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What are the chemical properties of Benzene, 1- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -4- (Trifluoromethoxy) -
This is an organic compound called 1- (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) -4- (trifluoromethoxy) benzene. Its chemical properties are rich and unique.
From the structural point of view, the benzene ring is a stable six-membered ring structure, which endows the compound with certain aromaticity. The 1 - (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) connected to the benzene ring, due to the existence of the dicyclohexyl structure, adds the three-dimensional complexity and steric hindrance of the molecule. The ethyl side chain can enhance the lipid solubility of the molecule and promote its solubility in organic solvents.
The fluorine atom in the 4- (trifluoromethoxy) part of the trifluoromethoxy group has strong electronegativity, which makes the group strong electron-absorbing. This property significantly affects the electron cloud distribution of the molecule, which in turn changes the electron density of the benzene ring. Causes the change of the electrophilic substitution activity of the benzene ring, which is more prone to nucleophilic substitution than benzene.
In terms of physical properties, due to the existence of large hydrocarbon groups and fluorine-containing groups in the molecule, it is speculated that its melting point, boiling point or intermolecular force. The Van der Waals force between hydrocarbons and the weak interaction involving the fluorine atom may work together to make the melting point and boiling point of the compound within a certain range. And due to the hydrophobicity of fluorine-containing groups, its solubility in water or low, easily soluble in organic solvents.
Chemical stability, the conjugated system of benzene ring imparts certain stability, but the electron-absorbing effect of trifluoromethoxy may reduce the electron cloud density of the ortho and para-position of the benzene ring, and under certain conditions, it is vulnerable to attack by nucleophiles. At the same time, the side chain part may undergo oxidation, substitution and other reactions under appropriate conditions. In short, the chemical properties of this compound are determined by its unique structure, and it may have potential application value in the fields of organic synthesis and materials science.
What are the uses of Benzene, 1- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -4- (Trifluoromethoxy) -
Eh! Benzene, 1- (4 '-ethyl [1,1' -dicyclohexyl] -4-yl) -4- (trifluoromethoxy), has a wide range of uses.
In the field of medicine, this compound may have unique activities. It has a delicate structure, specific intermolecular interactions, or can fit with specific biological targets. If it can precisely connect the activity of protein receptors or enzymes, it can regulate the physiological and biochemical processes in organisms, and is expected to lay the foundation for the creation of new drugs, such as anti-inflammatory and anti-tumor medicines, which may be bred from it.
In the field of materials science, it also has potential. Because it contains special functional groups, such as trifluoromethoxy, it gives the material special properties. Or it can enhance the stability of the material, making it not easy to deteriorate and decompose in extreme environments; or it can improve the surface properties of the material, such as hydrophobicity and fouling resistance, making it stand out in coatings, membrane materials, etc., and can be used to make high-end waterproof and anti-fouling materials.
Furthermore, in the field of organic synthetic chemistry, this compound is an important intermediate. Using it as a starting material, through various chemical reactions, such as substitution, addition, oxidation, etc., many compounds with novel structures can be derived. Chemists use this to expand the compound library, explore new reaction paths and mechanisms, promote the vigorous development of organic synthesis chemistry, and open up avenues for the creation of more practical organic compounds.
In short, benzene, 1- (4 '-ethyl [1,1' -dicyclohexyl] -4-yl) -4- (trifluoromethoxy) has unlimited potential in many fields such as medicine, materials, and organic synthesis, and is an important compound worthy of further investigation.
What is the synthesis method of Benzene, 1- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -4- (Trifluoromethoxy) -
The synthesis of 1- (4 '-ethyl [1,1' -dicyclohexyl] -4-yl) -4- (trifluoromethoxy) benzene is a key issue in organic synthetic chemistry. The synthesis path requires delicate strategies and superb skills.
First, the appropriate starting material should be found. Benzene derivatives with specific substituents and dicyclohexyl derivatives can be selected as groups. The structure of the capped benzene ring and dicyclohexyl is the core structure of the target molecule. Here, the purity and activity of the starting material are crucial, and its quality can determine the success or failure of the synthesis.
Second, the reaction steps must be carefully designed. Or it can be halogenated first to introduce halogen atoms at specific positions in the benzene ring to facilitate subsequent nucleophilic substitution reactions. In the nucleophilic substitution reaction, trifluoromethoxy negative ions can be substituted with halogenated benzene, thereby introducing trifluoromethoxy groups. This step requires strict control of reaction conditions, such as temperature, solvent, type and dosage of base, etc. If the temperature is too high or too low, side reactions can occur, affecting the yield and purity of the product.
Furthermore, the construction and connection of the dicyclohexyl part is also critical. Or a coupling reaction can be used to connect the ethyl-containing dicyclohexyl fragment to the benzene ring that has been introduced into the trifluoromethoxy group. In this process, the choice of catalyst is very important. High-efficiency catalysts can accelerate the reaction process and improve the selectivity of the reaction.
And in the synthesis process, the separation and purification of the reaction products at each step is also indispensable. Column chromatography, recrystallization and other means can be used to remove impurities and obtain a pure product. This is not only related to the quality of the final product, but also of great significance for subsequent research and application.
Synthesis of 1- (4 '-ethyl [1,1' -dicyclohexyl] -4-yl) -4- (trifluoromethoxy) benzene requires comprehensive consideration of all reaction links and careful operation to achieve high-efficiency and high-quality synthesis goals.
What are the physical properties of Benzene, 1- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -4- (Trifluoromethoxy) -
1 - (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) - 4 - (trifluoromethoxy) benzene has unique physical properties. In its color state, it is mostly a colorless and transparent liquid at room temperature, and it looks like a clear spring, clear and free of impurities. Due to the regular molecular structure and appropriate intermolecular forces, the molecules can move more freely, thus presenting a liquid state.
Its smell is slightly aromatic, but it is different from the common benzene aromatic. Due to the introduction of trifluoromethoxy, the smell is mixed with a different smell, which seems to be fresh and rich. This unique smell comes from the interaction of the benzene ring structure and fluorine-containing groups in the molecule.
Talking about the boiling point, at a specific temperature range, there is a van der Waals force and a dipole-dipole force between molecules. Alkyl and fluorinated groups increase the attraction between molecules, resulting in higher energy to overcome the attractive force, so that the molecule leaves the liquid phase and changes to the gas phase, so the boiling point is in a certain range.
In terms of solubility, it has good solubility in organic solvents such as toluene and dichloromethane. This is because of the principle of similar miscibility. The molecules of this substance have certain hydrophobicity and can form similar forces with organic solvent molecules, which can be well mixed with each other. However, the solubility in water is very small, because its molecular structure is hydrophobic as a whole, it is difficult to form effective interactions with water molecules.
The density is slightly lighter than that of water. When placed in water, it can be seen that it floats on the water surface, just like oil floats on the water. This is determined by the molecular composition and structure, and the type and arrangement of its atoms make the mass per unit volume smaller than that of water.
The physical properties of this substance are closely related to its unique molecular structure, and the groups interact with each other to create such physical properties.
Benzene, 1- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -4- (Trifluoromethoxy) - What is the impact on the environment
1 - (4 '-ethyl [1,1' -bicyclohexyl] -4-yl) -4 - (trifluoromethoxy) benzene is involved in the environment and is related to both ecology and health.
At the ecological level, first, it may be significantly toxic to aquatic organisms. The part of the trifluoromethoxy group in its chemical structure has unique properties or is difficult to degrade. Once it enters the water body, it can exist in it for a long time, interfering with the normal metabolism, growth and reproduction of aquatic organisms. For example, it can hinder the function of fish respiratory organs, causing their respiration to be blocked, and even endangering life. Second, it also has an impact on soil ecology. If it accumulates in the soil, or changes the structure and function of soil microbial community. Soil microorganisms are essential for soil nutrient cycling and decomposition of organic matter, and their disturbance will affect soil fertility and plant growth.
It is related to health risks. If its vapor or aerosol is inhaled, it can irritate the respiratory tract and cause symptoms such as cough and asthma. Long-term exposure may have adverse effects on the human nervous system and endocrine system. Due to its complex structure, it is difficult for the human body to metabolize this substance, or it can accumulate in the body, interfering with neurotransmitter transmission and affecting hormone balance.
Therefore, such compounds need to be used and disposed of with caution. In the production process, the process should be optimized to reduce emissions; after use, the waste containing this material should be properly disposed of to prevent it from entering the environment indiscriminately, causing ecological damage and health threats.