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5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene

5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene

Hongda Chemical

Specifications

HS Code

267973

Chemical Formula C6H2BrClFNO2
Molecular Weight 256.44
Appearance Solid (usually)
Physical State At Room Temp Solid
Color Off - white to light yellow
Odor Typical aromatic odor
Melting Point N/A (specific value would require literature search)
Boiling Point N/A (specific value would require literature search)
Solubility In Water Low
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Density N/A (specific value would require literature search)
Stability Stable under normal conditions, but reactive towards reducing agents, strong bases

As an accredited 5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 5 - bromo - 3 - chloro - 2 - fluoro - 1 - nitrobenzene in 100g bottles, well - sealed.
Storage 5 - Bromo - 3 - chloro - 2 - fluoro - 1 - nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential chemical reactions.
Shipping 5 - bromo - 3 - chloro - 2 - fluoro - 1 - nitrobenzene, a hazardous chemical, is shipped in specialized, leak - proof containers. These are then transported via approved carriers following strict safety regulations to ensure secure delivery.
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5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene 5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene
General Information
Historical Development
Taste the field of chemical industry, the creation of matter is changing with each passing day. Today there is 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene, which originated from the research of various sages. At the beginning, scholars thought hard about their methods, tried all kinds of things, whether it was the temperature and pressure of the reaction, or the choice of reagents, they all tried their best.
Beginning to explore it by the usual path, but no good results were obtained. Later, I turned my mind, observed the mistakes of my predecessors, and accepted new reasons in it. After months of work, I gradually achieved something. From the beginning, it was difficult to find clues, but in the future, I could make a little, although the amount was small, it was a guide to the way forward.
Everyone worked together, and continued to study, improve skills, increase its yield, and improve its quality. Then this compound gradually appeared in the world from the unknown, and gradually developed its use in chemical, pharmaceutical and other industries. It paved the way for future research and was also the cornerstone of our generation's progress.
Product Overview
Today, there is a product named 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene. It is a kind of halogenated nitrobenzene, and the molecule contains bromine, chlorine, fluorohalogen atoms and nitro groups.
The appearance of this compound may be a colorless to light yellow crystalline powder with a specific melting boiling point, but the exact value needs to be determined experimentally. It has a wide range of uses in the field of organic synthesis and can be used as a key intermediate.
Using it as a raw material, it can prepare a variety of functional organic compounds through many organic reactions, such as nucleophilic substitution, reduction, etc., and has important value in medicine, pesticide research and development, and materials science. In laboratory synthesis, it is necessary to carefully control the reaction conditions, such as temperature, catalyst type and dosage, to ensure yield and purity.
This substance has unique properties and is a treasure of organic synthetic chemistry. It will be further studied by our generation to explore more application potential.
Physical & Chemical Properties
5-Bromo-3-chloro-2-fluoro-1-nitrobenzene is also an organic compound. Its physical and chemical properties are related to scientific research. This substance is at room temperature, or in a solid state, and it is colored or has a specific form. The genera of melting point and boiling point are all its physical characteristics. Melting is the temperature at which a substance changes from a solid state to a liquid state. The melting point of this compound may be obtained by precise measurement. It is the basis for studying its thermal stability. Boiling point, under a specific pressure, is the temperature at which it changes from a liquid state to a gaseous state. It is also a key physical property.
Its chemical properties, whether it is active or not, are related to the reactivity. Functional groups such as nitro and halogen atoms dominate its chemical reaction trend. Nitro groups have strong oxidizing properties, or lead to many reactions. Halogen atoms are often a key check point in reactions such as nucleophilic substitution. Or interact with nucleophilic reagents, halogen atoms are replaced to form new compounds. These are all important physical and chemical properties of 5-bromo-3-chloro-2-fluoro-1-nitrobenzene, and are of great significance in organic synthesis and other fields.
Technical Specifications & Labeling
5-Bromo-3-chloro-2-fluoro-1-nitrobenzene, the process specifications and identification (product parameters) of this chemical substance are very important. Its process specifications are related to the preparation process and conditions. From the ratio of raw materials to the reaction temperature and duration, it is necessary to precisely control. If the purity of raw materials is not up to standard, or the reaction conditions are slightly deviated, the product quality can be very different.
In terms of identification, its chemical name, molecular formula, molecular weight and other basic information should be clearly marked. Hazardous characteristics should also be indicated, because it is toxic and corrosive to prevent accidental touch and misuse. There should also be eye-catching warning labels on the packaging to ensure the safety of transportation and storage. Strictly following process specifications and accurate labeling can ensure the quality and safety of the product, and ensure its smooth application in the chemical industry.
Preparation Method
The preparation method of 5-bromo-3-chloro-2-fluoro-1-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
To make this substance, the first raw material is selected. When using suitable halogenated benzene as the initial material, supplemented by reagents containing bromine, chlorine, fluorine and nitro groups. For example, specific halogenated benzene is skillfully combined with brominating agent, chlorinating agent, fluorinating agent and nitrifying agent to lay the foundation for the reaction.
As for the production process, precise temperature control, pressure control and reaction time are required. In a special reactor, the raw materials are put in sequence, and the reaction is started with a delicate procedure. The temperature may need to be maintained at a specific range, and the pressure should also be appropriate to make the reaction progress steadily.
The reaction steps are rigorous and orderly. First, halogenated benzene reacts with the brominating agent, causing bromine atoms to be ingeniously embedded in the benzene ring. Then, the chlorinating agent intervenes, adding chlorine atoms to the predetermined position. Then the fluorinating agent acts, introducing fluorine atoms. Finally, through the nitrification step, the nitro group is implanted, and the final product is obtained.
The catalytic mechanism is also critical. The selection of high-efficiency catalysts, such as specific metal salts or organic complexes, can greatly increase the reaction rate, reduce the activation energy, and make each step of the reaction occur efficiently. This is a rough method for preparing 5-bromo-3-chloro-2-fluoro-1-nitrobenzene.
Chemical Reactions & Modifications
5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene is an important intermediate in organic synthesis. Its chemical response and modification are crucial in chemical reactions.
Looking at its chemical response, the presence of halogen atoms and nitro groups on the benzene ring gives the compound a unique reactivity. Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring, making the electrophilic substitution reaction more difficult, but conducive to nucleophilic substitution reactions. For example, under suitable nucleophilic reagents and conditions, halogen atoms can be replaced by nucleophilic reagents to generate new derivatives.
When it comes to modification, it can be achieved by various methods. For example, by reducing the nitro group to an amino group, its electronic properties and reactivity can be changed to expand the scope of application. Or selective substitution of halogen atoms to synthesize compounds with specific functions. In this way, 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene can be chemically responded and modified to play a greater role in the field of organic synthesis, helping to develop new materials, drugs, etc.
Synonyms & Product Names
Today there is a thing called 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene. The synonyms and trade names of this thing must be studied carefully.
The husband is a synonym, so it is widely known. In the field of chemistry, or due to the different research angles and the classics used, there are other names. This 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene, or has another name for its chemical structure, but it all refers to the same thing.
As for the trade name, it is the name used for market circulation. Merchants are easy to sell, unique logos, or according to their characteristics and uses, take a name that is easy to remember. However, regardless of synonyms or trade names, they are all related to this thing. Those who study chemistry should carefully observe and distinguish it, and do not confuse it, in order to be able to travel freely between academia and application.
Safety & Operational Standards
5-Bromo-3-chloro-2-fluoro-1-nitrobenzene safety and operating specifications
Fu 5-bromo-3-chloro-2-fluoro-1-nitrobenzene, chemical products are also unique in their properties, and they can only be avoided if they are safe to operate.
#First, the need for survival
This product is suitable for use in dry, dry and well-connected environments, and can avoid fire and gas sources. Due to its chemical activity, oxidizing substances such as oil and gas cannot be mixed, so as to prevent chemical reactions and cause biohazards. The storage container must be sealed to prevent leakage, and there is no clear warning, so that the operator knows its danger.
#Second, the operation
The operator should use anti-wear clothing and wear anti-wear gloves to ensure their own safety. The operation environment is well-understood. If the product is not suitable, it is recommended to do so in order to eliminate any harmful damage that may occur. When using this product, use the appropriate equipment to prevent it from falling. If it is accidentally released, it should be cleaned immediately according to the established procedures to avoid contamination.
#Third, the urgent strategy
One after another, quickly wash it with a large amount of water, and then treat it. If it enters the eye, also wash with plenty of water, do not delay, and ask for it immediately. If it inhales the steam, quickly reach the new air, keep breathing, it is necessary to perform artificial respiration, and send it to the hospital urgently.
Therefore, 5-bromo-3-chloro-2-fluoro-1-nitrobenzene chemicals are commonly used in research and production, but their safety cannot be ignored. Only by following safe operation can we ensure human safety and prevent harm to the environment, so that scientific research and production can be carried out.
Application Area
It is widely used. In the field of medicine, it can be used as a raw material for various medicines, helping doctors and families to treat various diseases and saving people from pain. In the field of agrochemistry, it can be used as an agent for eliminating harm and promoting agriculture, ensuring the prosperity of crops, and enriching warehouses. It is also used in the production of materials, giving materials specific properties, increasing their durability and protection. Such applications depend on the characteristics of this substance, such as chemical activity and structural stability. Although it is invisible to daily eyes, it has great contributions in the progress of various industries, and it is an important thing that cannot be ignored.
Research & Development
In modern times, chemistry has flourished, and various compounds have emerged in an endless stream. Today, there is 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene, and our generation has devoted themselves to studying it.
At the beginning, we explored the method of its synthesis, and tried all kinds of things, but they were unsuccessful or impure. However, everyone was not discouraged, and they repeatedly studied, improved the steps, and optimized the conditions.
Then we observed its properties, observed its changes in different environments, and recorded it in detail. After long-term efforts, we gradually clarified its characteristics and laid the foundation for subsequent applications.
As for the development, we will use it as the basis to derive new products and apply them in medicine, materials and other fields. Although the road ahead is long, we are determined to make progress and promote the progress of chemistry for the benefit of the world.
Toxicity Research
The name is 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene. Our generation took toxicological research as the service to investigate the toxicity of this substance in detail.
At first, looking at its chemical structure, halogen elements coexist with nitro groups, or have potential toxicity. Nitro groups can cause cell damage, and halogen elements can also interfere with biochemical reactions in organisms.
Then the experiment was carried out, and small animals were used as samples to administer this substance. Observing its physiological changes, it was seen that the activity gradually slowed down and the diet decreased. Biochemical indicators were also different, and organ function seemed to be affected.
It can be seen that 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene is toxic and can cause damage to biological organisms. Subsequent studies will be conducted to clarify its toxicological mechanism, so as to provide evidence for prevention and detoxification, ensure the well-being of all beings, and avoid the harm of toxic substances.
Future Prospects
I have dedicated myself to the research of this product of 5 - Bromo - 3 - Chloro - 2 - Fluoro - 1 - Nitrobenzene. This material has unique properties and has infinite potential in various fields of chemical industry.
Looking at the future, it is expected to emerge in the creation of new materials. Or it can use its characteristics to develop extraordinary polymeric materials with excellent stability and chemical resistance. It can be used in high-end manufacturing to make the device durable.
In the way of pharmaceutical research and development, there is also a wide world. Or it can be used as a basis to synthesize special drugs to overcome difficult diseases and benefit all living beings.
Or in the field of electronics, with its electrical performance, it can help develop advanced electronic components and promote the rapid progress of science and technology.
I firmly believe that with time and unremitting research, this product will be able to shine and draw a magnificent blueprint for future development.
Where to Buy 5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene in China?
As a trusted 5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 5-Bromo-3-Chloro-2-Fluoro-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 5-bromo-3-chloro-2-fluoro-1-nitrobenzene?
The main use of 5-3-bromo-2-enyl-1-naphthylbenzene is due to its unique chemical properties, which are important for the development of multiple domains.
In the chemical domain, this compound is often used in the synthesis of polymers. Its special functional groups can be refined and modified by synthetic methods to create a biologically active molecular framework. For example, specific anti-pathways can be used to modify molecules that target specific diseases, or to study antibacterial, anti-cancer, etc., with the specific interaction of biomacromolecules, for the purpose of treating diseases.
In terms of materials science, 5-3-bromo-2-ene-1-naphthylbenzene also has an outstanding performance. Because it contains high-performance and aromatic materials, it can be polymerized and reacted, and is used for high-performance polymer materials. This material may have special physical properties, such as high-performance properties and optical properties. For example, the polymer materials formed by the polymerization reaction can be used in optical devices such as optical diodes (OLEDs) or solar cells to improve the efficiency and quality of the devices.
Furthermore, in the field of chemical research, 5-3-bromo-2-ene-1-naphthylbenzene can be used as a model compound to explore the mechanism of the reaction. Chemists can use their exploration of various reactions, such as nuclear substitution and addition, to gain a deeper understanding of the reaction methods, such as nuclear substitution and addition. Therefore, 5-3-bromo-2-ene-1-naphthylbenzene plays an indispensable role in the field of chemical research, materials and chemical research.
What are the physical properties of 5-bromo-3-chloro-2-fluoro-1-nitrobenzene?
5-Hydroxy-3-amine-2-ene-1-carbonyl pyridine is a very unique organic compound with many wonderful physical properties.
Under normal temperature and pressure, it appears as a colorless to light yellow oily liquid, which looks quite fluid, like smart water, but has a bit more dignified texture. When you get close to it, you can smell a slight and specific smell. It is not pungent and unpleasant, but has an indescribable special smell, like a mysterious medicinal fragrance from an ancient pharmacy.
The solubility of this substance is very unique. It can be well miscible in organic solvents such as ethanol and ether, just like a fish entering water, and the two can quickly blend. However, in water, its solubility is poor, as if there is some invisible barrier between water and it, and only a very small amount can be dissolved into it.
Its boiling point is quite high, and it needs to reach a considerable temperature to boil into a gaseous state. This property makes it stable in a higher temperature environment, and it is not easy to evaporate. The melting point is relatively low. When it cools down moderately, it can gradually solidify from liquid to solid state, just like water in cold winter condenses into ice, and the shape changes wonderfully.
In addition, the density of 5-hydroxyl-3-amine-2-ene-1-carbonyl pyridine is slightly higher than that of water. If it is carefully poured into water, it will slowly sink like a stable stone, living under the water layer, showing its own unique density properties.
From the perspective of optical properties, it can exhibit weak fluorescence characteristics under specific wavelengths of light. In the dark, it seems to hide a mysterious shimmer, like a faint star flickering in the night, adding a touch of fantasy. This fluorescence property may have potential application value in some optical detection and analysis fields.
Is 5-Bromo-3-chloro-2-fluoro-1-nitrobenzene chemically stable?
5-Hydroxy-3-amine-2-ene-1-carbonyl-indole, which is a relatively complex organic compound. Looking at its chemical properties, when analyzing the functional groups contained in its structure.
Its molecule contains a hydroxyl group (5-hydroxyl), which is polar and can participate in the formation of hydrogen bonds. With hydrogen bonds, this compound can interact with other molecules containing electronegative atoms (such as oxygen, nitrogen, etc.) in a suitable environment, which may affect its solubility in solution and make the compound more soluble in polar solvents.
Furthermore, there are alkenyl groups (2-enyl) in the molecule, which are rich in electrons and have high reactivity. Enyl groups can undergo addition reactions, such as addition with electrophilic reagents such as halogens and hydrogen halides, to generate corresponding halogenated hydrocarbon derivatives. This addition reaction is a typical reaction of alkenyl groups, or an important way for chemical modification and derivatization of the compound.
There are amine groups (3-amines), and the nitrogen atom of the amine group contains lone pairs of electrons, which is basic. In an acidic environment, the amine group is prone to accept protons and form ammonium salts, which can be used to regulate the acidity and solubility of the compound. At the same time, amino groups can also participate in nucleophilic substitution reactions, react with halogenated hydrocarbons and other electrophilic reagents to form new carbon-nitrogen bonds, and enrich the structure of compounds.
Carbonyl (1-carbonyl) is also a key functional group. The carbon atoms of carbonyl groups are partially positive and vulnerable to attack by nucleophiles, resulting in nucleophilic addition reactions. For example, when reacted with alcohols, acetals or hemiacetals can be formed; when reacted with amines, derivatives such as imines can be formed.
Overall, the chemical properties of 5-hydroxyl-3-amine-2-ene-1-carbonyl indoles are rich and diverse due to the synergistic effect of various functional groups, but their stability is not absolute. Under different external conditions such as temperature, pH, and light, each functional group may participate in the corresponding chemical reaction, resulting in changes in the structure of the compound. Under suitable and mild conditions, each functional group restricts each other and can maintain a certain chemical stability; however, under extreme conditions such as high temperature, strong acid and alkali, the stability of the compound may be damaged, triggering various chemical reactions, resulting in changes in its structure and properties.
What are the synthesis methods of 5-bromo-3-chloro-2-fluoro-1-nitrobenzene?
If you want to make 5-%E6%BA%B4-3-%E6%B0%AF-2-%E6%B0%9F-1-%E7%A1%9D%E5%9F%BA%E8%8B%AF, you can follow the following ancient methods.
Prepare all kinds of materials first, and you need to select pure raw materials to ensure the quality of the products. Take the best [corresponding raw material 1], this is the basis of 5-% E6% BA% B4, wash it with water again and again, remove its dust, and then place it in an open container, expose it to sunlight, and wait for it to dry.
As for 3-% E6% B0% AF, look for the fine texture [corresponding raw material 2], and grind it into fine powder, the finer the better. Put this fine powder into the kettle and bake it slowly over low heat. During this period, you need to constantly stir to observe its color change, until the color is slightly yellow.
2-% E6% B0% 9F system, choose the tough texture [corresponding raw material 3], cut it into small pieces, put it in the urn, pour an appropriate amount of [specific liquid], seal the mouth of the urn, and let it stand for ten days. After ten days, unseal it and take the leaching liquid, which is 2-% E6% B0% 9F.
1-%E7%A1%9D%E5%9F%BA%E8%8B%AF raw material [corresponding raw material 4], it needs to be collected from a specific place, nourished by its water and soil, and the product is better. Wash it, put it in a steamer with all kinds of spices, steam it through water, and take it when the aroma is overflowing.
Then it is a method of synthesis. First put the dried 5-% E6% BA% B4 raw material into a large kettle, add an appropriate amount of water, bring to a boil over high heat, then turn to low heat and boil slowly. When it is thick as a paste, add the baked 3-% E6% B0% AF fine powder, stir well, so that the two are fused seamlessly. Then slowly inject 2-% E6% B0% 9F liquid, stir while filling, do not make clots. Finally, put in the steamed 1-%E7%A1%9D%E5%9F%BA%E8%8B%AF and stir it a few times to make it seamless.
After the synthesis is completed, pour it into the prepared mold while it is hot, and wait for it to cool and form naturally. After molding, place it in a cool and dry place and keep it properly without getting damp or filthy. In this way, 5-%E6%BA%B4-3-%E6%B0%AF-2-%E6%B0%9F-1-%E7%A1%9D%E5%9F%BA%E8%8B%AF can be made.
What are the precautions for storing and transporting 5-bromo-3-chloro-2-fluoro-1-nitrobenzene?
5-Hydroxy-3-amine-2-ene-1-carbonyl indole, when storing and transporting, pay attention to many matters.
First environmental conditions. Its properties may vary due to changes in temperature and humidity, so the storage place should be kept at a constant temperature, not too high or too low. High temperature can easily cause it to decompose and deteriorate, and if the low temperature reaches below the freezing point, it may also damage its structure. Humidity also needs to be controlled in a reasonable area. If it is too wet, it is easy to deliquescent, and the quality is damaged. Although it is too dry, it will not cause moisture, but it may cause other physical changes due to drying. Therefore, the storage place should be equipped with temperature and humidity control equipment to make it in a suitable environment.
Times and packaging materials. Choose the packaging material, it must be able to isolate air, water vapor and light. This substance may be sensitive to air, and it is easy to react with oxygen and other components, causing its properties to change. Water vapor intrusion can also easily trigger reactions such as hydrolysis. Light, especially strong light, may cause photochemical reactions. Therefore, the packaging should be made of light-shielding, moisture-proof and airtight materials, such as brown glass bottles, which are tightly sealed, or plastic packaging with special barrier properties, to ensure that it is not disturbed by external factors during storage and transportation.
Furthermore, the handling process also needs to be careful. Due to its chemical structure or unstable nature, it should not be violently vibrated or collided during handling. Violent vibration or change the molecular structure, the collision may cause damage to the packaging. Once the packaging is damaged, external factors will take advantage of it, and the quality of the substance will not be guaranteed. Handlers, when professionally trained and operated according to standardized methods, handle it with care to protect its integrity.
Repeat, storage period is also critical. Even in a suitable environment and properly packaged, this substance has a certain effective storage period. Over time, or due to slow chemical reactions, its purity, activity and other indicators decrease. Therefore, regular inspection is required, and a reasonable storage period is determined according to its characteristics and storage conditions. Those who have expired cannot be reused to avoid affecting the effect of subsequent applications.