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Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone]

Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone]

Hongda Chemical

    Specifications

    HS Code

    382981

    Chemical Formula C21H14F2O2
    Molecular Weight 334.336 g/mol
    Appearance Solid (usually white to off - white powder)
    Melting Point Typically in a certain range (experimental determination required)
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Solubility In Water Insoluble in water
    Density Needs experimental measurement
    Flash Point Requires experimental determination
    Purity Can vary depending on production method, usually expressed as a percentage

    As an accredited Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone] factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of Benzene - 1,3 - diylbis[(4 - fluorophenyl)methanone] packaged in a sealed container.
    Storage **Storage of Benzene - 1,3 - diylbis[(4 - fluorophenyl)methanone]**: Store this chemical in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent exposure to moisture and air, which could potentially lead to degradation. Avoid storing near oxidizing agents or reactive substances to prevent chemical reactions.
    Shipping Benzene - 1,3 - diylbis[(4 - fluorophenyl)methanone] should be shipped in well - sealed, corrosion - resistant containers. Ensure compliance with hazardous chemical shipping regulations, with proper labeling indicating its nature for safe transportation.
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    Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone] Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone]
    General Information
    Historical Development
    I have dedicated myself to the research of chemical substances, and today I am talking about the substance Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]. Its beginning was the hard work of the chemists of the ancestors in the garden of chemistry with perseverance and wisdom. At the beginning, the cognition was still shallow, and only a few or two of its characteristics were known. However, as the years passed, the sages worked tirelessly, and with advanced instruments and exquisite methods, they gradually understood the mystery of its structure and the subtlety of its properties. From ignorance to clarity, from one-sided to comprehensive, the research process of this substance is like a long river gushing, magnificent. Many scholars have worked hard, either in the laboratory day and night, or repeatedly in the classics, eventually making the development of this substance gradually clear, laying the foundation for future use, and making great contributions to the advancement of chemistry.
    Product Overview
    There is a substance called Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]. The structure of this substance is based on the benzene ring, and there are two groups connected to its 1,3 positions. Each group has a (4-fluorophenyl) methanone structure. Its appearance or a specific form, and its texture is also unique.
    This substance has its uses in the field of chemistry, or in organic synthesis. Because of its specific molecular structure, it may participate in various reactions to generate other types of compounds, contributing to the research and development of organic chemistry. We chemical researchers should study its properties and reaction mechanisms in detail, in order to expand the boundaries of chemical cognition and make this substance available to humans for the benefit of the world.
    Physical & Chemical Properties
    Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone] is also an organic compound. Its physical and chemical properties are related to the importance of chemical research. Looking at its physical properties, under room temperature, or in a solid state, it has a specific color and shape. Its melting boiling point has a certain number due to intermolecular forces.
    On its chemical properties, the structure of the benzene ring gives it unique reactivity. Substituents on the benzene ring, such as fluorophenyl and methanone, affect its electrophilic substitution and other reactions. The carbonyl group of the methyl ketone group can react with nucleophiles, and the electronegativity of the fluorine atom also affects the distribution of the molecular electron cloud, which in turn affects the difficulty and direction of the reaction. This compound may have potential applications in fields such as organic synthesis, and chemists need to explore it in depth to clarify its more physical and chemical properties and contribute to the development of chemistry.
    Technical Specifications & Labeling
    Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone] This product is very important in terms of process specifications and identification (product parameters). Its process specifications, from the selection of raw materials, must be pure and fine, and the impurities must be fine. The preparation method should be carefully controlled according to precise procedures, the temperature of the reaction, the time, and the proportion of the agent. As for the identification (product parameters), its physical and chemical properties, such as the point of melting and boiling, solubility, etc., must be detailed in the book. And its structure formula should also be clearly presented, so that viewers can understand the structure of its molecules. In this way, the alignment of process specifications and identification (product parameters) is beneficial to the quality and use of products.
    Preparation Method
    To prepare Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone], prepare various raw materials. Take an appropriate amount of 1,3-dibromobenzene and 4-fluorophenylboronic acid as the base material. With a palladium catalyst, such as tetra (triphenylphosphine) palladium, in a alkaline environment, often potassium carbonate aqueous solution, Suzuki coupling reaction is carried out. The temperature is about 80 to 100 degrees Celsius, and the two are coupled when stirred for a number of times. After the reaction is completed, it is purified by extraction, column chromatography, etc. The extraction is carried out with an organic solvent such as dichloromethane, and the silica gel column is selected by chromatography, and the suitable eluent is separated. In this way, the product of Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone] can be obtained through the steps of raw material compatibility, reaction control, purification and refining.
    Chemical Reactions & Modifications
    A certain chemist, studying the change of substances, found Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]. The chemical response, related to the change of its properties, is the key to research.
    During this reaction, the molecule clutches, the bond is easier, and the new substance is formed. Its response is also, or speed or slow, subject to the properties of temperature, pressure, and catalysis. To improve its properties, it is necessary to carefully observe the joints of the reaction and control all elements.
    If the temperature is adjusted properly, it can promote the movement of molecules, increase the chance of collision, and make the response fast and complete. And choose a good reminder, which can reduce the energy barrier of the response, so that it can be easily achieved. Modify its structure, or add groups, it can also change its properties to suit different needs.
    Detailed study of chemistry and good improvement of physical properties, in order to make progress in the research of substances and create things.
    Synonyms & Product Names
    In the course of my generation's chemical research, the name of the substance is often involved. Today, there is a thing whose scientific name is called "Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]". This chemical term is precise and detailed, and it is used in the market, often replaced by aliases or trade names.
    Finding its synonymous name is something that cannot be ignored in scientific research. Knowing synonymous names is like holding the key to cognition in different fields, which can enable my generation to travel freely between academic exchanges and industrial applications. And the trade name is closely related to the actual production and sales.
    Or due to different regions and industry habits, the name of the same substance varies. Our generation should explore in detail and clarify its synonymous names and trade names, so that we can advance steadily in the way of chemical research and application, without being trapped by the confusion of names and names, in order to achieve a deep state.
    Safety & Operational Standards
    About Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone] Product Safety and Operation Code
    Fu Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone] is an important substance in chemical research. Safety and standardized operation are of paramount importance during its research and use.
    First word safety. This substance has specific chemical properties, or may pose latent risks to the human body and the environment. Proper protective measures are necessary in the experimental site. Researchers need to wear professional protective clothing, protective gloves and goggles to prevent skin-eye contact. Because it may be irritating, if you accidentally touch it, rinse it with plenty of water as soon as possible and seek medical attention as appropriate. And the volatile gas of the substance may be harmful to health. The experimental area must be well ventilated, and a fume hood should be set up to disperse harmful gases, keep the air fresh, and protect the health of the researcher.
    Times and operating specifications. When taking this product, use a precise measuring tool and measure it accurately according to the experimental requirements. Do not waste it, and avoid excessive reaction deviation. During operation, strictly observe the experimental steps and do not change it without authorization. When mixing other substances, add it slowly and stir it while adding to make the reaction smooth. Be especially careful when heating the reaction, control the temperature and time, and prevent danger caused by overheating. After the reaction, properly dispose of the remaining substances and waste, collect them in accordance with the chemical waste treatment rules, and hand them over to professional institutions for disposal. Do not discard them at will to avoid polluting the environment.
    In short, when researching Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone], safety is always the priority, and operating standards are followed to ensure the smooth operation of the experiment and protect yourself and the environment.
    Application Area
    Today there is a product called "Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone]". This product is quite capable in various application fields.
    The field of Guanfu medicine, which can assist in the research of new drugs to treat diseases. Because of its unique structure, it can cooperate with the biochemical mechanism in the body, or regulate the metabolism of cells, or prevent the reproduction of pathogens, which is a good aid for treating diseases and health.
    In the world of materials, it can also be used. With its characteristics, it can be added to various materials, which can change the properties of the material, increase its toughness and heat resistance, and make the material suitable for a wider range of situations, such as aerospace equipment and precision instruments.
    And in chemical synthesis, it can be a key agent. Leading it to participate in the reaction can lead the direction of the reaction, obtain specific products, expand the chemical category, and promote the progress of the chemical industry. All of this shows that "Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone]" has an extraordinary effect in the application field and has broad prospects.
    Research & Development
    To taste the way of scientific research, the most important thing is to study and explore new ones. Today there is a compound Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone], and its research and development are related to the advancement of the field of chemistry.
    Our generation has devoted themselves to studying this compound to explore its structure, properties and reaction mechanism. After repeated experiments, its physical properties have been observed and its chemical activity has been analyzed. In terms of reaction conditions, the influence of temperature, catalyst and other variables has been studied in detail, and the best synthesis path has been sought to improve the yield and purity.
    The development path also focuses on expanding its application field. Or used in material science to improve material properties; or involved in drug research and development to explore potential medicinal value. Although the road ahead is long, adhering to the spirit of research, we will be able to achieve remarkable results in the research and development of this compound, contributing to the progress of chemistry.
    Toxicity Research
    The toxicity of Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone] is studied. This substance is also worth testing in experimental studies. Take all things and place them together to observe their changes. See the encounter with active substances, often abnormal.
    Or some organisms are stained by it, and their vitality gradually decreases. Observe its cells, the structure and morphology are changed, and the metabolic path is also chaotic. Although the dosage is different, the existing signs are different, but the toxicity cannot be ignored. From this point of view, this chemical has hidden dangers in the environment and personal safety. Deep research can prevent its harm, maintain the tranquility of the habitat, and protect everyone's health.
    Future Prospects
    The future prospect of this chemical product is of paramount importance to our generation of chemical researchers. Today, when we discuss "Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]", its prospects are broad and fascinating.
    This chemical has a unique molecular structure and its performance is also extraordinary. Looking to the future, first, in the field of materials science, we may be able to use its characteristics to develop new high-performance materials, such as for electronic components, which can improve its stability and conductivity, and help the rapid progress of electronic technology. Second, in the field of medicinal chemistry, after in-depth exploration of its activity, it may become a key ingredient in innovative drugs, providing new opportunities for tackling difficult diseases.
    Although there may be difficulties and obstacles ahead, our generation upholds the spirit of research and exploration, and firmly believes that in the near future, we will be able to fully explore the potential of "Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone]", so that it can make outstanding contributions to human well-being and realize our beautiful vision for the future.
    Where to Buy Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone] in China?
    As a trusted Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone] manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Benzene-1,3-Diylbis[(4-Fluorophenyl)Methanone] supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]?
    Benzene-1,3-diyl bis [ (4-fluorophenyl) methanone] is one of the organic compounds. Its chemical properties are unique and worthy of detailed investigation.
    In this compound, the benzene ring is its core structure, and the 1 and 3 positions above it are respectively connected with the structure of bis [ (4-fluorophenyl) methanone]. The benzene ring has aromatic properties and is relatively stable, which can endow the compound with certain conjugate stability.
    In terms of its physical properties, the substance is in a solid state under normal conditions, and the melting boiling point varies depending on the intermolecular forces. The intermolecular force includes van der Waals force, and the introduction of fluorine atoms may enhance the intermolecular force, which in turn affects its melting boiling point.
    Chemically, the carbonyl group (the structural part of the ketone) is the active check point. The carbonyl group is polar, and in the carbon-oxygen double bond, the oxygen atom is highly electronegative, resulting in the carbon atom being partially positively charged and vulnerable to attack by nucleophilic reagents. For example, in the case of nucleophilic reagents, such as alcohols, amines, etc., the carbonyl carbon atom may undergo nucleophilic addition reaction.
    Furthermore, although the benzene ring is stable, substitution reactions can also occur under specific conditions. Because the fluorine atom is an electron-withdrawing group, the electron cloud density of the benzene ring will decrease, and the electrophilic substitution reaction activity will decrease slightly, and the substitution position may be affected by the joint localization effect of the fluorine atom and the carbonyl group.
    And because of its fluorine atom, the special properties of the fluorine atom make the compound have unique biological activities and optical properties. In terms of biological activity, or in the field of medicine, it shows potential value; in terms of optical properties, or due to the existence of the conjugate system of molecular structure, it presents specific fluorescence properties.
    What are the main uses of Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]?
    Benzene-1,3-diyl bis [ (4-fluorophenyl) methyl ketone], this substance has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to its structure containing specific functional groups and aromatic rings, it can precisely interact with targets in organisms, or has the potential to regulate biological activities. It can be used as a starting material for the development of anti-cancer, anti-inflammatory and other drugs. Other groups can be added by organic synthesis to create ideal pharmacological properties.
    In the context of materials science, it also has unique functions. Due to its stable molecular structure and fluorine atoms, it can be used to prepare high-performance polymer materials. Introducing it into the main chain or side chain of the polymer can improve the thermal stability, chemical stability and mechanical properties of the material. The prepared materials may be used in high-end fields such as aerospace, electronics and electrical appliances, such as aerospace components, electronic packaging materials, etc., and meet strict requirements with excellent properties.
    Furthermore, in the field of organic synthetic chemistry, it is an important building block for building complex organic molecules. Using various organic reactions, such as nucleophilic substitution, addition reactions, etc., to build multivariate structural compounds on it, providing a cornerstone for organic synthetic chemists to explore new reaction paths and create novel compounds, and helping to expand and innovate frontier research in organic chemistry.
    What is the synthesis method of Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]
    To prepare Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone], the following ancient method can be used.
    First take an appropriate amount of benzene-1,3-diborate pinacol ester and 4-fluorobenzoyl chloride as starting materials. In a clean reactor, first add an appropriate amount of organic solvent, such as anhydrous dichloromethane, to create a suitable reaction environment. Place the reactor in a low-temperature cooling device and let the temperature drop slowly to about 0 ° C. Slowly pour in 4-fluorobenzoyl chloride and stir well. This is to make the materials initially mixed and make the reaction easy to start.
    Next, dissolve benzene-1,3-diborate pinacol ester in an appropriate amount of organic solvent in another container, and then add it dropwise to the reactor. At the same time, add an appropriate amount of palladium catalyst, such as tetra (triphenylphosphine) palladium (0), and an appropriate amount of base, such as potassium carbonate aqueous solution. In this case, the palladium catalyst can promote the reaction, and the base can adjust the pH of the reaction system and assist the reaction to advance smoothly.
    Add it up, slowly raise it to room temperature, and continue to stir the reaction. During this period, the reaction process must be closely monitored, which can be monitored by means of thin layer chromatography (TLC). After the reaction is completed, pour the reaction mixture into an appropriate amount of water and extract it with dichloromethane several times. The organic phases are combined, washed with saturated saline water, and dried with anhydrous sodium sulfate.
    Finally, the dried organic phase is distilled in a vacuum distillation unit to remove the solvent, followed by column chromatography to purify the obtained crude product. Appropriate eluents are selected, such as the mixture of petroleum ether and ethyl acetate. After this step, pure Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone] can be obtained. During the whole process, attention should be paid to the precise dosage of materials and strict control of reaction conditions, so that the ideal product can be obtained.
    What is the price range of Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone] in the market?
    I don't know if "Benzene - 1,3 - Diylbis [ (4 - Fluorophenyl) Methanone]" is in the market price range. This is a more professional chemical substance, and its price is determined by many factors.
    First, purity is the key factor. If the purity is extremely high, it is close to scientific research grade, and can be used in high-end experiments or special industrial processes, the price must be high; if the purity is slightly lower, it is suitable for general industrial use, and the price may be slightly lower.
    Second, market supply and demand also have an impact. If there are many people who want it, but there are few products, the price will rise; if the supply exceeds the demand, the price may fall.
    Third, manufacturers and brands are different, and prices are also different. Well-known large factories, due to their sophisticated production processes and strict quality control, their product prices may be higher; while some small factory products may be relatively close to the people.
    Fourth, the amount of purchase is also related to the price. If you buy in bulk, you may get a discount, and the unit price will be reduced; if you only buy in small quantities, the price may be higher.
    To know the exact price range, you need to consult chemical product suppliers, distributors, or professional chemical product trading platforms in detail to get accurate prices.
    What are the safety and precautions of Benzene-1,3-Diylbis [ (4-Fluorophenyl) Methanone]
    The safety and precautions of benzene-1,3-diyl bis [ (4-fluorophenyl) methyl ketone] are related to the safety and operation of the user. This substance needs to be treated with caution in terms of safety. In terms of its chemical properties, the chemically active part of its structure may react with other substances, so when stored, it should be avoided in the same place as easily reactive substances. And its stability varies under different environmental conditions. High temperature, high humidity or strong light may cause its properties to change, so it should be stored in a cool, dry and dark place.
    In terms of precautions, the first protection. Those who handle this object should wear suitable protective equipment, such as gloves and goggles, to avoid contact with the skin and eyes. If you accidentally touch it, rinse it with plenty of water as soon as possible and seek medical attention according to the situation. Furthermore, the operation place must be well ventilated to prevent its volatile gas from accumulating in the air and causing potential harm.
    In addition, during the experiment or use process, when strictly following the operating procedures, accurately weigh and mix carefully, do not change the established process at will. The disposal of waste should not be ignored, and it must be properly disposed of in accordance with relevant laws and regulations to avoid polluting the environment and endangering all living beings. In this way, the safety of this object must be guaranteed to avoid disasters.