5-Bromo-1,3-difluoro-2- (trifluoromethoxy) benzene, an organic compound, is widely used in chemical and scientific research fields.
Its primary use is to act as an intermediate in pharmaceutical synthesis. In the process of modern pharmaceutical research and development, the creation of many special drugs often requires the help of such organic compounds with unique structures. Because it contains special functional groups such as bromine, fluorine and trifluoromethoxy, it can endow drugs with specific chemical properties and biological activities. For example, in the synthesis of some antibacterial and antiviral drugs, 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene can be used as a key starting material. After multiple steps of delicate chemical reactions, the complex molecular structure of the drug is gradually built, laying the foundation for the efficacy of the drug.
Furthermore, in the field of pesticides, this compound also has important value. With the increasing demand for high-efficiency, low-toxicity and environmentally friendly pesticides in modern agriculture, 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene can be derived from a series of pesticide products with excellent performance due to its unique chemical structure. Such as new insecticides, fungicides, etc., with their special functional groups and the specificity of the mechanism of action of pests and pathogens, to achieve precise and efficient control effect, and relatively small impact on the environment, in line with the current trend of green agriculture development.
In addition, in the field of materials science, 5-bromo-1,3-difluoro-2 - (trifluoromethoxy) benzene has also emerged. Researchers have found that introducing it into the synthesis process of polymer materials can significantly improve the properties of materials. For example, improve the thermal stability, chemical stability and electrical properties of materials. In the field of electronic materials, the use of this compound to participate in the preparation of new materials is expected to be applied to high-performance electronic devices, to help improve the performance of electronic devices and miniaturization development.
In conclusion, although 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene is an organic compound, it plays an indispensable role in many important fields such as medicine, pesticides and materials science due to its special structure and properties, and promotes the continuous progress and development of various fields.

5-Bromo-1,3-difluoro-2- (trifluoromethoxy) benzene, also an organic compound. It has various physical properties, which are detailed as follows.
First of all, its phase and color are mostly colorless to pale yellow transparent liquids at room temperature and pressure. Looking at it, it has a clear and translucent appearance, and there is no turbidity, precipitation and other abnormalities. Due to its molecular structure arrangement and intermolecular forces, it can maintain liquid stability at room temperature.
times and boiling point, between about 140-145 ° C. When the external pressure is standard atmospheric pressure, at this temperature, the molecule of the compound is sufficiently energized to break free from the attractive forces between molecules and change from liquid to gaseous state. This boiling point value is the result of the combined action of its molecular mass and intermolecular forces (such as van der Waals force, dipole-dipole force, etc.). The presence of halogen atoms and methoxy groups in the molecule increases the intermolecular forces, resulting in a relatively high boiling point.
Furthermore, the melting point is in the range of -20 ° C to -15 ° C. When it drops to Swain, the thermal motion of the molecules weakens, the orderly arrangement is enhanced, and then the liquid state condenses into a solid state. The range of melting point is also closely related to the molecular structure. Molecular symmetry, polarity and other factors all affect the melting point. The molecular structure of this compound is slightly complex and the polar distribution is uneven, so the melting point is in this range.
When it comes to density, it is about 1.8-1.9 g/cm ³. The density depends on the molecular weight and the degree of compactness of intermolecular stacking. The compound contains elements with relatively large atomic mass such as bromine and fluorine, and the molecular structure is compact, resulting in a high unit volume mass.
In terms of solubility, it has good solubility in organic solvents such as dichloromethane, chloroform, toluene, etc. Due to the principle of "similar miscibility", its molecules have a certain polarity, which is similar to the polar phase of the above organic solvents, and can form a favorable interaction between the molecules, so they are miscible. However, the solubility in water is very small, because water is a strong polar solvent, it does not match the intermolecular force of the compound, and it is difficult to miscible with each other.
The physical properties of 5-bromo-1,3-difluoro-2 - (trifluoromethoxy) benzene are determined by its unique molecular structure, and in the fields of organic synthesis and chemical production, it is of great significance to control its separation, purification, and reaction conditions.

There are several methods for the synthesis of 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene.
First, bromobenzene derivatives are used as starting materials. First, appropriate bromobenzene is taken, and fluorine atoms are introduced under specific reaction conditions. This process requires careful selection of reaction reagents and reaction environments. For example, using a suitable fluorinating agent, under specific temperature, pressure and catalyst, the bromine atom is gradually replaced by a fluorine atom to form a bromine-containing benzene intermediate with difluoro substitution. Subsequently, this intermediate is reacted with a reagent containing trifluoromethoxy. This reaction also needs to be precisely regulated to ensure that the trifluoromethoxy group is smoothly connected to the designated position of the benzene ring, and the final product is 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene.
Second, start from fluorobenzene. Select the appropriate derivative containing difluorobenzene and carry out the bromination reaction first. Select the appropriate brominating reagent, and introduce bromine atoms at the appropriate position in the benzene ring according to its reactivity and selectivity to form a benzene intermediate where bromine and fluorine coexist. After that, using specific reaction conditions, the intermediate interacts with a reactant that can provide trifluoromethoxy, and through a series of reaction steps, the trifluoromethoxy group is successfully connected to the benzene ring to achieve the synthesis of 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene.
Third, the cross-coupling reaction strategy is carried out with halogenated aromatics as raw materials. First select a suitable halogenated aromatic hydrocarbon, whose halogen atom can form an active intermediate with the metal reagent. At the same time prepare a metal-organic reagent containing trifluoromethoxy. The two are cross-coupled under the action of catalysts. By precisely controlling the reaction conditions, such as temperature, solvent, catalyst type and dosage, the two are coupled to gradually construct the structure of the target molecule, and finally synthesize 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene. Each method has its own advantages and disadvantages, and the appropriate synthesis path needs to be weighed according to actual needs and conditions.

I look at your question, but I am inquiring about the price range of 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene in the market. However, the price of this product often changes due to many factors, and it is difficult to determine the exact number.
First, different manufacturers have different processes and costs, resulting in different prices. Large factories may reduce costs slightly due to scale effects, but product quality control is strict, or it may affect pricing. Although the cost of small factories is low, if the quality is not good, the price will also change.
Second, the relationship between market supply and demand is the main reason. If there are many people who want it, but there are few products, the price will rise; on the contrary, if the supply exceeds the demand, the price may fall.
Third, the purchase quantity is also related to the price. Bulk purchases, merchants often give it at a preferential price, the larger the quantity, the better the price. Retail prices may be higher.
Fourth, purity has a deep impact on the price. For high purity, the preparation is difficult, the cost is high, and the price is high; for low purity, the use or limited, and the price is relatively low.
According to past market conditions and the price trend of similar chemicals, if it is purchased in small quantities for laboratories, the price of higher purity may range from tens of yuan to hundreds of yuan per gram. If it is purchased in large quantities for industry, the price per ton may range from tens of thousands to hundreds of thousands of yuan depending on the quantity. However, this is only a rough guess. The actual price needs to be consulted with the relevant chemical raw material suppliers in detail, subject to the real-time market quotation.

5-Bromo-1,3-difluoro-2- (trifluoromethoxy) benzene is also an organic compound. Its storage conditions are of paramount importance and are related to the stability and safety of this compound.
This compound should be stored in a cool and well-ventilated place. Covering a cool environment can reduce its chemical reaction rate due to excessive temperature and avoid the risk of decomposition and deterioration. Well-ventilated, it can disperse volatile gases that may escape in time to avoid the risk of accumulation and explosion.
Furthermore, storage must be kept away from fire and heat sources. Fire and heat sources can cause a sudden rise in temperature, which greatly increases the molecular activity of the compound and triggers uncontrollable reactions, such as combustion and explosion. Therefore, fireworks must be strictly prohibited around, and electrical equipment should also have explosion-proof functions.
The compound must be stored separately from oxidizing agents, acids, and bases, and should not be mixed. Due to its active chemical properties, it is easy to react with various chemicals. If it encounters an oxidizing agent, it may cause a violent oxidation reaction; if it interacts with an acid or alkali, it may change the molecular structure, damage its quality, and even lead to safety accidents.
Storage containers should also be carefully selected. Corrosion-resistant materials such as glass, specific plastics, or metal containers must be used to ensure that the containers are well sealed and free from leakage. Because the compound is either corrosive or volatile, it is easy to lose if it is not properly sealed, and the volatile gas can cause environmental pollution and human harm.
When handling this material, it must also be handled lightly to prevent damage to the packaging and containers. A little carelessness can cause package rupture and compound leakage, which is especially difficult to deal with, and the leakage may endanger the environment and human health.
In summary, following the above storage conditions can ensure the quality and safety of 5-bromo-1,3-difluoro-2- (trifluoromethoxy) benzene, which is beneficial for production, scientific research and other purposes.