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5-(Chloromethyl)-1,2,3-Trifluorobenzene

5-(Chloromethyl)-1,2,3-Trifluorobenzene

Hongda Chemical

    Specifications

    HS Code

    196887

    Chemical Formula C7H4ClF3
    Molecular Weight 180.55
    Appearance Colorless to light yellow liquid
    Boiling Point 162 - 164 °C
    Density 1.36 g/cm³
    Flash Point 51 °C
    Solubility In Water Insoluble
    Odor Characteristic odor

    As an accredited 5-(Chloromethyl)-1,2,3-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle packaging for 5-(chloromethyl)-1,2,3 - trifluorobenzene.
    Storage 5-(Chloromethyl)-1,2,3 -trifluorobenzene should be stored in a cool, well - ventilated area away from heat and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions. Ensure proper labeling for easy identification and safety.
    Shipping 5-(Chloromethyl)-1,2,3 -trifluorobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring safety during transit.
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    5-(Chloromethyl)-1,2,3-Trifluorobenzene 5-(Chloromethyl)-1,2,3-Trifluorobenzene
    General Information
    Historical Development
    In the past, there were wise men who studied the subtlety of chemical industry, focusing on one thing, named 5- (Chloromethyl) -1,2,3-Trifluorobenzene. At the beginning, the method of making it was not complete, and it was quite difficult to obtain it. However, the wise men did not let up, and over the years they studied it, and the method gradually became complete.
    First, everyone searched for understanding in the classics, explored the changes in the nature of things, and thought about the way to combine. Or watch the furnace on a cold night, and observe the subtlety of the heat; or observe it during the day, and seek the rise of purity. After several years, the process has advanced, and the output has also increased.
    The evolution of this thing shows that the ancestors were dedicated to their efforts, not afraid of difficulties, and hoped to preserve the wealth of intellectual property for future generations. Its contribution to the chemical industry, such as star pilotage, to create a new method for future generations, to obtain this good thing, in all industries are of great use, this is the legacy of previous studies.
    Product Overview
    5- (chloromethyl) -1,2,3-trifluorobenzene, an organic compound. Its color may be colorless to light yellow liquid, with a special odor. The physical properties of this substance, such as boiling point and melting point, are quite important in scientific research and production.
    The preparation method, or through a specific chemical reaction path, through several steps of reaction, to achieve the purpose of synthesis. The selection of raw materials, reaction conditions, such as temperature, pressure, catalyst use, etc., all have a significant impact on the yield and purity of the product.
    In the chemical industry, this compound can be used as an intermediate to prepare other fine chemicals. It may have potential application value in the pharmaceutical, pesticide and other industries. However, when using it, it is necessary to pay attention to its safety, as it may be toxic and irritating, and strict safety procedures must be followed during operation.
    Physical & Chemical Properties
    5- (chloromethyl) -1,2,3-trifluorobenzene is also an organic compound. Its physical and chemical properties are worth exploring.
    Looking at its physical properties, at room temperature, or as a colorless liquid, it has a special odor. Its boiling point, melting point, etc. are the keys to characterize its physical state. The boiling point is related to its gasification temperature, and the melting point shows the transition point between its solid state and its liquid state.
    In terms of its chemical properties, it contains chloromethyl and trifluorophenyl groups, and its activity is unique. Chloromethyl chloride atoms have a certain nucleophilic substitution activity and can interact with many nucleophilic reagents. The fluorine atoms of trifluorophenyl groups have strong electronegativity, which makes the distribution of molecular electron clouds different, affecting their reactivity and selectivity. This compound is used in the field of organic synthesis, or as a key intermediate, participating in various reactions to prepare other organic compounds, and is of great significance in chemical research and industrial production.
    Technical Specifications & Labeling
    5- (chloromethyl) -1,2,3-trifluorobenzene is also a new product of chemical. Its technical rules and standards (parameters of quotient) are related to the preparation and evaluation, which is of the utmost importance.
    The production of this product needs to follow the fine technical rules. The choice of materials should be pure and suitable; temperature and pressure should be carefully controlled. The reaction process should be slow and stable, and it should be prevented from mistakenly causing qualitative change.
    The method of learning should be judged by the standard. Looking at its color, it should be pure and transparent; measuring its boiling, the value should be in line with the standard. Moreover, according to the spectral analysis, the position and strength of the peak are all based on the rules, which must be in line with the rules of business ginseng, just to prove its quality. Only by following these rules and standards can we make good products to meet the needs of the world.
    Preparation Method
    The raw materials of this 5 - (chloromethyl) -1,2,3-trifluorobenzene are crucial to the production process, reaction steps and catalytic mechanism. First, take an appropriate amount of 1, 2, 3-trifluorobenzene as the base material, and add a specific proportion of chloromethylating reagents, such as a mixture of polyformaldehyde and zinc chloride, in a special container. The ratio of the two is precisely prepared according to the reaction.
    The temperature is controlled in a suitable range, about 80 to 100 degrees Celsius. This temperature range can promote the efficient progress of the reaction. During the reaction, it is necessary to stir at a specific frequency to fully contact the material. Wait for the reaction time to be set, about 3 to 5 hours, and monitor the progress of the reaction with an instrument until the reactant converts to the expected ratio, and then the reaction stops.
    Then, the product is purified by distillation and extraction to remove unreacted raw materials and by-products. During distillation, the temperature is controlled near the boiling point of the product to precisely separate. Extraction selects a suitable organic solvent to effectively separate the product from impurities, so that high purity of 5- (chloromethyl) -1,2,3-trifluorobenzene can be obtained.
    Chemical Reactions & Modifications
    In the field of Wenfu Chemistry, the reaction and modification of 5- (Chloromethyl) -1,2,3-Trifluorobenzene are related to the chemical industry and are quite important.
    Looking at its reaction, under various conditions, it has its own rules with other phases, or nucleophilic substitution, or addition genera. When nucleophilic, the properties of halogenated hydrocarbons are obvious, and chloromethyl is easily replaced by other groups, forming a new structure.
    As for modification, other groups can be introduced to change its properties. Or increase its solubility, or change its stability, and in different applications, each has its own ability. If adding the base of polarity, it can be improved in the solution of polar agents; adding the group of stabilization can strengthen its stability in various conditions.
    Chemists should carefully study the beauty of this reaction and modification in order to understand the rationale and contribute to the progress of chemical industry.
    Synonyms & Product Names
    5- (chloromethyl) -1,2,3-trifluorobenzene, its trade name, is of great importance to our research. Covering the same name can help us accurately identify and avoid the risk of confusion. And the trade name is not unique to the market.
    When we study this chemical, we often encounter the same shape. Or according to its shape, or its nature, can give different names. For example, 5- (chloromethyl) -1,2,3-trifluorobenzene, or according to its atomic arrangement and functionality. This same name, all refer to the same thing, but it means that it is heavy.
    As for the trade name, it is the name set by the company for its entry into the market. This name can recognize the characteristics and performance of the product, and help it to be used in the market. The trade name of 5- (chloromethyl) -1,2,3-trifluorobenzene also has this ability, so that the manufacturer and user can know the name, and or think about its specific use. Therefore, the same trade name is an important factor in the research, sale and use of 5- (chloromethyl) -1,2,3-trifluorobenzene.
    Safety & Operational Standards
    Safety and Operation Specifications for 5- (Chloromethyl) -1,2,3-Trifluorobenzene
    5- (Chloromethyl) -1,2,3-Trifluorobenzene, a new product of chemicals, has special properties and is widely used, but safety and operation regulations are of paramount importance.
    In storage, it is necessary to choose a cool and dry place to avoid heat and light exposure. Due to its sensitivity, high temperature or light intensity, it can cause qualitative change, which is very dangerous. And it is stored in a secret device to prevent leakage from the outside. If it leaks, it will harm the environment and endanger people.
    When operating, people must be well protected. Wear special clothes, gloves and masks. The clothes can be separated, the gloves can resist contact, and the mask prevents suction, and the body is safe. Operate in the common place to make the air smooth and avoid toxic accumulation. After use, the utensils must be cleaned, and the rest of the material should be properly placed, and it should not be discarded.
    If it leaks, deal with it quickly. Cut off the source first, prohibit fireworks, and prevent ignition and explosion. Keep away from people in the surrounding area. Suck it up with suitable materials, such as sand and vermiculite, and put it in a hazardous waste device, and deal with it according to regulations.
    In case of emergency, if it touches the skin, quickly rinse it with water, dye your clothes, and seek medical treatment. If it enters the eyes, when the water is long, seek medical help. If you inhale it, move it to an empty place, and if it is difficult to exhale, apply oxygen and send it to the hospital urgently.
    In short, the research and use of 5- (chloromethyl) -1,2,3-trifluorobenzene is based on safety and operation regulations. If you follow it, you can avoid risks and prosper in the industry; if you go against it, you will cause disasters and endless harm. Researchers must be careful, abide by regulations, and promote security.
    Application Area
    5- (chloromethyl) -1,2,3-trifluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs or have a healing effect on specific diseases. In material science, it can participate in the synthesis of materials with special properties, such as high stability and chemical corrosion resistance materials, which add its advantages to equipment and equipment. In the field of fine chemicals, it can be used as raw materials for the preparation of high-end chemicals and increase the quality and characteristics of products. It has a wide range of uses. With the advancement of scientific research, it will be able to emerge in more fields, contribute to the development of many industries and create new frontiers.
    Research & Development
    There is a chemical substance today, named 5- (Chloromethyl) -1,2,3-Trifluorobenzene. As a chemical researcher, I am known for the research and development of this substance.
    This substance has unique properties and has potential in chemical, pharmaceutical and other fields. After long-term research, we have understood some of its characteristics, but we still need to make unremitting exploration if we want to make it widely used.
    Our generation should use scientific methods to deeply analyze its structure and properties, and strive to find a way to optimize it. Or improve the preparation process to reduce its cost; or expand the scope of application and increase its value.
    We firmly believe that through continuous research and innovation, 5- (Chloromethyl) -1,2,3-Trifluorobenzene will be able to shine in many fields and contribute to the progress and development of society.
    Toxicity Research
    I am a chemist, and I am dedicated to the study of its toxicity. The properties of this thing are related to the safety of living beings and cannot be ignored.
    Looking at the structure of its molecules, chloromethyl is connected to the trifluorobenzene ring, and the structure is unique or has special chemical activity. According to common sense, halogenated bases may increase its toxicity. Its entry into the body of living things may disturb the metabolism of cells and disrupt the balance of biochemistry.
    However, the study of toxicity is not speculative. When based on experiments, observe its impact on various organisms, measure its semi-lethal amount, and observe its damage to organs and tissues. This research path is long and far-reaching, and it must be rigorous and scientific to explore the truth of its toxicity, so as to provide solid evidence for the world to prevent its harm and use its benefits.
    Future Prospects
    I have tried to research "5- (Chloromethyl) -1,2,3-Trifluorobenzene". Looking at its properties, it has specific properties and has extraordinary potential in various reactions.
    Looking to the future, it may be a key raw material for the creation of medicine. Due to its unique structure, it can lead to a variety of active molecules, which is expected to solve difficult diseases. And in material science, there is also a wide world. Or endow materials with new capabilities, such as excellent electrical conductivity and optical properties, to make new materials available for high-end technology.
    Although the road ahead is long, we researchers should move forward with enthusiasm and courage to explore its endless possibilities, hoping to create new horizons for future generations, so as to achieve great things and live up to the hope of the future.
    Where to Buy 5-(Chloromethyl)-1,2,3-Trifluorobenzene in China?
    As a trusted 5-(Chloromethyl)-1,2,3-Trifluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-(Chloromethyl)-1,2,3-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5- (Chloromethyl) -1,2,3-Trifluorobenzene?
    5- (Chloromethyl) - 1,2,3-trifluorobenzene is also an organic compound. It has a wide range of uses and has important applications in various fields of chemical industry.
    First, it is often a key intermediate in the synthesis of medicine. For the preparation of drugs with specific curative effects, the combination of chloromethyl and trifluorobenzene in its structure endows the molecule with unique chemical properties and reactivity. It can combine various organic reactions with other functional groups to build complex drug molecular structures, and then develop new drugs for specific diseases.
    Second, it also has important functions in the field of materials science. It can be used as a starting material for the synthesis of special performance polymer materials. By means of polymerization reaction or other chemical modification means, it is introduced into the polymer chain. With the characteristics of trifluorophenyl groups, such as good thermal stability, chemical stability and low surface energy, the polymer materials are endowed with excellent properties such as high temperature resistance, chemical corrosion resistance, and low friction coefficient. It is used in the manufacture of high-end engineering plastics, special coatings and other materials.
    Third, it is also indispensable in the creation of pesticides. Its structural characteristics can enable it to be derived from compounds with high insecticidal, bactericidal or herbicidal activities. Through rational molecular design and modification, the synergy effect of chloromethyl and trifluorobenzene can be used to develop environmentally friendly, efficient and low-toxicity new pesticides to meet the needs of modern agriculture for pest control.
    In summary, the unique molecular structure of 5- (chloromethyl) -1,2,3-trifluorobenzene is a valuable chemical raw material in many fields such as medicine, materials, and pesticides, promoting the sustainable development and innovation of related industries.
    What are the physical properties of 5- (Chloromethyl) -1,2,3-Trifluorobenzene?
    5 - (chloromethyl) - 1,2,3 -trifluorobenzene, is one of the organic compounds. Its physical properties are as follows:
    Under normal temperature and pressure, this substance is usually colorless to light yellow liquid, clear and translucent, if placed under light, it can be seen that it has a faint luster.
    When it comes to boiling point, it is within a certain temperature range. This temperature allows the force between molecules to be overcome just enough to change from liquid state to gaseous state. However, the exact boiling point value depends on the change of external pressure conditions. Generally speaking, under standard atmospheric pressure, the boiling point value can be accurately determined by experiment.
    As for the melting point, it is also a specific temperature point. When the temperature drops below this point, the thermal motion of the molecules weakens, and the arrangement of each other tends to be regular and orderly, so it condenses from the liquid state to the solid state.
    The density of this compound, compared to water, has a specific ratio. Its density reflects the compactness of the intermolecular packing, as well as the type and number of atoms composed.
    In terms of solubility, among common organic solvents such as ethanol, ether, and dichloromethane, 5- (chloromethyl) -1,2,3-trifluorobenzene exhibits good solubility. Because the organic solvent and the compound can interact through van der Waals forces, hydrogen bonds, etc., so that the molecules are uniformly dispersed. However, in water, its solubility is quite limited, which is due to the significant difference between the polarity of water and the polarity of the compound, and the weak interaction between the two.
    In addition, the volatility of the compound is also one of its physical properties. Under certain temperature and environmental conditions, its molecules tend to escape from the liquid surface to the gas phase. The strength of volatility depends on the size of the intermolecular force, as well as factors such as external temperature and air circulation.
    These physical properties of 5- (chloromethyl) -1,2,3-trifluorobenzene are of crucial significance in many fields such as organic synthesis and chemical analysis, laying the foundation for their practical application.
    What are the synthesis methods of 5- (Chloromethyl) -1,2,3-Trifluorobenzene?
    The synthesis method of 5- (chloromethyl) -1,2,3 -trifluorobenzene, often using trifluorobenzene as the starting material. First, the trifluorobenzene and the chloromethylation reagent, such as triformaldehyde and hydrogen chloride gas, are placed in a reaction vessel in the presence of a suitable catalyst, such as anhydrous zinc chloride. This is a classic chloromethylation reaction. The reaction temperature is controlled in a warm bath, so that it slowly undergoes electrophilic substitution. Chloromethyl is introduced into the benzene ring of trifluorobenzene to obtain the target product.
    In addition, an aromatic hydrocarbon containing a specific substituent is converted into trifluoromethyl through a series of reactions, and then the chloromethylation step is carried out. This path may involve multi-step reactions such as halogenation, cyano substitution, and trifluoromethylation. Each step requires precise regulation of reaction conditions, such as temperature, ratio of reactants, and reaction time, in order to improve yield and purity.
    is also synthesized using transition metal catalysis. Specific transition metal catalysts, such as palladium and copper complexes, are selected with corresponding ligands to react halogenated aromatics with chloromethylated reagents in specific bases and solvents. This method takes advantage of transition metal catalysis and has the characteristics of mild reaction conditions and good selectivity. However, the catalyst cost may be higher, and the reaction equipment and operation requirements are also strict.
    Furthermore, a well-designed organic synthesis route can be used to start from simple raw materials and convert target molecules through multi-step functional group transformation. For example, a simple organic compound containing fluorine and chlorine is used as the starting material to gradually build a benzene ring structure and introduce chloromethyl. Such route design requires in-depth understanding of the organic reaction mechanism, and each step of the reaction needs to be carefully optimized to achieve the purpose of efficient synthesis.
    What to pay attention to when storing and transporting 5- (Chloromethyl) -1,2,3-Trifluorobenzene
    5- (chloromethyl) - 1,2,3-trifluorobenzene is an organic chemical. When storing and transporting, many aspects need to be carefully paid attention to.
    When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. This substance is easily dangerous when heated. In case of open flame, it may cause combustion or even explosion. The temperature of the warehouse should be strictly controlled, and it should not be too high to prevent its chemical properties from being unstable due to temperature.
    Furthermore, it should be carefully isolated from other substances. Because of its certain chemical activity, it should not be mixed with oxidants, alkalis and other storage. Oxidants may react violently with it, and alkalis may also react chemically with it, resulting in dangerous situations.
    Packaging is also critical. Packaging must be tightly sealed to prevent its volatilization and leakage. If leakage occurs, it will not only pollute the environment, but also may cause harm to the human body. If the leaked substances come into contact with the skin and are inhaled into the respiratory tract, they may damage health.
    When transporting, the transportation vehicle must comply with relevant safety standards. It should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. During transportation, it is necessary to protect against exposure to the sun, rain and high temperature.
    Be careful during loading and unloading. Operators should wear suitable protective equipment and handle light to avoid damage to the container. Once the container is damaged and the material leaks, the consequences are unimaginable.
    In short, the storage and transportation of 5- (chloromethyl) -1,2,3-trifluorobenzene requires all-round consideration, and safety regulations are strictly followed to ensure that personnel safety and the environment are not endangered.
    What is the market price range for 5- (Chloromethyl) -1,2,3-Trifluorobenzene?
    The market price range of 5- (chloromethyl) -1,2,3-trifluorobenzene is difficult to determine with certainty. The market price of this compound often changes due to many factors.
    First, the price difference is quite large due to different manufacturers. Large factories have excellent craftsmanship and considerable output, and the cost may be controlled at a low level, and the price may be competitive; small factories may be limited by technology and scale, and the cost is higher and the price is also high.
    Second, the fluctuation of raw material prices has a significant impact. In the production of this compound, if the supply of raw materials is tight or the price rises, the price of the finished product will also rise; conversely, if the raw materials are abundant and the price falls, the price of the product may fall.
    Third, the amount of market demand is also the key. If the market demand for this product is strong, the supply is in short supply, and the price will rise; if the demand is flat, the supply is oversupplied, and the price will decline.
    Fourth, the number of transactions is different, and the price is also different. Bulk buyers, due to large quantities, merchants may give discounts, and the unit price is lower; for a small number of buyers, the unit price may be relatively high.
    Looking at the market, the price of this 5- (chloromethyl) -1,2,3-trifluorobenzene may range from tens of yuan to hundreds of yuan per gram. The specific price requires the purchaser to consult each supplier in detail, and obtain a more accurate quotation based on the current market conditions and their own procurement conditions.