A-Amino-4-Fluorobenzeneacetic Acid

Hongda Chemical

Specifications

HS Code	682972
Chemical Formula	C8H8FNO2
Molar Mass	169.153 g/mol
Appearance	Solid
Melting Point	N/A
Boiling Point	N/A
Solubility In Water	N/A
Solubility In Organic Solvents	N/A
Pka Value	N/A
Density	N/A
Flash Point	N/A

As an accredited A-Amino-4-Fluorobenzeneacetic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of α -amino - 4 - fluorobenzeneacetic acid packaged in a sealed plastic bag.
Storage	Storage of α -amino-4 -fluorobenzeneacetic Acid α -amino-4 -fluorobenzeneacetic acid should be stored in a cool, dry place. Keep it away from heat sources, direct sunlight, and moisture. Store in a tightly sealed container to prevent exposure to air, which could potentially lead to oxidation or degradation. It is also advisable to store it separately from incompatible substances to avoid chemical reactions.
Shipping	"A -amino - 4 - fluorobenzeneacetic Acid" is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transportation regulations, ensuring proper handling to prevent spills and maintain product integrity during transit.

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General Information

Historical Development

A - Amino - 4 - Fluorobenzeneacetic Acid, the origin of this thing, few people knew at the beginning. Its research and development process seemed to be hidden in the clouds. However, as the years passed, many talented people devoted themselves to research.
In the initial stage, everyone explored the vast sea of knowledge, but was not discouraged by repeated setbacks. After countless experiments, from the selection of raw materials to the exploration of reaction conditions, they all tried their best.
As the research got better and better, they gained more knowledge of its properties and synthesis methods. Chemists exchanged ideas with each other and continuously improved the process. Each breakthrough seemed to pave the foundation for its development.
Today, A-Amino-4-Fluorobenzeneacetic Acid has made a name for itself in the chemical industry. Its historical development is the result of the efforts of many researchers. There may still be a broader development field in the future, bringing more surprises to the academic and industrial circles.

Product Overview

Today there is a substance named A-Amino-4-Fluorobenzeneacetic Acid. This substance is unique in the field of chemistry. Its structure is exquisite, containing fluorine atoms and amino groups, adding a unique appearance to the structure of phenylacetic acid.
Looking at its properties, it has the properties of both acid and base. Amino groups can be combined with acids and fluorine atoms, and fluorine atoms are endowed with special physical and chemical activities. Because of its different structure, it is often a key raw material in the process of organic synthesis. It can lead the reaction direction and obtain unique products.
In the pharmaceutical industry, it has also made a name for itself. Or as a lead compound, modified and modified, it is expected to become a good medicine for treating diseases and saving people. In the field of material science, it can participate in the polymerization reaction to produce materials with special properties. This A-Amino-4-Fluorobenzeneacetic Acid, although microscopic, has great potential in various fields. We need to explore it in depth to develop its application.

Physical & Chemical Properties

A-Amino-4-Fluorobenzeneacetic Acid is a unique compound. Its physical and chemical properties are worth studying. Looking at its morphology, it is a white crystalline solid at room temperature, and the texture is relatively dense. Its melting point, which has been accurately determined, is within a certain range. This property can be a key basis for the identification and purification of compounds.
As for its solubility, it shows a unique tendency in common organic solvents. In solvents such as ethanol, it has a certain solubility, but in water, the solubility is different. These solubility properties are closely related to the structure of its molecules. Its chemical properties are also interesting because the molecules contain specific functional groups, which enable them to participate in a variety of chemical reactions and may have important uses in the field of organic synthesis. The comprehensive investigation of its physical and chemical properties is of great significance for further understanding the essence of this compound and expanding its application range.

Technical Specifications & Labeling

Nowadays, the substance of A-Amino-4-Fluorobenzeneacetic Acid is crucial to its technical specifications and identification (product parameters). Its technical specifications need to be precise and clear, such as the proportion of ingredients and the level of purity. In terms of identification, from the accuracy of the name to the labeling of various parameters, there should be no difference. If this product is to be used well, the technical specifications must be suitable for practical needs, and the labeling must be clear at a glance, so that the user can operate it without error and achieve the expected effect. In this way, the essence of the technical specifications and labeling of this product lies.

Preparation Method

The preparation of A-amino-4-fluorophenylacetic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is quite critical, and fluorobenzene-containing compounds and specific amino reagents are the most important. In the production process, fluorobenzene is first halogenated and halogen atoms are introduced. This is the key starting step.
Then, it reacts with amino reagents in a specific ratio, at a suitable temperature and pressure to form a preliminary intermediate. After a series of purification and separation steps, impurities are removed.
The reaction steps need to be precisely regulated, and temperature, time and the proportion of reactants are all key points. If the temperature is too high during halogenation, side reactions are frequent; the amination reaction time is insufficient, and the product is impure. The catalytic mechanism of
cannot be ignored, and the selection of high-efficiency catalysts can improve the reaction rate and yield. Such as specific metal complex catalysts, the activation energy of the reaction can be reduced, making the reaction easier to proceed. After this series of operations, a relatively pure A-amino-4-fluorophenylacetic acid product can be obtained.

Chemical Reactions & Modifications

The reaction and modification of A-Amino-4-Fluorobenzeneacetic Acid are very important in chemical research. Looking back at the past, the evolution of chemistry depends on the study of the reaction characteristics of various substances.
The reaction of A-Amino-4-Fluorobenzeneacetic Acid may involve the breaking and recombination of chemical bonds. The way to modify it can be obtained by changing chemical reagents, temperature and pressure. For example, using suitable reagents or inducing changes in their functional groups to achieve specific chemical properties.
However, there are also difficulties in this. The precise control of reaction conditions is related to the purity and yield of the product. When modifying, it is also necessary to consider the stability of the molecular structure, so as not to make it counterproductive. Therefore, chemists should explore repeatedly with a rigorous state, observe the reaction mechanism in detail, and find ways to optimize, so that A-Amino-4-Fluorobenzeneacetic Acid can be used in various fields and contribute to the progress of chemistry.

Synonyms & Product Names

Today there is a thing called A-Amino-4-Fluorobenzeneacetic Acid. This thing is widely used in the field of chemistry. There are many synonyms, either by nature or by structure.
In the industry, people also use various trade names. These synonyms and trade names are all for the convenience of industry communication and research. Its synonyms are commonly used in academic seminars to accurately describe the properties of the substance; trade names are more used in market circulation to show the uniqueness of the product.
If you want to explore it in detail, you can find many relevant records in various chemical classics and research reports. From the beginning of its discovery to the expansion of its application, there are traces to follow. Therefore, knowing its synonyms and trade names is of great significance in studying this object and promoting the development of its related industries.

Safety & Operational Standards

Safety and Operation Specifications of A - Amino - 4 - Fluorobenzeneacetic Acid
Husband A - Amino - 4 - Fluorobenzeneacetic Acid is also an important product in chemical research. During its experiment and application, safety and operation standards are of the utmost importance and cannot be ignored.
First word safety. This object may have certain chemical activity, and it must be strictly protected when it is in contact. When handling, use suitable protective equipment, such as gloves, goggles, etc. Gloves should be selected with good chemical resistance to prevent them from contacting the skin and avoid skin invasion and discomfort or damage. The goggles can protect the eyes from accidental splashing and ensure the safety of eyesight.
Furthermore, the operating environment cannot be ignored. When it is well ventilated, it is necessary to prevent the accumulation of volatile gas, which will deteriorate the air quality and endanger the health of the operator. If necessary, it is also necessary to have appropriate ventilation equipment, such as fume hoods, etc., to promote the circulation of gas and dissipate harmful gas.
Times and operating specifications. When using this object, it should be measured with a precise instrument, and it should not be rough. When weighing, the accuracy of the balance must meet the requirements to ensure the accuracy of the dosage. The process of dissolution or reaction, the rate and conditions must be strictly controlled. Temperature, pH and other factors can affect its chemical properties and reaction results. For example, when heating, the size of the heat and the length of time should be carried out according to the requirements of the experiment, and no claims should be made.
After the reaction is completed, the residue should not be disposed of at will. When disposed of according to the prescribed method, or recycled, or neutralized, or otherwise disposed of properly, so as not to pollute the environment and leave behind disasters in future generations.
In short, in the management of A-Amino-4-Fluorobenzeneacetic Acid, safety is the basis and norms are the most important. Only by following these two can the purpose of research be achieved, and the body can be kept safe and clear without worries.

Application Area

A - Amino - 4 - Fluorobenzeneacetic Acid is also a chemical substance. Its use, in the field of, can be made of raw materials. This compound can be used for the synthesis of multiple compounds, or it can assist in the research and development of new diseases, such as pain and inflammation. In the field of, it also has its use. It can be the basis of synthesis, help to prevent disease, crop development, to ensure prosperity. And in the field of material science, it may be able to help with the research of new materials, material with special, increase its performance, so that all industries can have a good performance. All these specifications are in the field of application of A - Amino - 4 - Fluorobenzeneacetic Acid.

Research & Development

I have been studying A - Amino - 4 - Fluorobenzeneacetic Acid for many years. At the beginning, I explored the method of its preparation, but I had no idea, and I tried and failed repeatedly. However, I did not change my mind, and I studied day and night.
After months of work, I finally got something. Optimize the reaction conditions and adjust the ratio of raw materials to gradually increase the yield. Looking at its properties, this compound has unique activity and may be useful in the field of medicine.
I also think about its future development. If I can explore it in depth, improve the process, and reduce costs, it will definitely be widely available in the world. With time, it may benefit all living beings. This is my grand wish. Although we have achieved success today, we should continue to study hard and do our best for its research and development.

Toxicity Research

A - Amino - 4 - Fluorobenzeneacetic Acid is the key to the toxicity study of this chemical. Looking at the methods of exploring toxicants in the past, the first step is to analyze its chemical structure, explain its molecular combination and characteristics, and infer the beginning of toxicity.
Then, apply animal experiments. Select several animals and give them this product to observe their physiological abnormalities, changes in behavior, and organ damage. Detail the changes in eating, activity, and physical signs, and expect toxic reactions.
Complex with cell experiments, take different cell lines, and add this chemical to measure cell viability, proliferation, and apoptosis. Insight into its impact on the microscopic level of cells, and clarify the mechanism of toxicity. The toxicity of A - Amino - 4 - Fluorobenzeneacetic Acid can be determined by this number method, so as to provide evidence for its application and protection, avoid its harm and promote its benefits, and protect the environment and personal safety.

Future Prospects

Today, A - Amino - 4 - Fluorobenzeneacetic Acid is the result of our generation's painstaking research. Although it is still in the state of research, we are full of hope for its future development.
This compound has unique properties and has potential uses in various fields such as medicine and chemical industry. With time, through in-depth investigation and repeated trials, it may be able to reveal more mysteries and develop new effects.
In the field of medicine, it may be the foundation for creating new drugs and curing various difficult and complicated diseases; in the field of chemical industry, it may be able to optimize production techniques and improve product quality. We must do our best and study it, hoping to turn this achievement into practical benefits, for the well-being of future generations, and for the world. In the future, A-Amino-4-Fluorobenzeneacetic Acid will surely shine and open a new chapter.

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Frequently Asked Questions

As a leading A-Amino-4-Fluorobenzeneacetic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of A-Amino-4-Fluorobenzeneacetic Acid?

A-amino-4-fluorophenylacetic acid, this is an organic compound. It has a wide range of uses and is often a key intermediate in the field of medicinal chemistry.
The history of Guanfu Pharmaceutical's research and development, the creation of many drugs, relying on this compound as the starting material, through complex chemical reactions, adding functional groups, shaping the specific configuration of molecules, to form drugs with specific pharmacological activities. Because of the presence of amino groups and fluorine atoms in its structure, it can significantly affect the physical and chemical properties and biological activities of molecules, so it can endow the prepared drugs with unique effects.
In the field of pesticide chemistry, there are also traces. Pesticide molecules constructed on its basis may have high insecticidal and bactericidal properties. The characteristics of Gain amino and fluorine atoms can precisely bind them to specific targets in pests or pathogens, interfering with their normal physiological and metabolic processes, so as to achieve the purpose of preventing pests and diseases.
Furthermore, in the field of organic synthetic chemistry, A-amino-4-fluorophenylacetic acid, as an important intermediate, can facilitate the synthesis of various complex organic compounds. Chemists can achieve precise regulation of the structure and function of the target product by ingenious modification of its structure, expand the types and properties of organic compounds, and promote the progress and development of organic synthetic chemistry.
This compound plays an indispensable role in many fields such as medicine, pesticides, and organic synthesis, and has far-reaching impact on the development of related industries.

What are the chemical properties of A-Amino-4-Fluorobenzeneacetic Acid?

A-amino-4-fluorophenylacetic acid, this is an organic compound. Its physical properties are mostly white crystalline powders at room temperature, with a certain melting point, about [X] ° C, depending on purity and test conditions. It has a certain solubility in water, which can be based on the principle of similar miscibility. Its molecular structure contains polar groups, so it has a certain solubility in polar solvent water, and it has good solubility in organic solvents such as ethanol and acetone.
Its chemical properties are active, and amino groups can participate in many reactions. If it reacts with acid to form a salt, in the case of hydrochloric acid, amino nitrogen atoms provide lone pairs of electrons, which combine with hydrogen ions to form corresponding salts. And the amino group has nucleophilic properties, and can undergo nucleophilic substitution reaction with halogenated hydrocarbons. Halogen atoms in halogenated hydrocarbons are replaced by amino groups to form new nitrogen-containing compounds.
The benzene ring part also has unique chemical properties. Because the benzene ring has a conjugated large π bond, it has certain stability and is prone to electrophilic substitution reaction. If under appropriate conditions, bromine reacts with bromine, bromine atoms replace hydrogen atoms on the benzene ring.
The carboxyl group properties cannot be ignored. It is acidic and can neutralize with bases to form corresponding carboxylic salts and water. It can also undergo esterification reaction with alcohols. Under acid catalysis, carboxyl groups and alcohol hydroxyl groups are dehydrated and condensed to form ester compounds.
In addition, although the fluorine atom in this compound is relatively stable, it can also participate in the reaction under specific strong reaction conditions, affecting the overall chemical activity and reaction selectivity of the molecule.
This compound is widely used in the field of organic synthesis and can be used as a pharmaceutical intermediate for the synthesis of various drugs; in materials science, with appropriate modification, it can be used to prepare materials with special properties.

What is the production process of A-Amino-4-Fluorobenzeneacetic Acid?

The process of making A-amino-4-fluorophenylacetic acid is quite delicate, and it requires several materials and a series of wonderful methods to obtain it.
First, 4-fluoroacetophenone needs to be prepared, which is the key starting material. Take an appropriate amount of 4-fluoroacetophenone, place it in a reactor, add hydroxylamine hydrochloride, and add an appropriate amount of sodium acetate as an aid. At a suitable temperature, about 60 to 80 degrees Celsius, let it react, which takes about 3 to 5 hours. This step aims to make 4-fluoroacetophenone react with hydroxylamine hydrochloride to obtain 4-fluoroacetophenone oxime. The reaction principle is that the amino group in the hydroxy amine hydrochloride interacts with the carbonyl phase of 4-fluoroacetophenone to form the structure of oxime.
When 4-fluoroacetophenone oxime is obtained, move to another clean kettle, add an appropriate amount of concentrated sulfuric acid, slowly heat up to 120 to 140 degrees Celsius, and continue the reaction for about 2 to 3 hours. This step is a Beckmann rearrangement reaction. Under the action of concentrated sulfuric acid, the molecular structure of 4-fluoroacetophenone oxime is rearranged to obtain 4-fluoroacetaminophenone. Concentrated sulfuric acid here plays a catalytic role and promotes the rearrangement.
Treatment of 4-fluoro - α - acetaminophenone with sodium hydroxide solution. Dissolve an appropriate amount of sodium hydroxide in water, mix with 4-fluoro - α - acetaminophenone, control the temperature at 50 to 70 degrees Celsius, and react for about 2 to 3 hours. This is a hydrolysis reaction. The acetyl group of 4-fluoro - α - acetaminophenone is hydrolyzed to give 4-fluoro - α - acetaminophenone. Sodium hydroxide provides an alkaline environment for the hydrolysis reaction to facilitate its smooth progress.
4-fluoro- - α - aminophenylacetophenone is obtained, and then acidified. Add an appropriate amount of dilute hydrochloric acid and adjust the pH to the acidic range to convert 4-fluoro - α - aminophenylacetophenone into A-amino-4-fluorophenylacetic acid. After purification by extraction and crystallization, pure A-amino-4-fluorophenylacetic acid can be obtained. A suitable organic solvent can be selected for extraction, such as ethyl acetate, to separate the product from the reaction solution; the crystallization is based on its solubility characteristics, temperature control and solvent ratio control, so that the product crystallizes and precipitates, and the final product is good.

What is the price range of A-Amino-4-Fluorobenzeneacetic Acid in the market?

The price of "A-Amino-4-Fluorophenylacetic Acid" in the market is difficult to be certain. The price of this product often varies due to many reasons, such as the quality of the product, the amount of purchase, the fluctuation of market conditions and the difference in origin.
Looking at the past market, if the quality is high and the purchase volume is quite large, the price may be slightly lower when blocking trade; if the purchase quantity is small, only a little for research, etc., the price may be high. In the past, the price of this product per gram in the market was as low as a few dollars, but there were also special reasons that caused the price per gram to reach tens of dollars.
And the origin is different, and the price is also different. If the product is produced in a place with abundant supply and skilled craftsmanship, the price may be close to the people due to the controllable cost; if the origin is remote, the raw materials are rare, or the craftsmanship is complicated, the price will tend to be higher.
And the market supply and demand trend is also the key to the price. Strong demand and limited supply, the price will rise; on the contrary, if supply exceeds demand, the price will drop. Therefore, in order to know the exact price, it is necessary to carefully observe the current market situation, consult various suppliers, and compare their price, quantity, and quality to get a more accurate price.

What is A-Amino-4-Fluorobenzeneacetic Acid's Quality Standard?

A-amino-4-fluorophenylacetic acid, a key organic compound in the field of fine chemicals, is widely used in the pharmaceutical, pesticide and other industries. To ensure its high quality and stable performance in various application scenarios, it is essential to formulate strict Quality Standards. The following are the main Quality Standard details.
The first is the content determination, which is the core indicator to measure its quality. The content of A-amino-4-fluorophenylacetic acid, determined by high performance liquid chromatography (HPLC), should not be less than 98.0%. This high purity requirement is designed to ensure that it can accurately participate in the reaction when it is used as a key intermediate in pharmaceutical synthesis, and improve the efficiency and quality stability of drug synthesis. If the content does not reach the standard, there will be too many impurities, or the reaction by-products will increase, which will affect the activity and safety of the drug.
The second time is to check the relevant substances. The HPLC method is used to strictly monitor the impurities introduced in the production process, such as starting materials, intermediates and by-products. The area of a single impurity peak shall not be greater than 0.5% of the main peak area of the control solution, and the area of the total impurity peak shall not be greater than 1.0% of the main peak area of the control solution. Strict control of the impurity content is intended to avoid unknown adverse reactions of impurities in the subsequent use of the drug, and to ensure the
Then the appearance and properties. This product should be white to off-white crystalline powder, and it should have uniform color and no foreign matter. This intuitive standard can help to preliminarily judge the quality of its quality. If the color is abnormal or there is foreign matter mixed in, or it suggests that there is pollution or quality fluctuations in the production process.
Melting point is also an important indicator. Its melting point range should be in a specific range, such as [specific melting point range], with an allowable deviation of ± [X] ° C. The accurate determination of the melting point can verify its purity and crystal structure. The presence of impurities will cause the melting point to shift or the melting range to widen.
Moisture content cannot be ignored. Determination by Karl-Fischer method, the moisture content shall not be higher than [X]%. Excessive moisture may affect its chemical stability, causing adverse reactions such as hydrolysis, which in turn affects product quality and storage life.
Heavy metal content must comply with regulations. Determined by atomic absorption spectrometry, the total amount of heavy metals such as lead, mercury, and cadmium shall not exceed parts per million [X]. Due to the potential toxicity of heavy metal residues, strict restrictions on their content can ensure that they are not harmful to human body and the environment in pharmaceutical and pesticide applications.