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6-Bromo-2,3-Difluorobenzenemethanol

6-Bromo-2,3-Difluorobenzenemethanol

Hongda Chemical

Specifications

HS Code

489179

Chemical Formula C7H5BrF2O
Molecular Weight 223.015
Appearance Typically a solid (but appearance can vary based on purity and conditions)
Purity Can vary depending on production method, usually high - purity grades are available for research and some applications

As an accredited 6-Bromo-2,3-Difluorobenzenemethanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 6 - bromo - 2,3 - difluorobenzenemethanol packaged in a sealed, chemical - resistant bottle.
Storage 6 - bromo - 2,3 - difluorobenzenemethanol should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances. Store in a tightly closed container to prevent moisture absorption and evaporation. Label the container clearly. Avoid storing near oxidizing agents or strong acids to prevent potential reactions.
Shipping 6 - bromo - 2,3 - difluorobenzenemethanol is shipped in well - sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit, following all relevant chemical shipping regulations to ensure safety.
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6-Bromo-2,3-Difluorobenzenemethanol 6-Bromo-2,3-Difluorobenzenemethanol
General Information
Historical Development
The chemical industry is changing with each passing day, and all kinds of compounds are emerging one after another. Today there is a thing called 6 - Bromo - 2,3 - Difluorobenzenemethanol. At the beginning of its birth, it only existed in the imagination of scholars, and everyone did not know its details.
At that time, Zhu Xian worked hard and tried hard on the experimental platform. After countless changes in the ratio and the adjustment of the reaction conditions, the initial form of this compound was obtained.
At the beginning, the preparation was difficult and the yield was very small. However, the researchers were reluctant to give up and worked tirelessly to improve the process. Or find new reagents, or explore other reaction paths. Years have passed, the process has advanced, and its output has gradually increased, and its purity has also increased.
From this perspective, 6 - Bromo - 2,3 - Difluorobenzenemethanol has become a non-negligible existence in the chemical industry since the beginning, and its development process is a witness to the diligent research of the academic community.
Product Overview
6-Bromo-2,3-difluorobenzyl alcohol is also a chemical developed by me. Its unique nature is a white crystalline solid with a specific melting boiling point, which is slightly soluble in organic solvents. The structure of this product is exquisite, with 6 bromine atoms, 2 and 3 fluorine atoms, and methanol groups connected to the benzene ring, co-forming its chemical structure.
The preparation method requires a multi-step reaction. Starting with a specific halogenated aromatic hydrocarbon, it goes through several processes such as halogenation and substitution, during which the reaction conditions are severe, and the temperature and pH need to be precisely controlled to obtain this high-purity product.
It has a wide range of uses in the field of organic synthesis, and can be used as a key intermediate to prepare many bioactive compounds, or to develop its important functions in the development of new drugs and functional materials. We should continue to study it to expand its application and contribute to the development of chemistry.
Physical & Chemical Properties
6 - Bromo - 2,3 - Difluorobenzenemethanol, the chemical material is also. Its physical property, color or color, often under the solid, with a specific degree of melting boiling. The melting is in a certain degree, depending on the degree of precision. Its boiling is also determined, reflecting the force of the molecule.
In terms of chemical properties, the bromine and fluoro alcohol groups in this compound exhibit their own properties. Bromine activity, can be substituted by the reverse, in case of nucleus, easy to replace, with other groups. Fluorine, low performance, influence the molecular properties, and its chemical properties are low. Alcohol groups can be esters of acids, or oxidized.
In the study of chemistry, it is an important part of the synthesis of new and special materials due to its physicality, and it is indispensable in the field of synthesis.
Technical Specifications & Labeling
6 - Bromo - 2,3 - Difluorobenzenemethanol is a unique compound. Its process specification and identification (product parameters) are the key. In the process specification, the reaction conditions, such as temperature, pressure, proportion of reactants, etc. The purity of the raw materials should not be ignored, so as to ensure purity, so as not to disturb the reaction process.
As for the identification, its physical properties should be detailed, such as color, state, taste, melting point, solubility and other parameters. Chemical properties should also be clearly marked to clarify their stability and reactivity. In this way, the compound can be used when its characteristics are known to everyone, used correctly, to ensure the safety and efficiency of production, and in the way of chemical research and development, in accordance with this process specification and labeling, it can reach a good state.
Preparation Method
Now want to make 6 - Bromo - 2,3 - Difluorobenzenemethanol this thing. The method of its preparation, the first need to specify the raw materials. Can be used 2,3 - difluorobromobenzene as the starting material, with paraformaldehyde, etc.
The process of making, first make 2,3 - difluorobromobenzene and magnesium chips in anhydrous ether, to form Grignard reagent. This step needs to be strictly controlled in anhydrous and oxygen-free environment, in order to prevent other responses. Second, slowly add the ether solution of paraformaldehyde dropwise, the temperature should be appropriate, not too high or too low, to promote its reaction. After finishing, hydrolyze with dilute acid to obtain crude products.
The reaction steps are carefully and orderly, forming Grignard first, then reacting with aldodes, and then hydrolyzing. As for the catalytic mechanism, magnesium helps to form Grignard reagents, increasing their activity and making nucleophilic attacks easy. Paraformaldehyde provides aldehyde groups and nucleophilic additions to Grignard reagents. Hydrolysis makes intermediates into targets. In this way, 6-Bromo-2,3-Difluorobenzenemethanol can be obtained.
Chemical Reactions & Modifications
Recent research 6 - Bromo - 2,3 - Difluorobenzenemethanol This substance has new results in the adaptation of chemistry. The initial reaction, the rate is not good, and the product is heterogeneous. The reason is that the cover conditions are not suitable, and the amount of reagent, the degree of temperature, and the time are all discretionary.
After changing the conditions, adjust the proportion of reagents, control the temperature to a suitable range, and increase the length of time. Then, the rate rises, and the purity of the product also advances. Looking at its properties, the structural changes make the physical and chemical properties different from before. This may be of great use in the field of synthesizing new compounds and drug research. Transform the response and nature, often variable and good, in order to achieve the required effect, the researcher should study carefully and try diligently.
Synonyms & Product Names
Today there is a thing called 6 - Bromo - 2,3 - Difluorobenzenemethanol. Although its name is complex, it is very important to my chemical researchers. The synonyms and trade names of this thing need to be studied in detail.
In the field of chemistry, there are many things, a common thing. Synonyms are derived from their chemical properties, structural characteristics, etc. Or according to their reaction characteristics, or according to their molecular composition, they are referred to as other names. Trade names are related to markets, uses, etc. In order to make products easy to recognize and sell, merchants often use concise and identifiable names.
6 - Bromo - 2,3 - Difluorobenzenemethanol, or according to its elemental composition, called bromofluorobenzyl alcohol class name; or because of its use, it has an exclusive trade name in a specific industry. Examining its synonyms and trade names in detail can help us better understand the status and application of this thing in academia and industry, and also facilitate communication and research.
Safety & Operational Standards
6 - Bromo - 2,3 - Difluorobenzenemethanol is a special chemical substance, and its safety and operating practices are of paramount importance in research and production.
All handling of this substance must be fully protective equipment. Protective clothing should be chemically resistant to resist the damage of this substance to the body; protective gloves should also be selected to ensure that there is no leakage when in contact with the substance, and to ensure the safety of the hands; goggles are used to protect the eyes from possible spills.
In the operating environment, ventilation conditions are essential. An effective ventilation system should be set up to make the air flow smoothly, disperse harmful gases that may escape in time, and reduce the concentration of this substance in the air to prevent damage to the human respiratory system. And the operation area should be kept clean and orderly to avoid the accumulation of debris, so as not to hinder the operation or cause accidents.
There are also strict requirements for storing this substance. When placed in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties, improper temperature and humidity may cause it to deteriorate, causing safety hazards. Different chemical substances should be stored in categories, and mixed storage is strictly prohibited to prevent mutual reaction.
During use, the operating specifications must be strictly observed. Accurate measurement and access to avoid waste and excessive use. After use, the access tools should be properly cleaned to prevent residual substances from contaminating other items. If any substances are accidentally spilled, clean them up immediately according to specific procedures, and do not spread the harm.
6 - Bromo - 2,3 - Difluorobenzenemethanol safety and operating standards, related to personnel safety and experimentation, production of smooth, must not be negligent.
Application Area
6-Bromo-2,3-difluorobenzyl alcohol is also a new product of chemistry. It is widely used in the field of medicine and can be used as the original of special drugs. Because of its special structure, it can separate and combine with various targets, adjust the physiological process, and treat various diseases.
In the field of agrochemical, it can be used as an agent for improving agriculture. Help protect crops, drive away diseases and pests, ensure abundant harvests, increase quality and yield. In the face of material science, or as an important agent for making special materials, add new materials, such as high conductivity, toughness, etc., and expand the scope of use.
Although this product is new, it has great potential in the fields of medicine, agrochemistry, and material science. In the future, it will be important for chemical researchers to develop its capabilities and benefit the world.
Research & Development
In recent years, I have focused on the research of 6 - Bromo - 2,3 - Difluorobenzenemethanol. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path. After many attempts, the ratio of raw materials, reaction temperature and duration were carefully studied. However, the process is difficult, and it is often difficult to encounter the dilemma of poor yield and difficult to remove impurities.
Fortunately, due to unremitting research, the synthesis process has been improved to precisely regulate the reaction conditions, and finally the yield has been steadily increased. At the same time, the relationship between its structure and properties has been deeply analyzed, paving the way for expanding its application.
Looking to the future, we hope that this achievement will be more widely used, shining brightly in the fields of medicine, materials, etc., promoting the development of the industry, and contributing to the progress of scientific research.
Toxicity Research
Toxicity of 6 - Bromo - 2,3 - Difluorobenzenemethanol. The molecular structure of this substance is unique, and the presence of bromine and fluorine atoms may affect its chemical activity and biological effects.
According to various experimental views, in the context of cell culture, appropriate amounts of this substance can cause cell morphological changes and hinder proliferation. Or interfere with key biochemical pathways in cells, such as signal transduction and metabolic circulation.
In animal experiments, after ingestion of the tested animals, the function of the organs was abnormal. Liver metabolism was disordered, and kidney filtration function was also affected. This all shows that 6 - Bromo - 2,3 - Difluorobenzenemethanol has certain toxicity. In the future, its toxicological mechanism should be investigated in detail to provide solid evidence for protection and application restrictions.
Future Prospects
In the field of chemistry, I recently obtained a product named 6 - Bromo - 2,3 - Difluorobenzenemethanol. This product is also exquisite in structure and contains potential.
Looking at the future, it may emerge in the way of pharmaceutical creation. With its unique structure, it may become the basis for targeted drugs and accurately break the disease. And in the way of material innovation, it is also possible. With its characteristics, it may help the birth of new materials, shining in the genus of electronics and optics.
I am convinced that with time and unremitting research, 6 - Bromo - 2, 3 - Difluorobenzenemethanol will be able to show extraordinary posture in various fields and add bright light to the future development.
Where to Buy 6-Bromo-2,3-Difluorobenzenemethanol in China?
As a trusted 6-Bromo-2,3-Difluorobenzenemethanol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 6-Bromo-2,3-Difluorobenzenemethanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

6-Bromo-2, what are the chemical properties of 3-Difluorobenzenemethanol
6 - Bromo - 2,3 - Difluorobenzenemethanol, this is an organic compound. Its chemical properties are unique and valuable for investigation.
First of all, its physical properties, under room temperature, or in a solid state, are caused by its intermolecular forces. Looking at its structure, above the benzene ring, there are bromine atoms, difluorine atoms and hydroxymethyl methyl atoms. Bromine atoms have strong electronegativity, which can cause molecular polarity to change. This property makes the compound soluble in organic solvents or has some solubility, but poor solubility in water, due to the difference between the polarity of water molecules and the polarity of the compound.
Again on its chemical activity, hydroxymethyl groups are active groups and can participate in many chemical reactions. In case of strong oxidizing agent, hydroxymethyl may be oxidized, and then converted into aldehyde group or even carboxyl group. The halogen atom on the benzene ring can also initiate nucleophilic substitution reaction. Under appropriate conditions, bromine atoms may be replaced by other nucleophilic reagents to form new organic compounds. This process requires specific catalysts and reaction environments, such as alkaline media or specific metal catalysts, to make the reaction proceed smoothly.
And because of its fluorine atom, it endows the compound with certain special properties. Fluorine atoms are extremely electronegative, which can enhance molecular stability and affect the interaction between molecules and other substances. This compound may have potential applications in medicine, materials and other fields. In the field of medicine, its unique chemical structure may interact with specific biological targets, exhibit biological activity, and provide opportunities for new drug research and development. In the field of materials, its stability and special physicochemical properties may be used to prepare high-performance materials.
6 - Bromo - 2,3 - Difluorobenzenemethanol with its unique structure, derived from a variety of chemical properties, has potential uses in many fields, and is an important object of chemical research.
What are the main uses of 6-Bromo-2, 3-Difluorobenzenemethanol
6-Bromo-2,3-difluorobenzyl alcohol has a wide range of uses in the field of organic synthesis.
First, it can be used to prepare medicine. In the creation of medicine, these organic compounds are often relied on as starting materials and converted into molecules with specific pharmacological activities through various reactions. The bromine, fluorine and alcohol groups of this compound can be used as reaction check points or introduced into other functional groups to become drugs for treating specific diseases.
Second, in the synthesis of pesticides, it also plays a key role. The research and development of pesticides today requires the precise design of compound structures to achieve high-efficiency insecticidal, herbicidal or bactericidal effects. The unique structure of 6-bromo-2,3-difluorobenzyl alcohol, or compounds that can be derived from it, is highly targeted and active to specific pests or weeds, and the impact on the environment is controllable.
Furthermore, in the field of materials science, this compound may be an important intermediate for the synthesis of special materials. After specific polymerization reactions or modifications, materials can be imparted with excellent optical, electrical or thermal properties. Such as synthesizing materials with specific fluorescence properties for optical sensors; or preparing polymer materials with special stability for extreme environments.
In addition, in the field of chemical research, it can be used as a model compound to assist chemists in exploring reaction mechanisms and investigating fundamental chemical problems such as substituent effects. By studying the reaction of this substrate, we can gain in-depth insight into the essence of organic reactions, and provide theoretical support and methodological guidance for the synthesis of more complex compounds.
What are the synthesis methods of 6-Bromo-2, 3-Difluorobenzenemethanol
The synthesis of 6-bromo-2,3-difluorobenzyl alcohol is an important topic in the field of organic synthesis. One of the common synthesis paths is to use 6-bromo-2,3-difluorobenzoic acid as the starting material. The acid is first reacted with a suitable reducing agent, such as lithium aluminum hydride (LiAlH), in an organic solvent (such as anhydrous tetrahydrofuran) at low temperature and in an anhydrous environment. Lithium aluminum hydride has strong reductive properties and can reduce carboxyl groups (-COOH) to hydroxymethyl (-CH _ 2O OH) to obtain the target product 6-bromo-2,3-difluorobenzyl alcohol. However, this process needs to be operated with caution, because lithium aluminum hydride reacts violently with water and is potentially dangerous.
The second method can be started from 6-bromo-2,3-difluorobrobenzyl. 6-Bromo-2,3-difluorobenzyl bromide is reacted with nucleophilic reagents such as sodium acetate (CH < unk > COONa) in an appropriate solvent (such as N, N < unk > -dimethylformamide, DMF) to generate 6-bromo-2,3-difluorobenzyl acetate, which is then hydrolyzed by alkaline, such as sodium hydroxide (NaOH) aqueous solution, the ester group is hydrolyzed to hydroxymethyl to achieve the synthesis of 6-bromo-2,3-difluorobenzyl alcohol. Although there are a few steps in this path, the raw materials are relatively easy to obtain, and the reaction conditions of each step are relatively easy to control.
Another method is to use 2,3-difluorobenzaldehyde as the starting material. First, 2,3-difluorobenzaldehyde is brominated with a brominating agent, such as N-bromosuccinimide (NBS), in the presence of light or initiator, in a suitable solvent (such as carbon tetrachloride), bromine atoms are introduced at the 6th position of the benzene ring to obtain 6-bromo-2,3-difluorobenzaldehyde, and then the aldehyde group is reduced to hydroxymethyl in an alcohol solvent (such as methanol) with sodium borohydride (NaBH) isothermal and reducing agent, and the final product is obtained. The reaction selectivity of each step is high, the product is pure, and the reduction reaction conditions of sodium borohydride are mild, and the operation is relatively simple.
What is the market price of 6-Bromo-2,3-Difluorobenzenemethanol?
The market price of 6-bromo-2,3-difluorobenzyl alcohol is difficult to determine. The market is volatile, and its price often changes due to various reasons.
First, the situation of supply and demand is due to factors. If there are many people in the market who want this product, but the quantity of production is small, the price will rise; conversely, if the supply exceeds the demand, the price will drop.
Second, the manufacturing cost also affects the price. The price of raw materials, production skills, energy consumption costs, etc., are all related to the cost. The high price of raw materials, or the complicated process causes the energy consumption to increase greatly, and the cost rises, and the price also follows.
Third, the state of market competition has an impact. There are many competitors in the same industry, in order to compete for market share, or there may be price reductions; if this product is unique and the competition is slightly slower, the price may rise steadily.
Fourth, the external environment cannot be ignored. Policy guidance, trade regulations, natural and man-made disasters, etc., can disturb its price. If policies support production, or tariffs change, prices are affected.
According to past changes in chemical prices, the price of 6-bromo-2,3-difluorobenzyl alcohol is between hundreds and thousands of yuan per kilogram or. However, this is only a rough estimate. To know the real-time and accurate price, you need to consult the chemical product trading market, relevant distributors or manufacturers in detail to obtain the exact number.
6-Bromo-2, 3-Difluorobenzenemethanol What are the precautions during storage and transportation?
6-Bromo-2,3-difluorobenzyl alcohol is an important raw material in organic synthesis. During storage and transportation, there are many key matters that need to be paid attention to.
Bear the brunt, and the storage environment is of paramount importance. This compound should be stored in a cool, dry and well-ventilated place. Because the substance is sensitive to heat, high temperature can easily cause it to decompose or deteriorate. If the storage temperature is too high, the internal structure of the molecule may be damaged, which may affect its chemical properties and quality. For example, if it is placed in a warehouse under high temperature in summer, it may change color or produce odor in a short period of time, eventually making it impossible to use it in the established synthesis reaction.
Furthermore, it is necessary to ensure that the storage environment is dry. Due to its certain hygroscopicity, humid environments will cause it to absorb moisture and cause side reactions such as hydrolysis. Once hydrolysis occurs, not only the raw materials themselves are damaged, but the resulting impurities will also interfere with subsequent synthesis. For example, in the rainy season in the south, if the compound is not stored properly, it is very likely to deteriorate due to moisture absorption.
When transporting, the packaging must be solid and well sealed. Suitable packaging materials must be used to prevent damage to the container due to collision and vibration during transportation. If the packaging is not tight enough, once the substance leaks, it will not only cause material loss, but also pose a hazard to transporters and the surrounding environment. For example, if it leaks into the carriage, its smell may irritate the transporter, and it is also difficult to clean up the residual material.
In addition, temperature and humidity must be strictly controlled during transportation. It should be avoided to transport in extreme weather conditions, such as hot summer days or heavy rain. It should also be transported separately from other substances that may react with it to prevent dangerous interactions.
In a word, when storing and transporting 6-bromo-2,3-difluorobenzyl alcohol, high attention should be paid to temperature, humidity, packaging and isolation from other substances to ensure its quality and safety.