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5-Bromo-1-Chloro-2,4-Difluorobenzene

5-Bromo-1-Chloro-2,4-Difluorobenzene

Hongda Chemical

    Specifications

    HS Code

    963397

    Chemical Formula C6H2BrClF2
    Molar Mass 231.43 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 182 - 184 °C
    Density 1.81 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Purity Typically high - purity products are 95%+
    Cas Number 102033 - 62 - 1

    As an accredited 5-Bromo-1-Chloro-2,4-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 5 - bromo - 1 - chloro - 2,4 - difluorobenzene in 100 - gram glass bottles for packaging.
    Storage Store 5 - bromo - 1 - chloro - 2,4 - difluorobenzene in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Avoid storing near oxidizing agents or substances that could react with it. Label the storage container clearly for easy identification.
    Shipping 5 - bromo - 1 - chloro - 2,4 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safety during transit, avoiding exposure and potential spills.
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    5-Bromo-1-Chloro-2,4-Difluorobenzene 5-Bromo-1-Chloro-2,4-Difluorobenzene
    General Information
    Historical Development
    5-Bromo-1-chloro-2,4-difluorobenzene is also an organic compound. It first appeared in research, due to the diligence of many scholars. At the beginning, the synthesis method was still simple, and the yield was not abundant. However, as the years passed, the researchers were reluctant to give up, using their methods to refine their techniques. Gradually, the synthesis path became clearer and the efficiency gradually increased. In the past, the preparation was difficult, and it was often difficult for everyone. The choice of raw materials and the control of conditions need to be cautious. Today, however, with the improvement of skills, this compound can be obtained in a better way, and it is widely used in the fields of medicine and materials. The way of its development really depends on the study of various sages, so that the ability of this compound can be developed in the world, which is for the prosperity of all industries, adding bricks and tiles, and the prospect is promising.
    Product Overview
    5-Bromo-1-chloro-2,4-difluorobenzene is also an organic compound. Its shape may be a colorless liquid with a special taste. This substance is widely used in the field of chemical industry.
    Its preparation method, or through multi-step reaction, can achieve a pure state. Its molecular structure is unique, and the atoms of bromine, chlorine and fluorine are connected to the benzene ring, resulting in its chemical properties.
    In the reaction, it can often be used as an intermediate and participate in a variety of organic synthesis. Because it contains halogen atoms, it can react with many reagents such as substitution and addition, and is a key raw material for the synthesis of complex organic molecules.
    When using it, pay attention to safety. Because it may be toxic and corrosive, it must be followed when operating to ensure personal and environmental safety. In short, 5-bromo-1-chloro-2,4-difluorobenzene is of great value in chemical research and industrial production.
    Physical & Chemical Properties
    5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene is an organic compound, and its physicochemical properties are very important. Looking at its physical properties, at room temperature, this substance is mostly in the state of colorless to light yellow liquid, with a specific odor. Its boiling point and melting point are stable in a specific temperature range. Due to the presence of halogen atoms in the molecular structure, its density is higher than that of common organic solvents.
    When it comes to chemical properties, the halogen atom of this compound is very active. The electronegativity difference of bromine, chlorine and fluorine atoms makes the electron cloud of the benzene ring uneven. This property makes it easy to participate in nucleophilic substitution reactions, and the halogen atom on the aromatic ring can be replaced by nucleophilic reagents. At the same time, under specific conditions, electrophilic substitution reactions can also occur, exhibiting unique chemical activity and having important application value in the field of organic synthesis.
    Technical Specifications & Labeling
    5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene is an important chemical substance. Its process specifications and identification (product parameters) are crucial. The purity of this product needs to reach a very high level, and the impurity content should be strictly controlled to a minimum. The appearance should be a colorless and transparent liquid with no visible foreign matter. Physical parameters such as boiling point and melting point also need to be accurately measured and recorded to identify the key quality. The chemical properties are stable and do not react easily under specific conditions. The production process needs to follow a strict process flow to ensure that all links are accurate, so as to ensure that the product quality is uniform and meets the established process specifications and labeling requirements, so as to meet the needs of various application scenarios.
    Preparation Method
    5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene is an important chemical substance. The preparation method is as follows:
    In terms of raw materials, specific halogenated aromatics and corresponding halogenated reagents need to be prepared. The synthesis process is quite critical. First, the halogenated aromatics and the brominating reagent are reacted under suitable reaction conditions, such as at a specific temperature and in the presence of a catalyst, to introduce bromine atoms. Then, the chlorination reagent and the fluorination reagent are added, and the reaction is carried out in sequence.
    The reaction steps are rigorous, and each step requires precise control of the reaction time, temperature and the ratio of reactants. In the bromination step, if the temperature is too high or the time is too long, side reactions may occur; the same is true for the chlorination and fluorination steps. In the
    activation mechanism, the catalyst can effectively reduce the activation energy of the reaction and promote the smooth progress of the reaction. In this way, through careful preparation of raw materials, strict control of reaction steps and activation mechanism, 5-Bromo-1-Chloro-2,4-Difluorobenzene can be efficiently prepared.
    Chemical Reactions & Modifications
    There is a chemical substance today, named 5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene. In the field of chemical research, its reaction and modification are crucial.
    Looking at this substance, its structure is unique and the arrangement of atoms is orderly. To understand its reaction, it is necessary to study the force between molecules and observe the change of its electron cloud. When encountering a specific reagent, the covalent bond is broken or connected, and a new product is formed.
    Regarding its modification, it can be modified by means of substitution and addition. Using a suitable group to replace its atom can change its physical and chemical properties. If attacked with nucleophilic reagents, bromine, chlorine or fluorine can be substituted to obtain new derivatives, or with better stability and activity, which can be used in various fields of medicine and materials.
    Our chemical researchers should study its reaction mechanism carefully and make good use of modification techniques to explore more possibilities for the advancement of science and industry.
    Synonyms & Product Names
    5-Bromo-1-chloro-2,4-difluorobenzene is also a chemical material. In my chemical research, this substance is worth paying attention to. Its alias is also important to us.
    The alias of this substance may be called differently due to different regions, habits, or academic schools. However, its essence refers to this specific chemical substance. As far as the name of business is concerned, merchants may give it a different name in order to recognize its characteristics, facilitate its promotion, or give it a different name.
    Although the names are different, they all point to this 5-bromo-1-chloro-2,4-difluorobenzene. When I am researching, I need to clarify all the synonyms and trade names in order to be accurate and not confused in various documents and exchanges, so as to facilitate the smooth progress of research and explore its chemical mysteries, for both academic and practical purposes.
    Safety & Operational Standards
    5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene is an important chemical substance. Careful attention must be paid to its safety and operating practices.
    When handling this substance, the first priority is safety protection. The operator must wear appropriate protective clothing, such as laboratory clothes, gloves and goggles. Gloves should be chemically resistant to corrosion to prevent skin contact and damage. Goggles can effectively protect the eyes and prevent the substance from splashing and causing damage.
    Furthermore, the operating environment is also crucial. It should be carried out in a well-ventilated place, preferably in a fume hood. This can allow the volatile gas to be discharged in time, reduce the concentration of the substance in the air, and reduce the risk of inhalation. If inhaled inadvertently, it should be removed to a fresh air place immediately. If the symptoms are serious, seek medical attention immediately.
    For storage, 5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene should be stored in a cool, dry place away from sources of ignition and oxidants. Store in a well-sealed container to prevent it from evaporating or reacting with other substances.
    During use, the substance must be used accurately and according to the amount required for experiment or production to avoid waste and unnecessary risks. After operation, used utensils should be properly cleaned and disposed of to prevent residual substances from causing harm.
    In conclusion, the safety and operation regulations for 5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene should be strictly followed and must not be slack to ensure the safety of personnel and the smooth operation.
    Application Area
    5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene is a unique chemical substance with considerable application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities. With its unique chemical structure, it can ingeniously introduce specific functional groups and precisely regulate the activity and selectivity of drugs, which has great potential in the field of disease treatment.
    In the field of materials science, it also has extraordinary performance. Or it can participate in the creation of high-performance materials, such as polymers with special functions. Because of its halogen atoms, it can endow materials with unique physical and chemical properties, such as enhancing stability and changing electrical properties, and play an important role in the development of advanced materials. In the field of fine chemicals, it is also an important raw material for the synthesis of specialty chemicals, contributing to the diversified development of the chemical industry.
    Research & Development
    I have been studying chemistry for a long time, and recently I focused on the investigation of 5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
    I began to investigate its structure to clarify its reactivity check point. After repeated experiments, it was found that it can substitution react with various reagents under specific conditions, and the selectivity is quite good. This property may pave the way for the development of new drugs and materials.
    However, the research is not smooth sailing, and the control of reaction conditions and the inhibition of side reactions are difficult problems. I studied day and night, consulted ancient books and classics, and exchanged ideas with colleagues.
    Although there is progress today, there is a long way to go. I should make unremitting efforts to tap its potential and hope to make breakthroughs, so that this compound can shine in the field of industrial production and scientific research, and contribute to the development of chemistry.
    Toxicity Research
    I have tried to study the properties of poisons. Recently, 5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene focused on this substance. It is a halogenated aromatic hydrocarbon with a special structure and contains bromine, chlorine and fluorine halogen atoms.
    Halogenated aromatics are mostly toxic because they can react with biological macromolecules. 5 - Bromo - 1 - Chloro - 2,4 - Difluorobenzene has different atomic activities of bromine, chlorine and fluorine, or affects its toxicity. Fluorine atoms are strong electronegativity, or make molecules more lipophilic, easy to pass through biological membranes and enter cells to cause toxicity.
    It may be persistent in the environment and enriched through the food chain. If aquatic organisms touch it, their physiological functions may be damaged. And this substance may be genotoxic and interfere with the transmission and expression of biological genetic information. Therefore, its production and use should be carefully studied for toxicity to protect the ecology and human well-being.
    Future Prospects
    I have tried to study the technology of chemical industry, and I have especially worked hard on this material 5 - Bromo - 1 - Chloro - 2, 4 - Difluorobenzene. Although I have achieved something today, I still have great dreams when thinking about the future.
    Looking at this compound, it has a wide range of uses and can be used in the fields of medicine and materials. In the future, science and technology will be new, medicine will be more refined, and materials will be stronger. This compound may help medicine to make special agents to treat serious diseases; it can also add novelty to materials and meet the needs of changes.
    I have been working together with my colleagues to explore the deeper secrets of this substance and expand its application. With time, we will be able to make it shine in the future, for the well-being of the world, for the world of science and technology to add brilliance, live up to our original intention of research, into the unfinished business.
    Where to Buy 5-Bromo-1-Chloro-2,4-Difluorobenzene in China?
    As a trusted 5-Bromo-1-Chloro-2,4-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-Bromo-1-Chloro-2,4-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-Bromo-1-Chloro-2,4-Difluorobenzene?
    5-Bromo-1-chloro-2,4-difluorobenzene is also an organic compound. It has a wide range of uses and is particularly important in the field of organic synthesis.
    First, it can be used as an intermediate in pharmaceutical synthesis. During the preparation of many drugs, this compound can introduce key functional groups through specific chemical reactions to help build the structure of drug-active molecules. For example, when developing new antibacterial drugs or antiviral drugs, it can be used as a starting material to precisely construct a molecular structure with specific pharmacological activities through multi-step reactions, and then provide the necessary basic materials for pharmaceutical research and development.
    Second, it also has important functions in the field of pesticide synthesis. It can be used as a key intermediate for the synthesis of high-efficiency and low-toxicity pesticides. By reacting with other chemical substances, pesticide products with unique insecticidal, bactericidal or herbicidal properties can be generated. Taking the synthesis of new insecticides as an example, 5-bromo-1-chloro-2,4-difluorobenzene participates in the reaction, which can endow pesticides with better biological activity and environmental adaptability, and meet the needs of modern agriculture for efficient and environmentally friendly pesticides.
    Third, it also has its uses in materials science. When synthesizing polymer materials with special properties, this compound can participate in the polymerization reaction as a functional monomer. Polymer materials made in this way may have unique electrical and optical properties, which can be applied to fields such as electronic devices and optical films, injecting new vitality into the development of materials science.
    In short, 5-bromo-1-chloro-2,4-difluorobenzene plays an indispensable role in many fields such as medicine, pesticides and materials due to its unique chemical structure. It is of great significance to promote technological progress and industrial development in related fields.
    What are the physical properties of 5-Bromo-1-Chloro-2,4-Difluorobenzene?
    5-Bromo-1-chloro-2,4-difluorobenzene is also an organic compound. Its physical properties, let me tell them one by one.
    This compound is mostly liquid at room temperature, and its color is colorless and transparent, or slightly colored. It has a flowing state and feels like an ordinary liquid to the touch. Its smell, or has a special aroma, or has a slightly different taste, and its unique smell can be sensed by smelling.
    As for its boiling point, it is usually in a certain temperature range due to factors such as intermolecular forces. When heated to a specific temperature, it will change from liquid to gas and undergo gasification. The melting point is also fixed. When the temperature drops to a certain value, it will solidify from liquid to solid.
    Its density is different from that of water, or it floats on water, or it sinks underwater, depending on its specific value. In terms of solubility, in organic solvents, such as ethanol, ether, etc., it may have a certain solubility and can be mixed with it. However, in water, due to its organic properties, the solubility may be very small, and it is difficult to miscible with water.
    The physical properties of this compound are its inherent properties. It is of great significance in the application of chemical industry, medicine and many other fields. It is related to its separation, purification, and setting of reaction conditions.
    Is 5-Bromo-1-Chloro-2,4-Difluorobenzene Chemically Stable?
    The chemical properties of 5-bromo-1-chloro-2,4-difluorobenzene are stable? This is a question about the characteristics of organic compounds. To determine its stability, when looking at its molecular structure.
    In this compound, the benzene ring has a conjugated system to make it stable. However, there are halogen atoms of bromine, chlorine and fluorine attached to the benzene ring. The halogen atom has an electron-absorbing induction effect, which can reduce the electron cloud density of the benzene ring.
    The electronegativity of bromine, chlorine and fluorine is different, but the electronegativity of fluorine is particularly large, and its electron-absorbing ability is strong. The coexistence of multiple halogen atoms increases the uneven distribution of electron clouds in the benzene ring. Although the benzene ring conjugated system has the power to maintain stability, the electron-withdrawing effect of the halogen atom should not be underestimated.
    Under normal conditions, 5-bromo-1-chloro-2,4-difluorobenzene is relatively stable. However, under extreme conditions such as strong nucleophiles, strong oxidants or high temperatures, halogen atoms may react and cause molecular structure changes.
    For example, in an alcohol solution of a strong base and under heating conditions, halogen atoms may undergo elimination reactions; in the case of strong oxidants, benzene rings may be oxidized. Therefore, its stability is relative, not absolute.
    What is the production method of 5-Bromo-1-Chloro-2,4-Difluorobenzene?
    The preparation of 5-bromo-1-chloro-2,4-difluorobenzene is the key to the chemical process. The method is usually achieved by using a specific starting material and many chemical reaction steps.
    Common starting materials, or compounds containing benzene rings, which have functional groups that can be converted into bromine, chlorine, and fluorine substituents.
    First step, or halogenation reaction. If a suitable brominating agent, such as bromine (Br ²) and a catalyst, is used under suitable reaction conditions, the bromine atom is introduced into the benzene ring at a specific position. This reaction condition needs to be precisely controlled, such as temperature, reaction time, proportion of reactants, etc., all of which have a great influence on the selectivity and yield of the reaction products.
    The second step is the introduction of chlorine atoms. Chlorinated reagents, such as thionyl chloride (SOCl ²), can be used to connect the benzene ring to chlorine atoms at a specific check point in a catalyst or a specific reaction medium. This process also requires fine regulation of the reaction parameters to ensure that the chlorine atoms are replaced in the expected position.
    As for the introduction of fluorine atoms, it is often caused by a nucleophilic substitution reaction. A suitable fluorine source, such as potassium fluoride (KF), is selected to react with a benzene ring intermediate containing a suitable leaving group in the presence of an organic solvent and a phase transfer catalyst, so that the fluorine atom is introduced into the specific position of the benzene ring.
    The whole preparation process requires quite high requirements for reaction equipment and operation skills. After each step of the reaction, it is often necessary to separate and purify the process, such as distillation, extraction, recrystallization, etc., to obtain the high-purity 5-bromo-1-chloro-2,4-difluorobenzene product. In this way, the compound can be effectively prepared through a multi-step chemical reaction and fine operation.
    What to pay attention to when storing and transporting 5-Bromo-1-Chloro-2,4-Difluorobenzene
    5-Bromo-1-chloro-2,4-difluorobenzene is an organic compound, and many matters need to be paid more attention when storing and transporting it.
    First of all, the nature of this compound may be more active, and it should be placed in a cool, dry and well-ventilated place. Because the substance is afraid of heat, if it is placed in a high temperature environment, it may cause decomposition, volatilization, etc., which may damage its quality or even cause safety problems. Therefore, the temperature of the storage place should be strictly controlled within the appropriate range, and it should not be too high.
    Furthermore, this compound is sensitive to moisture or moisture, encounters water or water vapor, or reacts chemically, so the storage place must be kept dry, and a desiccant can be prepared to remove water vapor.
    And 5-bromo-1-chloro-2,4-difluorobenzene may be toxic and corrosive, and should be stored separately from oxidizing agents, reducing agents, acids, bases and other substances to prevent mutual reaction. Storage containers are also crucial. Material adapters must be selected to ensure that there is no risk of leakage, and the name of the compound and relevant warning labels should be clearly marked on the outside of the container.
    As for transportation, transportation personnel must be familiar with its characteristics and emergency treatment methods. During transportation, ensure that the container is stable, avoid collisions, vibrations, and prevent damage and leakage. Transportation vehicles should also be well ventilated, and equipped with corresponding emergency equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, protective gloves, gas masks, etc.
    If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the surrounding personnel, isolate the leakage area, and strictly prohibit fire from approaching. When a small amount of leakage occurs, it can be absorbed by inert materials such as sand and vermiculite; when a large amount of leakage occurs, it is necessary to build a dike or dig a pit for containment, and then properly handle it.
    In conclusion, when storing and transporting 5-bromo-1-chloro-2,4-difluorobenzene, care should be taken with regard to temperature, humidity, storage conditions, container selection, and transportation protection to ensure safety and avoid accidents.