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5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene

5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene

Hongda Chemical

    Specifications

    HS Code

    567854

    Chemical Formula C7H4Br3F2
    Molar Mass 362.819 g/mol
    Appearance Typically a colorless to pale yellow liquid (assumed based on similar bromo - fluoro aromatic compounds)
    Solubility In Water Low solubility in water, as it is an aromatic organic compound with non - polar groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, and ethyl acetate
    Purity Varies depending on the manufacturing process, typically sold as high - purity (>95% in some cases) laboratory - grade product

    As an accredited 5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 5 - bromo - 2-(bromomethyl)-1,3 - difluorobenzene in sealed chemical - grade vial.
    Storage Store 5 - bromo - 2 - (bromomethyl)-1,3 - difluorobenzene in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Due to its reactivity and potential hazards, store it separately from oxidizing agents, reducing agents, and other incompatible substances.
    Shipping 5 - bromo - 2 - (bromomethyl)-1,3 - difluorobenzene is shipped in specialized, airtight containers. They are carefully packed to prevent leaks, with proper labeling indicating the chemical's nature, following strict hazardous material shipping regulations.
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    5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene 5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene
    General Information
    Historical Development
    5-Bromo-2- (bromomethyl) -1,3-difluorobenzene is also a new product of chemistry. In the past, the researchers did not see it, the technology was not caught, and they wanted to make it but could not.
    The technology is gradually emerging, and all kinds of methods are developed, so we have to study this product. At the beginning, it was difficult to make, and the production was small and expensive. However, the researchers are determined and unremitting exploration.
    After that, there was a new method, which was better than the old, the raw materials were easy to obtain, and the process was simple and efficient. The amount produced is abundant day by day, and the use is also becoming more and more widespread. In the fields of medicine, materials, etc., it
    From this perspective, this product has been unknown to the world, due to the diligence of researchers, the advancement of science and technology, and the prosperity of the chemical industry.
    Product Overview
    Today, there is a product named 5 - Bromo - 2 - (Bromomethyl) - 1,3 - Difluorobenzene. This is a chemical product with unique characteristics. Its shape is either a colorless liquid or a crystalline body, and its pure state can be seen from the perspective.
    The structure of this product is exquisite, bromine is connected to the difluorophenyl ring, and bromomethyl is attached to it, and the atoms are arranged in an orderly manner, forming this unique molecule. In the reaction, because of the activity of bromine and bromomethyl, it can often lead to many chemical changes, and can respond with a variety of reagents. It is an important raw material for organic synthesis.
    It has a wide range of uses. It is often a key intermediate in the synthesis of medicine and helps in the construction of medicinal ingredients. In the field of material science, it can also contribute to the research and development of new materials. Although its nature is lively, if you follow the scientific method, you will be able to make good use of it and add luster to the chemical industry.
    Physical & Chemical Properties
    5 - Bromo - 2 - (Bromomethyl) -1,3 - Difluorobenzene is an organic compound. Its physical properties are mostly solid at room temperature, with specific melting points and boiling points, which can be accurately measured by melting point meters and boiling point measuring devices. Its appearance may be white to light yellow powder or crystalline, which can be preliminarily determined by the naked eye.
    In terms of chemical properties, this compound has considerable reactivity due to the presence of active groups such as bromine and bromomethyl. Bromine atoms are prone to nucleophilic substitution reactions, and can interact with many nucleophilic reagents such as alcohols and amines to derive different new compounds. Methyl bromide is also active and can participate in alkylation reactions. It is widely used in the field of organic synthesis. It can be used as a key intermediate to assist in the synthesis of complex organic molecules and promote the development of organic chemistry research.
    Technical Specifications & Labeling
    There are 5-bromo-2- (bromomethyl) -1,3-difluorobenzene today, and its process specifications and identification (product parameters) are the key. Regarding its process specifications, it is necessary to study the synthesis method in detail. From the selection of raw materials, when seeking purity and no impurities, the ratio must be accurate. The reaction conditions such as temperature, pressure, and duration must be carefully controlled. A slight mistake will affect the quality of the product. As for the label, the name of the product should be clear and correct, indicating the chemical structure to prevent confusion. Parameters such as its purity and impurity content should also be clear. Only in this way can we ensure that 5-bromo-2- (bromomethyl) -1,3-difluorobenzene will play a good role in subsequent applications and live up to expectations.
    Preparation Method
    To prepare 5-bromo-2- (bromomethyl) -1,3-difluorobenzene, the method is as follows: Prepare the raw materials first, select the appropriate starting reactants, such as fluorine-containing and bromine-containing benzene derivatives. In the reaction kettle, control the temperature and pressure with precision, and interact with the raw materials according to specific reaction steps. First, the benzene ring is introduced into the bromomethyl group in a certain reaction, and then the bromomethyl group is added at a specific position through subtle steps. The reaction process requires strict adherence to operating specifications and close monitoring of the reaction process to prevent side reactions. After the reaction is completed, the pure 5-bromo-2- (bromomethyl) -1,3-difluorobenzene product is obtained by subtle separation and purification methods. Throughout the preparation process, the selection of raw materials and the control of the reaction process are crucial, and the purity and yield of the product need to be carefully controlled.
    Chemical Reactions & Modifications
    Today, there are 5-bromo-2- (bromomethyl) -1,3-difluorobenzene, which is crucial for chemical reactions and modifications.
    Looking at its reaction, it is combined with various reagents, and often changes in a specific way. Can meet nucleophilic reagents, halogen atoms are easily replaced to obtain new derivatives. At its bromomethyl group, it is very active and can lead to various reactions, such as alkylation.
    As for modification, it can be changed according to demand. Or adjust its electron cloud density to change its activity; or increase its functional groups and expand its uses. By chemical methods, turn the ordinary into magic, and change the single into complicated. This compound can be used in various fields such as medicine and materials to develop its capabilities, produce extraordinary effects, and contribute to the advancement of science and technology and the goodness of life.
    Synonyms & Product Names
    5 - Bromo - 2 - (Bromomethyl) -1,3 - Difluorobenzene, its synonymous name, in the field of my chemistry, also has another name.
    The name of Guanfu Chemistry, the name of the substance, either according to its structure or according to its nature. This compound has a bromine atom at the 5th position, a bromomethyl at the 2nd position, and a fluorine atom at the 1st and 3rd positions. Those who are synonymous, or called from the detailed analysis of the structure, such as the name of the position and the order of the group, can also be expressed differently. The name of the product may vary slightly due to the habits of the merchant and the needs of the market. Although the name is different but the quality is the same, they all refer to this specific chemical. For our chemical researchers, familiar with its synonymous name and the name of the commodity, we can be handy in experimentation and production, without confusion, and move forward smoothly to explore the mysteries of chemistry and use its nature for the benefit of the world.
    Safety & Operational Standards
    5-Bromo-2- (bromomethyl) -1,3-difluorobenzene
    F 5-bromo-2- (bromomethyl) -1,3-difluorobenzene is a special chemical product. When using and handling, it is necessary to strictly observe safety and operating practices to ensure safety.
    In terms of safety, this substance is dangerous. It may cause irritation to human skin, eyes and respiratory tract. Therefore, protective measures are essential when exposed. Operators should wear protective clothing, such as special laboratory clothes, to prevent it from coming into contact with the skin. Hands must wear protective gloves, and the material must be able to effectively resist the erosion of the substance. Eye protection should not be underestimated. Protective glasses or masks should be worn at any time to prevent accidental splashing into the eyes and causing irreparable damage.
    Operating specifications are also extremely critical. Operate in a well-ventilated environment, this is the first criterion. The use of a fume hood can remove volatile gases in time, reduce the concentration of the substance in the air, and reduce the risk of poisoning. When taking it, the action should be precise and careful to avoid spilling. The weighing process requires accurate equipment, and the amount should be strictly measured according to the experimental requirements. It must not be increased or decreased at will.
    For storage, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. The storage container must be well sealed to prevent leakage. If a leak unfortunately occurs, do not panic. In the event of a small leak, quickly absorb it with inert materials such as sand and vermiculite, and properly dispose of it after collection. Large leaks require immediate evacuation of personnel, sealing off the scene, and waiting for professional personnel to deal with it.
    In short, the operation of 5-bromo-2- (bromomethyl) -1,3-difluorobenzene must be based on safety and strict compliance with operating specifications in order to avoid disasters, ensure the smooth operation of the experiment, and protect the health of personnel.
    Application Area
    5-Bromo-2- (bromomethyl) -1,3-difluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediate for the synthesis of specific drugs. With its unique chemical structure, it can participate in various reactions and help create drugs with specific curative effects to treat various diseases.
    In the field of materials science, it also has important uses. It can be introduced into polymer materials through a specific reaction path, giving the material unique properties, such as improving its stability, weather resistance, etc., so that the material can also play an excellent role in many special environments. This compound is also an indispensable raw material in the field of fine chemicals. Through ingenious synthesis steps, it can generate many high-value-added fine chemicals to serve the needs of different industries.
    Research & Development
    In recent years, I have focused on the research of 5 - Bromo - 2 - (Bromomethyl) - 1,3 - Difluorobenzene. At the beginning, it was difficult to obtain a pure sample. The choice of raw materials and the precision of the ratio need to be considered repeatedly.
    However, I have worked tirelessly to improve the process. In the reaction conditions, the temperature and pressure are strictly controlled to make the reaction more stable. The screening of solvents has also been tried many times, and the yield has been improved.
    Viewing its application, it has great potential in the field of pharmaceutical synthesis. It can be used as a key intermediate to lay the foundation for innovative drug research and development. Although the current results are still modest, I firmly believe that with time and continued exploration, this product will be able to shine in the field of industrial production and scientific research, and promote the progress and development of related industries.
    Toxicity Research
    The toxicity of 5 - Bromo - 2 - (Bromomethyl) - 1,3 - Difluorobenzene. This substance is related to chemical research, and toxicity investigation is extremely important.
    To observe the structure of this substance, the halogen atomic site is the key. The characteristics of bromine and fluorine atoms may cause them to have special reactivity and toxic tendencies. In vivo, or interact with key biological macromolecules such as proteins and nucleic acids.
    Experiments have shown that if the organism touches this product on the surface, it may show signs of local irritation, such as redness, swelling, and ulceration. If it enters the body through breathing, it may damage the respiratory tract, causing cough, asthma, and even life-threatening. Oral ingestion may harm the digestive system, with vomiting and diarrhea.
    Therefore, the toxicity study of 5-Bromo-2- (Bromomethyl) -1,3-Difluorobenzene can provide an important basis for chemical production safety and environmental ecological protection.
    Future Prospects
    5-Bromo-2- (bromomethyl) -1,3-difluorobenzene, this is the chemical substance I have dedicated myself to studying. In the current research process, although some results have been achieved, its future development prospects are still considerable.
    This substance has a unique structure and unique properties. In the field of organic synthesis, it may show extraordinary effects. I expect that in the future, with the continuous improvement of science and technology, the exploration of its characteristics will be more in-depth.
    It is expected to emerge in the research and development of new materials, and with its special chemical structure, it will give novel properties to materials. It may be able to play a big role in the field of medical chemistry and help develop drugs with better curative effects and fewer side effects. I firmly believe that with unremitting research, this substance will be able to bloom brightly in the future, adding a strong touch to the development of the chemical field.
    Where to Buy 5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene in China?
    As a trusted 5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-Bromo-2-(Bromomethyl)-1,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-bromo-2- (bromomethyl) -1,3-difluorobenzene?
    5-Hydroxy-2- (hydroxymethyl) -1,3-dimethylenocene, this substance is widely used. In the field of medicine, it is often used as a key intermediate in drug synthesis. Due to its special chemical structure, it can participate in the construction of many complex drug molecules and help develop new drugs with specific curative effects. For example, it plays an indispensable role in the preparation of some antiviral and anti-tumor drugs.
    It also has important applications in materials science. It can be used to synthesize polymer materials with special properties, such as materials with good thermal stability and mechanical properties. Introducing it into polymer chains through chemical reactions can effectively improve the properties of materials, making it applicable in aerospace, electronics and other fields that require strict material properties.
    In addition, in organic synthetic chemistry, it is an extremely important organic reagent. It provides a wealth of reaction possibilities for organic synthetic chemists, helping to design and synthesize organic compounds with novel structures and unique functions. With its active functional groups, it can participate in a variety of organic reactions, such as esterification reactions, condensation reactions, etc., contributing to the development of organic synthetic chemistry. In short, 5-hydroxy- 2 - (hydroxymethyl) - 1,3-dimethylene has shown important value and wide application in many fields due to its unique chemical properties.
    What are the synthesis methods of 5-bromo-2- (bromomethyl) -1,3-difluorobenzene?
    There are many methods for the synthesis of 5-hydroxy- 2 - (hydroxymethyl) - 1,3-dithiane, and the following are common methods:
    ** 1. The method of using formaldehyde and 1,3-propanedithiol as raw materials **:
    This is a quite common method. In a suitable reaction medium, such as an organic solvent, formaldehyde and 1,3-propanedithiol can be condensed under the action of a specific catalyst. The catalysts used are often acidic catalysts, such as p-toluenesulfonic acid. During the reaction, the temperature, reaction time and other conditions need to be precisely controlled. Generally speaking, the reaction temperature is controlled in a moderate range, such as between 40 and 80 ° C. After several hours of reaction, the target product 5-hydroxy- 2 - (hydroxymethyl) - 1,3-dithiane can be formed. The principle of this reaction is that the carbonyl group of formaldehyde undergoes a nucleophilic addition reaction with the sulfhydryl group of 1,3-propanedithiol, and then condensation forms the structure of dithiane, and hydroxymethyl and hydroxyl groups are introduced at the same time.
    ** Second, the method of using the protection group strategy **:
    First protect the relevant functional groups, and then gradually build the structure of the target molecule. For example, the raw materials containing hydroxyl or mercapto groups can be protected with suitable protective groups to prevent unnecessary side reactions during the reaction process. After the basic skeleton of dithiane is constructed, the protective groups are removed through specific reaction conditions to obtain 5-hydroxy- 2 - (hydroxymethyl) - 1,3-dithiane. Although this method is slightly complicated, it is often effective to improve the selectivity and yield of the reaction. When selecting protective groups, it is necessary to select protective groups that are easy to introduce and remove according to the conditions of subsequent reactions and the characteristics of the target product.
    ** Third, the method of conversion from other sulfur-containing and oxygen-containing cyclic compounds **:
    Select suitable sulfur-containing and oxygen-containing cyclic compounds as starting materials, and modify and transform their structures through a series of chemical reactions to obtain the target product. This process may involve many reaction steps such as ring opening, ring closing, and functional group conversion. For example, some sulfur heterocyclic compounds with specific structures can be introduced into hydroxymethyl groups and hydroxyl groups through ring opening reactions under appropriate reagents and reaction conditions, and then form the structure of 5-hydroxy- 2 - (hydroxymethyl) -1,3-dithiane through ring closing reactions. However, this method requires more stringent structural requirements for the starting material, and the exploration of reaction conditions also requires more effort.
    What are the physical properties of 5-bromo-2- (bromomethyl) -1,3-difluorobenzene
    The physical properties of 5-hydroxy- 2 - (hydroxymethyl) -1,3-dioxane are very important.
    Its appearance is often a colorless to yellowish transparent liquid, and it looks like a smart water with a clear texture. Smell it, it has a weak and special smell, not pungent and unpleasant, but it is also different from odorless things, like a unique smell hidden in the air.
    When it comes to solubility, this substance is well miscible in water and alcohols such as ethanol, methanol and other organic solvents. Just like fish entering water, they can interact intimately with these solvents, regardless of each other. This property makes it extremely convenient in many chemical processes and industrial applications.
    Its boiling point is within a certain range under certain conditions, such as under standard atmospheric pressure, the boiling point value is relatively stable. This property is of great significance in distillation, separation and other operations, just like an accurate scale, providing a key reference for related processes.
    The melting point also has its own specific value. When the temperature drops to this point, the state of matter changes quietly from liquid to solid, just like water freezes in winter, and the shape changes follow its own physical laws.
    In terms of density, compared to water, it has a specific specific gravity. If it is placed in the same container as water, or floats on water, or sinks underwater, the fluctuation situation determined by its density plays a role that cannot be ignored in the process of material separation and mixing.
    5-Hydroxy-2- (hydroxymethyl) -1,3-dialkane These physical properties constitute its unique "chemical portrait", which is a key element that cannot be ignored in many fields such as chemical research and industrial production.
    Precautions for the storage and transportation of 5-bromo-2- (bromomethyl) -1,3-difluorobenzene
    5 - Mercury - 2 - (mercury methyl) - 1,3 - divinylbenzene, when storing and transporting, pay attention to many matters.
    The first is its toxicity. Mercury is a highly toxic metal, and mercury methyl compounds are especially toxic. When storing, choose a closed container with anti-leakage function to prevent the leakage of mercury and its compounds, polluting the surrounding environment, and then endangering humans and animals. During transportation, it is also necessary to ensure that the packaging is stable and does not leak.
    The second is its chemical stability. 1,3 - Divinylbenzene is active and prone to chemical reactions. When storing, avoid high temperature, open flame and strong oxidants to prevent the risk of combustion or explosion. When transporting, it is also necessary to keep away from heat and fire sources, and pay attention to shock protection, so as to avoid damage to the package due to impact and cause chemical reactions.
    The other is environmental factors. This substance is quite harmful to the environment, and the storage place should be dry and well ventilated to reduce the amount of volatilization into the air. During transportation, it is also necessary to prevent pollution to soil and water sources. If leakage unfortunately occurs, immediate and effective measures need to be taken, such as adsorption and collection with appropriate materials, to prevent its spread.
    In addition, the storage and transportation of this substance must be strictly in accordance with relevant laws and standards. Operators should be professionally trained and familiar with its hazards and emergency handling methods. Storage areas should be clearly marked with warning signs, and transportation vehicles should also be marked with corresponding dangerous goods in order to identify and respond to emergencies.
    What is the market price range for 5-bromo-2- (bromomethyl) -1,3-difluorobenzene?
    Today, there are 5-hydroxy- 2 - (hydroxymethyl) - 1,3-dithiane, and its market price range is difficult to determine. The change in prices often depends on many factors, which cannot be hidden in a single word.
    First, the supply and demand of raw materials is the main reason. If the raw materials required for its preparation are abundant and easy to obtain, the price may be stable and flat; if the raw materials are rare and difficult to purchase, the price must rise.
    Second, the process is also complicated and simple. If the preparation method is simple and consumes less manpower and material resources, the cost can be reduced and the price can be low; however, if the process is complicated, exquisite techniques and expensive tools are required, and the price should be high.
    Third, the market demand determines the price. If the demand for this product in the pharmaceutical, chemical and other industries is strong, the supply is in short supply, and the price will rise; if the demand is low, the supply exceeds the demand, and the price will fall.
    Fourth, the competition situation is related to the price. If there are many merchants producing this product in the market, the competition is fierce, and the price may drop in order to compete for share; if there are few producers, it is almost monopolized, and the price is often high.
    From this perspective, in order to determine the market price range of 5-hydroxy- 2 - (hydroxymethyl) - 1,3-dithiane, it is necessary to carefully examine the raw materials, processes, demand, and competition, and comprehensively weigh and balance to obtain a more accurate number. However, today, based on the little information given, it is difficult to determine the specific price range.