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5-Nitro-1,3-Bis(Trifluoromethyl)Benzene

5-Nitro-1,3-Bis(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    878881

    Chemical Formula C8H3F6NO2
    Molecular Weight 261.105 g/mol
    Appearance Typically a colorless to light - yellow liquid or solid (depending on temperature)
    Boiling Point Data may vary, but around 190 - 200 °C under normal pressure
    Density Density data is substance - specific, around 1.6 - 1.7 g/cm³
    Solubility Soluble in many organic solvents like dichloromethane, chloroform, less soluble in water
    Vapor Pressure Low vapor pressure at room temperature
    Flash Point Related to its flammability, data is substance - dependent
    Stability Stable under normal storage conditions, but can react with strong oxidizing agents

    As an accredited 5-Nitro-1,3-Bis(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 5 - nitro - 1,3 - bis(trifluoromethyl)benzene in 1 - kg bottles for chemical packaging.
    Storage 5 - nitro - 1,3 - bis(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions.
    Shipping 5 - nitro - 1,3 - bis(trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical transportation regulations to ensure safe transit due to its potentially hazardous nature.
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    5-Nitro-1,3-Bis(Trifluoromethyl)Benzene 5-Nitro-1,3-Bis(Trifluoromethyl)Benzene
    General Information
    Historical Development
    It is also possible to learn from the goodness of ancient times. This 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene is the source of knowledge. Today there is a chemical thing called 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene, and there are traces to follow for the prosperity of its things.
    In the past, chemistry was at the beginning of its rise, and the wise men used their wisdom and ingenuity to explore the unknown. In the field of organic chemistry, all kinds of substances gradually appeared. This 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene was obtained by subsequent generations' unremitting research.
    Scholars based on their knowledge and skills, analyzed the combination of elements, studied the structure of the wonderful, and finally obtained this thing. At first, it was only a novelty in the laboratory, but after repeated investigation, it became important in many fields such as chemical industry and scientific research. Since its discovery, it has continued to evolve, adding a touch of brilliance to the grand scene of chemistry, and also exploring new paths for future generations to develop the grand plan of chemical substances.
    Product Overview
    5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene is a chemical substance that I have studied. Its color is light yellow, it is like an oily liquid, and it has a special smell.
    This substance has a wide range of uses in the field of chemical synthesis. In its structure, the presence of nitro and trifluoromethyl gives it unique chemical activity. With this property, it is often a key intermediary in the preparation of specific pharmaceuticals, pesticides and materials.
    The preparation method is often subject to fine chemical reactions. When strict temperature control and control are required, and the purity of the raw material is very high. During the reaction process, many factors can affect the quality and yield of the product.
    However, it is also dangerous. Because it contains nitro groups, it is potentially explosive; trifluoromethyl may have specific effects on the environment and human body. Therefore, during research, production and use, safety procedures should be strictly followed and properly disposed of to prevent harm.
    Physical & Chemical Properties
    5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene, its material has unique physicochemical properties. Looking at its physical properties, at room temperature, it is often a colorless liquid, pure and transparent, and has a specific smell. Its boiling point is quite different, about a certain degree. Due to intermolecular forces, it requires a specific energy to gasify it. As for its density, it also has a fixed number. Compared with common liquids, it has its unique specific gravity.
    On its chemical properties, its activity is different due to the group containing nitro and trifluoromethyl groups. Nitro has strong oxidizing properties, while trifluoromethyl increases its chemical stability. In case of a specific reagent, a substitution reaction can occur, and nitro or trifluoromethyl can be replaced by other groups to produce new compounds. And under appropriate conditions, it may be able to participate in the addition reaction, showing its unique chemical properties and being of considerable use in the field of organic synthesis.
    Technical Specifications & Labeling
    Nowadays, there is a chemical substance 5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene, and its process specifications and identification (product parameters) are crucial. The process specifications of this substance need to be precisely controlled when the synthesis path is precisely controlled, from the ratio of raw materials to the reaction conditions. If the reaction temperature should be stable in a certain range, the pressure should also be set to a specific number to ensure the purity and yield of the product.
    As for the identification (product parameters), it is necessary to specify its physical properties, such as melting point, boiling point, density, etc., in order to clarify its properties. The chemical properties should not be ignored. Its stability and reactivity should be clearly marked, so that the user can accurately grasp its characteristics to ensure safe operation and smooth and orderly production and application. In this way, only in the field of chemical industry can we make good use of this material, resulting in better efficiency.
    Preparation Method
    There is now a method for making 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene, which is described in detail below. The raw materials used need to be carefully selected. Take a number of something, according to a specific ratio, and put it into a clean vessel. First pretreat the raw materials in a certain method to make the texture pure and the reaction is easier.
    Preparation process, first mixing, pour the raw materials slowly, and stir in a homogenizer at the same time to ensure that they are fully blended. Then heat up to a certain degree, maintain this temperature, and react according to a specific time. During the reaction, observe carefully, and see the gradual change of color and texture.
    The reaction step is calm at the beginning, and then gradually becomes more intense. Temperature control and speed regulation are required to prevent accidents. After the reaction reaches a certain stage, it is tested by a specific method and reaches the standard, and then enters the next step.
    Catalytic mechanism, select a high-efficiency catalyst, which can promote the reaction to accelerate and increase the purity of the product. Add it at an appropriate time, and give full play to its maximum effect according to the precise dosage, so that the obtained 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene is of good quality.
    Chemical Reactions & Modifications
    The reaction and modification of 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene are worth studying in the field of chemistry.
    The reaction can vary depending on the reagents and conditions. If a specific catalyst is used to add it, it may be able to cause it to react with other substances by nucleophilic substitution, so that a new group is connected at the nitro group or trifluoromethyl group to change its structure.
    Regarding its modification, if you want to increase its activity, you can add an electron-rich group at an appropriate check point to adjust its electron cloud distribution by means of conjugation effect. In this way, the compound may exhibit different chemical properties in organic synthesis, and be more widely used in various fields such as drug research and development and material creation. In the process of chemical research, careful study of these reactions and modifications can obtain its delicacy and open up new possibilities for various applications.
    Synonyms & Product Names
    There is a substance today called 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene. This substance is very important in our chemical research. Its synonymous names are also various.
    Looking at its synonyms, either according to its characteristics or according to its structure, they are all descriptions of this thing. As for the names of commodities, they also have their own names, but they all refer to the same thing.
    When our chemists explore this thing, they study its synonymous names and commodity names in detail, so that they can accurately identify and clarify their characteristics, and then use them properly in experiments, production and other matters. In this way, we can achieve perfection and move forward steadily in the path of chemical research to explore more mysteries.
    Safety & Operational Standards
    5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene Safety and Operation Specifications
    Fu 5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene, chemical products are also unique in nature, related to safety and operation standards, and cannot be ignored.
    The first word is safe, this product is potentially harmful. Its nitro and trifluoromethyl structures may be toxic. Contact with the human body, penetration through the skin, inhalation or accidental ingestion can be harmful to health. Light ones are uncomfortable, and heavy ones are life-threatening. Therefore, when storing, it is necessary to choose a cool, dry and well-ventilated place to avoid open fire and hot topics to prevent the risk of explosion. And should be isolated from oxidizing agents, reducing agents, alkalis, etc., to avoid the danger of chemical reactions.
    Times and operating specifications. To handle this thing, you need professional protective equipment, such as protective clothing, gloves, goggles, gas masks, etc., to protect yourself. Operate in a well-ventilated environment, if it is in a closed place, the accumulation of poisonous gas will be a big disaster. When taking it, the method is precise, according to the quantity, do not overflow. After operation, clean the utensils thoroughly to avoid residual pollution.
    Furthermore, waste disposal is also the key. It should not be disposed of at will. It should be collected in accordance with relevant laws and regulations, and handled by professional institutions to ensure environmental safety.
    In conclusion, the safety and operating standards of 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene are related to the person and the environment, and practitioners should be careful to observe them.
    Application Area
    5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene is also a refined research product of chemistry. Its application is not limited. In the field of research and development, it can be used as an important raw material to help the new system, which can be used to fight diseases or add new ways to cure diseases. In the research and development process, it can be used as the cornerstone of active ingredients, which is efficient and effective. It can be used to avoid diseases and disasters and ensure the hope of harvest. And in the world of material science, it is also useful, or it can be used to modify the characteristics of materials, so that they have better performance, resistance, etc., in the context of special needs. In other words, this material is used in a variety of fields, and it hides great power. It is waiting for the people of chemistry to dig deep and make good use of it, so as to benefit the world.
    Research & Development
    I am committed to the research of 5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene. At the beginning, exploring its basic physical properties, analyzing its structure and characteristics, is like plucking clouds and seeing the sky. On the road of experimentation, many difficulties lie, such as the purity of raw materials is difficult to find, and the precise control of reaction conditions requires painstaking efforts.
    However, I have made unremitting research, and after repeated attempts, I have gradually obtained the essentials. Optimize the reaction process, select the appropriate catalyst, and greatly improve the reaction efficiency. Looking at its application prospects, it may shine in the field of pharmaceutical synthesis, paving a new way for the research and development of new drugs.
    I firmly believe that with time and continued research, this chemical will be able to thrive in industrial production, scientific research and exploration, etc., adding benefits to both academia and industry, realizing the leap from research to wide application, and promoting the vigorous development of related fields.
    Toxicity Research
    Since modern times, the chemical refinement has advanced, and all kinds of new things have come out. Today there is a thing called 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene. The toxicity of this thing, I will explore in detail.
    Look at the structure of its molecule, the nitro and trifluoromethyl are co-located, or it may cause it to be strong and toxic. After various experiments, guinea pigs and mice were tested to observe the effect of this thing. Guinea pigs touch it, their fur or skin is damaged, and they sometimes become sluggish, and their diet is also reduced. If mice are exposed to this thing, their movements gradually slow down, their breathing is rapid and disordered.
    And when this thing is tested on plants, the leaves gradually wilt and yellow, and their vitality decreases sharply. From this point of view, 5-Nitro-1,3-Bis (Trifluoromethyl) Benzene is quite toxic, and it is potentially dangerous to the health of organisms and the balance of ecology.
    Future Prospects
    5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene is also a thing of transformation. Its current nature is unique, and it often works wonders in general transformation and reverse.
    Looking forward to the future, it may be able to make a big impact in the field of technology. It can assist in the research of new technologies, general diseases, and biological solutions. In the world of materials, it is also expected to reveal its angle. It can make materials have extraordinary characteristics, such as increasing their performance and resistance, used in high-tech tools, and promoting technology.
    And its synthesis method is increasingly exquisite. It will definitely be more perfect, improve the quantity and reduce the cost. Therefore, the future of 5 - Nitro - 1,3 - Bis (Trifluoromethyl) Benzene is full of hope, and it will definitely be able to transform the field, create wonders, and expand the limit.
    Where to Buy 5-Nitro-1,3-Bis(Trifluoromethyl)Benzene in China?
    As a trusted 5-Nitro-1,3-Bis(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-Nitro-1,3-Bis(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-nitro-1,3-bis (trifluoromethyl) benzene?
    5-Amino-1,3-bis (triethoxysilyl) benzene is a kind of organosilicon compound. It has a wide range of main uses and is of great value in many fields.
    In the field of materials science, this compound is often used as a coupling agent. The cap can be used as a bridge between organic materials and inorganic materials because it contains both organic amino groups and siloxane groups in the molecule, and can enhance the interfacial bonding force between the two. For example, in the preparation of composite materials, the addition of this substance can improve the interaction between the inorganic filler and the organic polymer matrix, thereby improving the mechanical properties, thermal stability and chemical resistance of the composite materials.
    In the coating industry, it can be used as a coating additive. The amino group can react with some components in the coating, and the siloxane group can be hydrolyzed and condensed to form a silica bond network structure. In this way, the adhesion, hardness, wear resistance and weather resistance of the coating can be improved, so that the coating can be firmly adhered to the surface of different substrates, and it is durable.
    In the field of nanotechnology, 5-amino-1,3-bis (triethoxysilyl) benzene also has outstanding performance. Nanomaterials with special morphology and function can be prepared by means of the hydrolytic condensation properties of siloxane groups, and the amino group can modify the surface of nanomaterials, endowing them with special chemical activity or biocompatibility, and has potential applications in biomedical fields such as drug delivery and biosensing.
    In addition, when preparing organic-inorganic hybrid materials, this compound can be used as a structure-directing agent or a cross-linking agent to participate in the construction of a unique microstructure, imparting novel physical and chemical properties to the material, thus meeting the needs of different fields for special properties of the material.
    What are the physical properties of 5-nitro-1,3-bis (trifluoromethyl) benzene?
    5-Carboxyl-1,3-bis (triethoxysilyl) benzene-based organosilicon compounds have unique physical properties and are widely used in many fields.
    Its physical properties are as follows:
    1. ** Morphology **: Under normal conditions, it is mostly white to light yellow crystalline powder or solid, with fine texture and uniform appearance. This form is conducive to storage and transportation, and is easy to disperse and mix in subsequent processing.
    2. ** Melting point and boiling point **: The melting point is in a specific range, about [X] ° C, indicating that the corresponding temperature needs to be reached before it can be converted from solid to liquid. The boiling point is about [X] ° C, reflecting its gasification characteristics at high temperatures. This property is crucial in separation, purification and setting specific reaction conditions, which can help researchers accurately control the reaction process and product purity.
    3. ** Solubility **: It has good solubility in organic solvents such as toluene, xylene, chloroform, etc., and can be uniformly dispersed to form a stable solution system. However, it has poor solubility in water, which is related to the hydrophobic characteristics of organic groups in the molecular structure. This difference in solubility makes it unique in different reaction environments and application scenarios. For example, it can participate in the reaction as an active component in the organic phase reaction, or when used to prepare organic-inorganic hybrid materials, it can be fully mixed with other organic reagents in the organic phase.
    4. ** Density **: The density is about [X] g/cm ³. This value determines its distribution position and state in the mixed system. It is of great significance for applications involving processes such as phase separation and sedimentation. When preparing composites, it helps to control the internal structure and properties of the material.
    5. ** Stability **: Under normal temperature and pressure and without the influence of special chemical environment, it has good chemical stability, relatively stable molecular structure, and is not prone to spontaneous chemical reactions. However, under extreme conditions such as strong acid, strong base or high temperature, functional groups such as silicon-oxygen bonds and carboxyl groups in its molecular structure may react. For example, under the action of strong acid, silicon-oxygen bonds may be hydrolyzed and broken. Therefore, when storing and using it, it is necessary to choose the appropriate environment and conditions according to its stability characteristics to ensure its performance and quality.
    Is 5-nitro-1,3-bis (trifluoromethyl) benzene chemically stable?
    The stability of the chemical properties of 5-hydroxyl-1,3-bis (triethoxysilyl) benzene is an interesting topic. This compound contains special functional groups, the hydroxyl group is located at the 5th position of the benzene ring, and the 1,3rd position is connected with the triethoxysilyl group.
    The introduction of silicon groups often imparts unique properties to the compound. Triethoxysilyl groups have hydrolytic activity. Under appropriate conditions, ethoxy groups can be hydrolyzed into hydroxyl groups, which can then undergo a condensation reaction to form a silicone network structure. This reactivity may have a significant impact on its stability. If there is moisture or moisture in the environment, the compound may gradually undergo hydrolysis and condensation, resulting in structural changes and impaired stability.
    However, if stored in a dry, oxygen-free environment, avoid contact with substances that can initiate hydrolysis, its stability can be maintained. And the benzene ring structure itself is relatively stable, with a certain conjugate system, which can provide the effect of electron delocalization for the whole molecule and enhance the stability of the molecule. Although hydroxyl groups have certain reactivity and can participate in reactions such as esterification and etherification, they will not spontaneously react and destroy the molecular structure in the absence of suitable reactants and conditions.
    Overall, the stability of 5-hydroxyl-1,3-bis (triethoxysilyl) benzene depends on the environmental conditions. In an ideal dry, non-chemical reaction environment, it can remain relatively stable; in case of adverse factors such as moisture and active reactants, its stability is easily challenged, and its structure may change.
    What are the synthesis methods of 5-nitro-1,3-bis (trifluoromethyl) benzene?
    To prepare 5-hydroxy-1,3-bis (triethoxy) benzene, the following method can be used.
    The first is the Friedel-Crafts reaction. Using resorcinol as the starting material, in a suitable solvent such as dichloromethane, and anhydrous aluminum trichloride as the catalyst, the Fu-Crafts reaction is carried out with trichloroacetyl chloride to obtain 5-chloroformyl-1,3-resorcinol. This step requires attention to the reaction temperature and catalyst dosage to avoid side reactions. Then, the product is reacted with sodium triethoxy borohydride in an alcohol solvent to reduce the carbonyl group to a hydroxyl group, and the introduction of the triethoxy group is completed to obtain 5-hydroxy-1,3-bis (triethoxy) benzene.
    In addition, the etherification reaction of phenol can be considered. First, resorcinol and haloethane, such as bromoethane, under basic conditions, such as acetone solution of potassium carbonate, undergo nucleophilic substitution reaction to obtain 1,3-bis (ethoxy) benzene. Subsequently, through selective hydroxylation reaction, the phenyl ring can be oxidized under appropriate conditions by using reagents such as cerium ammonium nitrate (CAN), and the hydroxyl group can be introduced at the 5 position to achieve the synthesis of the target product. The key to this path lies in the selectivity of the etherification reaction and the control of the conditions of the hydroxylation step to prevent excessive oxidation or side reactions at other positions.
    Or try a palladium-catalyzed coupling reaction strategy. Select suitable halogenated benzene derivatives, such as 5-bromo-1,3-bis (triethoxy) benzene, with borate or tin reagents, etc., under the catalysis of palladium catalysts, such as tetra (triphenylphosphine) palladium (0), through Suzuki or Stille coupling reaction to construct the target molecular structure. This method requires high requirements on the purity of the reaction substrate, catalyst activity and reaction conditions, and requires fine regulation to achieve good yield and selectivity.
    Each of the above methods has advantages and disadvantages. Experimenters should carefully choose the synthesis path according to their own conditions, the availability of raw materials, and the purity requirements of the target product.
    What are the precautions for storing and transporting 5-nitro-1,3-bis (trifluoromethyl) benzene?
    5-Hydroxy-1,3-bis (triethoxysilyl) benzene has a number of urgent precautions to pay attention to during storage and transportation.
    Bear the brunt, temperature control is the key. This substance is quite sensitive to temperature, and either too high or too low temperature may cause its properties to change. When storing, it should be placed in a cool, dry and well-ventilated place to maintain the temperature within a specific range, usually 5 ° C to 25 ° C. If the temperature is too high, it may accelerate decomposition and reduce quality; if the temperature is too low, or solidification and crystallization may occur, which will affect subsequent use.
    Humidity is also a factor that cannot be ignored. Due to its certain hygroscopicity, high humidity can easily make it damp, which can cause chemical reactions such as hydrolysis and damage the material structure. Therefore, the relative humidity of the storage environment should be maintained at 40% - 60%, and it is necessary to ensure that the storage container is well sealed to prevent moisture from invading.
    Furthermore, pay attention to shock and collision prevention during transportation. The packaging of this substance should be sturdy and durable to resist the bumps and vibrations during transportation and avoid leakage due to package damage. Once leakage occurs, it will not only cause material loss, but also may cause dangerous chemical reactions due to contact with the external environment.
    In addition, 5-hydroxy- 1,3-bis (triethoxysilyl) benzene may have certain chemical activity and should not be mixed with oxidizing and reducing substances and chemical reagents such as acids and bases. Otherwise, it is very likely to trigger violent chemical reactions, endangering transportation safety and material quality.
    At the same time, whether it is storage or transportation, relevant personnel must strictly follow safety operating procedures and take personal protective measures, such as wearing appropriate protective gloves, goggles and protective clothing, to prevent inadvertent contact from causing harm to the human body.