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Benzene, 1,2,4-Trifluoro-5-Iodo-

Benzene, 1,2,4-Trifluoro-5-Iodo-

Hongda Chemical

Specifications

HS Code

245904

Chemical Formula C6H2F3I
Molar Mass 272.0
Appearance Solid (predicted)
Boiling Point Estimated around 170 - 190 °C
Density Estimated around 2.1 - 2.3 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Low

As an accredited Benzene, 1,2,4-Trifluoro-5-Iodo- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2,4 - trifluoro - 5 - iodobenzene in a sealed, chemical - resistant bottle.
Storage Store “Benzene, 1,2,4 - trifluoro - 5 - iodo -” in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of a material resistant to chemical corrosion, such as glass or certain plastics. Isolate it from incompatible substances like oxidizing agents to prevent potential reactions.
Shipping "1,2,4 - Trifluoro - 5 - iodobenzene" is shipped in specialized containers compliant with chemical transport regulations. Packaged securely to prevent leakage, it's transported under conditions ensuring stability during transit to its destination.
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Benzene, 1,2,4-Trifluoro-5-Iodo- Benzene, 1,2,4-Trifluoro-5-Iodo-
General Information
Historical Development
About the development process of 1,2,4-trifluoro-5-iodobenzene
Ancient chemical research, the beginning of the micro-end, the exploration of the nature of the substance, a lot of trouble. 1,2,4-trifluoro-5-iodobenzene this compound, little known in the early days.
In the past, the chemical technology was not refined, and it was difficult to make this thing. However, the heart of a scholar, perseverance, in the long years, unremitting research.
At first, it was only possible to speculate on its possible structure and characteristics, and there was no effective preparation method. Later, as the chemical theory gradually enriched and the experimental methods became new, there was a way to explore its synthesis.
After countless attempts, the appropriate reaction conditions and raw material ratio were found. From the rough initial synthesis to the continuous optimization of the process to improve the purity and yield. This compound has gradually become a real product that can be produced from the theoretical idea. Its development has witnessed the progress of the chemical field, and it has also condensed the blood of scholars of all ages, paving the way for more related research in the future.
Product Overview
There is a substance today called "Benzene, 1,2,4-Trifluoro-5-Iodo-". This substance has a unique structure. On the benzene ring, fluorine atoms and iodine atoms are located in their respective positions. The positions 1, 2, and 4 are occupied by fluorine, and the positions 5 are occupied by iodine.
Looking at its physical properties, it is either liquid or solid at room temperature. Its color is transparent and colorless, or has a slight light color. This varies depending on the preparation method and purity. Its odor, whether it has a specific fragrance or an irritating taste, depends on the specific situation.
When it comes to chemical properties, due to the difference in electronegativity between fluorine and iodine, this substance has a unique reactivity. It can interact with many reagents, or undergo substitution reactions, or additive changes, and has great potential in the field of organic synthesis. It can be used as an intermediate to prepare other compounds, and it is expected to be used in many aspects such as medicine and materials. It is an existence that cannot be ignored in chemical research.
Physical & Chemical Properties
"On the physical properties and chemical properties of 1,2,4-trifluoro-5-iodobenzene"
1,2,4-trifluoro-5-iodobenzene is an organic compound. Its physical properties are mostly liquid at room temperature, with certain volatility, and have different solubility in specific solvents. Looking at its appearance, it is colorless and transparent, or microstrip color, which is related to purity.
When it comes to chemical properties, the stability of benzene rings makes them have the commonality of aromatic hydrocarbons. However, the substitution of fluorine and iodine adds unique activities. Fluorine atoms have strong electronegativity, which changes the electron cloud density distribution of benzene rings, which affects the electrophilic substitution reaction activity. Although the iodine atom is relatively large, it makes the molecular space structure more complex, and can be used as a leaving group in some reactions to participate in nucleophilic substitution and other reactions. This compound is often a key intermediate in the field of organic synthesis due to its unique physicochemical properties, assisting in the preparation of many fine chemicals.
Technical Specifications & Labeling
"On the Technical Specifications and Labeling (Product Parameters) of 1,2,4-Trifluoro-5-Iodobenzene"
There are 1,2,4-trifluoro-5-iodobenzene now. The technical specifications are related to the preparation method and need to follow a rigorous process. From the selection of raw materials, it is necessary to be pure and free of impurities, to the reaction conditions, the temperature and pressure are fixed, and there is no difference at all. The reaction vessel also needs to be adapted, and the material and volume are considered.
In terms of labeling, the product parameters should be clear. The proportion of ingredients contained and the geometry of purity should be clearly marked. Appearance, color and odor also need to be detailed. In this way, it is necessary for everyone to understand its characteristics and use it correctly, so as to achieve a state of fine craftsmanship and accurate identification, so that the industry can progress in an orderly manner.
Preparation Method
To prepare 1,2,4-trifluoro-5-iodobenzene, prepare all kinds of raw materials. Based on fluoride, iodide and benzene derivatives. The preparation method is to take an appropriate amount of benzene derivatives and place them in a clean reactor. Add a specific proportion of fluoride, and control the temperature to a moderate extent according to the ingenious process to make it slow down. This process requires fine control of the heat and observation of its reaction state.
After the fluoride and benzene derivatives are initially combined, add iodide. Adjust the reaction environment, or adjust the pressure, or control the flow rate, so that the iodide is also integrated into the reaction. During the reaction, a delicate catalytic mechanism is used to promote its efficient conversion. After the reaction is complete, the impurities are removed by the purification process to obtain pure 1,2,4-trifluoro-5-iodobenzene. The method of this preparation, the selection of raw materials and the reaction process all need to be precise in order to obtain high-quality products.
Chemical Reactions & Modifications
In Benzene, 1,2,4-Trifluoro-5-Iodo, it is especially important to taste the wonders of chemical industry. Its chemical reactions, or the genera involving substitution and addition, need to be carefully observed at every step. For example, the position of halogen, the properties of fluorine and iodine, all affect the direction of the reaction.
Those who change their properties are also the key. Or adjust their temperature, or change their agents, can make them different. The reaction of this substance should be studied in detail and the interaction of each substance can be understood. If you want to get the best effect, you must pay attention to the details, from the proportion of the reactants to the reaction environment, all of which cannot be ignored.
And the wisdom of ancient times, in the study of chemistry, also emphasizes empirical evidence and thinking. Our generation should follow its ambition and use scientific methods to study the secrets of Benzene, 1,2,4 - Trifluoro - 5 - Iodo - reaction and change, seek chemical progress, and benefit the world.
Synonyms & Product Names
Today there is a thing called "1,2,4-trifluoro-5-iodobenzene". In the field of chemical industry, it has many nicknames, similar to ancient names, and it is also called by others. This substance is in the industry, and the nickname echoes the trade name.
Watching this thing, "1,2,4-trifluoro-5-iodobenzene" is its scientific name, which precisely calibrates the structure of its molecules and the composition of its elements. However, in the industry, people also call it by another name, which is the so-called synonym. This synonym either originated from the beginning of research or gradually became a common name due to the characteristics of the process.
As for the trade name, it is the name given by the merchant for it to be put on the market. This name is not only related to the characteristics of the substance, but also involves commercial considerations. Either take the excellence of its efficacy, or recognize its extraordinary quality, in order to attract the eyes of the audience and sell widely.
From this perspective, the synonym of "1,2,4-trifluoro-5-iodobenzene" and the trade name, in the forest of chemical industry, each has its own use, complementing each other, and drawing the picture of the chemical industry together.
Safety & Operational Standards
About 1,2,4-trifluoro-5-iodobenzene product safety and operating specifications
Fu 1,2,4-trifluoro-5-iodobenzene is an important substance in chemical research. When it is experimentally operated and used, safety and regulations are the top priority.
In terms of safety, this substance may have certain chemical activity and potential hazards. Store it in a cool, dry and well-ventilated place, away from fire, heat and oxidants. If it is not stored properly, it may cause chemical changes and cause danger.
As for the operating specifications, the experimenter should wear appropriate protective equipment, such as laboratory clothes, gloves and goggles. When operating, it should be carried out in a fume hood to ensure that harmful gases are discharged in time to avoid inhalation and damage to health. When taking it, use an accurate measuring tool and use it according to the amount required by the experiment. Do not increase or decrease it at will, so as not to affect the experimental results and avoid waste.
If you accidentally come into contact with this substance, those who come into contact with the skin should be rinsed with a large amount of flowing water immediately. If you still feel unwell, you need to seek medical attention immediately. If you come into contact with the eyes, you need to rinse with a large amount of water immediately and seek professional medical assistance quickly.
Furthermore, the waste generated during the experiment should not be discarded at will. It should be properly disposed of in accordance with the chemical waste treatment specifications to prevent environmental pollution.
In general, the research and use of 1,2,4-trifluoro-5-iodobenzene must adhere to safety and operating standards in order to ensure the smooth progress of the experiment and ensure the safety of personnel and the environment.
Application Area
The author of "Mengxi Written Talks" is also a talk on ancient science and technology. Today, as a chemical researcher, imitate its body and discuss the application field of Benzene, 1,2,4 - Trifluoro - 5 - Iodo - products.
This compound has great potential in pharmaceutical research and development. Its unique structure can accurately fit specific biological targets, or can help create new specific drugs and cure difficult diseases. In materials science, it can also be used as a key component of functional materials, improve material properties, improve its electrical and optical properties, and be used in high-end electronic devices. In agricultural chemistry, it can create the cornerstone for new pesticides. With its chemical activity, it can effectively repel insects and prevent diseases, protect the flourishing of crops, and ensure the prosperity of harvests. All these show the broad application prospects of Benzene, 1, 2, 4 - Trifluoro - 5 - Iodo - products in many fields.
Research & Development
In recent years, I have studied chemical substances, and obtained Benzene, 1,2,4-Trifluoro-5-Iodo-. This substance is also unique in nature and widely used. I wanted it, so I devoted myself to its research.
At first, I studied its structure and analyzed its components to clarify its chemical properties. Then I tried various methods to make it, observed the conditions of the reaction, and sought the best yield. Although the process is difficult and encountered obstacles repeatedly, I have not changed my mind.
After months of research, I have gradually gained experience in its preparation. The obtained product is of high quality and quantity. And think this product is available in the fields of medicine and materials. In the future, I will go deeper and explore its uses widely, hoping to create something that will benefit people's livelihood and promote the progress of chemical industry. This is my wish.
Toxicity Research
Studies on the toxicity of 1,2,4-trifluoro-5-iodobenzene
The chemical properties of benzene are often seen in various compounds. Today, there are 1,2,4-trifluoro-5-iodobenzene. The study of its toxicity is related to the health of all living beings and the safety of the environment, which cannot be ignored.
Observe the structure of its molecules. Atoms of fluorine and iodine are attached to the benzene ring, or cause their properties to be different. Taste the test of toxicity, or apply it to all kinds of living things to identify its harm. In microbial bodies, observe the changes in their growth and reproduction; in the body of animals, observe the state of their physiological functions, such as the damage of organs and the difference in behavior.
However, the judgment of toxicity depends not only on its harm to living beings, but also on the return of the environment. This thing is in nature, or difficult to degrade, accumulates in water and soil, enters the biological chain, and gradually accumulates, which is a big problem in the end. Therefore, when studying its toxicity, we should apply all methods and investigate it carefully, so that we can actually get it, and think that it is the foundation for preventing problems before they occur.
Future Prospects
Benzene, 1, 2, 4 - Trifluoro - 5 - Iodo - This object has emerged in today's chemical research. Looking at its future prospects, it is quite a grand way.
Its unique nature may open up new frontiers in various fields. Medicine together may be a special agent that can assist in the research of special effects, treat diseases, relieve people's diseases, and save people from diseases. The field of materials can be made into extraordinary materials, with excellent performance, suitable for various instruments, making the equipment delicate and durable.
Although there may be thorns in the road ahead, with the perseverance and wisdom of our generation of chemical researchers, we will be able to overcome them. With time, in-depth investigation, we will make Benzene, 1, 2, 4 - Trifluoro - 5 - Iodo - make the best use of it, for the progress of the world and the well-being of the people, glow and show wonders, unfolding unprecedented grandeur, and opening a new chapter in the future.
Where to Buy Benzene, 1,2,4-Trifluoro-5-Iodo- in China?
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Frequently Asked Questions

As a leading Benzene, 1,2,4-Trifluoro-5-Iodo- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1,2,4-trifluoro-5-iodobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%9F-5-%E7%A2%98%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%EF%BC%9A
This substance is light yellow to colorless and transparent. Under normal temperature and pressure, it is often a flowing liquid, which is clear and free of impurities. Its smell is slightly fragrant, but it is not rich and pungent, but a milder and more acceptable smell.
When it comes to density, compared with common water, the density of this substance is slightly lower. If placed in water, it can slowly float on the water surface, just like a light boat above the blue waves. Its boiling point is also not high, and under appropriate heating conditions, it is easier to boil and turn into a gas state. When heated to the boiling point, it can be seen that fine bubbles quickly rise inside, such as pearl jade rising, and then turn into curling steam.
In terms of solubility, it can be well miscible with many organic solvents, just like water emulsion, difficult to distinguish from each other. However, its solubility in water is relatively limited, only a little can be dissolved, most of the time, dripping into water, it is like oil dripping into soup, will be layered with water, each maintaining its own form.
Its volatility is relatively considerable, and it is left standing in an open container. It can be seen that its amount gradually decreases over time, just like quietly disappearing into the invisible. Under light, its stability is acceptable, and generally does not change significantly due to ordinary light exposure. It is like a gentleman who is undeterred, facing external disturbances safely.
The conductivity of this substance is very small, almost an insulator. When connected to a simple conductive circuit, it is difficult to make current pass through, like a barrier that blocks current. And under normal chemical reaction conditions, it has a certain chemical stability, and it is not easy to react violently with common substances. Like a calm and restrained person, it does not easily reveal its own activity.
What are the chemical properties of 1,2,4-trifluoro-5-iodobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%9F-5-%E7%A2%98%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%EF%BC%9A
This compound has certain stability, and its structure contains specific atoms and chemical bonds. In terms of physical properties, it is normal or solid, with specific melting points and boiling points, and has certain solubility in specific solvents. From the perspective of chemical activity, it shows unique reactivity due to specific functional groups.
In the nucleophilic substitution reaction, due to the distribution of specific atoms and surrounding electron clouds in its structure, it can be replaced with nucleophilic reagents. If the nucleophilic reagent has high activity, the reaction may occur more easily, and new compounds are formed. In the redox reaction, it is different from the oxidizing agent and reducing agent encountered according to the reaction conditions, or oxidizing or reducing. When encountering strong oxidizing agents, the molecular internal chemical bonds or breaks, and oxidation reactions occur to generate products containing more oxygen atoms.
In the field of organic synthesis, 1%2C2%2C4-%E4%B8%89%E6%B0%9F-5-%E7%A2%98%E8%8B%AF%E7%9A%84 can be used as a key intermediate to construct complex organic molecular structures through a series of reactions. The positions and properties of functional groups in its structure provide various possibilities for the design of synthetic routes. Chemists can skillfully use its chemical properties according to the needs of the target product, and gradually react to achieve the expected synthesis target.
What are the main uses of 1,2,4-trifluoro-5-iodobenzene?
1,2,4-Triethyl-5-chloropyridine is a key compound in the field of organic synthesis. Its main uses are roughly as follows.
First, it plays an important role in the creation of pesticides. The unique chemical structure of 1,2,4-triethyl-5-chloropyridine endows it with outstanding biological activity. Using this as a starting material, a variety of high-efficiency pesticides can be prepared through a series of delicate chemical reactions. For example, some new insecticides, by interfering with the nervous system or physiological and metabolic processes of pests, show excellent killing effects on common crop pests, such as aphids, borers, etc., and have a relatively slight impact on the environment, which can effectively maintain the balance of agricultural ecology and ensure the harvest of crops.
Second, it also has outstanding performance in the field of pharmaceutical research and development. Scientists have found that based on this compound, by modifying and modifying its molecular structure, drug intermediates with specific pharmacological activities can be obtained. After further synthesis and optimization of such intermediates, it is expected to develop therapeutic drugs for specific diseases. For example, in the exploration of anti-tumor drugs, compounds derived from 1,2,4-triethyl-5-chloropyridine have a certain inhibitory effect on the growth and proliferation of some tumor cells, providing a new idea and direction for the research and development of anti-cancer drugs.
Third, in the field of materials science, 1,2,4-triethyl-5-chloropyridine has also emerged. Due to its unique electron cloud distribution and chemical stability, it can participate in the preparation of polymer materials with special properties. For example, introducing it into the polymer molecular chain can improve the thermal stability, mechanical properties, and electrical properties of the material, thus expanding the application scope of polymer materials in high-end fields such as aerospace and electronics.
What are the synthesis methods of 1,2,4-trifluoro-5-iodobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%9F-5-%E7%A2%98%E8%8B%AF%E7%9A%84%E5%90%88%E6%88%90%E6%96%B9%E6%B3%95%E5%A4%9A%E7%A7%8D%E5%A4%9A%E6%A0%B7, one of the methods is described below for your reference.
You can first take diethyl malonate and bromoethane, in an alcohol solution of sodium alcohol, perform nucleophilic substitution reaction to obtain a substituted diethyl malonate. Following hydrolysis of potassium hydroxide solution, after acidification and heat decarboxylation, a corresponding carboxylic acid can be obtained.
Then start with propylene, add it to hydrogen bromide to obtain 2-bromopropane. React it with magnesium chips in anhydrous ether to make Grignard's reagent.
Let the above-obtained carboxylic acid react with thionyl chloride and convert it into an acid chloride. After the acid chloride reacts with Grignard's reagent and hydrolyzes, 1%2C2%2C4-%E4%B8%89%E6%B0%9F-5-%E7%A2%98%E8%8B%AF can be obtained.
In addition, there are other methods. If a suitable halogenated aromatic hydrocarbon and a corresponding allyl-containing reagent are used under the catalysis of palladium, a coupling reaction can be carried out, and then a series of modifications can be carried out to achieve the synthesis of the target product. Or it is feasible to construct a cyclic compound containing the target carbon skeleton first, and then go through the steps of ring opening and functional group conversion. The way of synthesis depends on various factors such as the availability of raw materials, the difficulty of reaction, and the high or low yield.
What are the precautions for storing and transporting 1,2,4-trifluoro-5-iodobenzene?
1% 2C2% 2C4-tribromo-5-chlorotoluene is also an organic compound. When storing and transporting, many precautions need to be kept in mind.
First, when storing, look for a cool, dry and well-ventilated place. This compound is more sensitive to heat. If it is in a high temperature environment, it may cause decomposition, deterioration, and even dangerous chemical reactions. Therefore, the warehouse temperature should be controlled within a suitable range to prevent accidents caused by excessive temperature.
Second, because it is toxic and corrosive to a certain extent, it must be stored separately from oxidants, acids, bases and other substances. These substances come into contact with it, or cause violent chemical reactions, causing serious accidents such as fires and explosions. And it is necessary to keep away from fire and heat sources to prevent open flames and static electricity to ensure storage safety.
Third, the transportation process should not be ignored. The packaging must be tight and reliable to ensure that there is no risk of leakage during transportation bumps. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment, just in case. Transport personnel should also be familiar with the characteristics of the compound and emergency treatment methods, and pay close attention to the condition of the goods on the way, such as whether the packaging is damaged, whether there is any abnormal smell, etc.
Fourth, storage and transportation places should be equipped with clear and clear warning signs to inform others that this is a dangerous chemical and not to touch it, so as to arouse everyone's vigilance and avoid accidents. All of these are the key to ensuring the safe storage and transportation of 1% 2C2% 2C4-tribromo-5-chlorotoluene, and caution is required.