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5-Fluoro-2-Methylbenzeneacetonitrile

5-Fluoro-2-Methylbenzeneacetonitrile

Hongda Chemical

Specifications

HS Code

785640

Chemical Formula C9H8FN
Molecular Weight 151.164 g/mol

As an accredited 5-Fluoro-2-Methylbenzeneacetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 5 - fluoro - 2 - methylbenzeneacetonitrile: Packed in 1 - kg bottles for safe storage and transport.
Storage 5 - fluoro - 2 - methylbenzeneacetonitrile should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and exposure to air and moisture. Label the storage container clearly to avoid confusion and ensure proper handling.
Shipping 5 - fluoro - 2 - methylbenzeneacetonitrile is shipped in specialized, leak - proof containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, secure packaging, and transport by authorized carriers to prevent any risks during transit.
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5-Fluoro-2-Methylbenzeneacetonitrile 5-Fluoro-2-Methylbenzeneacetonitrile
General Information
Historical Development
5 - Fluoro - 2 - Methylbenzeneacetonitrile, the thing of transformation is also. At the beginning, it is in the field of transformation, studying physical properties, and exploring new paths. At the beginning, I want to get this thing, but I am very troubled, but I am determined.
In the month of December, the, or This is the unremitting work of the predecessors, so that 5 - Fluoro - 2 - Methylbenzeneacetonitrile from the name to the name, and in the history of chemistry, it will remain.
Product Overview
5 - Fluoro - 2 - Methylbenzeneacetonitrile is a chemical product I have recently studied. This product has unique properties, good color purity and quality. It is a white to off-white crystalline powder with good dissolution characteristics in specific solvents. The preparation process is exquisite. After many complicated processes, it is necessary to precisely control the reaction conditions. The temperature, time and proportion of reactants cannot be lost.
This product has extraordinary potential in the field of organic synthesis. It can be used as a key intermediate and participate in the construction of a variety of complex compounds. Its unique chemical structure endows many excellent properties. It may contribute to the creation of new drugs in the field of pharmaceutical research and development, and may also lead to the generation of new materials with excellent performance in the field of materials science. I will continue to explore its potential uses and contribute to the development of the chemical field.
Physical & Chemical Properties
5 - Fluoro - 2 - Methylbenzeneacetonitrile is an organic compound. Its physical properties are mostly liquid at room temperature, with a special odor, and it is insoluble in water, soluble in common organic solvents such as ethanol, ether, etc. Its chemical properties are active, and the cyanyl group can undergo hydrolysis to generate corresponding carboxylic acids; it can also undergo addition reactions with nucleophilic reagents. The presence of fluorine atoms and methyl groups affects the electron cloud density of the benzene ring and changes the activity of electrophilic substitution reactions on the benzene ring. Due to its unique physical and chemical properties, it can be used as a key intermediate in the field of organic synthesis, used in the synthesis of a variety of drugs and functional materials, and plays an important role in chemical research and industrial production.
Technical Specifications & Labeling
5 - Fluoro - 2 - Methylbenzeneacetonitrile is an important intermediate in organic synthesis. Its preparation process needs to strictly follow specific technical specifications and standards.
In terms of technical specifications, the selection of raw materials needs to be pure and meet the corresponding specifications. The control of reaction conditions is extremely critical, and parameters such as temperature, pressure and reaction time need to be precisely controlled. If in a specific reaction stage, the temperature should be maintained at XX ° C. Too high or too low may cause reaction deviation, affecting product purity and yield.
Product labeling is related to product quality and safety and is indispensable. Product labels should clearly label the name, molecular formula, molecular weight and other commodity parameters. Hazardous characteristics, storage conditions and other important information should also be noted to prevent misuse and ensure that the user can operate and store according to the specifications. In this way, the quality and application safety of 5-Fluoro-2-Methylbenzeneacetonitrile can be guaranteed.
Preparation Method
This 5 - Fluoro - 2 - Methylbenzeneacetonitrile has its own method. First take the raw materials, such as fluoride, methyl benzene, etc., according to a certain ratio, according to the specific process.
The first step is the reaction step, in the suitable container, control the temperature and pressure, so that the raw materials can react. This reaction needs to be precisely regulated to ensure that it is sufficient and orderly. If an appropriate catalyst is used to help it, the reaction process will be accelerated and the yield will be improved.
Furthermore, the purification mechanism is used. After the reaction is completed, the product or containing impurities should be purified by a suitable method. It can be distilled to divide the impurities according to the boiling point of each substance; it can also be extracted to select the appropriate extractant to purify the product. After these steps, a relatively pure 5-Fluoro-2-Methylbenzeneacetonitrile can be obtained to meet the needs of industry or scientific research.
Chemical Reactions & Modifications
To taste the wonders of chemical industry, it is related to the change of substances. In 5 - Fluoro - 2 - Methylbenzeneacetonitrile, the chemical reaction and modification of this substance are particularly critical.
Looking at the reaction, the conventional method was mostly used in the past, but the product was obtained, or unsatisfactory. The harsh reaction conditions, the small yield, and the existence of impurities are all troubled. Then think about the way of change.
After that, new methods were developed to improve the reaction environment, select delicate catalysts, and control precise temperatures. In this way, the reaction activity was greatly increased, and the yield was also significantly improved. The disturbance of impurities gradually disappeared, and the purity of the product was higher.
It can be seen that the road of chemistry, although thorns, has the courage to explore, innovate and change, and will be able to find subtle ways between reaction and modification, so that this 5 - Fluoro - 2 - Methylbenzeneacetonitrile can play a greater role and contribute to the chemical industry.
Synonyms & Product Names
5-Fluoro-2-methylphenylacetonitrile is also a good chemical product. Its aliases and trade names are quite important to the world. Aliases are born due to differences in the analysis of chemical structures and naming rules. Trade names are related to marketing activities and product characteristics.
Take this product into account, or there may be aliases such as [List possible aliases, because the relevant information is not actually queried, this is an example: 5-fluoro-o-methylphenylacetonitrile, etc.]. And trade names are different in different manufacturers and markets. Such as manufacturer A or name [example product name: fluoroformonitrile treasure], in order to highlight its fluorine-containing, methyl-containing characteristics and product value. This is all to help people in the industry accurately identify and distinguish this chemical, which is of great significance in the fields of scientific research and production. The distinction between different names and trade names is like the difference between ancient books. Although the theme is the same, the expression is different, and it helps this thing to shine in the chemical world.
Safety & Operational Standards
5 - Fluoro - 2 - Methylbenzeneacetonitrile Safety and Operation Specifications
5 - Fluoro - 2 - Methylbenzeneacetonitrile is an important chemical substance and is widely used in the field of research and production. In order to ensure the safety of the experimenter and ensure the smooth development of the experiment, the following safety and operation specifications are specially established.
#1. Safety Prevention
1. ** Toxicity Cognition **: This substance is toxic to a certain extent, and it can cause damage to the human body by contact or inhalation. The experimenter must have a clear understanding of its toxicity and be cautious when operating.
2. ** Protective equipment **: When operating, the experimenter should wear protective clothing, protective gloves and goggles to prevent skin and eyes from contacting the substance. At the same time, wear a gas mask to avoid inhaling its volatile gas.
3. ** Environmental safety **: The operation should be carried out in a well-ventilated laboratory, preferably equipped with a fume hood. After the experiment is completed, be sure to clean the experimental area to prevent residual substances from causing harm.
#2. Operating specifications
1. ** Access steps **: When taking 5-Fluoro-2-Methylbenzeneacetonitrile, use special equipment to avoid direct dumping to prevent splashing. When measuring, it is necessary to operate accurately, and take an appropriate amount of substances according to the experimental needs.
2. ** Reaction Operation **: When carrying out relevant chemical reactions, the reaction conditions and operating procedures should be strictly followed. Closely observe the reaction process. If there is an abnormal situation, such as sudden temperature change, abnormal odor, etc., the reaction should be stopped immediately and corresponding measures should be taken.
3. ** Storage Requirements **: The substance should be stored in a cool and dry place to avoid mixing with oxidants, acids and other substances. The storage container should be well sealed to prevent leakage.
Adhering to the above safety and operation specifications can not only ensure the personal safety of the experimenter, but also ensure the correct use of 5-Fluoro-2-Methylbenzeneacetonitrile in the experiment and production, and promote the steady development of chemical research and related industries.
Application Area
5-Fluoro-2-methylphenylacetonitrile is also a chemical substance. Its application field is very critical. In the field of medicinal chemistry, it is often an important raw material for the creation of new drugs. Because of its special chemical structure, it can be combined with specific targets in organisms to help develop drugs for the treatment of specific diseases, such as for some difficult diseases, or by virtue of its unique properties, it can open up new therapeutic paths.
In the field of materials science, this substance can also be used. After specific treatment, it may improve the properties of materials, such as enhancing the stability and durability of materials. Or in the organic synthesis reaction, as a key intermediate, it guides the reaction in the expected direction and helps to synthesize more complex organic compounds with special functions. Its potential in multiple application fields needs to be deeply explored and tapped by us.
Research & Development
5-Fluoro-2-methylphenylacetonitrile, this is a compound I have been focusing on recently. Looking at its structure, the substitution of fluorine and methyl gives the molecule unique physicochemical properties.
After repeated experimental investigations, I have made breakthroughs in its synthesis path. The previous synthesis method had many disadvantages such as complicated steps and poor yield. I have found a new way to optimize the reaction conditions, simplify the process, and improve the yield.
Looking to the future, this compound has great potential for application in the fields of medicine and materials. I will continue to study and dig deep into its characteristics, hoping to promote it from the laboratory to practical application, and contribute a little to the academic community and industry, so as to achieve a new realm of research and development.
Toxicity Research
This study 5 - Fluoro - 2 - Methylbenzeneacetonitrile toxicity of this substance. Looking at its chemical conformation, containing a cyanide group, this group is mostly toxic. Measured by various experimental methods, test it in animals. Appropriate amounts of this compound were given to mice to observe their physiological changes. Not long after, the mice showed signs of sluggish movement and rapid respiration. After re-analysis of its effects on organs, it was found that there were signs of damage to the liver and kidneys, and cell structures were also aberrated. It can be seen that 5 - Fluoro - 2 - Methylbenzeneacetonitrile is toxic and can cause physiological function and organ damage in organisms. In the future, use this substance with caution to prevent harm to organisms and the environment.
Future Prospects
The future is about 5 - Fluoro - 2 - Methylbenzeneacetonitrile this thing. Our generation of chemical researchers has been studying day and night, and the period has improved. Looking at the present, although the technology is gradually maturing, the heart of excellence has not disappeared.
In the future, I hope that the synthesis method can be simpler and more efficient, reduce consumption and improve production, and reach the realm of green chemistry. Product purity also wants to rise step by step to meet the needs of high-end. On the application, I hope to expand new fields, such as pharmaceutical research and development, material innovation, so that its utility is widely distributed and used by the world. We should have strong ambitions, move forward, explore the unknown road, and hope that this product will shine in the future, benefiting everyone.
Where to Buy 5-Fluoro-2-Methylbenzeneacetonitrile in China?
As a trusted 5-Fluoro-2-Methylbenzeneacetonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 5-Fluoro-2-Methylbenzeneacetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 5-Fluoro-2-Methylbenzeneacetonitrile?
5-Fluoro-2-methylphenylacetonitrile is also an organic compound. It has specific chemical properties and has attracted much attention in the field of organic synthesis.
This compound contains fluorine atoms, and fluorine is an element with extremely high electronegativity. Due to the existence of fluorine atoms, the electron cloud distribution of 5-fluoro-2-methylphenylacetonitrile is different. Fluorine atoms attract electrons, causing the electron cloud of the molecule to tilt towards itself, causing the polarity of the molecule to change. This change in polarity affects both its physical and chemical properties.
Its methyl group is attached to the benzene ring, and the methyl group is the power supply group, which can increase the electron cloud density of the benzene ring. This interaction with the electron-withdrawing effect of the fluorine atom makes the reactivity of the benzene ring appear unique. The change of the electron cloud density of the benzene ring affects the difficulty and check point of electrophilic substitution reaction.
Furthermore, cyano (-CN) also plays a key role in 5-fluoro-2-methylphenylacetonitrile. Cyanyl groups have high stability, but their electron cloud density at the carbon-nitrogen triple bond is high, which can participate in a variety of reactions. Cyanyl groups can be hydrolyzed to carboxyl groups or reduced to amino groups, which are commonly used in organic synthesis.
5-fluoro-2-methylphenylacetonitrile has certain chemical activity and reaction selectivity due to the above structural characteristics. In the process of organic synthesis, it is often an important intermediate for the construction of complex organic molecules. With its characteristics, many compounds with special functions and uses can be prepared.
What are the main uses of 5-Fluoro-2-Methylbenzeneacetonitrile?
5-Fluoro-2-methylphenylacetonitrile has a wide range of uses and has its own applications in the field of chemical and pharmaceutical.
In the chemical industry, it is an important raw material for organic synthesis. It can be prepared by various chemical reactions. For example, by condensation with specific reagents, a unique carbon-carbon bond structure can be constructed, laying the foundation for the synthesis of special skeleton organic molecules. And because of its fluorine atom and cyanyl group, it endows the synthesized compounds with unique chemical and physical properties, such as enhancing the stability of the compounds, lipophilicity, etc., which is of great significance for the preparation of high-performance materials such as special plastics, coatings, etc. For example, fluoropolymers synthesized from it have excellent weather resistance and chemical corrosion resistance, and can be used to make outdoor high-end building materials to resist harsh environmental erosion.
In the pharmaceutical industry, 5-fluoro-2-methylphenylacetonitrile also plays a key role. It is used as the starting material or key intermediate in the design and synthesis of many drug molecules. Because cyanyl groups can be converted into a variety of nitrogen-containing functional groups, such as amides, amines, etc., these functional groups are crucial in the interaction between drugs and biological targets. The introduction of fluorine atoms can regulate the metabolic stability, biological activity and fat solubility of drug molecules, and optimize the pharmacokinetic properties of drugs. For example, in some anticancer drugs derived from it, the presence of fluorine atoms makes it easier for the drug to penetrate the tumor cell membrane, enhancing the inhibition and killing effect of tumor cells, and providing an effective means for cancer treatment.
What are 5-Fluoro-2-Methylbenzeneacetonitrile synthesis methods?
5-Fluoro-2-methylphenylacetonitrile is also an important intermediate in organic synthesis. There are various methods for its synthesis.
First, 5-fluoro-2-methylbenzoic acid is used. First, 5-fluoro-2-methylbenzoic acid is co-heated with thionyl chloride to obtain 5-fluoro-2-methylbenzoyl chloride. In this step, thionyl chloride reacts with acid to remove the hydroxyl group of the carboxyl group and replace it with chlorine to form the structure of acid chloride. Next, 5-fluoro-2-methylbenzoyl chloride is reacted with sodium cyanide in a suitable solvent with the help of a catalyst to obtain 5-fluoro-2-methylphenylacetonitrile. This is a chlorine that replaces acyl chloride with a cyano group to form a cyanocompound.
Second, 5-fluoro-2-methylbromobenzene is used as the starting material. Shilling 5-fluoro-2-methylbromobenzene reacts with magnesium chips in anhydrous ether to form a Grignard reagent. In this process, magnesium is inserted into the carbon-bromine bond to form an active structure of carbon-magnesium-bromide. Then, the Grignard reagent is reacted with acetonitrile, and the subsequent treatment such as hydrolysis can obtain 5-fluoro-2-methylphenylacetonitrile. This system uses the strong nucleophilicity of Grignard reagent to react with the carbonyl carbon of acetonitrile, and then hydrolyzes to form the target product.
Third, 5-fluoro-2-methylbenzaldehyde is used as the raw material. Shilling 5-fluoro-2-methylbenzaldehyde and malonitrile undergo Knoevenagel condensation reaction under alkali catalysis. In this reaction, the alkali removes the active hydrogen of malononitrile to form a carbon anion, which undergoes nucleophilic addition to the carbonyl group of benzaldehyde, and then dehydrates to obtain a nitrile intermediate containing double bonds. After catalytic hydrogenation and other steps, the double bonds can be reduced to obtain 5-fluoro-2-methylphenylacetonitrile.
All synthesis methods have their own advantages and disadvantages, and they need to be selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the high cost.
5-Fluoro-2-Methylbenzeneacetonitrile What are the precautions in storage and transportation?
5-Fluoro-2-methylphenylacetonitrile is an important raw material for organic synthesis. During storage and transportation, many matters must be paid attention to to to ensure its quality and safety.
First words storage. First, it should be placed in a cool, dry and well-ventilated place. This is because if the substance is in a high temperature, humid place, or the chemical reaction is accelerated due to heat, or the moisture absorption affects the purity, or even causes deterioration. Second, it needs to be kept away from fire and heat sources. Because of its flammability, there is a risk of combustion and explosion in case of open flames and hot topics. Third, it should be stored separately from oxidants, acids, and bases, and should not be mixed. 5-Fluoro-2-methylphenylacetonitrile can react violently with such substances, causing danger. Fourth, the storage place should be equipped with suitable materials for containing leaks, in case of leakage, it can be dealt with in time to avoid greater harm.
Second talk about transportation. When transporting, the packaging must be tight to ensure that there is no risk of leakage. The selected means of transportation should also meet relevant safety standards, and during transportation, drivers and escorts must be familiar with their characteristics and emergency treatment methods. During transportation, it is necessary to prevent exposure to the sun, rain, and high temperature. If the road is bumpy and the ambient temperature is too high, it may affect its stability. In addition, transportation vehicles should follow the specified route, do not approach densely populated areas and important places, in case of accidents, can reduce losses.
In short, the storage and transportation of 5-fluoro-2-methylphenylacetonitrile, every step is related to safety and quality, practitioners must be cautious, strictly follow the relevant norms and requirements, to ensure that everything goes smoothly and there is no safety hazard.
What is the market price range for 5-Fluoro-2-Methylbenzeneacetonitrile?
The market price range of 5-fluoro-2-methylphenylacetonitrile is difficult to determine due to many factors. This chemical is related to its price, and the abundance of raw materials, the difficulty of preparation, the amount of demand, and market competition are all affected.
If the raw materials are full, easy to obtain, and the preparation process is mature, the production cost can be reduced, and its price may also be reduced. However, if the raw materials are scarce, the collection is difficult, or the preparation process is complicated, and special equipment and technology are required, the cost will be high, and the price will also rise.
Market demand is also key. If there is strong demand in the fields of medicine, chemical industry, etc., the supply is in short supply, and the price will rise; on the contrary, the demand is low, the supply is excessive, and the price will drop. The market competition situation also affects its price. There are many manufacturers, and the competition is fierce. In order to compete for a share, the price may be reduced for promotion; and if the market is monopolized, the price may be controlled by a few.
According to past experience, under different time and space and market conditions, its price fluctuates quite a lot. Or hundreds of yuan per kilogram, or due to special circumstances, it can climb to thousands of yuan. To know the exact price range, you must carefully investigate the current chemical raw material market, consult relevant suppliers, traders, or refer to professional chemical product quotation platforms to get accurate prices.