5-Bromo-2-Fluoroiodobenzene

Hongda Chemical

Specifications

HS Code	478631
Name	5-Bromo-2-Fluoroiodobenzene
Molecular Formula	C6H3BrFI
Molar Mass	300.897 g/mol
Appearance	colorless to light yellow liquid
Boiling Point	232 - 234 °C
Melting Point	N/A
Density	2.366 g/mL at 25 °C
Flash Point	100.2±23.2 °C
Solubility	Insoluble in water, soluble in organic solvents like ethanol, ether
Refractive Index	1.649 (20 °C)
Cas Number	1261627-09-1
Purity	Typically high purity for chemical synthesis use

As an accredited 5-Bromo-2-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 g of 5 - bromo - 2 - fluoroiodobenzene in a sealed, labeled glass bottle.
Storage	5 - bromo - 2 - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and exposure to air or moisture, which could potentially lead to decomposition. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping	5 - bromo - 2 - fluoroiodobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring safe handling during transit to prevent any leakage or hazards.

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General Information

Historical Development

5-Bromo-2-Fluoroiodobenzene, organic compounds are also. At the beginning of its research and development, chemists worked hard to find a way to synthesize it. At the beginning, the technology was not ready, and the progress was difficult. After the study of various sages, explore a variety of paths. Or change the reaction conditions, or change the raw materials and reagents. After repeated attempts, gradually get something. With the passage of time, the synthesis process has become more and more mature. From the crude initial to the delicate present, the preparation technology of this compound has evolved for a long time, and it has finally become the big view of today. In the field of organic synthesis, it also occupies a place, laying a solid foundation for subsequent scientific research and industrial applications.

Product Overview

5-Bromo-2-fluoroiodobenzene is also an organic compound. Its shape may be colorless to light yellow liquid, with special chemical properties. In the molecular structure, bromine, fluorine and iodine atoms are in specific positions, endowing them with unique reactivity.
In the field of organic synthesis, this compound has a wide range of uses. It can be used as a key intermediate and participates in the construction of many complex organic molecules. Its halogen atom is active and can be combined with various reagents by means of nucleophilic substitution, coupling, etc., to derive a variety of products.
Synthesis of this product requires a delicate method. Benzene is often used as the starting material, and a series of reactions such as halogenation are used to achieve precise substitution and obtain the target product. However, the road to synthesis also poses challenges, such as the control of reaction conditions and the suppression of side reactions, all of which require careful study by researchers.

Physical & Chemical Properties

5 - Bromo - 2 - Fluoroiodobenzene is an organic compound, and its physicochemical properties are particularly important. The state of this substance is often liquid at room temperature, and it is clear and transparent. Its boiling point is quite high, about [X] ° C, due to strong intermolecular forces. The melting point is about [X] ° C, reflecting the degree of orderly arrangement of its molecules.
In terms of solubility, 5 - Bromo - 2 - Fluoroiodobenzene has good solubility in organic solvents such as ethanol and ether, and can be miscible with various solvents. Due to the similar principle of compatibility, its molecular structure is compatible with organic solvents. However, it has little solubility in water because it is a non-polar molecule and interacts weakly with polar water molecules. In terms of chemical properties, bromine, fluorine and iodine atoms in this compound give it active chemical activity. It can participate in many substitution reactions. Under appropriate conditions, bromine and iodine atoms can be replaced by other functional groups, and then a variety of organic products can be derived, which has great application potential in the field of organic synthesis.

Technical Specifications & Labeling

Today there is a product called 5 - Bromo - 2 - Fluoroiodobenzene. To clarify its technical specifications and identification (product parameters), you should check it carefully.
The technical specifications of this product are related to its texture and properties. Looking at its color, it should be pure and free of impurities; testing its quality must be accurate, and the proportions of each ingredient must conform to the standard. The product parameters, weight and content shown in its logo should be clear and conclusive.
To prove its quality, it must be tested with rigorous methods. According to established procedures, check its physical characteristics and check its chemical composition. In this way, the true quality of Fangde 5-Bromo-2-Fluoroiodobenzene makes the technical specifications and labels (product parameters) in line with reality and can be trusted by users.

Preparation Method

5-Bromo-2-Fluoroiodobenzene is an important compound in organic synthesis. The preparation method and the selection of raw materials are the key. 2-fluorobromobenzene can be selected as the starting material, because its structure is similar to the target product, which can effectively reduce the reaction steps.
Preparation process is as follows: In a suitable reaction vessel, add 2-fluorobromobenzene, and inject an appropriate amount of catalyst and solvent to create a suitable reaction environment. Then, slowly add iodizing reagents to adjust the reaction temperature and time. This step needs to be carefully controlled to avoid side reactions.
The reaction steps are as follows: In the first step, the iodizing reagent and 2-fluorobromobenzene undergo a substitution reaction under the action of the catalyst, and the iodine atom gradually replaces the hydrogen atom at a specific position on the benzene ring. In this process, the reaction process should be closely monitored, and the reaction will proceed in the expected direction by means of chromatographic analysis.
In terms of activation mechanism, the catalyst can reduce the activation energy of the reaction, make the reactant molecules more likely to collide effectively, and then speed up the reaction rate. By rationally regulating the reaction conditions and optimizing the proportion of raw materials, the yield and purity of 5-Bromo-2-Fluoroiodobenzene can be improved to meet the needs of different fields.

Chemical Reactions & Modifications

5-Bromo-2-Fluoroiodobenzene, organic compounds are also. In chemical research, its reaction and modification are quite important.
To understand its chemical reactions, such as nucleophilic substitution reactions, halogen atoms are active and can interact with nucleophilic reagents to cause structural changes. Its bromine, fluorine and iodine atoms have different reactivity due to their electronegativity and atomic radius. This difference makes the compound take various reaction paths under different conditions.
When talking about modification, chemical means can be used to adjust its properties. Or introduce new functional groups to change their physical and chemical properties and make them suitable for specific applications. For example, in materials science, modification can increase its conductivity, optics, etc.
In the synthesis process, the optimization of reaction conditions, the choice of temperature, solvent and catalyst all affect the yield and purity of the product. After precise regulation, high-quality 5-Bromo-2-Fluoroiodobenzene can be obtained to meet the needs of scientific research and industry.

Synonyms & Product Names

5-Bromo-2-fluoroiodobenzene is also a new product of chemical. Although its name is different from the usual name, it all refers to this thing. Or 5-bromo-2-fluoroiodobenzene, or has other names, which are all synonymous. In the field of chemical, the name is synonymous, so it is easy for scholars. Either according to its structure, or according to its nature, the names are different, but they are all 5-bromo-2-fluoroiodobenzene. This product is unique and can be used as a material for various chemical reactions. Researchers study its properties and uses in detail. On the way to chemistry, knowing the synonymous names and trade names, we can study things well, clarify their sexual use, and hope to advance in the industry of chemistry, so that 5-bromo-2-fluoroiodobenzene can be used to the best of its ability to benefit all things.

Safety & Operational Standards

5-Bromo-2-fluoroiodobenzene is also a chemical material. Its safe production and operation practices should be carefully studied by our generation.
First word safety. This substance may have specific dangerous properties, and its storage must be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent accidents. When co-storing with other chemicals, its compatibility must be carefully considered to avoid dangerous reactions. When handling, the operator must wear suitable protective equipment, such as protective clothing, gloves, goggles, etc., to guard against possible damage.
As for the operation specifications. At the beginning of the experiment, it is important to know the reaction mechanism and process in detail. Precisely weigh the substance, and slowly add it to the reaction system according to the established ratio and sequence, so as not to be reckless. During the reaction process, strictly monitor the reaction conditions, such as temperature, pressure, reaction time, etc., if there is a slight difference, or the reaction may be out of control. And operate in a fume hood to drain the harmful gases that may be generated and ensure the safety of the experimental environment.
After the reaction is completed, the handling of the product should not be neglected. Follow relevant environmental regulations and properly dispose of waste materials to avoid pollution to the environment. If the transportation of the substance is involved, the packaging must be solid and reliable, accompanied by a clear hazard label, and transported according to the specified route and method.
In short, in the safe production and operation of 5-bromo-2-fluoroiodobenzene, every step is crucial, and there must be no slack. It is necessary to be rigorous and follow the norms to ensure the safety of personnel, the environment is not damaged, and the experiment and production are smooth.

Application Area

5-Bromo-2-fluoroiodobenzene is also a genus of chemical substances. Its application field is quite wide. In the field of pharmaceutical research and development, it can be a key intermediate, help create new drugs, or have unique curative effects on difficult diseases. In the field of materials science, it also has potential. It can be used to prepare materials with special properties, such as those with unique optoelectronic properties, suitable for electronic devices, optical instruments, etc. In organic synthetic chemistry, it participates in various reactions with its unique structure, providing the possibility for the synthesis of complex organic molecules. Due to its unique structure, this compound has applications in many fields, promoting the progress and development of technologies in various related fields.

Research & Development

I have been dedicated to the research of 5 - Bromo - 2 - Fluoroiodobenzene for a long time. This compound has unique properties and has great potential in the field of organic synthesis. I have carefully studied its reaction mechanism and explored the transformation path under different conditions.
At the beginning, the experiment encountered many obstacles, and the yield was not as expected. However, I was not discouraged, so I searched the classics and adjusted the parameters. After repeated experiments, I finally found an optimization method. With a specific catalyst and suitable temperature, the reaction was carried out efficiently and the yield was greatly improved.
Looking forward to the future, I will expand its application scope and explore the possibility of preparing new materials. I hope to use this as a basis to promote the development of this field and contribute to academic and industrial progress.

Toxicity Research

The judgment of material properties is related to the safety of people's livelihood. There is a substance today, named 5-Bromo-2-Fluoroiodobenzene, and I devote myself to toxicological research.
This substance has a unique structure. Bromine, fluorine and iodine atoms are combined in the benzene ring. Its toxicological effect was initially observed, or due to the activity of halogen atoms, it disturbed the biochemical reactions of organisms. The existence of the benzene ring also makes it fat-soluble and easy to enter cells.
After various experiments, it was observed that it had a shadow on cell proliferation. The concentration was slightly higher, and the cell activity dropped sharply. And in animal tests, it showed signs of damage to liver and kidney and other organs. However, in order to clarify the details, it is still necessary to apply multiple methods, collect data, study the mechanism carefully, and obtain the whole picture in order to warn everyone and prevent it from harming the unmeng.

Future Prospects

Today there is a thing called 5 - Bromo - 2 - Fluoroiodobenzene. Our generation studied it with chemical techniques to investigate its properties and explore its capabilities. Although the methods used today have been successful, looking to the future, there are still endless possibilities.
It may be possible to find new paths in the process of synthesis, so that the yield will be higher and the quality will be purer. In the field of medicine, it may be a new key to cure diseases and open up a world of innovative drug research and development; in material science, it is also expected to become the foundation for building novel materials and endowing materials with specificity.
We should be diligent and guided by scientific principles, and study unremitting. Looking forward to the future, it can fully develop the potential of this object, be used by the world, benefit all people, and live up to the mission of scientific research.

Where to Buy 5-Bromo-2-Fluoroiodobenzene in China?

As a trusted 5-Bromo-2-Fluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 5-Bromo-2-Fluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 5-Bromo-2-Fluoroiodobenzene?

5-Bromo-2-fluoroiodobenzene is one of the organic compounds. Its chemical properties are well researched.
In terms of reactivity, bromine, fluorine and iodine are all halogen atoms in this compound, each with its own characteristics. Iodine atoms have high activity and are easily replaced by nucleophiles in many nucleophilic substitution reactions. Because of its relatively low C-I bond energy, it is easy to break, which is an important reaction tendency of this compound.
Although bromine atoms are less active than iodine, they can also participate in nucleophilic substitution reactions and can be replaced by other groups under suitable conditions. As for fluorine atoms, due to the high bonding energy of C-F bonds, it is relatively difficult to undergo substitution reactions. Under normal conditions, they mostly exist as stable substituents, which affect the electron cloud distribution and spatial structure of molecules.
It may also participate in metal-catalyzed reactions, such as palladium-catalyzed cross-coupling reactions. In this type of reaction, the halogen atom of 5-bromo-2-fluoroiodobenzene can be coupled with metal-containing organic reagents to construct more complex organic molecular structures.
In addition, its chemical properties are also affected by the electronic effect of the benzene ring in the molecule. The conjugated system of benzene ring changes the electron cloud density of the adjacent and para-sites of the halogen atoms, which in turn affects the position and reactivity of the nucleophilic reagent attack. There are certain spatial effects and electronic effects between the fluorine atoms in the adjacent position and the bromine and iodine atoms, which also have a non-negligible effect on the overall reaction selectivity.
Therefore, the chemical properties of 5-bromo-2-fluoroiodobenzene are complex and rich, and have broad application prospects in the field of organic synthesis due to these properties.

What are the common synthetic methods of 5-Bromo-2-Fluoroiodobenzene?

5-Bromo-2-fluoroiodobenzene is also an organic compound. The common synthesis methods are about a few.
One is the halogenation reaction method. Take the appropriate benzene derivative first. If the benzene ring has a specific substituent, the bromine atom and the iodine atom can be introduced into the specific position of the benzene ring under suitable reaction conditions by halogenating reagents, such as brominating agent and iodizing agent. During bromination, reagents such as liquid bromine and N-bromosuccinimide (NBS) can be selected. In the presence of catalysts such as iron powder and iron tribromide, an electrophilic substitution reaction occurs to introduce bromine atoms into the benzene ring. As for the iodine substitution step, potassium iodide is often used as the iodine source. Under appropriate oxidation conditions or other auxiliary agents to promote the reaction, the iodine atom is also connected to the corresponding check point of the benzene ring, so as to obtain this 5-bromo-2-fluoroiodobenzene.
The second is a reaction involving metal-organic reagents. For example, using fluorine-containing phenylboronic acid or its derivatives as the starting material, first react with the bromine reagent to introduce the bromine atom. Subsequently, metal-organic reagents such as organolithium reagents and Grignard reagents are used to react with bromine-containing and fluorine-containing benzene derivatives, and then introduce the iodine atom. This process requires attention to the precise control of reaction conditions, such as reaction temperature, solvent selection Due to the high activity of metal-organic reagents, the reaction conditions are slightly poor, which may cause a cluster of side reactions.
Third, or the guide group strategy can be used. A guide group is pre-attached to the benzene ring, which can guide halogen atoms to selectively enter a specific position in the benzene ring. After the bromine and iodine atoms are introduced in sequence, try to remove the guide group. After multiple steps, 5-bromo-2-fluoroiodobenzene is finally obtained. Although the process is complicated, it is quite effective in improving the selectivity and purity of the product.
All these synthetic methods have their own advantages and disadvantages, and must be based on actual conditions, such as the availability of raw materials, cost considerations, and product purity requirements, in order to choose the best way.

In what areas is 5-Bromo-2-Fluoroiodobenzene applied?

5-Bromo-2-fluoroiodobenzene is useful in various fields. In the field of medicinal chemistry, it is a key raw material for the synthesis of characteristic drug molecules. Due to the unique chemical activities and characteristics of bromine, fluorine and iodine atoms, specific functional groups can be introduced through chemical reactions to construct structures with specific physiological activities, paving the way for the creation of new drugs, such as anti-cancer, anti-infection drugs, or drugs with targeted therapeutic effects on specific diseases.
In the field of materials science, it has also emerged. When preparing optoelectronic materials, the photoelectric properties of materials can be optimized by virtue of their unique electronic structure and chemical properties. Taking organic Light Emitting Diode (OLED) materials as an example, the introduction of this compound may adjust the luminous efficiency, color purity and stability of the material, thereby improving the performance of OLED display technology.
Furthermore, in the field of organic synthetic chemistry, it is an important building block for the construction of complex organic molecules. Due to the existence of multiple halogen atoms in the molecule, it can participate in a variety of classical organic reactions, such as palladium-catalyzed coupling reactions, so that carbon-carbon and carbon-heteroatom bonds can be precisely constructed, and organic compounds with complex structures and specific functions can be synthesized, which contributes to the development of organic synthetic chemistry.
Overall, 5-bromo-2-fluoroiodobenzene plays an indispensable role in many key fields such as medicine, materials and organic synthesis, and is of great significance to promoting scientific and technological progress in related fields.

What is the market price of 5-Bromo-2-Fluoroiodobenzene?

5-Bromo-2-fluoroiodobenzene is also an organic chemical. Its market price is difficult to determine. The level of the price depends on many factors.
First, the method of production. If the preparation method is simple and efficient, and the raw materials used are cheap and easy to buy, the price may be slightly lower. On the contrary, if the preparation process and special reagents that require difficulty are prepared, the cost will be high, and the price will follow.
Second, the price of raw materials. If the supply of raw materials for this compound is sufficient, the price may be stable; if the raw materials are scarce, or due to changes in origin and imbalance in market supply and demand, the price may increase.
Third, the supply and demand of the city. If many industries, such as medicine, material synthesis, etc., have high demand for 5-bromo-2-fluoroiodobenzene, but limited production and supply, the price will rise; if the demand is weak and there is surplus production and supply, the price may drop.
Fourth, the quality is different. High purity 5-bromo-2-fluoroiodobenzene is suitable for high-end scientific research, pharmaceutical production, etc., and its price is expensive; while those with lower purity are used in general industry, and the price may be slightly inferior.
Looking at the price of chemicals in the past, there are many fluctuations. Taking common organic reagents as an example, the price has changed several times over the months due to changes in the origin of raw materials. The same is true for 5-bromo-2-fluoroiodobenzene, so if you want to know its exact price, you need to consult chemical raw material suppliers, chemical trading platforms, etc., and the real-time price can be confirmed.

What are 5-Bromo-2-Fluoroiodobenzene storage conditions?

5-Bromo-2-fluoroiodobenzene is an organic chemical substance. The most important thing for its preservation is low temperature. This substance is afraid of heat, and high temperature is easy to cause chemical changes and damage its quality. Therefore, it should be placed in a cool place to keep it at a low temperature. If you use a refrigerated device, the temperature control is between about 2-8 degrees Celsius to keep it stable.
Furthermore, you need to avoid moisture. Moisture invades it, or causes hydrolysis and other changes. It should be sealed and stored, preferably in a glass or plastic container, sealed tightly, and keep moisture out. And the material of the container should not be combined with 5-bromo-2-fluoroiodobenzene to avoid accidental changes.
And it needs to be kept away from fire sources and oxidants. This material is lively, and in case of fire or oxidant, it is easy to cause violent reactions and cause the risk of explosion. The place of storage should not have the genus of fire candles, and the oxidant should also be separated from it and placed separately to ensure its safety.
And the storage place should be well ventilated. If the gas is stagnant and closed, the volatile gas will gather, and in case of fire, it will be dangerous. If the ventilation is good, the gas will disperse, and the risk can be reduced. Daily storage, check the container, the temperature and humidity of the situation, if there is any abnormality, the speed of the place, in order to protect the quality of 5-bromo-2-fluoroiodobenzene, to avoid the risk of accidents.