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5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene

5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene

Hongda Chemical

    Specifications

    HS Code

    269254

    Chemical Formula C7H6BrF2N
    Molar Mass 222.03 g/mol
    Appearance Typically a colorless to light - yellow liquid or solid (depending on conditions)
    Density Estimated density might be around 1.6 - 1.8 g/cm³ (estimation based on related halogenated and fluorinated aromatic compounds)
    Solubility In Water Poorly soluble in water due to the non - polar aromatic ring and hydrophobic halogen and fluorine groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate, etc., due to its organic nature
    Pka Of Amino Group The amino group in the molecule likely has a pKa in the range of 9 - 11 (estimation for aliphatic - like amino groups attached to aromatic rings)
    Reactivity The bromine atom is reactive towards nucleophilic substitution reactions; the amino group can participate in acylation, alkylation, and other reactions typical of amines

    As an accredited 5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 5 - bromo - 2 - (aminomethyl)-1,3 - difluorobenzene in 100g glass bottle packaging.
    Storage 5 - bromo - 2 - (aminomethyl)-1,3 - difluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent exposure to air and moisture, which could potentially lead to degradation or unwanted reactions. Label the storage container clearly for easy identification and safety.
    Shipping 5 - bromo - 2 - (aminomethyl)-1,3 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to chemical transport regulations to ensure safe transit, minimizing risk of leakage during handling and transportation.
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    5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene 5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene
    General Information
    Historical Development
    5-Bromo-2- (aminomethyl) -1,3-difluorobenzene is also a product of organic chemistry. At the beginning, everyone explored the field of chemistry, but their structure and properties were not well understood. However, after years of experiments and analysis, the molecular structure and characteristics were gradually understood.
    In the past, this product was synthesized, and the process was complicated and the yield was meager. Scholars worked hard to improve the technique and optimize the process. Or find new reagents, or adjust the conditions of the reaction, and after repeated trials, the synthesis method was perfected day by day.
    Its use in medicine, materials and other fields is gradually emerging. Doctors hope to use it to make effective medicines to treat human diseases; workers hope to promote technological progress with its innovative materials. Therefore, 5-bromo-2- (aminomethyl) -1,3-difluorobenzene has been little known to the public and is needed in many fields, which is one of the witnesses to the development of chemical research.
    Product Overview
    5-Bromo-2- (aminomethyl) -1,3-difluorobenzene is a chemical we are dedicated to studying. It may be a colorless to pale yellow liquid with special chemical properties. Looking at its molecular structure, bromine atoms, aminomethyl methyl and difluorobenzene rings are cleverly connected, and this unique structure gives it extraordinary potential in the field of organic synthesis.
    This compound may play a key role in the drug development path. It can be used as an important intermediate to help create new specific drugs. In the field of fine chemicals, it is also expected to contribute to the synthesis of high value-added products. We researchers should delve into its reaction mechanism and explore the best preparation method, hoping to improve the purity and yield of this product, so that it can play its due value in industrial production and scientific research, and contribute to the development and progress of chemistry.
    Physical & Chemical Properties
    5 - Bromo - 2 - (Aminomethyl) - 1,3 - Difluorobenzene is a unique chemical substance. Its physical and chemical properties are crucial. Looking at its physical properties, it is either solid at room temperature, colored or white to white powder, which is convenient for storage and use. Its melting point may be in a specific range, which can help to distinguish and purify.
    In terms of chemical properties, the groups of bromine, aminomethyl and difluorobenzene in this substance give it unique reactivity. Bromine atoms are active, can participate in nucleophilic substitution reactions, and can react with many nucleophilic reagents to derive a variety of compounds. The amino group of amino methyl group is basic and can be neutralized with acids, which is often used as a key check point in organic synthesis. The structure of difluorobenzene endows it with certain stability and special electronic effects, which affect the selectivity and rate of its chemical reaction. All these physical and chemical properties have significant uses in organic synthesis, drug development and other fields.
    Technical Specifications & Labeling
    5-Bromo-2- (aminomethyl) -1,3-difluorobenzene is a chemical I have recently studied. Its process specifications and identification (product parameters) are crucial.
    When it comes to process specifications, from the selection of raw materials, it is necessary to carefully select pure things to ensure the purity of the beginning. The reaction steps must follow the precise process, and the temperature, humidity and reaction time must be strictly controlled. If the reaction temperature or when controlled in a certain range, the duration is also fixed, so as to promote the reaction to the expected.
    As for the identification (product parameters), the appearance of this product should have a specific color and shape, and the data is accurate. The purity needs to be high, and the impurity content is minimal. Molecular weight, melting point, boiling point and other parameters also need to be clear as proof of quality. In this way, this chemical can be used in applications to show its full potential and add to related fields.
    Preparation Method
    There is a method for preparing 5 - Bromo - 2 - (Aminomethyl) - 1,3 - Difluorobenzene, which is described in detail below.
    Prepare the raw materials, take a certain (here according to the actual reaction corresponding to the name of the raw material), according to a specific process. First, make a certain and a certain in an appropriate ratio, in a container, control the temperature, and react for a number of times. This is the first step of the reaction. The purpose is to make the raw materials initially converted to obtain an intermediate product.
    times, the resulting intermediate product is separated and purified to remove impurities. Then enter another reaction environment, add a certain reagent, and control the appropriate conditions according to specific reaction steps to carry out the secondary reaction. This step further converts the intermediate product and approaches the target product.
    During this period, there is a specific catalytic mechanism. A catalyst is selected to reduce the activation energy of the reaction and promote the reaction rate, so that the reaction can proceed efficiently. After this series of steps, 5-Bromo-2- (Aminomethyl) -1,3-Difluorobenzene can be obtained, and according to this process, high purity products can be obtained.
    Chemical Reactions & Modifications
    5 - Bromo - 2 - (Aminomethyl) - 1,3 - Difluorobenzene, its chemical and reverse modification, is an important research topic. We explore the reaction of this compound, in order to clarify its characteristics, in order to achieve the purpose of modification.
    Its chemical and reverse properties, or involving nuclear substitution, or oxidizing. The nuclear substitution, the specific nuclear attack its active site, leading to General knowledge, insight into its anti-law, application of modification methods, in order to make this compound in the field of better use, such as chemical synthesis, material research, to add a new chapter of research.
    Synonyms & Product Names
    5-Bromo-2- (aminomethyl) -1,3-difluorobenzene, in the field of chemistry, its synonymous name and the name of the commodity are all important for our investigation.
    Now look at this thing, its synonymous name, or according to the structural characteristics, or the past name, and so on. Chemists based on theory, from the molecular structure, atomic combination, etc., get different expressions to refer to the same substance.
    As for the name of the product, the merchant sells it, or takes the name of easy to remember, or has the meaning of characteristics, hoping to attract attention. Or show its purity, or show its use, to be different from other things.
    In this way, the synonymous name and the name of the commodity, although expressed differently, both refer to this 5-bromo-2 - (aminomethyl) -1,3-difluorobenzene, which has its own uses in chemical research and commercial transactions, to help us understand its nature and general use.
    Safety & Operational Standards
    5-Bromo-2- (aminomethyl) -1,3-difluorobenzene Safety and Operating Specifications
    F 5-bromo-2- (aminomethyl) -1,3-difluorobenzene is also an important product for chemical research. If you want to use this product, the first priority is safety, and you should follow the operating specifications to keep it safe.
    As far as storage is concerned, it should be placed in a cool, dry and well-ventilated place. Avoid water and fire, and keep it away from heat sources to prevent it from changing due to environmental discomfort. Hold it in a sealed device to prevent it from coming into contact with foreign objects to avoid deterioration.
    During operation, take care of protective equipment. Wear special gloves to avoid skin contact and invasion; wear protective goggles to protect your eyes from being invisible; wear protective clothing to protect your whole body from harm.
    When taking it, the action should be slow and careful. Use a clean device, take it according to the quantity, and don't be greedy for too much. In the operation room, keep the air flowing smoothly to avoid risk caused by gas accumulation.
    If you accidentally touch it, rinse it with plenty of water as soon as possible. If you touch the skin, rinse it for medical treatment according to the situation; if you enter the eyes, you must wash it urgently, and seek medical consultation quickly, without delay.
    After use, properly dispose of the remaining items. Do not discard them at will, according to environmental protection regulations, classify them to avoid polluting the environment and leaving disasters behind.
    In short, the safety and operation of 5-bromo-2- (aminomethyl) -1,3-difluorobenzene should be meticulously kept in mind, so as to ensure the smooth operation of the experiment, the safety of personnel, and the cleanliness of the environment.
    Application Area
    5 - Bromo - 2 - (Aminomethyl) - 1,3 - Difluorobenzene is an important chemical substance. Its application field is quite extensive. In the field of medicinal chemistry, it may be used as a key intermediate to assist in the synthesis of new drugs and the development of specific drugs for specific diseases. In the field of materials science, it may be able to participate in the preparation of functional materials, giving materials unique properties, such as excellent electrical conductivity or optical properties. In the field of organic synthesis chemistry, this compound can act as a starting material, through a series of chemical reactions, to construct complex organic molecular structures, open up new paths for organic synthesis, promote the progress of chemical synthesis technology, and play an indispensable role in many chemistry-related research and industrial practices.
    Research & Development
    Today there is a product called 5 - Bromo - 2 - (Aminomethyl) -1,3 - Difluorobenzene. As a researcher, we have dedicated ourselves to studying its properties and applications. In the laboratory, after every attempt, we investigated the characteristics of its reaction and studied the good method of synthesis.
    At the beginning, the raw material ratio was slightly poor, resulting in impure products. After repeated thinking, adjusting parameters, optimizing the process, and gradually getting the best method. This compound has great potential in the fields of pharmaceutical research and development, materials science, etc. We are determined to use this material to open up new horizons, contribute to the progress of scientific research, and promote its wide application, so as to benefit the world. We hope to move forward steadily and achieve remarkable results in the future of scientific research, so as to promote the development of this compound and make it beneficial to the public.
    Toxicity Research
    Today there is a substance, called 5 - Bromo - 2 - (Aminomethyl) - 1,3 - Difluorobenzene, in our chemical research. The investigation of the toxicity of this substance is the most important.
    Detailed investigation of this substance, its molecular structure is unique, containing bromine, aminomethyl and difluorobenzene groups. Toxicity studies are the first to focus on its impact on organisms. After various experiments, observe its interaction with biological cells, observe changes in cell morphology, growth and metabolism.
    It also explores its behavior in the environment, and considers its stability and migration in water, soil and other media. Knowing its toxicity can make good use of it, avoid its harm, and ensure the safety of human beings and the environment. Therefore, toxicity research should not be slack, and caution should be taken to achieve harmony between chemical research and application.
    Future Prospects
    Wuguan 5 - Bromo - 2 - (Aminomethyl) - 1,3 - Difluorobenzene is unique and has a wide range of uses. In the field of pharmaceutical research and development, it is expected to become a key intermediate, help create new drugs with specific effects, and heal many diseases. In the field of materials science, it may contribute to the synthesis of new materials and give materials specific properties.
    In the future, with the advancement of scientific research, its synthesis process will be more exquisite, the cost will be reduced and the yield will be improved. It is also expected to expand the scope of application and enter emerging fields such as electronics and environmental protection. The potential of this material is like a flower that has not yet bloomed. Over time, it will be able to shine in various fields, adding luster to human well-being. Its broad prospects are full of longing, and it is hoped that it will glow with endless vitality and value in the future.
    Where to Buy 5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene in China?
    As a trusted 5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-bromo-2- (aminomethyl) -1,3-difluorobenzene?
    5 + -Ether-2- (hydroxymethyl) -1,3-diethyl ether, this substance is an organic compound, its main use is wide, and it has important effects in various fields.
    In the field of organic synthesis, it is often used as a solvent. Because of its good solubility, it can evenly disperse many organic substances, just like creating a stable "habitat", so that chemical reactions can be carried out smoothly and orderly. For example, in the preparation of many fine chemicals, it is like a right-hand assistant, assisting the reactants to blend with each other to improve the reaction efficiency and product purity.
    In the pharmaceutical industry, it also has key uses. In the synthesis path of some drugs, it actively participates as a solvent or reaction intermediate. For example, in the manufacturing process of some specific pharmaceutical ingredients, it can precisely regulate the reaction conditions, help generate products that meet pharmaceutical standards, and lay a solid foundation for drug quality.
    In addition, in the coatings and adhesives industry, 5 + -ether-2- (hydroxymethyl) -1,3-diethyl ether also plays an important role. In the coating system, it can adjust the viscosity and drying speed of the coating, so that the coating is applied more evenly, the film formation effect is better, and the aesthetics and protective properties of the coating are enhanced. In adhesives, it helps to improve the fluidity of the adhesive and the wettability of the adhesive, thereby strengthening the adhesive strength and ensuring a stable and lasting bonding effect.
    In short, 5 + -ether-2- (hydroxymethyl) -1,3-diethyl ether plays an indispensable role in many fields such as organic synthesis, medicine, coatings and adhesives due to its unique physical and chemical properties. It is like a shining "industrial pearl" and contributes an important force to the development of various industries.
    What are the synthesis methods of 5-bromo-2- (aminomethyl) -1,3-difluorobenzene
    To prepare 5-hydroxy-2- (ethylamino) -1,3-diphenyl ether, there are various methods.
    First, it can be obtained by the reaction of the corresponding halogenated phenyl ether and ethylamine through nucleophilic substitution. First take a suitable halogenated phenyl ether, place it in a reactor, dissolve it with an appropriate organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., add an appropriate amount of ethylamine, and add potassium carbonate, sodium carbonate and other bases to bind the acid to promote the reaction. Stirring at controlled temperature, depending on the activity of halogenated phenyl ether and the amount of ethylamine, the temperature may be between room temperature and 80 ° C, and the product can be purified by column chromatography or recrystallization.
    Second, start with phenolic compounds. First, phenol and halogenated ethane are formed into ethers under the action of bases, such as phenol and bromoethane, which are reacted in sodium hydroxide or potassium hydroxide alcohol solution to form ethoxy phenols. Then, amino groups are introduced through nitrification and reduction. Nitrify with mixed acid of nitric acid and sulfuric acid to obtain nitroethoxy phenol, and then add hydrochloric acid to iron powder, zinc powder, etc., or hydrogen is reduced under a catalyst such as palladium carbon to obtain aminoethoxy phenol. Finally, it reacts with another halogenated phenyl ether to form 5-hydroxy-2- (ethylamino) -1,3-diphenyl ether, and subsequent purification operations are required.
    Third, the Ullmann reaction variant can be used. Select suitable halogenated aromatics and phenolic derivatives, use copper salts as catalysts, such as cuprous iodide, ligands such as 1,10-phenanthroline, bases such as cesium carbonate, etc., heat reaction in organic solvents to construct diphenyl ether structures, and then modify amino and hydroxyl groups to obtain the target product. The reaction conditions need to be carefully regulated, and the temperature, catalyst and ligand dosage are all related to the reaction efficiency and product purity.
    Each of these methods has its own advantages and disadvantages. In practice, it is necessary to weigh the availability of raw materials, costs, and reaction conditions, and choose the right one.
    What is the market price of 5-bromo-2- (aminomethyl) -1,3-difluorobenzene?
    Today, there is 5-hydroxy- 2 - (ethylamino) - 1,3 - dithiane, what is the market? This is the price of chemical materials, and the market is often affected by many factors.
    The cost of raw materials is one of the factors. The cost of raw materials required to make this compound is affected by the supply of raw materials, the ease of production, and the cost of raw materials. If the supply of raw materials is low, or the degree of improvement is high, the cost of raw materials will rise, which will lead to the market of 5-hydroxy- 2 - (ethylamino) - 1,3 - dithiane.
    The production industry is also heavy. If the production cost is low, high-end and exquisite skills are required, and the cost of production will increase, and the market price will also be higher. And the production cost of efficient production first may reduce the cost and make the price more reasonable.
    The supply and demand system of the city is even more low. If the demand for 5-hydroxyl-2- (ethylamino) -1,3-dithiane is strong in the market, and the supply is limited, the price will rise; conversely, if the supply is low and the demand is low, the price will easily decline.
    In addition, different companies have poor or poor quality, and those with high quality often have higher prices. And factors such as sales channels and regions also make the market different.
    Therefore, in order to know the market value of 5-hydroxy- 2 - (ethylamino) - 1,3 - dithiane concentrate, it is advisable to add information to the chemical raw material trading platform, the phase operator or the producer, in order to obtain the detailed information.
    What are the storage conditions for 5-bromo-2- (aminomethyl) -1,3-difluorobenzene?
    5 + -Hg-2- (hydroxymethyl) -1,3-divinylbenzene is an important organic compound, and its storage conditions are very critical.
    This compound should be stored in a cool and well-ventilated place. Because it is sensitive to heat, high temperature can easily change its properties and even cause dangerous reactions, so a cool environment can effectively maintain its chemical stability.
    At the same time, it is necessary to ensure that the storage area is dry. The presence of moisture may promote reactions such as hydrolysis, which in turn affects its quality and purity. Humid environments can easily cause the compound to deteriorate with moisture and cannot meet subsequent use needs.
    Furthermore, keep away from fire and heat sources. 5 + -Hg-2- (hydroxymethyl) -1,3-divinylbenzene has a certain flammability. In case of open flame and high heat energy, it will cause combustion and explosion. Therefore, staying away from fire and heat sources is an important measure to ensure storage safety.
    In addition, it should be stored separately from oxidants and food chemicals, and mixed storage should not be avoided. Due to its active chemical properties, severe redox reactions may occur in contact with oxidants, while mixed storage with food chemicals may cause serious consequences such as accidental ingestion, threatening human health.
    The container in which the substance is stored should be well sealed to prevent it from evaporating or reacting with external substances. Seal the container in time after use to avoid oxidation or absorption of moisture in the air due to long-term contact with the air, and maintain its original chemical properties. Regularly check the storage area to see if the container is damaged or leaked, so as to detect and deal with problems in time to ensure safe storage.
    What are the physicochemical properties of 5-bromo-2- (aminomethyl) -1,3-difluorobenzene
    5-Hydroxy-2- (ethylamino) -1,3-dibenzofuran, this substance has unique physical and chemical properties. Its appearance is often crystalline solid, the texture is relatively fine, and it is quite stable at room temperature and pressure. The melting point is about [X] ° C. This temperature makes it change from solid to liquid in a specific environment, which brings specific requirements for related process operations.
    In terms of solubility, it is difficult to dissolve in water because its molecular structure lacks a group that strongly interacts with water molecules, resulting in very low dispersion in water. However, it is soluble in some organic solvents, such as ethanol, dichloromethane, etc. In ethanol, by virtue of the van der Waals force between molecules and the possible weak interaction, it can be well dispersed and dissolved, which facilitates the preparation of solutions in organic synthesis and drug preparation.
    From the perspective of chemical properties, its benzofuran structure endows it with certain aromaticity, making it able to participate in some typical reactions of aromatic compounds, such as electrophilic substitution reactions. Under suitable reaction conditions and catalysts, the hydrogen atoms on its benzene ring can be replaced by other functional groups, resulting in a series of derivatives with different biological activities and physical properties, which have potential applications in the field of medicinal chemistry. At the same time, the hydroxyl group and ethylamino group in the molecule also bring it unique reactivity, the hydroxyl group can undergo esterification, etherification and other reactions, and the ethylamino group can participate in nucleophilic reactions, etc. These reaction characteristics provide a rich way for its chemical modification and functionalization.