As a leading 5-Bromo-1,3-Difluoro-2-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 5-Bromo-1, 3-Difluoro-2-Iodobenzene?
5-Bromo-1,3-difluoro-2-iodobenzene is one of the organic compounds. It has a wide range of uses and is a key intermediate in the field of organic synthesis.
First, in the field of medicinal chemistry, it can be used to prepare drug molecules with specific biological activities. Due to the presence of halogen atoms in its structure, other functional groups can be introduced through many organic reactions, such as nucleophilic substitution reactions, to construct drug precursors with diverse structures, laying the foundation for the development of new drugs.
Second, in the field of materials science, it can be integrated into the structure of polymer materials through specific chemical reactions. Due to its halogen atom properties, it may endow materials with unique electrical and optical properties, such as improving the conductivity and fluorescence properties of materials, so it also has potential application value in optoelectronic materials.
Furthermore, in the field of fine chemicals, it is often used to synthesize fine chemicals with special structures. For example, as a starting material, high-value added flavors, dyes and other products are synthesized through multi-step reactions to help improve the quality and performance of fine chemical products.
Overall, 5-bromo-1,3-difluoro-2-iodobenzene plays an important role in many fields due to its unique structure, providing key support for the development of organic synthetic chemistry and the progress of related industries.
What are the physical properties of 5-Bromo-1 3-Difluoro-2-Iodobenzene?
5-Bromo-1,3-difluoro-2-iodobenzene is one of the organic compounds. Its physical properties are quite important, and I will describe them in detail today.
First of all, its appearance, under room temperature and pressure, this substance is mostly colorless to light yellow liquid, clear and transparent, and looks quite fluid. It has a special smell, although not pungent and unpleasant, it is also different from ordinary odorless things, with a slightly unique smell.
When it comes to melting point, the melting point of 5-bromo-1,3-difluoro-2-iodobenzene is relatively low, between -10 ° C and 10 ° C. This property makes the substance easy to appear liquid in an environment slightly higher than normal temperature without excessive temperature changes.
In terms of boiling point, it is between 180 ° C and 200 ° C. This boiling point value shows that in order to change from liquid to gaseous state, a considerable amount of heat needs to be applied to allow the molecules to obtain enough energy to break free from each other's forces.
Solubility is also one of the key properties. This compound exhibits good solubility in organic solvents, such as common ethanol, ether, dichloromethane, etc. However, in water, its solubility is poor. Due to the molecular structure of the substance, the interaction between it and water molecules is weak, and it is difficult to dissolve in the water phase with strong polarity.
On the density, 5-bromo-1,3-difluoro-2-iodobenzene is heavier than water, and its density is about 2.3-2.5 g/cm ³. This characteristic makes it sink to the bottom when mixed with water. This phenomenon is of great reference value in related chemical operations and studies.
In addition, the stability of 5-bromo-1,3-difluoro-2-iodobenzene is acceptable under conventional conditions. However, it contains bromine, fluorine, iodine, and other halogen atoms. Under specific chemical reaction conditions, halogen atoms can participate in many reactions. Therefore, when storing and using them, one should also pay attention to their environment and conditions to prevent unnecessary reactions from occurring.
What is the synthesis method of 5-Bromo-1,3-Difluoro-2-Iodobenzene
To prepare 5-bromo-1,3-difluoro-2-iodobenzene, you can do it by the following method. First, take a suitable aromatic compound, such as 1,3-difluorobenzene, as the starting material for the reaction.
The first step is to react 1,3-difluorobenzene with a brominating reagent. This brominating reagent can be selected from bromine (Br _ 2) and accompanied by a suitable catalyst, such as iron powder (Fe) or iron tribromide (FeBr _ 3). Under suitable reaction conditions, such as heating and in an inert solvent, bromine atoms will selectively replace hydrogen atoms at specific positions on the benzene ring to generate 5-bromo-1,3-difluorobenzene. This step is based on the electrophilic substitution reaction of the benzene ring. Bromine forms an electrophilic reagent under the action of a catalyst, attacking the higher electron cloud density of the benzene ring.
In the next step, 5-bromo-1,3-difluorobenzene is reacted with an iodizing reagent. The iodizing reagent can be iodine (I _ 2) and an appropriate oxidizing agent such as hydrogen peroxide (H _ 2O _ 2) or nitric acid (HNO _ 3) is added. In a suitable reaction environment, such as a specific temperature and solvent system, iodine atoms will replace the hydrogen atoms at the target position on the benzene ring to obtain 5-bromo-1,3-difluoro-2-iodobenzene. This step of the reaction is also an electrophilic substitution process. The role of the oxidant is to promote the formation of electrophilic active species of iodine to realize the substitution of iodine to the benzene ring.
During the reaction process, it is necessary to pay attention to the precise control of the reaction conditions at each step, such as temperature, reaction time, reagent dosage, etc., in order to obtain higher yield and purity. And after each step of the reaction, it often needs to be separated and purified, such as extraction, distillation, recrystallization and other means to remove by-products and unreacted raw materials, and finally obtain pure 5-bromo-1,3-difluoro-2-iodobenzene.
What is the market price of 5-Bromo-1,3-Difluoro-2-Iodobenzene
I have not obtained the market price of 5 - Bromo - 1,3 - Difluoro - 2 - Iodobenzene. The market situation is changing rapidly, and the price often varies according to the source, quality, purchase quantity, time and place. To know the exact price, you should consult the chemical raw material supplier, the chemical trading platform, or visit the relevant industry exhibition. At the chemical raw material supplier, he can tell the exact price according to the real-time inventory and market supply and demand. On the chemical trading platform, there are also quotations from various companies, which can be compared. In the industry exhibition, you can negotiate with the industry, and you may get preferential prices and opportunities for cooperation. Therefore, in order to obtain the market price of this product, you need to explore and compare it in detail to get a suitable price.
5-Bromo-1, 3-Difluoro-2-Iodobenzene What are the precautions in storage and transportation?
5-Bromo-1,3-difluoro-2-iodobenzene is an organic compound. When storing and transporting, many things must be paid attention to.
First words storage. This compound is more sensitive to light and air, so it should be stored in a cool, dry and well-ventilated place, away from heat sources and open flames to prevent fire. Be sure to use dark packaging, such as dark glass bottles, to prevent light intrusion and cause decomposition. Because of its certain chemical activity, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed, otherwise it may cause violent chemical reactions. At the same time, the storage area should be equipped with suitable containment materials to prevent leakage accidents from being dealt with in time.
Second talk about transportation. During transportation, the packaging must be sturdy to ensure that it will not be damaged or leaked under normal transportation conditions. It needs to be implemented in accordance with the relevant regulations on the transportation of hazardous chemicals, and the transportation vehicles should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. Transportation personnel should also be professionally trained to be familiar with the characteristics of the compound and emergency treatment methods. During transportation, avoid high temperatures and bumpy road sections to prevent material leakage caused by damage to the packaging. In the event of leakage, the surrounding people should be evacuated immediately. After taking protective measures, clean up and dispose of it in time to prevent environmental pollution.
Only in this way can the storage and transportation of 5-bromo-1,3-difluoro-2-iodobenzene be ensured to the greatest extent and accidents can be avoided.