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5-Bromo-1,2,3-Trifluorobenzene

5-Bromo-1,2,3-Trifluorobenzene

Hongda Chemical

Specifications

HS Code

234407

Chemical Formula C6H2BrF3
Molecular Weight 225.0
Appearance Liquid (usually)
Boiling Point 143 - 145 °C
Density Data may vary, around 1.7 - 1.8 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ether, dichloromethane
Flash Point Data may vary, typically flammable liquid
Vapor Pressure Depends on temperature, relatively low for a liquid at ambient

As an accredited 5-Bromo-1,2,3-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 5 - bromo - 1,2,3 - trifluorobenzene: Packed in 1 - liter bottles, quantity 100 bottles.
Storage 5 - bromo - 1,2,3 - trifluorobenzene should be stored in a cool, well - ventilated area away from heat sources and ignition points. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions. Label the storage clearly for easy identification and safety handling.
Shipping 5 - bromo - 1,2,3 - trifluorobenzene is a chemical. Ship it in well - sealed, corrosion - resistant containers. Follow hazardous chemical shipping regulations, ensuring proper labeling and handling to prevent spills and ensure safety during transit.
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5-Bromo-1,2,3-Trifluorobenzene 5-Bromo-1,2,3-Trifluorobenzene
General Information
Historical Development
5 - Bromo - 1,2,3 - Trifluorobenzene is also an organic compound. Its traces can be traced back to the past. At the beginning, organic chemistry has not been around for a long time, and various compounds have yet to be explored. At that time, scholars were in the laboratory, carefully studying, hoping to reveal the nature of new substances.
With the passage of time, chemical technology has become more and more exquisite. The method of analysis is becoming more accurate, and the technique of synthesis is also becoming more and more mature. 5 - Bromo - 1,2,3 - The synthesis path of Trifluorobenzene has been repeatedly pondered by scholars and finally optimized. In the past, it may have required complicated steps and the yield was not high. However, today is different from the past. The new synthesis method makes its preparation more convenient and efficient.
This compound is gradually being used in the fields of materials science and drug development. From ancient times to the present, from unfamiliar and new things to widely known and increasingly used, the development of 5-Bromo-1,2,3-Trifluorobenzene is also reflecting the progress of chemistry.
Product Overview
5-Bromo-1,2,3-trifluorobenzene is a key raw material for organic synthesis. Its color is pure and pure, and its shape is like a clear liquid, with unique physicochemical properties.
This product has a moderate boiling point and gasifies into steam at a specific temperature. Its melting point is precise, which is the key to temperature control during synthesis. In the stage of organic reactions, it is often a powerful tool for introducing bromine and fluorine groups. With its unique structure, it can cleverly combine with various reagents, and react with nucleophilic substitution, coupling, etc., to breed many exquisite organic products.
In the process of scientific research, chemists rely on it as a brick and stone to build a complex molecular structure. In the industrial field, it is also the cornerstone for the preparation of high-end materials and special drugs. In the field of organic chemistry, it is like a shining star, illuminating the long journey of synthetic exploration, helping the birth of many new compounds, and promoting the continuous progress of chemical technology.
Physical & Chemical Properties
5 - Bromo - 1,2,3 - Trifluorobenzene is an organic compound. Its physical properties are mostly colorless to light yellow liquid at room temperature, with a special odor. The boiling point is suitable, and it can be gasified into steam at a certain temperature, which is convenient for separation and purification. The density is different from that of water, and it will be in a specific position in a specific reaction system, which affects the reaction process.
Chemically, bromine atoms and fluorine atoms in this compound are highly active. Bromine atoms are prone to substitution reactions. Under the action of nucleophiles, they can be replaced by other groups to derive a variety of compounds. Fluorine atoms have strong electronegativity, which can enhance molecular stability, and affect the distribution of surrounding atomic electron clouds, so that the density of benzene ring electron clouds changes, which affects its electrophilic substitution reaction activity. Due to its many characteristics, it is widely used in the field of organic synthesis.
Technical Specifications & Labeling
5-Bromo-1,2,3-trifluorobenzene is also a chemical substance. Its process specifications and identification (product parameters) are related to the preparation method and characteristic identification. The preparation of this 5-bromo-1,2,3-trifluorobenzene requires a rigorous process. The choice of raw materials must be pure; the temperature and pressure of the reaction should be precisely controlled. The reaction process, or after several steps, all steps comply with the laws of chemistry.
In terms of identification, the name is "5-bromo-1,2,3-trifluorobenzene", and the molecular formula, molecular weight and other parameters are also important for identification. And its physical and chemical properties, such as color, taste, melting and boiling point, are detailed in the label, so that the application can be appraised, so that the process specification and label of 5-bromo-1,2,3-trifluorobenzene can be obtained.
Preparation Method
In order to prepare 5-Bromo-1,2,3-Trifluorobenzene, the raw materials and production process, reaction steps and catalytic mechanism are the key.
In the selection of raw materials, it is appropriate to use compounds containing fluorine and bromine. Starting with fluorobenzene, select suitable brominating reagents, such as bromine or brominating agent, and the ratio of the two is precisely prepared according to the reaction requirements.
In the production process, the reaction environment needs to be carefully regulated. In a suitable organic solvent, ensure that the reaction system is uniform. The control of temperature and pressure is extremely important. The temperature rise or fall should be gradual to fit the reaction mechanism.
In the reaction step, the fluorobenzene is first met with the brominating reagent under specific conditions to initiate a substitution reaction. The reaction process is closely monitored and the degree of reaction is controlled by suitable detection methods, such as chromatographic analysis.
In terms of catalytic mechanism, the selection of high-efficiency catalysts can accelerate the reaction rate and improve the purity of the product. The amount and activity of the catalyst need to be carefully considered to make it work best in the reaction, so that 5-Bromo-1,2,3-Trifluorobenzene can be efficiently prepared.
Chemical Reactions & Modifications
5 - Bromo - 1, 2, 3 - Trifluorobenzene is an important intermediate in organic synthesis. Its chemical reaction and modification are related to the progress of many fields.
Looking at its chemical reaction, it often involves nucleophilic substitution and the like. Under appropriate conditions, bromine atoms can be replaced by nucleophilic reagents, such as reacting with nitrogen and oxygen nucleophiles, derived a variety of compounds, and expanded chemical space.
When talking about modification, different groups can be introduced to improve its physical and chemical properties. Or increase its solubility, or modify its reactivity to suit specific needs. The modification process requires precise control of reaction conditions, such as temperature, catalyst type and dosage, in order to obtain the ideal product.
In the field of chemical research, the reaction and modification of 5-Bromo-1,2,3-Trifluorobenzene are studied, which continues to promote the progress of organic synthetic chemistry and pave a broader path for new material research and development, drug creation and other fields.
Synonyms & Product Names
5-Bromo-1,2,3-trifluorobenzene is also a chemical product. Although their names are different, they all refer to this thing. Ancient maester, in the name of a thing, often means it, or because of its shape, or because of its properties, or because of its use. Today's 5-bromo-1,2,3-trifluorobenzene, also known by him, is synonymous with the name of a commodity.
This substance is widely used in the industry of chemistry. Although the names are different, their quality is the same. In the past, it was used to govern chemistry, and the properties of the material were carefully examined, and the name was also prudent. Today's 5-bromo-1,2,3-trifluorobenzene, although named or miscellaneous, are all the same thing, and the industry should know its meaning and not be confused by different names.
Safety & Operational Standards
5 - Bromo - 1,2,3 - Trifluorobenzene Safety and Operating Specifications
5 - Bromo - 1,2,3 - Trifluorobenzene is a common chemical in chemical research. When using this chemical, many safety and operating practices must be strictly followed.
#1. Storage Safety
This chemical should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources and avoid direct sunlight. Because of its certain chemical activity, if the storage environment is not good, it is easy to cause deterioration or other chemical reactions, thus endangering safety. The storage area must be separated from oxidants, acids, bases, etc., and must not be mixed to prevent dangerous chemical reactions.
#2. Operating Specifications
When operating, the experimenter must wear appropriate protective equipment. Wear chemical protective clothing to effectively prevent skin contact with the chemical; wear protective gloves, the material must be able to resist the erosion of 5 - Bromo - 1,2,3 - Trifluorobenzene; goggles or face masks are also indispensable to protect the eyes from possible splashing chemicals.
It is extremely important to operate in a fume hood. The fume hood can discharge harmful gases that may be volatilized during the operation in time, reducing the risk of inhaling toxic substances by the experimenter. The operation process should be rigorous and meticulous to avoid the leakage of the chemical. If a leak occurs accidentally, emergency measures should be taken immediately. First, quickly evacuate personnel from the leaked contaminated area to a safe area, and quarantine them, strictly restricting access. Emergency personnel need to wear self-contained positive pressure breathing apparatus and chemical protective clothing, and do not come into direct contact with leaks. In the case of small leaks, it can be absorbed by sand, vermiculite or other inert materials; in the case of large leaks, it is necessary to build embankments or dig pits to contain them, cover them with foam to reduce steam disasters, and then transfer them to a tank truck or special collector for recycling or transportation to a waste treatment site for disposal.

#3. Emergency treatment
If the skin comes into contact with 5-Bromo-1,2,3-Trifluorobenzene, the contaminated clothing should be removed immediately, rinsed with a large amount of flowing water for at least 15 minutes, and then seek medical attention in time. If eye contact, immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention as soon as possible. If inhaled accidentally, quickly leave the scene to a fresh air place, keep the respiratory tract unobstructed, such as breathing difficulties, give oxygen, if breathing stops, immediately perform artificial respiration and seek medical attention.
5 - Bromo - 1,2,3 - Trifluorobenzene safety and operating standards are of paramount importance, related to the safety of the experimental personnel and the smooth progress of the experiment, must not be taken lightly.
Application Area
5-Bromo-1,2,3-trifluorobenzene is also an organic compound. It has a wide range of uses and can be used as a key raw material for the synthesis of special drugs in the field of medicinal chemistry. With its special chemical structure, it can react ingeniously with other substances to form an ingredient with unique pharmacological activity, or it can be used as a new anti-cancer drug or a cure for nervous system diseases.
In the field of materials science, it also has its uses. It can participate in the preparation of polymer materials with special properties, so that the materials have better heat resistance and chemical corrosion resistance. It has potential applications in high-end fields such as aerospace and electronic devices.
In the fine chemical industry, 5-bromo-1,2,3-trifluorobenzene can be used as the starting material for the synthesis of special dyes and fragrances. After a series of reactions, the product is given a unique color and fragrance, increasing its commodity value.
Research & Development
We are dedicated to the research and development of 5 - Bromo - 1,2,3 - Trifluorobenzene. This compound has unique characteristics and great potential in many fields.
Initially explore its synthesis method. After repeated experiments and studying ancient methods and new techniques, strive to optimize the path and improve the yield and purity. In the experiment, fine regulation of reaction conditions, such as temperature, pressure, and catalyst dosage, are carefully considered.
Next, explore its application scope. In pharmaceutical chemistry, it may be used as a key intermediate to help the development of innovative drugs; in materials science, it is also expected to give novel properties to materials.
Looking to the future, we will continue to refine the synthesis process to reduce costs and increase efficiency. At the same time, expand the application field and cooperate with all walks of life to make 5 - Bromo - 1, 2, 3 - Trifluorobenzene play a greater value and contribute to scientific research progress and industrial development.
Toxicity Research
Today, there are chemical substances, named 5 - Bromo - 1, 2, 3 - Trifluorobenzene, and our generation takes the study of toxicants as our business to investigate their properties in detail. The toxicity of this substance is related to the safety of living beings, and it is necessary to be careful.
Investigate its properties in detail, or it may be exposed to the body through respiration or skin contact. In experiments, animals are observed to be affected by this substance, and their behavior is abnormal, or they may be tired, or their physiological functions may change slightly. Although it is only a preliminary investigation, its potential toxicity has already emerged.
We should continue to conduct in-depth research with caution to identify its exact toxicity and long-term effects on the environment and biology. In this way, it is the right way to protect all living things and ensure the tranquility of the environment, and it is also the important responsibility of chemical researchers.
Future Prospects
5 - Bromo - 1,2,3 - Trifluorobenzene, organic compounds are also. Looking at it today, although in the field of chemical research, there have been various explorations and applications. However, I look to the future, and its prospects are vast.
In the process of synthetic chemistry, or with its unique structure, it can become a key building block for new complex organic molecules. Through exquisite design of reactions, it is possible to construct a variety of functional materials, such as devices for efficient photoelectric conversion, to help innovation in the field of energy.
In the field of medicinal chemistry, it is expected to use its characteristics to develop specific new drugs. It may be able to precisely regulate biological activities and open up new paths to overcome difficult diseases.
Furthermore, with the advance of science and technology, the analysis and testing methods should also be improved, and the analysis of its purity and impurities will be more subtle, making the production and application more accurate. This 5 - Bromo - 1,2,3 - Trifluorobenzene will shine in the future and add great impetus to the development of various fields of chemistry.
Where to Buy 5-Bromo-1,2,3-Trifluorobenzene in China?
As a trusted 5-Bromo-1,2,3-Trifluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 5-Bromo-1,2,3-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 5-bromo-1,2,3-trifluorobenzene?
5% - 1, 2, 3 - The main users of the Three Rivers Hu are for irrigation, irrigation and transportation.
Those who use water, the life of the food is very important for human survival. 5% - 1, 2, 3 - The water of the Three Rivers Hu, which is clear and sweet, provides the basic water source for the people around the world. The people feed on the sky, and the water is the foundation of survival. The water of the Three Rivers Hu, which is nourishing and growing, has great merits.
Furthermore, the use of irrigation cannot be ignored. The surrounding fertile fields are thousands of miles away, and the water of the Three Rivers Hu can be nourished. The husband diverts water to irrigate the fields, so that the five crops can be climbed and the mulberry can flourish. The crops in the fields can get water, and the water can be made into a whole. The people provide a source of food and ensure the stability of people's livelihood.
And it is also an important function in the way of transportation. Sanjiang and Hu are connected to many places, and the convenience of water is conducive to the circulation of goods. Boats go to other places, and they can be used to transport goods, and the city can be connected. Promote the prosperity of commerce. Soil specialties, handicrafts, etc. from all over the world can be used to transfer water to other places, and they can be interconnected and promoted.
Of course, 5% - 1,2,3 - Sanjiang and Hu water play an important role in the use, irrigation, and consumption. It is the foundation for the survival and development of the people, and it is cherished and protected.
What are the physical properties of 5-bromo-1,2,3-trifluorobenzene?
1,2,3-Tribromobenzene is the product obtained by the reaction of phosphorus pentabromide with benzene under specific conditions. Its physical properties are quite characteristic, as detailed below:
1. ** Appearance **: Under normal conditions, 1,2,3-tribromobenzene appears as a white to light yellow crystalline powder. This color and shape are like "jade dust like silver dust, flashing with a faint yellowish luster, like the soft afterglow shining on the fine powder at dusk". In the sunlight, it resembles delicate golden sand and exudes a unique light.
2. ** Melting point **: Its melting point is between 121-124 ° C. In this temperature range, 1,2,3-tribromobenzene is like ice and snow in spring, gradually melting from the solid state to the liquid state, just like "ice and snow melt, the original solid form gradually softens and flows in the warm embrace", from a stable solid state to a flexible liquid state, realizing the transformation of the material state.
3. ** Boiling point **: The boiling point is about 314 ° C. When the temperature rises to this point, 1,2,3-tribromobenzene is like a feathered bird, breaking free from the liquid state and turning into a gaseous state. "Just like water vapor evaporates, curling up, and with the help of high temperature, the sublimation from liquid state to gaseous state is completed." The bonds between molecules are broken at high temperature and float freely in space.
4. ** Solubility **: 1,2,3-tribromobenzene is insoluble in water, but it is easily soluble in organic solvents such as ethanol, ether, chloroform, etc. In water, it is like "an independent fairy, not fused with water, quietly suspended or precipitated in the bottom of the water", while in organic solvents, it is like a fish in water, rapidly diffuses and dissolves, and fuses with the solvent, "just like salt entering the water, instantaneously invisible, evenly dispersed in it".
5. ** Density **: The density is larger than that of water, and when placed in water, it will be like "heavy stones, sinking straight to the bottom". Because of its tight molecular structure, the density is greater than that of water, occupying the lower layer in the liquid layer.
What are the synthesis methods of 5-bromo-1,2,3-trifluorobenzene?
The synthesis of 5-hydroxyl-1,2,3-triazinone has attracted much attention in the field of organic synthesis. To obtain this compound, the following paths can be used:
First, a compound containing hydroxyl groups interacts with a specific nitrogen source under suitable reaction conditions. For example, using a hydroxyl aromatic hydrocarbon as the starting material, first with a nitrogen-containing active reagent, in the catalytic environment of an acid or base, through nucleophilic substitution or addition reaction, the basic structure of nitrogen-containing is initially constructed. Then, by means of oxidation or cyclization steps, the atomic rearrangement and bonding in the molecule are promoted to finally form the structure of 5-hydroxyl-1,2,3-triazinone. In this process, the precise control of reaction conditions is crucial, such as temperature, pH, reaction time, etc., which will have a significant impact on the yield and purity of the product.
Second, the method of functional group transformation can be started from compounds with similar structures. For example, select a derivative with a triazine ring structure, and gradually convert the existing functional groups on it into hydroxyl groups through specific chemical means. This conversion process involves various reaction steps such as reduction, hydrolysis, and oxidation. Each step requires following the reaction mechanism, carefully selecting reagents and conditions to ensure the efficiency and selectivity of the reaction, so as to successfully achieve the synthesis of 5-hydroxy- 1,2,3-triazinone.
Third, use the strategy of cyclization and condensation. Take appropriate bifunctional or polyfunctional compounds and make them undergo intramolecular cyclization and condensation reactions under specific conditions. Such compounds need to have suitable spatial structures and reactivity in order to effectively form the target triazinone ring system in a suitable catalyst and reaction environment, and introduce hydroxyl groups at specific positions. This method requires thorough consideration of the structural design of the reactants, and in-depth investigation of the stereochemistry and electronic effects of the reaction to achieve precise synthesis of the target product.
There are many methods for the synthesis of 5-hydroxy- 1,2,3-triazinone, but they all require organic synthesizers to be familiar with various reaction mechanisms and to be able to flexibly adjust the reaction conditions in order to achieve the purpose of efficient and high-purity synthesis.
What are the precautions for storing and transporting 5-bromo-1,2,3-trifluorobenzene?
5% -1,2,3-Sanjiang Hu is in the process of storage, and pay attention to general matters, so as to ensure the safety of its quantity.
First, where it is stored, it will be dry and clear. This material is pleasant and refreshing. If it is in a tidal place, it is easy to be damp, and it is easy to be damp. And it is well-passed, which can avoid the breeding of fungi and the invasion of beetles.
Second, the degree of control should also be controlled. It should be stored in a cool place to avoid high temperature. Under high temperature, the active ingredients in 5% -1,2,3-Sanjiang Hu are either dissipated or modified, so that their effect is great. Generally speaking, the degree of storage should not exceed 25 degrees Celsius.
Third, it is necessary to store it in a solid container, and it is made of moisture-proof materials to prevent bumps and collisions on the way, causing the material to break, and also preventing the intrusion of the outside world. And it is necessary to keep it clean, and it is not allowed to smell or toxic and harmful substances with it, so as to avoid the material being contaminated.
Fourth, pay attention to the storage period. 5% - 1,2,3 - Sanjiang Hu has a certain shelf life, but it needs to be checked regularly, and its durability is weak. Therefore, it is necessary to determine whether it is available or not according to the quality of the material and the phase.
Therefore, 5% -1,2,3-Sanjiang Hu should not be ignored in such things as storage, dryness, appropriate degree, packaging, and attention period, so as to ensure that its useful value is not low.
What is the market price of 5-bromo-1,2,3-trifluorobenzene?
Today, there are five rivers and one, two, and three rivers of Bupleurum, and the price of their market is related to various reasons.
The price of medicinal materials depends first on the place of origin. In the land of five rivers, the water and soil climate are different, and the quality of Bupleurum produced is different, and the price is also different. The fertile soil is fertile, and the medicinal power is mellow, and the price may be high; the production of barren land is slightly inferior in quality, but the price is slightly cheaper. The same is true in the first, second, and three rivers. The water and soil of the river are suitable, and the price of Bupleurum produced is the best.
Furthermore, the change of years has a great impact on the price of Bupleurum. In the prime of life, the production of Bupleurum is abundant, the market is full of goods, and the price tends to be flat; in the event of a bad year, natural disasters are raging, the output is sharply reduced, and the goods are scarce and expensive.
The method of harvesting is also the key. Proficient in the time of harvesting, in line with the regulations of processing, the quality of the medicine is good, and the price is considerable; if the harvesting is inappropriate, the quality of the medicine is damaged, and the price also falls.
The supply and demand of the city, especially the price. Doctors use Bupleurum frequently, and patients have a lot of demand, but the market is short of goods, and the price will soar; if the demand is low, the goods are in the market, and the price will decline.
There are merchants, which A good operator can judge the situation, control the flow of goods, and the price may be stable; if merchants hoard and drive up prices, the price will be inflated.
In summary, the market prices of Wuhe and Yiyi, Eryi, and Sanchuan Bupleurum are intertwined by factors such as origin, age, procurement, supply and demand, and business management. It is difficult to generalize. It is necessary to carefully observe the situation at that time to know the price.