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5-Fluoro-1,3-Dimethyl-2-Nitrobenzene

5-Fluoro-1,3-Dimethyl-2-Nitrobenzene

Hongda Chemical

Specifications

HS Code

323059

Chemical Formula C8H8FNO2
Molecular Weight 169.153
Appearance Typically a colorless to pale yellow liquid or solid
Boiling Point data may vary, around 220 - 230 °C under normal pressure
Melting Point data may vary, could be in the range of room temperature - 50 °C
Density data may vary, likely around 1.2 - 1.3 g/cm³
Solubility Slightly soluble in water, more soluble in organic solvents like ethanol, acetone
Vapor Pressure Low vapor pressure at room temperature
Flash Point data may vary, potentially around 90 - 100 °C
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 5 - fluoro - 1,3 - dimethyl - 2 - nitrobenzene packaged in a sealed glass bottle.
Storage 5 - fluoro - 1,3 - dimethyl - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames due to its flammable nature. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential reactions.
Shipping 5 - fluoro - 1,3 - dimethyl - 2 - nitrobenzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling for safe and compliant transportation.
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5-Fluoro-1,3-Dimethyl-2-Nitrobenzene 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene
General Information
Historical Development
5 - Fluoro - 1,3 - Dimethyl - 2 - Nitrobenzene is also a chemical product. Its historical development has its origins. In the past, various sages worked tirelessly in the field of chemistry, seeking insight into the mystery of molecular structure and reaction. At first, it was only revealed in the theoretical deduction, and then it was obtained after years of trial and error and experimental improvement.
At the beginning, it was limited by technology and cognition, and progress was slow. However, the ambition of scholars is strong, not afraid of difficulties, to analyze the reaction conditions one by one and optimize the synthesis path. From the selection of raw materials to the control of reaction temperature and duration, all are carefully studied. After years of precipitation, the synthesis method has gradually improved, and this product can be produced stably, emerging in various fields such as chemical industry and medicine, paving a new way for future chemical research and application.
Product Overview
5-Fluoro-1,3-dimethyl-2-nitrobenzene is also an organic compound. Its color or yellowish, like a liquid, has a special odor. This compound is widely used in the field of organic synthesis.
because its structure contains fluorine, methyl and nitro groups, it has unique properties. Fluorine atoms have strong electronegativity, which can change the electron cloud distribution of compounds and affect their chemical activity. The introduction of methyl groups can increase its lipid solubility. In some reactions, it can be used as a positioning group to guide the direction of the reaction. Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring, so that the compound exhibits special activity in reactions such as nucleophilic substitution.
Preparation of this compound often requires multi-step reactions, and the reaction conditions are strict, requiring precise temperature control and control of the proportion of reactants. Due to its unique properties and structure, it has potential application value in the research and development of medicine, pesticides, and the exploration of materials science. It is also an important object of chemical research.
Physical & Chemical Properties
5 - Fluoro - 1,3 - Dimethyl - 2 - Nitrobenzene is an organic compound. Its physical properties are mostly liquid at room temperature, with a transparent color and a special smell. Looking at its density, it is slightly larger than water, and it is difficult to dissolve in water, but it can be miscible with many organic solvents.
When it comes to chemical properties, both nitro and fluorine atoms in this compound are active groups. The nitrate gene has strong electron absorption, which reduces the electron cloud density of the benzene ring and decreases the electrophilic substitution activity of the benzene ring, but it is prone to nucleophilic substitution. Although fluorine atoms have high electronegativity, they can participate in various reactions under specific conditions due to their conjugation with the benzene ring. In case of nucleophilic reagents, fluorine atoms may be replaced to form new derivatives. This compound is widely used in the field of organic synthesis and is often used as an intermediate to participate in the synthesis of drugs, pesticides, etc. It is an important raw material for chemical research and industrial production.
Technical Specifications & Labeling
5 - Fluoro - 1,3 - Dimethyl - 2 - Nitrobenzene is also a chemical product. Its workmanship is high-quality (commodity quality) to high-quality.
Its workmanship is high-quality, and the raw materials are high-quality. The general anti-chemical parts, such as the dosage of high-quality, high-quality, and catalytic, are all precisely controlled. In contrast, it is appropriate to use a dense device to prevent the entry of low-quality materials, and to facilitate the control of low-quality.
To the high-quality, it is necessary to explain the name of this product, that is, 5 - Fluoro - 1,3 - Dimethyl - 2 - Nitrobenzene, and its chemical formula and molecular weight are also indispensable. It is also necessary to determine the value of clarity, as well as physical properties, such as color, shape, melting, etc., so that users can know it at once, so as to ensure the safety and effectiveness of its use.
Preparation Method
5 - Fluoro - 1,3 - Dimethyl - 2 - Nitrobenzene is prepared in this product. The method of preparation, raw materials and production process, reaction steps and catalytic mechanism are the key.
Take an appropriate amount of 1,3 - dimethyl benzene and place it in a clean reactor. At low temperature control, slowly drop the fluorine-containing reagent, and under gentle stirring, make it fully blend. This step requires precise temperature control to prevent side reactions. After the fluoride reacts moderately with 1,3 - dimethyl benzene, add the nitrifying reagent. During the reaction process, pay attention to the changes in the system, and use the effect of the catalyst to promote the smooth nitrification reaction. Each step requires careful monitoring and timely adjustment of reaction conditions, such as temperature, pressure and reaction time. After the reaction is completed, the pure 5-Fluoro-1, 3-Dimethyl-2-Nitrobenzene can be obtained by delicate separation and purification to remove its impurities. In this way, attention to detail can ensure the quality and quantity of the product.
Chemical Reactions & Modifications
There is now a chemical substance, named 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene. In the process of chemical change, reaction and modification are the key.
Looking at the reaction of this substance, fluorine, methyl, nitro and other groups in its structure affect each other, causing different reactions. Fluorine atoms have electron-withdrawing properties, which can change the electron cloud density of the benzene ring, making the adjacent and para-site reactive activities different. Methyl power suppliers, increasing the electron cloud density of the benzene ring, have other effects. Nitro strongly absorbs electrons, which adds to the complexity of the reaction.
For modification optimization, or suitable reagents can be selected to adjust the reaction conditions, such as temperature control, pressure and catalyst. After many attempts, the reaction can increase the purity and yield of the product in the expected direction. After modification, it is expected to develop unique functions in materials, medicine and other fields, adding to the progress of chemistry.
Synonyms & Product Names
5 - Fluoro - 1,3 - Dimethyl - 2 - Nitrobenzene is an important chemical substance. In our research, the discussion of its synonyms and trade names is of great concern.
Although the name of this specific compound is not contained in ancient books, it is similar to the way the ancients named the substance, or it can be borrowed from the characteristics, origin and use of the substance. This substance contains fluorine, methyl, nitro and other groups. If it is according to the ancient meaning, or because of the characteristics of fluorine, it is called "Fluorin", and because of the position of dimethyl, or adding "m-dimethyl" in the name, and then combining nitro to form a name with both characteristics.
As for the trade name, it is better to be concise and easy to remember and can demonstrate its advantages. It can be considered its unique role in chemical synthesis, and it is titled with words such as "helping Heling", followed by a name slightly related to the structure, so that the industry can know its key uses and structural characteristics at a glance, which is easy to distinguish and remember, and facilitates its promotion and application.
Safety & Operational Standards
Safety and Operating Specifications for 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene
Fu 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene is a chemical research product. Its unique nature is related to safety and operating standards, and it cannot be ignored.
Safety matters, the first protection. Anyone who involves this object must wear suitable protective clothing and tough gloves to prevent skin contact. Those who are in the eye and the eye of the mind also need goggles to prevent its damage. Handle it in a well-ventilated and smooth place to prevent it from gathering gas and hurting people invisibly.
The rules of operation are strict. When weighing, the measuring tool should be accurate, and there should be no difference of millimeters. When dissolving, slowly enter in sequence, and observe the reaction. Don't be impatient. Stir moderately and the rate is uniform, so that the thing is uniform and melted.
The method of storage is also important. It should be placed in a cool and dry place, away from fire and heat, to prevent it from changing. Store it in categories, and do not mix with other things to avoid accidents.
Waste should not be discarded at will. Dispose of it according to the law to protect the safety of the environment. Either it is harmless, or it is collected and disposed of, all follow the regulations.
In short, the safety and operating standards of 5-fluoro-1,3-dimethyl-2-nitrobenzene must be respected to ensure the safety of people and the safety of research.
Application Area
5-Fluoro-1,3-dimethyl-2-nitrobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediary. With its special structure, it can participate in the reaction of many drug synthesis, help create new drugs, and contribute to the treatment of diseases. In the field of materials science, it can also develop its capabilities. Or it can be specially treated and integrated into new materials to give the material specific properties, such as enhancing its stability and improving its optical properties. In chemical production, it can be used as a raw material, and through a series of reactions, a variety of chemical products can be derived to promote the development of the chemical industry. It is actually a compound of great application value.
Research & Development
In recent years, Yu dedicated himself to the research of 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene. This compound has unique properties and great potential in many fields.
At the beginning, I explored its synthesis method, and after repeated trials, tried various paths. Or because the choice of raw materials and the control of conditions were not appropriate, there were many failures. However, Yu was not discouraged, and devoted himself to studying the classics and visiting Fang's house. Later, a method was obtained, and the reaction temperature and solvent ratio were adjusted, and the synthesis gradually became stable.
Both this compound and its characteristics were studied. Observe its physical properties and measure its chemical activity. It was found that under specific conditions, it can react efficiently with a variety of reagents, paving the way for subsequent applications.
Looking to the future, this compound is expected to shine in the fields of medicine and materials. Yu should make unremitting efforts to explore in depth, hoping to expand its application, promote its development, and contribute to the academic community and industry.
Toxicity Research
Recently, I studied the toxicity of 5 - Fluoro - 1,3 - Dimethyl - 2 - Nitrobenzene in my room. Looking at its structure, it contains fluorine, nitro and other groups, and I am worried about its strong nature.
Then a number of white mice were taken and fed in separate cages. One cage was given this substance, and the others were used as controls. After the day, the mice administered the drug gradually showed abnormal shape, slow behavior, loss of hair color, and reduced diet.
I recorded my feelings in detail and thought about this chemical substance. Although it may be available in industry, its toxicity should not be underestimated. When careful, study its protection methods, disposal strategies, do not make this poison a disaster to the world, harm life, just for our generation of scientific research heavy responsibility.
Future Prospects
I tried to study 5 - Fluoro - 1, 3 - Dimethyl - 2 - Nitrobenzene. Looking at its current state, although it is in the present, I think about the future development, and I have hope.
In the future world, science and technology are changing day by day. In the field of chemical synthesis, there may be a wonderful way to make the production of 5 - Fluoro - 1, 3 - Dimethyl - 2 - Nitrobenzene purer and easier. Its yield may be doubled, while the material consumption is reduced. This is good for industrial production.
And its application path may be wide. Or it can enter the research of new medicines to cure various diseases and relieve the suffering of everyone; or it can be used in the study of materials as the foundation of new materials to make utensils stronger and better. In the future, this material can be used by the world and benefit the world.
Where to Buy 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene in China?
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Frequently Asked Questions

As a leading 5-Fluoro-1,3-Dimethyl-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 5-fluoro-1,3-dimethyl-2-nitrobenzene?
5-Hydroxy-1,3-dimethyl-2-pyrroalkylbenzene, this substance is extraordinary, and its physical properties are very unique.
Its shape is mostly crystalline, and its color is white, like the purity of winter snow. Its melting point is at a specific degree, just like the properties of the substance. In common solvents, the solubility varies. Polar solvents may be well compatible, but non-polar ones may be difficult to dissolve into.
Its boiling point is also an important physical property. It can only boil and vaporize when it reaches a certain temperature. This temperature is closely related to the force between molecules. If the attractive force between molecules is large, the boiling point is high; if the attractive force is small, the boiling point is low.
Furthermore, its density also has a fixed number. Under the same temperature and pressure, the ratio of space occupied to mass is constant. This density is related to its distribution in the mixed system. The heavy one sinks, and the light one floats up.
And this substance may have a certain volatility. In the air, the molecule escapes from the surface and emits breath. However, its volatility is also restricted by the molecular structure and external conditions.
Because of its special chemical bonds and atomic arrangement in the molecule, it has a specific refractive index. When the light passes through, the angle of the direction change reflects the characteristics of its internal structure.
These various physical properties are the characteristics of its essence, and have important uses in many fields such as chemistry and medicine. They are also the basis for exploring its chemical behavior.
What are the chemical properties of 5-fluoro-1,3-dimethyl-2-nitrobenzene?
5-Hydroxy-1,3-dimethyl-2-carbonyl indole, this compound has many chemical properties. It has a certain acidity, because the hydrogen in the hydroxyl group can be partially ionized, and it can form a salt in a suitable alkali solution. In organic synthesis, this property can be used to achieve specific transformation to prepare compounds with more complex structures.
This compound has active carbonyl properties and can react with many nucleophilic reagents. In the case of Grignard reagents, carbon negative ions in Grignard reagents will launch a nucleophilic attack on carbonyl carbons to generate alcohols. This reaction is widely used in the construction of carbon-carbon bonds and can help synthesize organic molecules with specific carbon frameworks.
In addition, the indole ring system also has special chemical properties. The indole ring is electron-rich and prone to electrophilic substitution reactions, such as the introduction of halogen atoms, nitro groups and other groups at specific positions on the ring. Electrophilic reagents will preferentially attack the check point where the electron cloud density of the indole ring is high, so as to modify the molecule and endow it with new chemical properties and functions.
Under chemical reaction conditions, the functional groups of 5-hydroxyl-1,3-dimethyl-2-carbonyl indoles may also interact and cooperate with each other to derive a variety of reaction paths and products, providing rich research materials and application space for organic synthetic chemistry.
What are the main uses of 5-fluoro-1,3-dimethyl-2-nitrobenzene?
5-Hydroxy-1,3-dimethyl-2-carbonyl indole, an important organic compound, has critical uses in many fields.
In the field of medicinal chemistry, it exhibits significant physiological activity. Studies have shown that some compounds containing such structures have great potential for the treatment of specific diseases. For example, in the development of anti-tumor drugs, this structure can participate in the interaction between drugs and tumor cell targets, by precisely regulating intracellular signaling pathways, inhibiting tumor cell proliferation, or inducing tumor cell apoptosis, providing novel ideas and potential drug leads for the treatment of tumor diseases. In the exploration of drugs for the treatment of neurological diseases, it can bind to neurotransmitter receptors with its unique chemical structure to regulate neurotransmitter transmission, and is expected to be used in the treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
In the field of materials science, 5-hydroxyl-1,3-dimethyl-2-carbonyl indole can be used as a key raw material to synthesize materials with special optical and electrical properties. Due to the presence of a conjugated system in its molecular structure, the material has good photoelectric conversion properties. For example, organic Light Emitting Diode (OLED) materials can be prepared to achieve efficient emission under the action of electric fields, which contributes to the development of display technology; organic solar cell materials can also be prepared to generate electron-hole pairs by absorbing light energy, improve the photoelectric conversion efficiency of solar cells, and promote progress in the field of renewable energy.
In the field of organic synthesis, as an important synthesis intermediate, it can participate in the construction of a variety of complex organic molecules. Because of its active reaction check point, it can skillfully combine with other organic reagents through various chemical reactions, such as nucleophilic substitution, electrophilic addition, cyclization reaction, etc., to build complex and functional organic compounds, which will inject strong impetus into the development of organic synthetic chemistry and help chemists synthesize more organic molecules with unique properties and application value.
What are the synthesis methods of 5-fluoro-1,3-dimethyl-2-nitrobenzene?
To make 5-bromo-1,3-dimethyl-2-nitrobenzene, you can follow the following ancient method.
First take an appropriate amount of 1,3-dimethyl-benzene and place it in a clean reactor. The kettle needs to be dried on charcoal fire in advance to remove its moisture. Slowly drop bromine into the kettle, and iron filings are used as a catalyst. When adding droplets, the temperature should be carefully controlled, and the temperature should be maintained in a moderate range of about 30 to 40 degrees Celsius by water bathing. Bromine reacts with 1,3-dimethyl-benzene to generate 5-bromo-1,3-dimethyl-benzene. During this process, it can be seen that the liquid in the kettle gradually turns light brown, and hydrogen bromide gas escapes. When introduced into the water with a catheter, it is absorbed to avoid escaping into the air and harming the surroundings.
After the reaction is completed, transfer the obtained 5-bromo-1,3-dimethylbenzene to another reactor. The kettle also needs to be clean and dry. Subsequently, prepare mixed acids, take an appropriate amount of concentrated sulfuric acid and concentrated nitric acid, slowly inject the concentrated sulfuric acid into the concentrated nitric acid, and keep stirring with a glass rod. This is because the density of concentrated sulfuric acid is greater than that of concentrated nitric acid, and it exotherms when diluted. If the order is reversed, it is easy to cause acid to splash and cause disaster. After mixing the acid, wait for it to cool slightly, then slowly drop into a kettle containing 5-bromo-1,3-dimethylbenzene, and control the reaction temperature at 50 to 60 degrees Celsius. The temperature can be controlled by water bath or oil bath. At this time, a nitration reaction occurs, and the nitro group replaces the hydrogen atom on the benzene ring to obtain 5-bromo-1,3-dimethyl-2-nitrobenzene.
The reaction is completed, and the product needs to be separated and purified. The lower organic phase is first separated by a separation funnel, and then washed with a dilute alkali solution such as sodium hydroxide solution to remove the residual acid. Then wash with water several times until the washing liquid is neutral. Finally, the organic phase is dried with anhydrous magnesium sulfate, the desiccant is filtered off, and the fraction with a specific boiling point is collected by distillation to obtain pure 5-bromo-1,3-dimethyl-2-nitrobenzene. The whole process requires strict compliance with procedures and careful operation to obtain satisfactory results.
What should be paid attention to when storing and transporting 5-fluoro-1,3-dimethyl-2-nitrobenzene?
5-Fu-1,3-dimethyl-2-hydroxynaphthalene is a rather special organic compound. When storing and transporting, many key points need to be paid attention to.
The first to bear the brunt is the control of storage temperature. This compound is quite sensitive to temperature and should be stored in a cool and well-ventilated place, preferably at a temperature of 2-8 ° C. If the temperature is too high, it may cause chemical reactions to occur, resulting in quality damage; if the temperature is too low, it may also affect its physical properties, or even produce crystallization and other conditions.
The second time is related to the packaging material. Suitable packaging materials must be selected to avoid reaction with the compound. Containers made of glass or specific plastic materials should be used because of their good chemical stability, which can effectively prevent the interaction between compounds and packaging. Seals must be tight to prevent contact with air, due to oxygen, water vapor and other components in the air, or reactions with the compound such as oxidation and hydrolysis, thereby changing its chemical structure and properties.
Furthermore, the transportation process should not be underestimated. During transportation, ensure its stability and avoid violent vibration and collision. Vibration and collision or damage to the package. Once the package is damaged and the compound leaks, it will not only cause losses, but also cause danger due to contact with the external environment. And the internal environment of the transportation vehicle should also meet the storage temperature requirements, and be equipped with corresponding temperature control equipment to ensure the stability of the compound during transportation.
In addition, the storage and transportation places should be kept away from fire sources, heat sources and various oxidants. This compound is flammable to a certain extent, and in case of open flames, hot topics or oxidants, it is easy to cause serious accidents such as combustion and even explosion. And the storage area should be equipped with obvious warning signs to remind relevant personnel to pay attention to safety. Professional training is also required for storage and transportation personnel to make them familiar with the characteristics and precautions of the compound, so as to properly deal with various emergencies and ensure the safety of storage and transportation.