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Benzene, 1-Bromo-2-Fluoro-4-Methoxy-

Benzene, 1-Bromo-2-Fluoro-4-Methoxy-

Hongda Chemical

Specifications

HS Code

377900

Chemical Formula C7H6BrFO
Molecular Weight 205.024

As an accredited Benzene, 1-Bromo-2-Fluoro-4-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 1 - bromo - 2 - fluoro - 4 - methoxy - benzene in sealed chemical - grade vial.
Storage 1 - Bromo - 2 - fluoro - 4 - methoxy - benzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store separately from oxidizing agents, acids, and bases to prevent chemical reactions. Label the storage clearly for easy identification and safety.
Shipping Benzene, 1 - bromo - 2 - fluoro - 4 - methoxy - should be shipped in accordance with hazardous chemical regulations. Use appropriate, well - sealed containers to prevent leakage during transit, ensuring safe transportation.
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Benzene, 1-Bromo-2-Fluoro-4-Methoxy- Benzene, 1-Bromo-2-Fluoro-4-Methoxy-
General Information
Historical Development
In the field of chemistry, there is a name called 1-bromo-2-fluoro-4-methoxybenzene. Its initial exploration is like a secret of a veil. In the past, chemical masters searched for complex substances, and this compound was just beginning to emerge.
At that time, the experimental method was still simple, and the materials were also limited. However, with the tenacity of the public, they worked tirelessly to explore its characteristics. With the passage of time, the technology has become more and more exquisite, and the understanding of 1-bromo-2-fluoro-4-methoxybenzene has gradually increased. From the preliminary structure analysis to the clarification of its reaction mechanism, every step has been soaked in the efforts of the wise.
Over the years, this compound has emerged in the field of organic synthesis and is widely used. Its development process is like a long scroll, drawn by the efforts of countless chemists, and the road ahead is expected to be even brighter.
Product Overview
Today there is a substance called 1-bromo-2-fluoro-4-methoxybenzene. Its shape may be colorless to pale yellow liquid, with unique chemical properties. This compound, on the benzene ring, has bromine, fluorine and methoxy groups on each side, and affects each other to create different properties.
In the field of organic synthesis, 1-bromo-2-fluoro-4-methoxybenzene is often a key raw material. Bromine atoms are active and can participate in many nucleophilic substitution reactions, introducing various functional groups; the presence of fluorine atoms enhances molecular stability and fat solubility; methoxy groups have an impact on the distribution of electron clouds in the benzene ring, affecting the reaction activity and selectivity.
Through a specific chemical reaction path, chemists can borrow 1-bromo-2-fluoro-4-methoxybenzene to prepare a variety of bioactive compounds, which have potential application value in the research and development of medicine and pesticides.
Physical & Chemical Properties
The physicochemical properties of 1-bromo-2-fluoro-4-methoxybenzene are related to our chemical research. The color state of this compound is usually a colorless to light yellow liquid with a specific odor. Its boiling point is about a certain value, which varies slightly due to different pressures, which is related to the size of the intermolecular force. The melting point also has its own inherent value, reflecting the change of molecular arrangement.
In terms of solubility, it has a certain solubility in organic solvents such as ethanol and ether. This is based on the principle of similar compatibility, because the polarity of its molecular structure is similar to that of organic solvents. However, the solubility in water is very small, because its non-polar part accounts for a large proportion.
In addition, its chemical properties are also worth noting. The presence of benzene rings makes them aromatic, and electrophilic substitution reactions can occur, such as halogenation and nitrification. The substitution of bromine, fluorine and methoxy groups also affects the electron cloud density of benzene rings, and the reactivity is slightly different from that of benzene. These various properties are the cornerstones for us to deeply understand this compound and explore its applications.
Technical Specifications & Labeling
Today there is a product called 1-bromo-2-fluoro-4-methoxybenzene (Benzene, 1-Bromo-2-Fluoro-4-Methoxy -). Its technical specifications and identification (commodity parameters) are the key.
In terms of its technical specifications, it is necessary to synthesize it in a precise way. The selection of raw materials must be pure, and the reaction conditions should be strictly controlled. Temperature, pressure, and reaction time are all fixed, and there should be no difference in the pool. If the reaction equipment is used, it must be clean and suitable to prevent impurities from mixing and damaging its quality.
As for the label (product parameters), the appearance, color, purity, etc. of the product should be clearly marked. When its purity reaches a specific standard, the impurity content must be strictly limited. And on the package, the name, chemical formula, molecular weight and other key information should be clearly identifiable so that it can be recognized and used. In this way, the quality and safety of this product can be guaranteed, and it can be suitable for all purposes.
Preparation Method
To prepare 1-bromo-2-fluoro-4-methoxybenzene (Benzene, 1-Bromo-2-Fluoro-4-Methoxy -), the raw materials and production process are the key. An appropriate amount of p-methoxyphenol can be taken first and used as the starting material. In a suitable reaction vessel, under the condition of low temperature and the presence of a catalyst, a fluorine-containing reagent is slowly added dropwise, and the phenolic hydroxyl ortho-site is introduced into the fluorine atom through nucleophilic substitution reaction.
Then, the temperature of the reaction system is slightly increased, and a specific brominating reagent, such as copper bromide, is added to control the reaction process, so that the bromine atom selectively replaces the hydrogen of the fluorine atom, and then the target product is obtained. In this process, the reaction conditions need to be carefully controlled, such as temperature, reactant ratio and reaction time, which will affect the yield and purity of the product. The choice of catalyst cannot be ignored, and it needs to be able to promote the reaction efficiently and minimize the occurrence of side reactions. In this way, an ideal 1-bromo-2-fluoro-4-methoxybenzene can be obtained.
Chemical Reactions & Modifications
The chemical reaction and modification of 1-bromo-2-fluoro-4-methoxylbenzene are very important in the study of benzene compounds today. In the field of chemistry, explore its reaction path, which can explain its property transformation, and then obtain better products.
1-bromo-2-fluoro-4-methoxylbenzene has a unique structure, and the resistance and electronic effect of bromine, fluorine and methoxy groups have a great influence on its reactivity. Through nucleophilic substitution, its substituent can be changed and its chemical properties can be adjusted. If the appropriate nucleophilic reagent is encountered, the bromine atom can be replaced to obtain a new derivative.
When modifying, the reaction conditions need to be considered. Temperature, solvent, and catalyst are all related to the reaction effect. Precise control can improve the purity and yield of the product. The chemical modification of this compound paves the way for the synthesis of novel functional materials, and may have extraordinary application prospects in the fields of medicine and materials.
Synonyms & Product Names
In the benzene family, there is a thing called 1-bromo-2-fluoro-4-methoxybenzene. The alias and trade name of this thing are also valued by researchers. Husband aliases, so different from the common name, so that the same thing and the different name, all belong to. The trade name is related to the easy circulation of the city, and it is also the logo of the goods.
1-bromo-2-fluoro-4-methoxybenzene, with its chemical quality, may have different names. This is because of the research of scholars, different angles, and different naming methods. As for the name of the product, the merchant established this name in order to recognize the characteristics of the product, or to facilitate the sale of the product. Although the two are different, they both refer to the same chemical product. In the field of chemical research, knowing its alias and trade name can make it possible to observe the physical properties and clarify its use. Whether it is for experiments or for production, it depends on the certainty of this name.
Safety & Operational Standards
About 1-bromo-2-fluoro-4-methoxybenzene product safety and operating specifications
1-bromo-2-fluoro-4-methoxybenzene, this substance is occasionally involved in chemical research, and its safety and operating standards must not be ignored.
The first thing to do with safety is protection. When coming into contact with this substance, special protective clothing is required to prevent its possible erosion. Hands must wear chemically resistant gloves to avoid contact with the skin and cause damage. Eyes also need protection, and protective blindfolds are essential to prevent it from splashing in and damaging the eyes.
When operating, ventilate well. Place this chemical in a fume hood for operation, so that the volatile gas can be quickly discharged outdoors, avoiding the risk of poisoning in the room. And the place of operation, when away from fire and heat sources, because it may be flammable, in case of open flames, hot topics, fear of fire and explosion.
When storing, there are also regulations. It should be stored in a cool, dry and ventilated place, protected from light and cool, to prevent deterioration. And it must be separated from oxidants, acids and alkalis, so as not to react with each other and cause accidents.
When taking it, the action should be slow and careful. Measure it with special equipment, operate it accurately, and do not spill it. If there is any spill, dispose of it quickly according to the specifications. Small amounts can be absorbed by inert materials such as sand and vermiculite; large amounts can be collected by containment and handed over to professional institutions for disposal.
When discarded, it cannot be discarded at will. According to relevant regulations, hand it over to a qualified treatment unit and dispose of it according to regulations to ensure environmental safety.
This is the standard for the safety and operation of 1-bromo-2-fluoro-4-methoxybenzene. Chemical researchers must not abide by it to ensure their own safety and protect the environment.
Application Area
"Benzene, 1-bromo-2-fluoro-4-methoxy-application field"
Fubenzene derivatives, 1-bromo-2-fluoro-4-methoxy-are useful in various fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs. Due to its unique structure, it can precisely combine with specific targets in organisms, which is expected to lead to new therapeutic agents and cure difficult diseases.
In materials science, it is also of great value. It can be integrated into the polymer material system through specific reactions to improve the properties of the material, such as enhancing its stability and improving its optical properties, which contribute to the creation of high-performance new materials.
In the field of organic synthetic chemistry, this compound can participate in a variety of reactions, and use its functional group characteristics to construct complex organic molecular structures, expand the boundaries of organic synthesis, and contribute a lot to the development of organic chemistry.
Research & Development
I have been dedicated to the research of chemical substances for a long time, and now I focus on the substance "Benzene, 1 - Bromo - 2 - Fluoro - 4 - Methoxy -". After long-term research, we have a deep understanding of its research and development path, which is full of difficulties and opportunities.
In the process of exploration, we analyze its molecular structure, gain insight into its chemical properties, and strive to clarify its reaction mechanism under different conditions. This substance may have potential application value in many fields, but in order to convert it into practical use, we still need to overcome many difficulties.
Our researchers maintain perseverance and keep trying new methods and technologies, hoping to promote its theoretical research to practical application. Although we are currently facing numerous challenges, we firmly believe that through unremitting efforts, we will be able to make breakthroughs in the research and development of "Benzene, 1 - Bromo - 2 - Fluoro - 4 - Methoxy -" and contribute to the progress of related fields.
Toxicity Research
The current study of this substance is called "Benzene, 1 - Bromo - 2 - Fluoro - 4 - Methoxy -", and we will investigate its toxicity in detail. The nature of this substance, or the harm involved, cannot be ignored in the human body or in the surrounding environment.
To understand its toxicity, multiple methods are required. Observe its chemical structure, analyze its reaction state, and observe its changes in living organisms. Based on experiments, use various organisms as tests to observe the effects of this substance, such as growth state and physiological ability.
It also examines its distribution in the environment, changes in water, soil, and air, and the impact. Study the degradation rules of this substance and the properties of its degradation products.
The study of toxicity is not a one-day effort, and it is necessary to be cautious and accurate in order to ensure the ecological safety of everyone.
Future Prospects
In the field of chemical research, its unique characteristics may serve as the cornerstone of many new synthetic pathways. The exploration of the properties of this compound, or the introduction of innovative synthetic methods, may lead to the development of new anti-chemical pathways.
In the field of materials science, or due to its own special functional combination, it can be used to develop the power of materials for specific functional materials. Or it can be used to develop high-performance materials, or to improve the new optical properties of optical materials. Furthermore, in the field of physical and chemical engineering, it may provide a sense of sensitivity for new research and development, and serve as the core skeleton of active ingredients. It is expected to produce products with excellent efficacy for specific diseases. Therefore, 1-bromo-2-fluoro-4-methoxybenzene is not yet available, and the possibility of filling it is limited. It is up to our researchers to explore it in depth to reveal its secrets and benefit the world.
Where to Buy Benzene, 1-Bromo-2-Fluoro-4-Methoxy- in China?
As a trusted Benzene, 1-Bromo-2-Fluoro-4-Methoxy- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzene, 1-Bromo-2-Fluoro-4-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-bromo-2-fluoro-4-methoxybenzene?
1 + - + Mercury + - + 2 + - + River + - + 4 + - + Methoxy Phenyl. This is to explore the properties of mercury and compounds containing methoxy phenyl groups. Mercury is the only gold element that is often in liquid form. With its diversity, mercury can form alloys with more gold, and this alloy is mercury. Mercury can also be reacted with oxygen, and when added, mercury can be oxidized to form mercury oxide.
And the meaning of 2-river, if the matter involved in the river environment is understood, mercury will be reformed in this environment. Mercury can degrade methylmercury under the action of microorganisms. Methylmercury is toxic and easy to accumulate in organisms, causing serious harm along food and organisms.
to 4-methoxy phenyl, this function can affect the specificity of compounds. The presence of methoxy groups affects the cloud density of benzene, making it easier to generate benzene. For example, under suitable conditions, other groups can be introduced into benzene. The supply of methoxy groups increases the density of benzene clouds, making them more reactive with benzene. It is often used in the synthesis of benzene molecules. Moreover, the chemical properties of mercury and methoxy phenyl compounds are rich, and different reaction characteristics are developed in different environments.
What are the applications of 1-bromo-2-fluoro-4-methoxybenzene in organic synthesis?
The common applications of 1 + -bromo-2-alkane-4-methoxyphenyl in organic synthesis are as follows:
First, in the nucleophilic substitution reaction, the bromine atom activity of this compound is quite good, and it can react with various nucleophilic reagents, such as alkoxides and amines. For example, the reaction of alkoxides with it can form corresponding ether products; the reaction of amines with it can prepare nitrogen-containing organic compounds. The key to this process lies in the nucleophilic properties of nucleophilic reagents and the precise control of reaction conditions, such as temperature and solvent selection.
Second, it also plays an important role in metal-catalyzed coupling reactions. Taking the coupling reaction catalyzed by palladium as an example, it can be coupled with aryl boronic acid, alkenyl halide, etc. under the action of palladium catalyst and ligand, thereby forming carbon-carbon bonds, which greatly enriches the structure of organic molecules. This reaction is of great significance for the construction of complex structures in organic synthesis, and can be used to prepare organic materials and pharmaceutical intermediates with specific structures and functions. During the reaction, factors such as the activity of the catalyst, the type of ligands, and the pH of the reaction system will all have a significant impact on the efficiency and selectivity of the reaction.
Third, the presence of methoxy groups can affect the electron cloud density of the benzene ring, thereby affecting the reaction activity and selectivity on the benzene ring. During the electrophilic substitution reaction on the benzene ring, the methoxy group acts as the power supply, which can increase the electron cloud density of the ortho and para-sites of the benzene ring, making the electrophilic substitution more likely to occur at these locations. In this way, through rational design of the reaction, other functional groups can be selectively introduced at specific positions of the benzene ring to achieve precise synthesis of the target compound.
Fourth, 1 + -bromo-2-alkane-4-methoxy phenyl can be used as a key starting material in the construction of complex ring structures. With the help of intramolecular reactions, such as cyclization reactions, compounds with specific ring structures can be constructed. By skillfully designing the molecular structure and reaction conditions, precise control of the size of the cyclic compound and the position of the substituent on the ring can be achieved, laying the foundation for the synthesis of natural products or drug molecules with unique structures and biological activities.
What is the preparation method of 1-bromo-2-fluoro-4-methoxybenzene?
To prepare 1-bromo-2-ene-4-acetoxybenzene, the ancient method may be as follows:
First take an appropriate amount of benzene, use the brominating agent bromine, and carry out the bromination reaction under the catalysis of a suitable catalyst such as iron filings. This process should pay attention to the reaction temperature and the drip rate of bromine to prevent excessive bromination. Bromobenzene can be obtained by reaction.
Then, the step of enylation of bromobenzene is applied. With a specific enylating agent, in a suitable alkali and organic solvent environment, after a multi-step reaction, the alkenyl group is introduced. This step requires precise control of the reaction conditions, including temperature, time, and the ratio of reagents, to ensure the smooth progress of the enylation reaction to obtain the bromobenzene derivative containing the enyl group.
Then, the acetoxy group is introduced. Select an acetylation reagent, such as acetic anhydride or acetyl chloride, and react with the bromobenzene derivative containing the enyl group in the presence of a catalyst. This reaction also requires careful regulation of the reaction conditions so that the acetoxy group can be accurately connected to the target position to obtain 1-bromo-2-ene-4-acetoxybenzene.
After the reaction is completed, it still needs to be separated and purified. Commonly used methods include distillation, recrystallization, column chromatography, etc., to remove impurities such as reagents and by-products remaining in the reaction to obtain pure 1-bromo-2-ene-4-acetoxybenzene.
These are all speculative ancient methods, for reference only, and the actual preparation may vary depending on time and place.
What are the physical properties of 1-bromo-2-fluoro-4-methoxybenzene?
1 + - mercury, 2 + - river, 4 + - methylbenzene, what is the physical reason?
Mercury, the common water, is the only liquid gold element under normal conditions. Its color is white, it has gold light, and it has good weight and fluidity. The melting temperature of mercury is low, -38.87 ° C, and the boiling temperature is not high, at 356.6 ° C. Its density is high, 13.59 g/cm ³. This characteristic makes mercury easy to settle in other liquids. Mercury has good performance, but its performance is weak. In addition, the surface force of mercury is large, and it is easy to form spherical droplets. It is insoluble in water and more soluble, but soluble in oxidizing acids such as nitric acid and aqua regia.
The river, a naturally formed channel, is the main flow form of surface water. River water is generally clear and transparent, but it also varies depending on the basin environment. Its density is nearly 1 g/cm ³, slightly lower than that of mercury. The melting temperature of river water is 0 ° C, and the boiling temperature is 100 ° C. This is the characteristic under normal conditions. The stability of river water is weak, but if the water contains many particles, such as water, water, water, etc., the stability increases. The flow rate of river water is affected by factors such as topography and climate, and the flow rate varies.
to 4 + -methyl benzene, which has chemical compounds. Under normal conditions, it is more solid or liquid. Its melting and boiling depend on the location of molecules and substituents. In general, the molecular weight of the phase is large, the molecular force is increased, and the boiling phase is increased. 4 + -methyl benzene has certain properties and can be slow in air. Its density is usually less than that of water, and it can float on the water surface. Its solubility is also special, and it can be soluble in partially soluble materials, such as ethanol, ether, etc., but its solubility in water is limited. Due to its presence, the solubility of water is poor.
What are the common reaction types of 1-bromo-2-fluoro-4-methoxybenzene?
In the ancient alchemy techniques of Huaxia, mercury (mercury), lead, dansa (mercury sulfide), methoxybenzene, etc. are all commonly used in alchemy, and their related reactions contain many ways.
Mercury has unique properties and often involves the following common reactions: First, it is an oxidation reaction. Under heating conditions, mercury can be fused with oxygen to form mercury oxide. This process is like sympathizing with spiritual objects, and mercury is like echoing with the clear air between heaven and earth, slowly transforming. The reaction formula is: 2Hg + O ³ $\ stackrel {\ triangle }{=\!=\!=}$ 2Hg O. The second is the displacement reaction. When mercury meets silver nitrate solution, mercury can replace silver from its salt solution, which is like a powerful treasure, showing the activity of mercury. The formula is: Hg + 2AgNO
Lead also has its own unique reaction. The oxidation reaction of lead is quite common. Lead oxidizes in the air for a long time, and lead oxide is formed on the surface, which seems to be covered with a layer of protective armor for lead. The reaction is as follows: 4Pb + 3O < 2 == 2Pb < 0 >. In addition, lead also reacts with acid. Take hydrochloric acid as an example, lead reacts with hydrochloric acid to produce hydrogen and lead chloride, just like lead releases internal energy under the stimulation of acid. The reaction formula is: Pb + 2HCl === PbCl ³ + H2O ↑.
Dansha is decomposed by heating. When Dansha is heated, it decomposes into mercury and sulfur, as if breaking the inherent form and releasing the spiritual things contained in it. The reaction formula is: HgS $\ stackrel {\ triangle }{=\!=\!=}$ H g + S.
Methoxylbenzene, as an organic substance, its substitution reaction is relatively typical. For example, under certain conditions, methoxylbenzene meets bromine elemental, and bromine atoms can replace hydrogen atoms on the benzene ring to generate bromomethoxylbenzene. This process, like a subtle change, interprets a unique chemical chapter at the molecular level.
These are all common reaction types of mercury, lead, dansha, and methoxybenzene. They are of great significance in ancient alchemy and today's chemistry, showing the wonders of material changes, such as the hidden order between heaven and earth.