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Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro-

Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro-

Hongda Chemical

    Specifications

    HS Code

    364874

    Chemical Formula C7H5BrClF
    Molar Mass 223.47 g/mol
    Solubility In Water Insoluble (organic compound, non - polar nature)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Vapor Pressure Low (due to relatively high molar mass and non - volatile nature)

    As an accredited Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 2-(chloromethyl)-4 - fluorobenzene in sealed chemical - grade container.
    Storage Store “Benzene, 1 - bromo - 2 - (chloromethyl)-4 - fluoro -” in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly closed container made of materials compatible with the chemical, such as glass or certain plastics. Segregate from oxidizing agents, bases, and reactive metals to prevent potential reactions.
    Shipping Shipment of "Benzene, 1 - bromo - 2 - (chloromethyl)-4 - fluoro -" must follow strict chemical transport regulations. Use appropriate, labeled containers. Ensure proper packaging to prevent leakage during transit.
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    Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro- Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro-
    General Information
    Historical Development
    In the past, there were chemists who studied a substance called "Benzene, 1 - Bromo - 2 - (Chloromethyl) -4 - Fluoro -". At first, people did not explore the field of chemistry deeply, and they knew very little about it.
    As the years passed, scholars devoted themselves to studying it, and gradually understood its nature through many experiments and analysis methods. In the past, the experimental methods were limited and the progress was slow, but everyone was determined.
    With the passage of time, technology has advanced, and the understanding of "Benzene, 1 - Bromo - 2 - (Chloromethyl) -4 - Fluoro-" has become more and more thorough, knowing that it has potential applications in many fields such as chemical industry and medicine. From the initial ignorance to the clarification of its characteristics and value today, the research process of this substance is really a witness to the development of chemistry, and it also paves the way for future generations to explore the unknown chemical world.
    Product Overview
    Product Overview
    There is currently a product named 1-Bromo-2- (chloromethyl) -4-fluorobenzene (Benzene, 1-Bromo-2- (Chloromethyl) -4-Fluoro-). It is an organic compound with one bromine atom, one chloromethyl atom and one fluorine atom on the benzene ring in the structure.
    This product is valuable in the field of organic synthesis. Bromine atoms are highly active and can participate in nucleophilic substitution reactions. They interact with many nucleophilic reagents, introduce different functional groups, and expand the diversity of compound structures. Chlorine atoms in methyl chloride are also active, and can initiate a series of reactions under specific conditions, providing the possibility for the construction of complex organic molecules. The existence of fluorine atoms significantly affects the physical and chemical properties of compounds due to the characteristics of fluorine elements, such as enhancing fat solubility and improving stability.
    In chemical research and production, 1-bromo-2- (chloromethyl) -4-fluorobenzene is often used as a key intermediate, laying the foundation for the preparation of a variety of biologically active drugs and functional materials, and promoting the development and progress of organic chemistry.
    Physical & Chemical Properties
    The physicochemical properties of 1-bromo-2- (chloromethyl) -4-fluorobenzene are particularly important. Looking at its morphology, it may be liquid at room temperature, colored or nearly colorless, and has a certain volatility. Physical constants such as boiling point and melting point are the keys to characterize its characteristics. The boiling point is related to the temperature of its gasification, and the melting point determines the transition node between its solid state and liquid state.
    In terms of autochemical properties, its structure contains halogen atoms, so it has certain reactivity. The existence of bromine, chlorine, and fluorine atoms makes the distribution of molecular electron clouds different, causing it to exhibit unique behaviors in reactions such as nucleophilic substitution. It can react with many nucleophilic reagents to generate new compounds. These physical and chemical properties have great application value in the fields of organic synthesis and other fields, and cannot be ignored in chemical research and actual production.
    Technical Specifications & Labeling
    Today there is a thing called 1-bromo-2- (chloromethyl) -4-fluorobenzene. To clarify its technical specifications and identification (commodity parameters), you should check it carefully.
    This compound has a benzene ring as the base, and bromine atoms, chloromethyl atoms, and fluorine atoms are in their respective positions. Its technical specifications are related to purity, and it needs to reach a very high level, and the impurity content must be minimal before it can be used. Its properties should have a specific color and state, and the smell must also conform to the established standards.
    In terms of identification, the commodity parameters should be clear, including molecular weight, molecular formula, and other data. On the packaging, the logo must be accurate, clearly indicating the name, specifications, warnings and other important items, so that the user can see at a glance, use it correctly and safely. In this way, the 1-bromo-2 - (chloromethyl) -4-fluorobenzene that meets the technical specifications and labels (commodity parameters) is also.
    Preparation Method
    This product of Benzene, 1 - Bromo - 2 - (Chloromethyl) -4 - Fluoro - is prepared as follows: Prepare raw materials first, and need suitable bromide, chloromethyl-containing raw materials and fluoride, etc. The first derivative of benzene is taken, and the bromine atom is attached to a specific position in the benzene ring by a specific process. This step requires temperature control and selection of suitable catalysts, such as iron filings, to promote the anterograde bromide reaction. Then chloromethyl is introduced. When using suitable reagents, operate in sequence, pay attention to the reaction conditions, and prevent side reactions from occurring. After introducing fluorine atoms, this process also requires precise temperature control and catalyst selection, so that the fluorine atoms reach the expected check point. After each step of the reaction, it needs to be separated and purified to remove impurities and obtain pure products. After these steps and rigorous operation, this Benzene, 1 - Bromo - 2 - (Chloromethyl) -4 - Fluoro - product can be prepared.
    Chemical Reactions & Modifications
    The wonders of chemical industry are related to reaction and change. Today there is a substance Benzene, 1 - Bromo - 2 - (Chloromethyl) - 4 - Fluoro -, which is quite important in the field of chemistry and the study of reaction and change.
    Looking at the reaction, it can be promoted by various methods. However, the rate of reaction and the amount of production depend on the right conditions. Temperature, pressure, and catalysis are all key. Either control the temperature to a moderate level, or add a catalytic agent to increase the speed of the reaction and increase the amount of production.
    As for the change property, this substance may produce new substances due to reaction, and its properties are also different. Or have stronger activity, or have different sexual characteristics. The study of this change is of great significance to the progress of chemical industry and the production of new materials. It is necessary to observe its changes carefully in order to grasp them accurately and contribute to the progress of chemistry.
    Synonyms & Product Names
    A chemical, named "Benzene, 1 - Bromo - 2 - (Chloromethyl) -4 - Fluoro -", has many aliases and trade names.
    The aliases of this substance are due to differences in chemical naming rules, or due to different research perspectives. Although its core structure and composition have not changed, the titles are different.
    As for the trade name, it is the merchant who started to promote this product. Different merchants give them unique trade names according to factors such as their market positioning, target customer groups, and product uses.
    When we study this object, we need to understand its various nicknames and trade names to avoid confusion due to different titles, to ensure the accuracy of the research, and to explore the chemical industry in order to move forward smoothly.
    Safety & Operational Standards
    1-Bromo-2- (chloromethyl) -4-fluorobenzene safety and operating specifications
    Fu 1-bromo-2- (chloromethyl) -4-fluorobenzene is also a chemical research material. Its properties need to be carefully observed, safety and operating standards are paramount, and should not be ignored.
    In the way of storage, it should be placed in a cool, dry and well-ventilated place. Avoid water and fire, and stay away from heat sources to prevent accidents. Because of its risk of explosion, fireworks are strictly prohibited in the place of storage. And it should be separated from oxidants, strong alkalis and other substances to avoid biochemical reactions and cause crises.
    When taking it, it is necessary to wear protective gear. Such as anti-corrosive gloves, which can avoid touching the skin and avoid damaging the body; anti-goggles, which can protect the eyes and prevent splashing in. It is better to operate in the ventilation cabinet, so that the exhaust gas can be discharged quickly, so as not to stay in the room and harm the person.
    If you accidentally touch the skin, rinse it with a lot of water, and then wash it with soap. If it enters the eye, immediately open the eyelids, buffer it with water, and seek medical attention as soon as possible. If you eat it by mistake, do not induce vomiting, seek medical attention quickly, and follow the doctor's advice.
    After the experiment, the residue should not be discarded at will. When in accordance with relevant regulations, properly dispose of it to prevent pollution of the environment and leave a disaster to future generations. The instrument also needs to be cleaned for reuse.
    In short, in the research of 1-bromo-2- (chloromethyl) -4-fluorobenzene, safety is the first priority, and the operation is in accordance with regulations, so as to avoid disasters, protect the body and promote the smooth progress of the research.
    Application Area
    In the field of pharmaceutical research and development, this substance can be used as a key intermediate. With its unique structure, it can synthesize many drugs with specific curative effects, or it can fight difficult diseases and relieve the suffering of patients. In the field of materials science, it also has extraordinary performance. Based on it, through special processing, it can produce new materials with excellent performance, which can be used in cutting-edge fields such as electronics and aerospace to improve the properties of materials and promote the progress of science and technology. Furthermore, in the fine chemical industry, it can be used as a raw material to participate in the preparation of a variety of fine chemicals, enhancing the function and value of products and promoting industrial upgrading.
    Research & Development
    There is a chemical substance today, named "Benzene, 1 - Bromo - 2 - (Chloromethyl) -4 - Fluoro -". As a chemical researcher, I am dedicated to the research and development of this substance.
    This substance has strange properties and is related to various fields of chemical industry and medicine. It has great potential. I started by using ancient books as the basis to study the theories of predecessors and understand its physical and chemical properties. Then, I entered the laboratory, used exquisite tools, and performed various experiments. Observe the changes in its reaction, and record the exact number.
    During the research and exploration, I encountered many difficulties. The reaction conditions are harsh, and it is difficult to purify the raw materials. However, I have not been discouraged, I have repeatedly adjusted the plan, and after repeated attempts, I have gradually obtained the best method. Today, its synthesis has been proven, and the yield has also been improved.
    Looking forward to the future, we hope to use this product as a basis and explore new fields of use. Hope that it will be created in medicine and become a good medicine for curing diseases; in chemical production, it will be an innovative raw material. Unremitting efforts will be made to promote the research and development of this chemical product, so as to benefit the world.
    Toxicity Research
    I have heard many wise men talk about the nature of poisons, and I have also mentioned one today. The name of this substance is 1-bromo-2- (chloromethyl) -4-fluorobenzene, which is an organic compound. Let's look at its structure. The atoms of bromine, chlorine and fluorine are connected to the benzene ring, which may have unique toxicity.
    Halogen atoms are active, and the coexistence of bromine, chlorine and fluorine in this molecule may make it easy to react with molecules in the body of organisms. Such as invading biological cells, or breaking the structure of their membranes, disturbing the metabolism of cells. Or combining with proteins and nucleic acids, disrupting their normal functions and causing cell lesions.
    However, the depth of toxicity still needs many experiments to prove. Only by observing its impact on diverse organisms at different concentrations and environments can we determine the degree of toxicity and make strategies for protection and treatment.
    Future Prospects
    Today there is a thing called "Benzene, 1 - Bromo - 2 - (Chloromethyl) -4 - Fluoro-", and its development in the future is quite impressive. As chemical researchers, we can see its clues and observe its characteristics, and we can explore it in the future.
    This object has a delicate structure, and bromine, chloromethyl and fluorine atoms interact according to their positions, or have wonderful properties. In the future, it is expected to emerge in the field of materials. With its unique structure, new materials with excellent performance may be prepared, which can be used in electronics, optics and many other fields.
    Furthermore, on the stage of chemical reactions, it may be a substrate for new reactions, open up a new reaction path, and enrich the treasure house of chemical synthesis. We should study diligently and explore unremittingly, hoping to stimulate its potential, contribute to future scientific and technological progress, and achieve a grand achievement, which will live up to our original intention of research and seek well-being for future generations.
    Where to Buy Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro- in China?
    As a trusted Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Benzene, 1-Bromo-2-(Chloromethyl)-4-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of this product 1-bromo-2- (chloromethyl) -4-fluorobenzene?
    This substance is an (alkyl) ether compound. Its hydrocarbon-containing structure can be inferred from " (alkyl) ", and it is connected to the oxygen atom to form an ether bond. And "ether" indicates that it has the typical structural characteristics of ether compounds.
    In terms of chemical properties, first of all, it has relative stability. Although the oxygen atom in the ether bond (C-O-C) has a lone pair of electrons, due to the electron-induced effect of alkyl groups on both sides, the ether bond is relatively stable, and reactions such as ring opening are not easy to occur under normal conditions. For example, at room temperature and without the action of special reagents, the substance can maintain its own structural stability and does not react significantly with common weak acids and bases.
    Secondly, some reactions can occur under specific conditions. When encountering strong protonic acids, such as hydroiodic acid (HI), ether bond breakage occurs. This is because the protons provided by HI can bind to the oxygen atoms in the ether bond, enhancing the polarity of the C-O bond, which in turn makes the C-O bond more susceptible to breakage, resulting in the formation of corresponding alcohols and iodoalkanes. The reaction mechanism is roughly as follows: the protons first bind to the oxygen atoms in the ether to form a salt, and then the iodine ions attack the carbon atoms connected to the oxygen, resulting in the break of the ether bond.
    Furthermore, if the substance contains α-hydrogen atoms (hydrogen atoms on carbon atoms connected to ether bonds), under the action of appropriate oxidizing agents, α-hydrogen can be oxidized to form compounds containing carbonyl groups such as aldodes or ketones. However, this reaction usually requires specific catalysts and suitable reaction conditions to proceed smoothly.
    In summary, the chemical properties of this (alkyl) ether-allyl not only reflect the relative stability of ether compounds, but also under specific conditions, characteristic reactions such as ether bond cracking and α-hydroxidation can occur.
    In what fields is 1-bromo-2- (chloromethyl) -4-fluorobenzene used?
    1 + -Benzyl-2- (methoxybenzyl) -4-chlorobenzene, this compound is used in the fields of medicine, pesticides and materials. The details are as follows:
    ** Pharmaceutical field **:
    The specific group combination in its structure imparts unique pharmacological activity. In the process of antimicrobial drug development, researchers found that the compound exhibited inhibitory effects on some Gram-positive and negative bacteria. Because its structure can bind to key metabolic enzymes or biosynthetic pathway-related proteins in bacteria, interfere with normal physiological activities of bacteria, and hinder bacterial growth and reproduction, it may be used as a lead compound to develop new antimicrobial drugs through structural modification and optimization to deal with drug-resistant bacterial infections. In the research of anti-tumor drugs, it has also made its mark. In vitro cell experiments have shown that it exhibits cytotoxicity to some tumor cell lines, which may inhibit the growth of tumor cells by affecting the proliferation and apoptosis signaling pathways of tumor cells, opening up a new direction for the development of anti-tumor drugs.
    ** Pesticide field **:
    With its unique mechanism of action against insects, plant pathogens, etc., it has great potential in the creation of pesticides. For pests, it can interfere with the nervous system or endocrine system of pests, causing their behavior disorders, growth and development to be blocked, and eventually death. Or it can be developed into new pesticides to prevent and control agricultural pests, reduce the amount of chemical pesticides, and reduce environmental pollution. Aimed at plant pathogens, it can inhibit the cell wall synthesis, respiration or energy metabolism process of pathogens, prevent pathogens from infecting plants or inhibit their spread in plants, and lay the foundation for the development of high-efficiency and low-toxicity fungicides, ensure the healthy growth of crops, and improve the yield and quality of agricultural products.
    ** Material field **:
    Because of its special chemical structure and properties, or can be used to synthesize polymer materials with special functions. When polymerized with other monomers, it gives polymer materials unique optical, electrical or thermal properties. For example, synthetic polymer materials may have good fluorescence properties and be used in the field of optoelectronic display materials to prepare high-brightness, high-resolution display devices; or they may be used as high-performance engineering plastics with special thermal stability and mechanical properties. They are used in aerospace, automotive manufacturing, and other fields that require strict material properties.
    What are the methods for preparing 1-bromo-2- (chloromethyl) -4-fluorobenzene?
    To prepare 1-bromo-2- (methoxy) -4-chlorobenzene, it can be obtained from the classical organic synthesis method.
    First, the halogenation reaction is used as the basis. First, take a suitable benzene derivative, which has a substituent such as methoxy group. Use halogenating reagents, such as brominating agents and chlorinating agents, to halogenate it at a specific position in the benzene ring under appropriate reaction conditions. For example, liquid bromine and a suitable catalyst, such as iron filings or iron tribromide, can be selected to control the reaction temperature and time, so that the bromine atom is precisely replaced at the target position; similarly, choose a suitable chlorinating reagent, such as chlorine gas or sulfoxide chloride, to introduce chlorine atoms under suitable conditions. However, this process requires fine regulation of the reaction conditions, because the localization effect of the existing substituents on the benzene ring will affect the selectivity of the halogenated position.
    Second, the nucleophilic substitution reaction strategy is adopted. If there is a suitable halogenated benzene-containing substrate, and the adjacent para-site of the halogen atom has a suitable leaving group, and the methoxy group can be introduced by the corresponding nucleophilic reagent. If halogenated benzene is used as the raw material, under basic conditions, it reacts with nucleophilic reagents such as sodium methoxide, and the methoxy negative ion attacks the adjacent para-site of the halogen atom on the benzene ring, and a nucleophilic substitution reaction occurs to construct the target molecular structure. In this regard, attention should be paid to the activity of the substrate and the nucle
    Third, multiple steps such as diazotization may be considered. The amino-containing benzene derivative is first prepared. After diazotization, different substitution reagents are used to introduce bromine atoms and chlorine atoms, and finally methoxy groups. The diazotization reaction requires specific conditions such as low temperature, and the selectivity and yield of subsequent substitution reactions need to be carefully controlled to achieve the purpose of synthesizing 1-bromo-2- (methoxy) -4-chlorobenzene. However, there are many steps in this path, and each step needs to be properly planned to improve the overall synthesis efficiency.
    What are the market prospects for 1-bromo-2- (chloromethyl) -4-fluorobenzene?
    At present, the market prospect of 1 + -alcohol-2- (hydroxymethyl) -4-cresol is quite promising.
    Alcohol compounds are crucial in many fields. 1 + -alcohol-2- (hydroxymethyl) -4-cresol has both the characteristics of alcohol and the advantages of specific substituents. In the pharmaceutical industry, it may be used as a key intermediate for the synthesis of many drugs. Due to its chemical structure, it can endow drug molecules with specific activities and functions, and help to develop new drugs to treat various diseases, so the demand for it in the pharmaceutical market may be increasing.
    In the chemical industry, it can be used as a synthetic raw material for high-performance materials. With its unique chemical activity and ingenious chemical reaction, polymers, resins and other materials with excellent performance can be prepared, which are widely used in coatings, adhesives and other fields to meet the diverse needs of industrial production and daily life for material properties. This will also expand its market space.
    Furthermore, with the rapid development of science and technology, emerging fields also bring opportunities. For example, in the field of electronic materials, the demand for special chemicals is increasing day by day. 1 + -alcohol-2- (hydroxymethyl) -4-cresol may find a place in the research and development and production of electronic chemicals due to its unique physical and chemical properties, further expanding the market scope.
    However, it should also be noted that although the market prospect is good, the competition may become fierce. With its potential value highlighted, many manufacturers must be attracted to production. To gain a firm foothold in the market, it is necessary to focus on R & D innovation, improve product quality, optimize production processes, reduce costs and increase efficiency, in order to win the lead in the unpredictable market and enjoy the benefits brought by this broad market prospect.
    What are the precautions for the use of 1-bromo-2- (chloromethyl) -4-fluorobenzene?

    First of all, this substance is toxic and dangerous. Mercury, known to be highly toxic, can harm various organs of the human body, especially the nerves and kidneys. Cyanomethyl compounds involved, many of which are highly toxic, can cause serious danger and endanger life. Chlorobenzene is also toxic. Long-term exposure to it can damage the hematopoietic, nervous and other systems.
    Second rule, use it in strict accordance with the procedures. All operations involving these poisons should be carried out in a place that meets safety standards. It is necessary to use protective gear, such as gas masks, gloves, protective clothing, etc., to prevent poisons from entering the body. And the operator must be familiar with the operation method and emergency measures. If there is accidental touch, accidental sniffing, etc., they can quickly take appropriate measures to save themselves.
    Furthermore, storage should also be careful. It should be placed in a cool, dry, well-ventilated place, protected from light and heat, and kept separate to prevent more dangerous things from interacting with each other. The stock and use of it should be recorded in detail for inspection and management.
    Repeat, the waste is also heavy. The used items should not be discarded at will. They must be handled in accordance with environmental regulations and special laws to prevent pollution of the environment and harm all living beings.
    In short, in the use of (1 + -mercury-2- (cyanomethyl) -4-chlorobenzene), it is necessary to respect them, strictly abide by regulations, and handle them carefully to ensure people's safety and peace.