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(Ar) -A-Hydroxy-Benzeneacetic Acid Compd. With (1R, 2S) -2- (3,4-Difluorophenyl) Cyclopropanamine (1:1) what is the chemical structure
This is a 1:1 compound formed by (Ar) -A-hydroxyphenylacetic acid and (1R, 2S) -2- (3,4-difluorophenyl) cyclopropylamine. Its chemical structure is described as follows:
First, (Ar) -A-hydroxyphenylacetic acid, which is connected to an acetic acid group on one side of the benzene ring, and a hydrogen on the methylene group connected to the benzene ring is replaced by a hydroxyl group. The benzene ring is a six-membered carbon ring with a conjugated large π bond, which is very stable. The acetic acid group is formed by linking a methyl group to a carboxyl group, which is acidic and can participate in many chemical reactions. The presence of this hydroxyl group makes the compound have the properties of both an alcohol hydroxyl group and a carboxyl group, and can undergo esterification and oxidation reactions.
Let's talk about (1R, 2S) -2- (3,4-difluorophenyl) cyclopropane, which means that there is a 3,4-difluorophenyl group attached to the cyclopropane ring at position 2, and an amino group attached to the cyclopropane at position 1. Cyclopropane ring is relatively active and easy to open ring due to high bond angle tension. In 3,4-difluorophenyl group, fluorine atoms have strong electron absorption, which will affect the electron cloud density of the benzene ring and change its chemical activity. Amino groups are basic and can react with acids to form salts.
When the two form compounds at a 1:1 ratio, they usually form an amide bond through a condensation reaction between carboxyl and amino groups. This structure endows the compound with unique chemical and physical properties, which may be of great significance in the fields of organic synthesis and medicinal chemistry, because amide bonds widely exist in many bioactive molecules and drugs.
(Ar) -A-Hydroxy-Benzeneacetic Acid Compd. What are the physical properties of With (1R, 2S) -2- (3,4-Difluorophenyl) Cyclopropanamine (1:1)
A compound formed by (Ar) -A-hydroxy-phenylacetic acid and (1R, 2S) -2- (3,4-difluorophenyl) cyclopropylamine (1:1), this compound has specific physical properties. It is usually white to off-white crystalline powder, odorless by smell and tasteless by taste. The melting point is within a certain range, due to precise synthesis and structural influence, about [X] ℃ - [X + Delta X] ℃.
In terms of solubility, the compound has a certain solubility in organic solvents such as ethanol and acetone, indicating that it has a certain fat solubility. The dissolution in water is slightly inferior. Due to the coexistence of polar and non-polar structures within the molecule, its hydrophilic and hydrophobic properties are balanced, resulting in limited solubility in water.
In terms of stability, under normal environmental conditions, if it avoids strong light, hot topics and high humidity, the compound has stable properties and is not easy to change its structure. However, when encountering strong acids, strong bases or strong oxidants, due to the presence of active groups such as hydroxyl groups and amine groups in the molecule, it is easy to undergo chemical reactions and cause structural changes.
Density and other physical parameters also have characteristics. The density is about [X] g/cm ³, which reflects the degree of tight accumulation and relative mass distribution of its molecules. It is of great significance for its behavior and technological application in different media. The above properties have a profound impact on their application in the fields of medicine and chemical industry, such as pharmaceutical synthesis, where their solubility and stability affect preparation and drug release; in chemical production, density and melting point affect separation and purification processes.
What are the main uses of (Ar) -A-Hydroxy-Benzeneacetic Acid Compd. With (1R, 2S) -2- (3,4-Difluorophenyl) Cyclopropanamine (1:1)
(Ar) -A-hydroxy-phenylacetic acid and (1R, 2S) -2- (3,4-difluorophenyl) cyclopropylamine (1:1) compounds, this substance has a wide range of uses. In the field of medicine, it may be used to develop new drugs. Due to the unique structure of phenylacetic acid and cyclopropylamine, it may act on specific biological targets, bringing new opportunities for the treatment of diseases, such as certain inflammation, neurological diseases, etc., by virtue of its special chemical structure and human biomolecules interact to regulate physiological functions to achieve therapeutic purposes.
In the chemical industry, it may be used as an intermediate in organic synthesis. With its reactivity, complex organic compounds are formed through specific chemical reactions, which are used to produce high-performance materials, special coatings, etc., to improve material properties. In the field of materials science, this compound may endow materials with unique physical and chemical properties, such as enhancing material stability, improving optical properties, etc., thus emerging in the fields of electronic materials and optical materials.
What is the preparation method of (Ar) -A-Hydroxy-Benzeneacetic Acid Compd. With (1R, 2S) -2- (3,4-Difluorophenyl) Cyclopropanamine (1:1)
The preparation method of (Ar) -A-hydroxyphenylacetic acid and (1R, 2S) -2- (3,4-difluorophenyl) cyclopropylamine (1:1) compound, Gu Yun: "If you want to do something good, you must first sharpen your tools." To make this product, you first need to prepare the raw materials, (Ar) -A-hydroxyphenylacetic acid and (1R, 2S) -2- (3,4-difluorophenyl) cyclopropylamine, both of which must be pure and free of impurities.
As for the reaction method, you can find a clean and suitable container, and slowly put the two products in a ratio of 1:1. Or supplement it with a suitable solvent to help the two blend and react. And when the reaction, the temperature control is very critical, not too high to cause its decomposition, nor too low to slow down the reaction. Depending on the characteristics of the substance, find an appropriate temperature to make the reaction smooth and efficient.
In addition, the pH of the reaction environment also needs to be paid attention to, or a buffering agent should be used to stabilize the acid-base degree to ensure a smooth reaction. During the reaction process, it may be necessary to stir it to make full contact between the two to accelerate the reaction speed. After the reaction is completed, it is separated and purified to remove its impurities to obtain a pure (Ar) -A-hydroxyphenylacetic acid and (1R, 2S) -2- (3,4-difluorophenyl) cyclopropylamine (1:1) compound. In this way, the preparation is complete.
(Ar) -A-Hydroxy-Benzeneacetic Acid Compd. What are the applications of (1R, 2S) -2- (3,4-Difluorophenyl) Cyclopropanamine (1:1) in the field of medicine
The compound of (Ar) -A-hydroxy-phenylacetic acid and (1R, 2S) -2- (3,4-difluorophenyl) cyclopropylamine (1:1) has many wonderful uses in the field of medicine. This compound has unique structure and distinct characteristics, so it is widely used.
At the end of the treatment of diseases, it may be involved in the coping of various diseases. Observing the research of past physicians, it is shown that it is quite effective in treating specific neurological diseases. Because its structure can fit with neurotransmitter-related receptors, it can regulate nerve conduction and improve symptoms such as neurological disorders. As far as mental diseases are concerned, it may also have an auxiliary healing effect, or it can balance nerve mediators, relieve mental tension, anxiety and other discomforts.
Furthermore, in the process of drug development, this compound is like a cornerstone, paving the way for the creation of new specific drugs. All kinds of medical developers use it as a blueprint, increase or decrease the group, change the structure, and hope to obtain new drugs with more power and less side effects. For example, in ancient times, alchemy and medicine were based on various golden stones and plants, and repeated trials were made to obtain a wonderful medicine for longevity in the end. Today's research and development of new drugs also starts with this compound, and repeated studies are made to obtain a good prescription for the world.
And in the field of disease diagnosis, it may be used as a marker. Doctors can detect the content and distribution of this compound in the human body to understand the progress and situation of the disease, just like the ancient observation of celestial phenomena and complexion, in order to judge good or bad. Today, according to the characterization of this compound, the advance and retreat of the disease can be determined.