5-Cyano-2-fluorobenzenesulfonamide has a wide range of uses. In the field of pharmaceutical and chemical industry, it is often a key raw material for the creation of new drugs. This compound has unique chemical properties and can precisely combine with specific targets in organisms. By adjusting the molecular structure, it can develop drugs against specific diseases, such as anti-tumor and anti-viral drugs, to help patients recover.
In the field of materials science, it also has outstanding performance. It can be used as a synthetic intermediate for special functional materials. After specific reactions, it endows materials with special properties such as high stability and strong conductivity, paving the way for the research and development of new materials. It is widely used in electronic, optical materials and other fields to promote the upgrading of scientific and technological products.
Furthermore, in the field of agricultural chemistry, 5-cyano-2-fluorobenzenesulfonamide can be made into high-efficiency and low-toxicity pesticides. Using its chemical activity to target specific pests and diseases can not only effectively prevent and control, but also reduce the harm to the environment, help the green and sustainable development of agriculture, protect the robust growth of crops, and ensure food security.

The synthesis methods of 5-cyano-2-fluorobenzenesulfonamide are many different, and the following is your detailed description.
First, 2-fluoro-5-nitrobenzenesulfonamide is used as the starting material. First, the raw material is reacted with cyanide reagents, such as cuprous cyanide, under suitable reaction conditions. This reaction requires an organic solvent, such as N, N-dimethylformamide (DMF), in the state of heating, after several times, the nitro group can be replaced by a cyano group to form 5-cyano-2-fluorobenzenesulfonamide. In this process, the reaction temperature needs to be carefully controlled. If it is too high, side reactions will increase, and if it is too low, the reaction rate will be slowed.
Second, 2-fluorobenzenesulfonyl chloride can also be used as the starting material. First, it reacts with ammonia to obtain 2-fluorobenzenesulfonamide. Then, in the presence of a suitable catalyst, it reacts with a cyanide reagent. Commonly used catalysts include palladium-based catalysts. In the presence of a suitable base, such as potassium carbonate, the reaction is heated in an organic solvent. This reaction condition is more severe, and it is necessary to precisely control the pH, temperature, reaction time and other factors of the reaction system to obtain a higher yield of 5-cyano-2-fluorobenzenesulfonamide.
Third, take 2-fluoro-5-halobenzenesulfonamide as the starting material. Here the halogenated group can be chlorine, bromine, etc. It reacts with the cyanide reagent with the help of a phase transfer catalyst. The phase transfer catalyst can promote the reaction to proceed efficiently in the two-phase system. React in a suitable temperature and solvent environment, and after a certain period of time, the halogen atom is replaced by a cyanyl group to form the target product. This method requires attention to the type and dosage of phase transfer catalysts, as well as the choice of reaction solvent, because these factors have a significant impact on the process and yield of the reaction.
The above synthesis methods have their own advantages and disadvantages. In actual operation, it is necessary to choose carefully according to factors such as the availability of raw materials, cost, and difficulty of reaction conditions.

5-Cyano-2-fluorobenzenesulfonamide, this is an organic compound. Its physical properties are unique, let me tell you in detail.
Looking at its appearance, it is often a white to off-white crystalline powder with a fine texture. It may have a faint luster in the sun, just like a fine pearl, exuding a unique charm.
As for the smell, it does not have a strong pungent smell. It is mostly a weak and special smell, but it will not cause strong stimulation to the sense of smell. The smell is like a gentle breeze blowing, elegant and not flamboyant.
Talking about solubility, it has a certain solubility in common organic solvents, such as methanol and ethanol. In methanol, with the increase of temperature, the dissolution rate accelerates, just like ice and snow in the warm sun, slowly melting, and gradually forming a homogeneous solution. In water, its solubility is relatively poor, just like stubborn stones entering the water, only a small amount can be dispersed in it, and it is difficult to completely melt.
Melting point is also one of the important physical properties. After determination, its melting point is within a specific range. This property is like the "ID card" of a substance, providing a key basis for identification and purification. During the heating process, when it reaches a specific temperature, it gradually converts from solid to liquid, and this transition process is smooth and orderly. The density of 5-cyano-2-fluorobenzenesulfonamide is moderate, and it is neither as frivolous as a feather nor as heavy as lead in similar compounds. Its density is determined by the molecular structure and composition, which is like the cornerstone of a building, laying the basic physical properties of the substance.
The above is the main physical properties of 5-cyano-2-fluorobenzenesulfonamide, which are all important clues for in-depth understanding of the compound. It is of great significance in many fields such as scientific research and industrial applications.

5-Cyano-2-fluorobenzenesulfonamide is an organic compound with unique chemical properties. Its appearance is often in the form of a white to off-white crystalline powder, which is crucial for identification and operation.
From a chemical activity point of view, cyano (-CN) and sulfonamide groups (-SO 2O NH 2O) give the compound significant reactivity. Cyanyl groups are nucleophilic and electrophilic, and can participate in many reactions, such as hydrolysis reactions. Under the catalysis of acids or bases, cyanyl groups can be converted into carboxyl groups (-COOH), thereby generating 5-carboxyl-2-fluorobenzenesulfonamide; or participate in nucleophilic addition reactions, react with compounds containing active hydrogen, and expand the molecular structure.
Sulfonamide groups, sulfur atoms have lone pair electrons, which can participate in the formation of hydrogen bonds and affect the solubility of compounds and intermolecular interactions. This group is also weakly acidic, and under strong base conditions, it can lose protons to form corresponding salts, which affects the solubility and stability of compounds. The fluorine atom at the
2-position has a high electronegativity and an electron-absorbing induction effect, which reduces the electron cloud density of the benzene ring and changes the activity of the electrophilic substitution reaction of the benzene ring, usually making the electrophilic substitution reaction more likely to occur in the meso-position. The introduction of fluorine atoms also affects the lipid solubility of compounds, which has an effect on their absorption, distribution and metabolism in vivo.
In terms of solubility, 5-cyano-2-fluorobenzenesulfonamide is slightly soluble in water. Because the molecule contains polar groups, it can form hydrogen bonds with water, but the non-polar part of the whole molecule also affects the solubility; however, it is easily soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide, etc. This property is conducive to its dissolution and reaction operation in organic synthesis reactions.
In terms of stability, under conventional conditions, 5-cyano-2-fluorobenzenesulfonamide is relatively stable. However, in high temperature, strong acid, strong base or strong oxidant environment, decomposition or reaction may occur. For example, at high temperatures, cyano groups may undergo polymerization or other thermal decomposition reactions; under strong acids or bases, cyano groups and sulfonamide groups may hydrolyze. Therefore, store in a cool, dry and well-ventilated place, away from fire, heat and strong chemical reagents.

I look at your question, but I am inquiring about the price of 5-cyano-2-fluorobenzenesulfonamide in the market. However, this price often changes due to many reasons, and it is difficult to determine.
The price of materials in the city is primarily supply and demand. If there are many applicants for this item, and there are few suppliers, the price will increase; on the contrary, if the supply exceeds the demand, the price may decrease.
Furthermore, quality is also the main reason. Those with excellent quality often have a higher price than those with inferior quality. The price of 5-cyano-2-fluorobenzenesulfonamide with fine preparation, few impurities and high purity is unusually comparable.
The source channel also affects its price. Self-produced or because the cost is controllable, the price has an advantage; and through multi-layer resale, the price may increase the profit of resale, and become higher.
The price varies depending on the region. In prosperous cities, due to high operating costs, the price may be higher than in remote places.
To know the exact price of this item, you can visit the chemical materials trading platform, which may list the quotations of various companies, which can be compared. Or consult the supplier of chemical raw materials to inquire about the price and relevant transaction terms in detail. In this way, you can get a more accurate price.