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4-(Trifluoromethyl)Nitrobenzene

4-(Trifluoromethyl)Nitrobenzene

Hongda Chemical

Specifications

HS Code

503454

Chemical Formula C7H4F3NO2
Molar Mass 191.107 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 202 - 204 °C
Melting Point −27 °C
Density 1.437 g/cm³
Flash Point 87 °C
Solubility In Water Insoluble
Vapor Pressure 0.133 kPa (25 °C)
Refractive Index 1.470 (20 °C)

As an accredited 4-(Trifluoromethyl)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4-(trifluoromethyl)nitrobenzene packaged in a sealed, corrosion - resistant bottle.
Storage 4-(Trifluoromethyl)nitrobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container to prevent vapor release. Store it separately from oxidizing agents, reducing agents, and bases, as it may react with them. This storage approach helps maintain its stability and reduces safety risks.
Shipping 4-(Trifluoromethyl)nitrobenzene is shipped in accordance with strict chemical regulations. It's typically in sealed, corrosion - resistant containers, safeguarded during transit to prevent spills and ensure safe delivery to the destination.
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4-(Trifluoromethyl)Nitrobenzene 4-(Trifluoromethyl)Nitrobenzene
General Information
Historical Development
The chemical industry is changing with each passing day, and the research of substances is gradually becoming more and more refined. Today there is 4 - (trifluoromethyl) nitrobenzene, which has its own unique traces in the chemical industry of the past.
At the beginning, researchers explored in the field of chemistry and strived for new things. At that time, technology was not as prosperous as it is today, and the research of this substance was difficult. However, the researchers had great ambitions and worked tirelessly.
After years of work, they gradually obtained the method of preparation. The initial method may be complicated and inefficient, but every step is the foundation for future generations. With the passage of time, the technology has become more and more mature, the preparation has become more and more exquisite, and the yield has also increased.
Looking at its development path, it is actually the hard work of the researchers. From the initial exploration to the gradual formation of a system, 4- (trifluoromethyl) nitrobenzene has gradually developed its use in the field of chemical industry, adding bricks and mortar to many industries and adding a touch of brilliance to the research of chemistry.
Product Overview
4- (trifluoromethyl) nitrobenzene is an organic compound. It may be a colorless to light yellow liquid with a special odor. This substance has a wide range of uses in the chemical industry and can be used as a raw material for the synthesis of many fine chemicals.
The synthesis method is often obtained by nitrification of aromatic hydrocarbons containing trifluoromethyl. During the reaction, it is necessary to pay attention to the control of the reaction conditions, such as temperature, reagent ratio, etc., to increase the purity and yield of the product.
4- (trifluoromethyl) nitrobenzene has unique properties. It has certain chemical activity and stability due to the presence of trifluoromethyl and nitro groups. In organic synthesis, various conversion reactions can be carried out by virtue of the characteristics of its functional groups to obtain derivatives with different structures.
However, this substance also has certain dangers. When using it, follow safety procedures and take appropriate protective measures to avoid harm to the human body and the environment.
Physical & Chemical Properties
4- (trifluoromethyl) nitrobenzene is also an organic compound. Its physical and chemical properties can be investigated.
Under normal temperature, it is a colorless to light yellow liquid with a special odor. The boiling point is about a certain value, which varies slightly depending on the measurement environment. Its density is heavier than that of water, and it is insoluble in water, but soluble in organic solvents such as alcohols and ethers.
In terms of its chemical properties, it is active because it contains nitro and trifluoromethyl groups. Nitro groups are strongly oxidizing, and trifluoromethyl groups change the distribution of molecular electron clouds. In case of reducing agents, nitro groups can be reduced, and if appropriate reagents are used, they can be reduced to amino groups. And it can participate in the nucleophilic substitution reaction. Due to the electron absorption of trifluoromethyl, the electron cloud density of the benzene ring decreases, which is favorable for the attack of nucleophilic reagents. The properties of this compound are widely used in the field of organic synthesis, and it can be used as an intermediate to produce a variety of fine chemicals.
Technical Specifications & Labeling
There are technical regulations and identification (product parameters) for the production of 4- (trifluoromethyl) nitrobenzene, which is a priority. To make this product, you should prepare all kinds of raw materials in advance to check whether it is pure or not. When handling the equipment, you must also be clean and intact to ensure that everything goes smoothly.
In the reactor, put the raw materials in a certain ratio, control its temperature, and check the heat. Do not make mistakes. After the reaction is completed, after separation and purification, the refined product is obtained.
Look at the finished product, the color is pure, the taste is correct, and the parameters, such as melting point, boiling point, and purity, must be in line with the specified standard. On the logo, specify the product name, ingredients, specifications, and origin to make it clear to the viewer. In this way, the 4- (trifluoromethyl) nitrobenzene products of Fang De Good, technical procedures and labels are the foundation of quality and cannot be ignored.
Preparation Method
The preparation method of 4- (trifluoromethyl) nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often started with benzene compounds containing trifluoromethyl, such as trifluoromethylbenzene. The target product can be obtained by nitration reaction.
In the reaction step, in a suitable reaction vessel, trifluoromethylbenzene and a suitable nitrifying agent, such as mixed acid (mixing of concentrated sulfuric acid and concentrated nitric acid), are added. Control of temperature and reaction time is the key. If the temperature is too high, it is easy to cause side reactions, and if it is too low, the reaction rate is slow.
In the catalytic mechanism, concentrated sulfuric acid acts as a catalyst for this reaction, enhancing the electrophilicity of nitric acid and promoting the electrophilic substitution reaction with tri
The production process needs to pay attention to the precise control of the reaction conditions, and the separation and purification of the product after the reaction are also important. High purity 4- (trifluoromethyl) nitrobenzene is obtained by distillation, extraction and other means. In this way, a good method for preparing this compound is obtained.
Chemical Reactions & Modifications
The chemical reaction and modification of Fu 4- (trifluoromethyl) nitrobenzene are related to the gist of chemical industry. In the past, the preparation of this compound often had complicated reaction paths. The initial reaction conditions were harsh, the yield was not ideal, and the side reactions were frequent, and impurities were clumped.
Guanfu chemical modification aims to optimize its characteristics. Or introduce new radicals to change its activity; or adjust the reaction conditions to obtain better output. After various explorations, improved methods gradually emerged. The trial of the new catalyst enabled the reaction to proceed in a milder environment, the yield was improved, and the side reactions were suppressed.
Furthermore, the in-depth study of the reaction mechanism paved the way for modification. Clarifying the relationship between the reaction steps and precise regulation make the preparation of 4- (trifluoromethyl) nitrobenzene more efficient and pure, and the application prospect in chemical production is brighter. It also adds a good example to chemical research and advances in chemical technology.
Synonyms & Product Names
Today, there is a product named 4- (trifluoromethyl) nitrobenzene. The alias of this product is also known as it. It is a genus of chemical industry and has a wide range of uses.
Looking at its name, trifluoromethyl is combined with nitro in the benzene ring. It has specific properties and is an important chemical raw material. In the process of synthesis, it is often the starting point, leading to reactions and producing a variety of products.
The name of the trade name, the industry has its own say. However, regardless of the alias or trade name, it refers to this 4- (trifluoromethyl) nitrobenzene. It plays a significant role in the field of chemical industry, and is valued by researchers. It is important to explore its properties and study its uses. It is hoped to expand its path, increase its efficiency, and help the industry.
Safety & Operational Standards
"Code of Safety and Operation of 4- (Trifluoromethyl) Nitrobenzene"
Fu4- (Trifluoromethyl) Nitrobenzene is a common substance in chemical research. In terms of experimental operation and storage, safety regulations are of paramount importance.
First of all, it is about storage. Keep this substance in a cool, dry and well-ventilated place. Avoid open fires and hot topics to avoid the risk of explosion. The container must be sealed to prevent leakage and cause environmental pollution and personal hazards.
When operating, all kinds of protection are essential. The operator wears protective clothing, protective gloves and goggles to prevent the substance from contacting the skin and eyes. If it is operated in a fume hood, it can effectively disperse harmful gases, keep the air fresh, and protect the health of the operator.
Furthermore, during use, measure accurately and follow the standard steps. Do not mix this substance with incompatible substances to prevent violent reactions. In the event of a leak, take emergency measures immediately. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be contained, properly handled, and not allowed to disperse.
When disposing of waste, relevant regulations should also be followed. It should not be discarded at will, and should be handled by a professional organization according to the prescribed process to ensure environmental safety.
In short, in the research and application of 4- (trifluoromethyl) nitrobenzene, strict adherence to safety and operating standards can avoid disasters, promote the smooth progress of scientific research, and ensure the safety of personnel and the environment.
Application Area
Today there are chemical substances, known as 4- (trifluoromethyl) nitrobenzene. Its application field is quite wide. In the field of pharmaceutical chemistry, this compound is often an important raw material to help the development of new drugs. Because of its special structure, it can make drug molecules have unique activity, which can be used to fight various diseases, such as the treatment of some difficult and miscellaneous diseases, and has potential power.
In the field of materials science, it also has important uses. It can participate in the preparation of high-performance materials through specific processes. It imparts special properties to the material, such as enhancing the stability of the material, corrosion resistance, etc., and is indispensable in the manufacture of high-end materials.
In the field of pesticide chemistry, 4- (trifluoromethyl) nitrobenzene is also available. It can be used as a key ingredient in the synthesis of high-efficiency pesticides, which helps to improve the efficacy of pesticides such as insecticides and weeding, and provides a strong guarantee for agricultural harvests. From this point of view, 4- (trifluoromethyl) nitrobenzene has significant value in many application fields.
Research & Development
Modern chemistry is refined, and there are many categories. Today, it is said that 4- (trifluoromethyl) nitrobenzene has been studied by many scholars for many years. At the beginning, it took a lot of trouble to get this product. The public is in the room, adjusting the agents, controlling the temperature, and observing its changes. Begin to combine various materials, or some fail to succeed, or the effect is not good. However, the public is unremitting, trying to change it again and again.
After a long time of research, the method is gradually getting better. Its yield is gradually increasing, and its quality is also more pure. And studying its properties, knowing the synthesis and decomposition of chemical chains, is of great use. In medicine, pharmaceuticals, and manufacturing materials are all important things.
Looking at it today, it was difficult to study in the past, and it is the basis for today's widespread use. We continue to work tirelessly in the research of chemistry, so that this industry can progress and create more benefits for the world.
Toxicity Research
The chemical industry is related to people's livelihood, but the study of poisons should not be careless. In today's words, the study of the toxicity of 4- (Trifluoromethyl) Nitrobenzene is particularly important.
4- (Trifluoromethyl) Nitrobenzene has a unique appearance and hidden dangers. After various experiments, it often has adverse effects on biological organisms. If you touch it carelessly, the skin may feel uncomfortable or even fester; if you inhale its qi, the lungs will be invaded and it will be difficult to breathe.
Furthermore, in the ecological environment, this thing can also cause harm. Entering the water and soil, polluting its purity, breaking the biological chain, and many living beings suffer. Therefore, it is the heavy responsibility of the chemical industry to study its toxicity and explore its harm in detail. We must be cautious, seek ways to avoid harm, ensure the safety of people's livelihood, and protect the tranquility of the ecology, so as to live up to the mission of the researcher.
Future Prospects
I have been engaged in the research of chemical products for many years, and I often think about the future of 4- (trifluoromethyl) nitrobenzene. This material is very different and can be used in all fields of chemical industry.
Looking at today's chemical industry, the demand for materials with special properties is increasing. 4- (trifluoromethyl) nitrobenzene has a unique chemical structure, and may be able to emerge in the creation of new materials. It contains trifluoromethyl, which may provide materials with excellent weather resistance and chemical resistance, and may be used in high-end coatings, special plastics and other fields in the future.
Furthermore, there are also opportunities for pharmaceutical research and development. Based on this, new compounds with unique pharmacological activities may be synthesized, providing a new way to overcome difficult diseases.
Although the road ahead is uncertain, I firmly believe that with time and unremitting research, 4- (trifluoromethyl) nitrobenzene will be able to shine in the chemical industry, medicine and other fields, and develop an infinite future vision.
Where to Buy 4-(Trifluoromethyl)Nitrobenzene in China?
As a trusted 4-(Trifluoromethyl)Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-(Trifluoromethyl)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4- (trifluoromethyl) nitrobenzene?
(Sanxiang methyl) hydroxymethyl ether, this substance is widely used in the field of medicinal chemistry.
First, in the process of drug synthesis, it is often used as a protective group. Looking at many drug molecules, among their structures, some functional groups are quite active. During the reaction, it is prone to side reactions, resulting in thorns on the road to synthesis. (Sanxiang methyl) hydroxymethyl ether can be combined with such active functional groups to protect them. After the reaction is completed, the protective group is removed by specific means, so that the functional group can regain its activity. This move is like putting armor on the delicate functional group to protect it from the battle of synthesis. For example, when synthesizing a certain type of antibiotic, the hydroxyl group has strong activity and is easy to react with other reagents by mistake. With (Sanxiang methyl) hydroxymethyl ether to protect it, the reaction goes forward and the synthesis effect is greatly increased.
Second, in the experiment of organic synthesis, (Sanxiang methyl) hydroxymethyl ether is also a good aid for constructing complex molecular structures. Due to its unique chemical properties, it can participate in specific reaction pathways and guide molecules to build in the expected direction. For example, when constructing a cyclic compound with a specific spatial configuration, the groups attached to (sanxiang methyl) hydroxymethyl ether can affect the reaction check point and reaction process through their own steric hindrance and electronic effects, helping chemists to carve out precise molecular structures, paving the way for the creation of new organic compounds.
Third, in the exploration of drug research and development, (sanxiang methyl) hydroxymethyl ether may be the key to opening the door to new drugs. Scientists modify its structure to change the physical and chemical properties of the drug molecules connected to it, such as solubility and stability. Improving drug solubility can increase its absorption and distribution in the living body; improving stability ensures that the drug is not easy to decompose and fail during storage and in vivo action. These are all key elements for the development of efficient and safe drugs, so (Sanxiang methyl) hydroxymethyl ether is of great significance in the process of drug development.
What are the physical properties of 4- (trifluoromethyl) nitrobenzene?
(Triethyl) guanidine silicon is a wonder of the creation of heaven and earth, with special physical properties. Its surface is soft in the middle, and it is as smooth as it is slippery, and it hides the power of the earth, such as the goodness of ancient times, and the exterior is soft. It can be bent and extended, and it is not easy to fold.
Its color is like a clear spring in a deep mountain. It is transparent. It refracts multicolored light under the light, like the sky and the earth, shining brightly, which makes people happy.
In addition, its performance is very good, just like the heat of summer, it can quickly measure and balance the surrounding area. This property is wonderfully useful in many situations. If it is placed in a hot place, it can make the environment drop, just like ice in the shape of ice, which is harmful to the melting of ice.
And its performance is also outstanding, such as the shield of the dharma, blocking the flow of the dharma, making it passable. In the dharma-like utensils, it can be kept safe and protected from the harm of the dharma, such as the dharma god, loyal to the dharma.
In addition, the density of (triethyl) guanidine silicon is not as heavy as the stone, nor is it like a woollen floating root. Its weight is just right, it is easy to use and carve, and it can be like the beautiful jade in the hands of the craftsman. According to the heart, it can be shaped into a dharma-like shape to meet the needs of each person.
In addition, (triethyl) guanidine silicon is a unique material, with the characteristics of softness, solidification, color, color, density, and suitability. It is a rare wonder in heaven and earth, with a wide range of uses and extraordinary value.
What are the chemical properties of 4- (trifluoromethyl) nitrobenzene?
(Triethyl) guanidinuron is a special chemical compound, and its properties are of high investigation value. This compound is white crystalline and has good quality. Under normal conditions, it is not easy to cause strong reactions in the surrounding environment, and it can maintain its own solubility.

Its solubility, (triethyl) guanidinuron can be dissolved to a certain extent in water, but the solubility is not high. Its solubility is smooth, and it is not accompanied by strong absorption or release. This solubility makes it able to disperse in an appropriate degree in aqueous solution.
Furthermore, (triethyl) guanidinuron has a certain acidity. It can produce specific chemical reactions in acid or environment, and demonstrate a certain ability. In weakly acidic or weakly acidic environments, it can maintain the chemical balance of itself and environment, avoiding large fluctuations in acidity.
Due to its chemical activity, (triethyl) guanidine urea does not affect its activity. However, under specific conditions, such as the existence of specific catalysts and appropriate conditions, it can generate a series of new compounds with different functional properties, such as substitution reactions, addition reactions, etc., and develop a series of new compounds with different functional properties.
What is the preparation method of 4- (trifluoromethyl) nitrobenzene?
The preparation method of (Sanxiang methyl) carbonyl iridium is really a delicate technique. The method is as follows:
First take an appropriate amount of pure iridium material and place it in a special crucible. The crucible needs to be cast with a material that is resistant to high temperature and chemical attack in order to withstand the harsh conditions of the subsequent reaction.
Then, slowly add a reagent containing Sanxiang methyl to the crucible. The purity and ratio of this reagent need to be precisely controlled. If there is a slight mismatch, the reaction may not meet expectations. When adding, the speed should be slow, and the materials need to be stirred continuously to mix evenly, so that the subsequent reaction can be fully carried out.
Then, place the crucible on the fire. The fire needs to be regulated according to specific laws. The initial fire should be fierce, so that the material can quickly heat up to a certain extent. When the reaction is initially initiated, it is adjusted to a mild state to maintain a stable reaction temperature. During this process, pay close attention to the signs of the reaction, such as the change of color, the escape of gas, etc., to judge the process of the reaction.
At the same time, an appropriate amount of protective gas is introduced into the reaction system. This gas can create a suitable reaction atmosphere to prevent the material from contacting with external undesirable substances, thereby ensuring the purity and stability of the reaction.
When the reaction reaches a predetermined level and exhibits specific characteristics, such as the color state and texture of the product meet expectations, the reaction needs to be stopped in time. Subsequently, the target product (Sanxiang methyl) carbonyl iridium was precisely separated from the reaction mixture by using a delicate separation and purification method, removing impurities and improving the purity of the product to obtain the refined (Sanxiang methyl) carbonyl iridium.
What are the precautions for 4- (trifluoromethyl) nitrobenzene in storage and transportation?
When storing and transporting tri (ethyl) silyl ethers, pay attention to many matters.
Choose the first environment. The storage place must be dry and cool, away from direct sunlight and heat sources. Due to sunlight and high temperature or the degradation and deterioration of compounds, their chemical properties will be damaged and their quality will be reduced. If placed near sunlight or high temperature, or cause it to decompose, the activity will be reduced, which will affect subsequent use.
The second is the choice of containers. Suitable containers should be selected, such as glass or specific plastic containers. Glass containers are chemically stable. In most cases, they do not react with tri (ethyl) silyl ethers, which can ensure their chemical structure is stable. Certain plastic materials also have good tolerance and can prevent leakage and reaction. Do not use containers made of materials that are easy to react with compounds, otherwise the chemical composition may be changed and its original properties will be lost.
When transporting, the packaging must be stable. Make sure that the packaging materials are shock-proof and collision-proof. Tri (ethyl) silyl ethers leak due to vibration, collision or damage to the container during transportation. And it is necessary to follow relevant regulations and standards to identify the name, nature and precautions of the compound, so that transporters can know the risk and take corresponding protection and emergency measures.
In addition, it is necessary to pay attention to its compatibility with surrounding substances. During storage and transportation, avoid coexistence with oxidizing, reducing or acidic and alkaline substances to prevent uncontrollable chemical reactions and cause danger. Contact with strong oxidizing agents or reducing agents, or cause violent reactions, endangering safety.