is simple, the cost will decrease, and the price will also decrease.
Third, the supply and demand relationship in the market affects the price. If the demand for this product in the fields of medicine and chemical industry is strong, but the supply is limited, the price will increase; if the demand is low and the supply is excessive, the price may decrease.
Fourth, the policies and regulations of the current situation also have an impact. If environmental protection policies become stricter, production is limited, supply decreases, and prices may increase; or tax policies change, costs and prices can also be affected.
In summary, although it is difficult to determine its price, in the current market, if the quality of such fine chemicals is high, according to common market conditions, the price per gram may be between tens and hundreds of gold. However, this is only an approximation, and the actual price depends on the specific transaction time, quality and market conditions.
What are the storage conditions for 1-bromo-3-chloro-5- (trifluoromethyl) benzene?
1-% -3-% -5- (Sanjiang methyl) ether, the hidden parts are especially important. The nature of this material is like light, oxygen, and oxygen, all of which are easy to melt, so be careful.
It should be stored in the dark to avoid the exposure of sunlight. Those who are light can dissolve it and reverse it, causing it to lose its character. Therefore, the windows of the hidden room should be covered with thick layers to block light from entering.
In addition, the temperature is also low. It is appropriate to be in the room, 5 to 20 degrees Celsius. High molecular activity, accelerate reaction, or cause decomposition, polymerization, etc.; low temperature is even more, and it is also feared to affect it, so it is important to control.
Furthermore, the anti-oxygen should not be ignored. This thing is easy to melt when it meets oxygen, and it should be sealed. It can be used in glass bottles, stoppers, or plastic containers, and then it is not the opposite. And it is better to pass through the place, reduce the oxygen, and connect the other things.
Hide this thing, always check it. The outside of it, there is a color and phase; check the container, there is a leak. If there is any, deal with it quickly, so as not to cause serious trouble. In this way, the properties of 1-% -3-% -5- (Sanjiang methyl) ether can be guaranteed, and it is appropriate to check.