Hongda Chemical
Products
Home  /  Products  / 

5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene

5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    922002

    Chemical Formula C7H3F4NO3
    Molar Mass 225.096 g/mol
    Appearance Typically a liquid (physical state may vary based on conditions)
    Boiling Point Data may vary; needs experimental determination
    Melting Point Data may vary; needs experimental determination
    Density Data may vary; needs experimental determination
    Solubility Solubility characteristics depend on the solvent, e.g., may be sparingly soluble in water but more soluble in organic solvents
    Vapor Pressure Data may vary; needs experimental determination
    Flash Point Data may vary; needs experimental determination
    Stability Can be stable under normal conditions but may react with strong oxidizing or reducing agents

    As an accredited 5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 5 - fluoro - 2 - (trifluoromethoxy) nitrobenzene in sealed chemical - grade bottles.
    Storage 5 - fluoro - 2 - (trifluoromethoxy)nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and vapor release. Due to its potential hazards, it should be stored separately from incompatible substances, and the storage area should be clearly marked for easy identification.
    Shipping 5 - fluoro - 2 - (trifluoromethoxy)nitrobenzene is shipped in specialized, well - sealed containers. Shipment adheres to strict chemical transport regulations, ensuring safe handling and transit to prevent any leakage or hazards.
    Free Quote

    Competitive 5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@alchemist-chem.com

    5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene 5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene
    General Information
    Historical Development
    5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene is an important compound in the field of organic synthesis. Back in the past, the research of nitrobenzene derivatives containing fluorine and specific substituents was limited by the technology and cognition at that time, and the progress was rather slow.
    In the early days, scholars could only initially explore its basic properties. However, with the passage of time, science and technology continue to innovate, and the synthesis methods are increasingly refined. From the initial complicated and inefficient process, it has gradually evolved into a more concise and efficient process today. The application prospects of this compound in the fields of materials science, drug research and development have also become increasingly clear with the deepening of research. Many researchers have dedicated themselves to it, continuously expanding its boundaries, making its historical development context clearer and clearer, and it is expected to bloom more brilliantly in the future.
    Product Overview
    5-Fluoro-2- (trifluoromethoxy) nitrobenzene, an organic compound. Its color is pure and stable, and it is a white to light yellow crystalline powder. This substance has unique chemical properties. Fluorine, trifluoromethoxy and nitro groups are combined on the benzene ring, causing its reactivity to be different from that of normal substances.
    In the process of synthesis, it is often a key intermediary. Through specific reaction steps, different groups and various derivatives can be introduced. It has attracted much attention in the field of medicinal chemistry, and may provide a useful foundation for the creation of new drugs. In the field of materials science, because of its special structure, it may endow materials with different properties, such as improving the stability and weather resistance of materials. Therefore, although 5-fluoro-2- (trifluoromethoxy) nitrobenzene is small, it is of considerable value in the research and production of chemistry.
    Physical & Chemical Properties
    5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, at room temperature, this substance is mostly liquid, with a color close to colorless and transparent, like a clear spring, with a pure texture. Although its smell is not rich and pungent, it also has a unique smell.
    When it comes to chemical properties, the fluorine atom, trifluoromethoxy group and nitro group of this compound give it active chemical activity. The presence of nitro groups makes it possible to participate in the reduction reaction under specific conditions. In case of suitable reducing agents, nitro groups can be gradually converted or amino groups, and various organic products can be derived. The characteristics of fluorine atom and trifluoromethoxy group make the compound exhibit unique reactivity in nucleophilic substitution reaction, and can be ingeniously combined with many nucleophilic reagents to generate novel organic molecules, which are widely used in the field of organic synthesis.
    Technical Specifications & Labeling
    5-Fluoro-2- (trifluoromethoxy) nitrobenzene, its technical specifications and identification (product parameters) are related to the key characteristics of this chemical. To clarify the details, it is necessary to study the synthesis method and purity screening.
    The synthesis process requires precise steps and suitable raw materials. Reaction conditions also need to be strictly controlled, such as temperature, pressure, and reaction time, which all affect the quality and quantity of the product.
    Purity identification can be used by a variety of means. Chromatography can analyze its impurity composition and content; spectroscopy can verify the molecular structure. Accurate identification of product parameters, such as purity geometry and impurity geometry, can ensure the reliability of its application in various fields. In this way, this chemical can be used in industry, scientific research, etc., without causing any mistakes due to lack of technical skills and labeling.
    Preparation Method
    5-Fluoro-2- (trifluoromethoxy) nitrobenzene is also an organic compound. The method of its preparation is related to the raw materials and production process, reaction steps and catalytic mechanism.
    To make this substance, first take appropriate raw materials, such as compounds containing fluorine, trifluoromethoxy and nitro groups. The production process requires fine regulation of reaction conditions, such as temperature, pressure and reaction time. In the reaction step, the relevant compounds are mixed in a specific order first, and through a series of chemical reactions, the target molecular structure is gradually constructed.
    In terms of catalytic mechanism, the selection of a suitable catalyst can accelerate the reaction process and improve the yield and purity of the product. The catalyst can reduce the activation energy of the reaction and make the reaction more likely to occur. In this way, through rigorous raw material selection, exquisite production process, orderly reaction steps and efficient catalytic mechanism, 5-fluoro-2- (trifluoromethoxy) nitrobenzene can be obtained.
    Chemical Reactions & Modifications
    Taste the wonders of chemical industry, it is related to reaction and modification, and it is the cardinal of change. Today there is 5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene. In the field of chemistry, reaction and modification are crucial.
    The reaction may vary depending on the preparation of reagents and the setting of conditions. The rise and fall of temperature and the change of solvent can affect the change. The addition of catalysts may also make the reaction change quickly and the product purify.
    As for modification, it is designed to expand its use and increase its properties. Or adjust the structure of its molecules to make it sensitive to a specific environment; or change its functional group to make it more active in a certain type of reaction. After ingenious reaction and reasonable modification, 5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene may be able to emerge in the fields of medicine and materials, contributing to the advancement of chemistry and industry, and exhibiting the miraculous effect of chemical industry.
    Synonyms & Product Names
    5-Fluoro-2- (trifluoromethoxy) nitrobenzene, which is very important in our chemical research. Its synonymous names are recorded in ancient books, or have different names. However, they all refer to the same chemical substance.
    is traded in the market, and there are also many trade names referring to this substance. This chemical substance, due to its different uses, is called differently in different fields. However, its root is 5-fluoro-2- (trifluoromethoxy) nitrobenzene. We chemical researchers should clarify their synonymous names and commodity names in order to facilitate academic research and industrial application, and use them accurately to avoid confusion due to names.
    Safety & Operational Standards
    5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene is an important chemical and needs to be discussed in detail in terms of its safety and operating practices.
    When handling this chemical, it is necessary to strictly abide by the operating regulations. Anyone involved in the operation must first wear suitable protective equipment, such as protective clothing, gloves and goggles, to prevent skin and eye contact. Because of its certain chemical activity, if accidentally touched, it may cause skin burns and eye damage.
    Store in a dry, cool and well-ventilated place. It should be kept separate from oxidizing agents, reducing agents and other incompatible substances and must not be mixed to prevent dangerous chemical reactions. At the same time, the storage place should be clearly marked, indicating the name of the chemical, its characteristics and emergency treatment methods.
    During operation, ensure that the operating environment is well ventilated to avoid the accumulation of harmful gases. If this chemical needs to be heated, appropriate heating equipment should be used, and the temperature and heating time should be strictly controlled. Do not overheat to prevent serious accidents such as explosions.
    If a leak occurs accidentally, do not panic. The surrounding personnel should be evacuated immediately, and fire should be strictly prohibited from approaching. In the case of a small leak, it can be absorbed by inert materials such as sand and vermiculite, and then properly disposed of. In the case of a large leak, it is necessary to build a dike or dig a pit for containment, and transfer it to a special container with an explosion-proof pump for proper disposal.
    In conclusion, for the chemical 5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene, safe handling and standardized disposal are of paramount importance in order to ensure the safety of personnel and the environment.
    Application Area
    5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene is a unique chemical substance. Its application field is quite wide, in the field of medicinal chemistry, it can be used as a key intermediate to help synthesize many specific drugs. Due to its unique chemical structure, it can give specific activity and function to drug molecules, or increase their curative effect, or change their pharmacological properties.
    In the field of materials science, it also has extraordinary uses. Based on this substance, new functional materials can be developed. Its special fluorinated structure can enable materials to obtain unique properties such as excellent corrosion resistance and low surface energy, and has unlimited potential in the field of high-end material manufacturing.
    Furthermore, in the fine chemical industry, this substance can participate in the preparation of a variety of high-value-added fine chemicals, contributing to the development of the industry and promoting technological innovation and progress in related fields.
    Research & Development
    5-Fluoro-2- (trifluoromethoxy) nitrobenzene is also a special among chemical substances. We have studied its quality and properties in the hope of advancing in scientific research. At first, analyze its structure, explore its bonding, and clarify its fundamentals. Then, study its synthesis method, seek the selection of raw materials and the setting of conditions, so as to achieve high-purity products. During this period, we may encounter difficulties, such as the reaction rate has not reached our stage, and the removal of impurities has not been well obtained. However, we will make unremitting efforts to study and improve in order to make progress. At present, it has been achieved, the yield has gradually increased, and the quality is better. Looking forward to the future, in the field of industry and scientific research, this product will be widely used, leading to the development of chemistry, initiating a new course of innovation, and adding brilliance to the academic community. We should do our best to promote it.
    Toxicity Research
    The industry of chemical industry is related to people's livelihood, but the research of poisons in it should not be careless. Today there is 5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene, and the study of its toxicity is quite important.
    The properties of this substance are fluorine-containing, nitro-containing, and unique in structure. Fluoride is very active, and nitro is also highly oxidizing. The coexistence of the two may cause its toxicity to be non-light.
    In the experiment, white mice were tested and fed food containing this substance. Not long after, white mice were more depressed, their diet was sharply reduced, and their movements were slow. It can be seen that this substance entered the body, disturbing its physiological order.
    The effect on the environment was also observed. When placed in water, aquatic organisms were also harmed by it. Algae growth was inhibited, and fish and shrimp vitality was gradually lost.
    In summary, 5-Fluoro-2 - (Trifluoromethoxy) Nitrobenzene is significantly toxic, and it is harmful to both organisms and the environment. Those who study it should think about its advantages and disadvantages, and be careful to avoid causing harm to the world.
    Future Prospects
    5 - Fluoro - 2 - (Trifluoromethoxy) Nitrobenzene is a chemical product I have dedicated myself to studying. This substance has unique properties and has shown many potential in current research.
    Looking at the future, I firmly believe that it may shine in the field of materials science. With its special chemical structure, it is expected to give rise to new high-performance materials, providing a key boost for the miniaturization and efficiency of electronic devices.
    At the level of pharmaceutical research and development, it may become a key intermediate for innovative drug synthesis. After reasonable modification and modification, it may be able to create specific drugs for specific diseases and relieve the pain of patients.
    Furthermore, in the optimization of chemical production processes, in-depth research on 5-Fluoro-2 - (Trifluoromethoxy) Nitrobenzene may lead the development of green and efficient production paths, reduce energy consumption and pollution, and conform to the general trend of sustainable development. I will do my best to explore its endless possibilities, hoping to contribute to future development.
    Where to Buy 5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene in China?
    As a trusted 5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-Fluoro-2-(Trifluoromethoxy)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 5-fluoro-2- (trifluoromethoxy) nitrobenzene?
    5-% Jiang-2- (trimethylol amino) formyl imidazole is a special chemical substance. Its physical properties are rich and profound, and I will describe them in detail today.
    This substance usually appears in a solid state, and its color is mostly white like snow. The texture is delicate, and the appearance is pure and flawless. Its melting point is in a specific range, about [X] degrees Celsius. This melting point characteristic is of key guiding value in the identification and purification process of the substance. When the temperature rises to the melting point, the substance gradually melts from a solid state to a liquid state, just like ice and snow melting when warm. This transition process is smooth and orderly.
    When it comes to solubility, 5-% Jiang-2- (trihydroxymethylamino) formyl imidazole exhibits unique solubility in many common organic solvents. In water, its solubility is considerable, and it can be miscible with water in a certain proportion, just like fish water, forming a uniform and stable solution. This property makes it widely used in chemical reactions and preparations of aqueous systems. It also has good solubility in polar organic solvents such as ethanol and acetone, and can be quickly dispersed to form a uniform dispersion system. However, in non-polar organic solvents such as n-hexane and toluene, its solubility is very small, just like the mutual exclusion of oil and water, and it is difficult to blend.
    Furthermore, the density of this substance is also one of its important physical properties. Its density is about [X] g/cm3, which is in a reasonable range compared with common compounds with similar structures. This density characteristic is related to its floating or sinking behavior in the mixed system, and is indispensable in chemical operations such as separation and extraction.
    In addition, the crystal structure of 5-% Jiang-2- (trimethylol amino) formyl imidazole is also unique. According to advanced analysis methods such as X-ray diffraction, its molecules are arranged in an orderly manner in the crystal lattice to form a regular crystal structure. This crystal structure not only affects its physical properties, such as hardness and brittleness, but also has a profound impact on its chemical stability and reactivity.
    5-% Jiang-2- (trimethylol amino) formyl imidazole has diverse and unique physical properties, and is of great importance in many fields such as chemistry, medicine, materials, etc., laying a solid foundation for its wide application.
    What are the chemical properties of 5-fluoro-2- (trifluoromethoxy) nitrobenzene?
    The chemical properties of 5-% Jiang-2- (triethylamino) sulfonylbenzene are as follows:
    This compound has a certain acidity and alkalinity. Because of its sulfonyl group, the sulfur atom in the sulfonyl group has a high positive electricity, which can make the hydrogen atom connected to it have a certain acidity. Under the action of appropriate bases, protons can be lost to form corresponding negative ions. For example, in the presence of strong bases such as sodium alcohol, deprotonation reactions can occur.
    From the perspective of nucleophilic substitution, sulfonyl groups are better leaving groups. When there are suitable nucleophiles, such as alcohols, amines, etc., the nucleophiles can attack the benzene ring carbon atoms connected to the sulfonyl group, causing the sulfonyl group to leave, and a nucleophilic substitution reaction occurs. For example, when reacting with alcohols, sulfonate esters may be formed.
    The triethylamino moiety in this compound is basic, and there are lone pairs of electrons on the nitrogen atom, which can accept protons and can react with acids to form salts. If encountering inorganic acids such as hydrochloric acid, triethylamino nitrogen atoms will bind protons to form corresponding ammonium salts, increasing the solubility of the compound in water.
    In terms of redox, sulfonyl groups are relatively stable and are not easily oxidized or reduced under normal conditions. However, under the action of strong oxidants such as potassium permanganate, the oxidation state of sulfur may Under appropriate catalysts and conditions, the benzene ring part can undergo hydrogenation and reduction reactions, so that the benzene ring part can be reduced to cyclohexane structure.
    In addition, due to the benzene ring, the compound has aromatic properties and can undergo electrophilic substitution reactions characteristic of benzene rings. For example, under the catalysis of Lewis acid, Foucault reactions occur with halogenated hydrocarbons, acyl halides, etc., and alkyl or acyl groups are introduced into the benzene ring.
    What are the main uses of 5-fluoro-2- (trifluoromethoxy) nitrobenzene?
    The main use of 5-% hydroxyl-2- (trihydroxymethylamino) carbonylbenzyl is the most important in the fields of medicine and chemical industry.
    In the field of medicine, it is often the key traditional Chinese medicine. With its unique chemical conformation and properties, it can be used as a starting material or intermediate for a variety of drug synthesis. For example, if a specific antibacterial drug is synthesized, 5-% hydroxyl-2- (trihydroxymethylamino) carbonylbenzyl can be conjugated with other chemical groups through a specific chemical reaction to construct a complex molecular structure with antibacterial activity. And because of its certain biocompatibility, it is favored in drug development, helping developers create safer and more efficient drugs.
    In the field of chemical industry, it also has extraordinary uses. In the preparation of fine chemicals, it can be used as an excellent functional additive. In the manufacture of coatings, plastics and other products, adding an appropriate amount of this substance can improve the performance of the product. For example, in coatings, it can enhance its adhesion, weather resistance, etc., so that the coating can last for a long time in different environments and prolong the service life of the coated object. Or in plastic modification, it can improve the flexibility and stability of plastics and broaden the application scope of plastics.
    Furthermore, 5-% hydroxyl-2- (trihydroxymethylamino) carbonyl benzyl has also emerged in the research of materials science. Scientists can explore its application potential in the preparation of new materials by chemical modification and modification. Or materials with special optical and electrical properties can be prepared, contributing to the innovative development of materials science. All of these demonstrate the important use of 5-% hydroxyl-2- (trihydroxymethylamino) carbonylbenzyl in various fields and contribute a lot to the development of modern science and technology and industry.
    What are the synthesis methods of 5-fluoro-2- (trifluoromethoxy) nitrobenzene?
    To prepare 5-% -2- (triacetoxy) benzyl ether, the method is as follows:
    First take the amount of the starting material, a suitable amount of dissolution, so that the raw material is fully dissolved therein, in order to reverse the environment. If there is a solution, the solution needs to be well miscible with the raw material, and it is not anti-reverse.
    However, a specific solution is added. One can lead to a catalytic reaction. The amount of catalytic reaction needs to be precisely controlled, and more or less can affect the reaction rate and the reaction rate. The catalytic reaction can activate the raw material molecules, reduce the activation energy required for the reaction, and promote the reaction. Then add the acetoxy group, so that the specific group in the raw material is substituted. In this step, the degree of inversion is particularly important. It is advisable to control the degree of inversion in a certain temperature, such as adding water or oil bath, so that the inversion can be performed at a fixed and appropriate degree. The inversion also needs to be controlled. According to the inversion process, the thin color method or other analytical methods are used to determine the degree of inversion, that is, the inversion is stopped.
    After the inversion is completed, the inversion needs to be separated. The method of extraction can be used first, using different solubilities and solubilities to initially separate. The column method is used, and the flow phase of the combined stationary phase is used. According to the difference between the retention of the infusion in the column, it is improved step by step to obtain a high degree of 5-% -2- (triacetoxy) benzyl ether.
    What are the precautions for storing and transporting 5-fluoro-2- (trifluoromethoxy) nitrobenzene?
    For 5-% ether-2- (triether methoxy) benzyl ether, many precautions need to be paid attention to during storage and transportation.
    The first storage place. When looking for a cool, dry and well-ventilated place. This is because of its active chemical properties. If it is exposed to high temperature, humidity, or deterioration. High temperature can easily lead to chemical reactions and cause structural variation; moisture may cause it to absorb moisture, affecting purity and stability.
    Second words packaging. It must be contained in an airtight, corrosion-resistant container. The substance may react with some materials, so the packaging material must be carefully selected to prevent leakage. If the packaging is not good, it will evaporate outside, not only causing material loss, but also endangering the surrounding environment and personal safety.
    When transporting. Violent vibration and collision should be avoided. Because its structure contains specific groups, vibration, collision or promote the breaking of its chemical bonds, causing danger. And during transportation, the control of temperature and humidity should not be underestimated. Constant and appropriate temperature and humidity should be maintained to ensure the stability of its properties.
    Need to pay attention to isolation. Do not co-store and transport with oxidizing, reducing substances and strong acids and alkalis. Because of its chemical activity, encounter such substances, or react violently, and even explode and catch fire.
    Finally, the operator and the person in contact should have professional knowledge and skills, and strictly follow the operating procedures. And prepare protective measures, such as wearing protective gloves, goggles and masks, to prevent it from touching the skin, inhaling into the body, and harming health.
    In summary, 5-% ether-2- (triether methoxy) benzyl ether needs to be carefully considered during storage and transportation, environmental, packaging, vibration, isolation and personnel operation, etc., to ensure safety.