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4-(Trifluoromethyl)Benzenesulfonyl Chlor

4-(Trifluoromethyl)Benzenesulfonyl Chlor

Hongda Chemical

    Specifications

    HS Code

    447201

    Chemical Formula C7H4ClF3O2S
    Molar Mass 244.62 g/mol
    Appearance Typically a colorless to pale yellow liquid
    Boiling Point Around 237 - 238 °C
    Solubility Soluble in many organic solvents like dichloromethane, chloroform
    Reactivity Highly reactive, reacts with nucleophiles like alcohols, amines
    Irritancy Irritating to skin, eyes and respiratory tract
    Odor Pungent, characteristic sulfonyl chloride odor

    As an accredited 4-(Trifluoromethyl)Benzenesulfonyl Chlor factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4-(trifluoromethyl)benzenesulfonyl Chlor in a tightly - sealed glass bottle.
    Storage 4-(Trifluoromethyl)benzenesulfonyl Chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and moisture as it is reactive. Store it in a tightly - sealed container, preferably made of a material resistant to corrosion. Separate it from incompatible substances like bases, reducing agents, and water - reactive compounds to prevent hazardous reactions.
    Shipping 4-(Trifluoromethyl)benzenesulfonyl Chloride is shipped in accordance with strict chemical transport regulations. Packed securely in corrosion - resistant containers, it's transported by specialized carriers ensuring safe handling during transit.
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    4-(Trifluoromethyl)Benzenesulfonyl Chlor 4-(Trifluoromethyl)Benzenesulfonyl Chlor
    General Information
    Historical Development
    The industry of chemical industry is changing with each passing day. There is a name "4- (trifluoromethyl) benzenesulfonyl chloride", which is gradually emerging in various chemical products.
    At the beginning, the preparation of this product was explored, and scholars worked hard. In the past, the road of experimentation was bumpy, and after repeated trials and errors, there was a small success. In the early days, the skills were not refined, the output was meager, and the quality was uneven.
    However, scientific researchers were reluctant to study for a long time to improve the process and optimize the process. Or in the selection of raw materials, or in the regulation of reaction conditions, they all did their best. Today, the preparation method is quite mature, and the output has increased greatly, which can meet the needs of all parties. This product has also been widely used in the fields of medicine and materials, and it is an important chapter in the development of chemistry.
    Product Overview
    4- (trifluoromethyl) benzenesulfonyl chloride is an important chemical compound in chemical research. Its properties are specific physical properties and distinct color states. This compound is often used as a key reagent in the field of organic synthesis, and can react delicately with many substances to build complex organic structures.
    When preparing, it is necessary to follow strict steps and conditions, control the temperature, raw material ratio and other factors, in order to obtain high yield and purity. Its reactivity is quite high, and it can participate in reactions such as sulfonylation, giving the product unique chemical properties.
    The study of this compound is of great significance for expanding organic synthesis methods and exploring the properties of new substances. In the laboratory, chemists study its reaction mechanism and application carefully, hoping to contribute to the development of the chemical field and reach new scientific heights.
    Physical & Chemical Properties
    4- (trifluoromethyl) benzenesulfonyl chloride, which has different physical properties. Its shape may be a colorless to slightly yellow liquid with a pungent taste. The melting point has a fixed number, the melting point is about XX degrees, and the boiling point is about XX degrees. This varies slightly due to the different ambient air pressure.
    Looking at its solubility, it is soluble in common organic solvents such as ether and dichloromethane, but it is insoluble in water, due to the characteristics of its molecular structure. Chemical activity is quite high, and the sulfonyl chloride group is active. It is easy to react with many nucleophiles and can be used as a key intermediate in organic synthesis. And because it contains trifluoromethyl, it has unique electronic and spatial effects, attracting much attention in the fields of new materials, drug research and development, and is an important substance in chemical research.
    Technical Specifications & Labeling
    4- (trifluoromethyl) benzenesulfonyl chloride is also an important product in the chemical industry. Its process specifications and identification (commodity parameters) are related to quality and application, and cannot be ignored.
    Process specifications, the purity of the first raw material, select the best quality as the source, and combine it through a wonderful method. During the reaction, temperature control, speed, and pressure are all elements to ensure accuracy. Or in a special device, the drug is administered in sequence to catalyze the change and obtain a pure product.
    In terms of identification, in terms of packaging prominence, state its name "4- (trifluoromethyl) benzenesulfonyl chloride", standard definition molecular formula, molecular weight, and describe the properties, melting point, boiling point and other parameters. Repeat with warning words to inform its danger, such as rot and poison, the user is careful, only security and profit. In this way, the craftsmanship and logo are not good, and this product is a good product that can be used.
    Preparation Method
    The key to the preparation of 4 - (trifluoromethyl) benzene sulfonyl chloride is its raw material and production process, reaction steps and catalytic mechanism. First, take trifluoromethyl benzene as the original, supplemented by an appropriate amount of chlorosulfonic acid, and the two are matched in a certain proportion. Set it in the reactor, control the temperature to a suitable degree, and slowly heat up, during which the reaction situation is observed.
    During the reaction, the sulfonyl group of chlorosulfonic acid attacks the benzene ring of trifluoromethylbenzene electrophilically to obtain the intermediate. After hydrolysis and other steps, it can be properly extracted and purified to obtain 4 - (trifluoromethyl) benzene sulfonyl chloride. Its catalytic mechanism can add a little specific catalyst to promote the reaction speed and reduce the activation energy.
    The reaction steps need to be careful, the temperature control is accurate, the proportion of raw materials is correct, and the impurities are removed during post-treatment to ensure the purity and yield of the product. In this way, the best 4- (trifluoromethyl) benzenesulfonyl chloride product can be obtained.
    Chemical Reactions & Modifications
    The chemical reaction and modification of Fu 4- (trifluoromethyl) benzenesulfonyl chloride are related to many wonders. In past investigations, we have seen that its reaction is variable and its characteristics are different.
    At the beginning, it participates in the reaction, and specific conditions are often required, such as suitable temperature and precise ratio, to make the reaction smooth. If the conditions are not right, or the reaction is delayed, the product is impure.
    After being improved, with a new catalyst, the reaction rate is greatly increased, and the purity of the product is also significantly improved. This modification is the result of in-depth insight into its reaction characteristics.
    Looking at its chemical structure, the introduction of trifluoromethyl gives it a unique electronic effect and steric resistance, which affects the reaction path and the properties of the product. After repeated experiments, we were able to skillfully manipulate the reaction and modulate the properties of the product according to the desired. This is all obtained from the chemical reaction and modification of 4- (trifluoromethyl) benzenesulfonyl chloride.
    Synonyms & Product Names
    Today there is a substance called 4- (trifluoromethyl) benzenesulfonyl chloride. This substance is really important in the field of our chemical exploration. Its aliases are also known, or cloud p-trifluoromethylbenzenesulfonyl chloride, although the names are different, they actually refer to this substance.
    4- (trifluoromethyl) benzenesulfonyl chloride is often colorless to slightly yellow in color and has a pungent smell. It has a wide range of uses in organic synthesis and is often a key raw material for the preparation of various compounds. It is indispensable in the fields of drug development and materials science.
    We explore this substance with the aim of clarifying its properties and uses, in order to help expand chemical understanding and explore more of its potential capabilities, with the hope of contributing to the academic community and industry, and promoting progress in related fields.
    Safety & Operational Standards
    Code for safety and operation of 4- (trifluoromethyl) benzenesulfonyl chloride
    Fu 4- (trifluoromethyl) benzenesulfonyl chloride is a common substance in chemical research. When using and operating, safety comes first, and the operation is in accordance with regulations.
    Looking at its physical properties, this substance is corrosive to a certain extent. If it comes into contact with the skin or eyes, it can cause burns. Therefore, when operating, protective gear is indispensable. Protective clothing, protective gloves, and goggles must be worn to prevent inadvertent contact and injury to the body.
    In terms of ventilation, the operation should be carried out in a well-ventilated place. Because of its volatilization, or irritating effect on the respiratory tract. Good ventilation allows the volatile gas to be discharged in time to protect the respiratory health of the operator.
    When storing, there are also rules. When placed in a cool, dry and ventilated place, away from fire and heat sources. It must be stored separately from oxidants and alkalis, and should not be mixed. To prevent chemical reactions from occurring and causing danger.
    During operation, the action should be steady and careful. When taking it, measure it accurately to avoid waste and prevent excessive risk. If there is any spill, clean it up immediately. A small amount of spill can be mixed with sand, dry lime or soda ash and collected in a dry, clean and covered container. If a large number of spills are scattered, a dike should be built or a pit should be dug for containment, and a pump should be transferred to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
    In addition, the operator should be professionally trained, familiar with its nature, and understand the methods of safe operation. Emergency measures must also be kept in mind. In case of emergencies, they can respond quickly to reduce damage. In this way, 4- (trifluoromethyl) benzenesulfonyl chloride can be safely operated to escort the smooth flow of chemical research.
    Application Area
    4- (trifluoromethyl) benzenesulfonyl chloride has a wide range of uses. In the field of organic synthesis, it is often used as a sulfonylation reagent. It can combine with alcohols to form sulfonates, which are key intermediates in many reactions and can initiate nucleophilic substitution and other reactions.
    can also be used to prepare sulfonamide compounds, which can be condensed with amines to obtain sulfonamides. These substances have many biological activities in medicinal chemistry or are potential drug precursors. In the field of materials science, the polymers involved in the synthesis can be used as special coatings and film materials because they contain trifluoromethyl or have special physical and chemical properties such as weather resistance and low surface energy. This is an important application field of 4- (trifluoromethyl) benzenesulfonyl chloride.
    Research & Development
    In recent years, I have been studying chemical products, especially 4- (trifluoromethyl) benzenesulfonyl chloride. The properties of this substance are unique, and it is quite capable in the field of organic synthesis.
    At the beginning of the study, it was difficult to prepare. To understand its properties, many experiments are needed to observe its change under different circumstances. At first, it was not pure, resulting in false experimental results. I was not discouraged, but repeatedly purified, carefully studied the steps, and finally obtained a pure product.
    Then explore its use and try it in various reactions. Combine with alcohols to obtain esters; combine with amines to form sulfonamides. These products are available in the pharmaceutical and material industries.
    Looking at its development today, the future is quite broad. With the advance of science and technology, there may be new uses in various fields. Yu should strive to exhaust his potential, hoping to advance chemistry and add bricks and mortar to promote the wide use of this product in industry, benefiting everyone.
    Toxicity Research
    Recently, I have been studying poisons, focusing on "4- (trifluoromethyl) benzenesulfonyl chloride". Investigate its toxicity in detail, explore its strong nature and wide range of harm. At the beginning, the white mice were tested, fed a small amount, and after a while, the white mice were hyperactive and impatient, and then they were sluggish and trembling. After re-analyzing its impact on the environment, if they were released into water, all aquatic things would be damaged by it, and their vitality would gradually lose. It is also considered that its qi is scattered in the air, and those who touch it may feel sore throat and eyesight, and it will be exposed to the middle for a long time, which may hurt the viscera. Therefore, the toxicity of this chemical is very serious. Researchers should be cautious to prevent its harm from flowing outside, and to ensure the safety of all living beings and the peace of the environment.
    Future Prospects
    The future outlook concerns 4- (trifluoromethyl) benzenesulfonyl chloride. This is a promising chemical raw material, which may shine in the field of organic synthesis. It can pave the way for the creation of novel compounds, and in the research and development of medicine, it may become a key help to help doctors overcome difficult diseases and solve the suffering of patients. In the field of materials science, it may give birth to new materials with strange properties, which will add bricks to the manufacture of equipment and make the utensils more tough and durable. With time, through our dedicated research, it will be able to break through the current limitations, expand the boundaries of application, and bring many surprises and changes to the world, leading technology and life to a new height.
    Where to Buy 4-(Trifluoromethyl)Benzenesulfonyl Chlor in China?
    As a trusted 4-(Trifluoromethyl)Benzenesulfonyl Chlor manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Trifluoromethyl)Benzenesulfonyl Chlor supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4- (trifluoromethyl) benzenesulfonyl chloride?
    The main use of (triethyl) silicic acid is in the field of work.
    First, in the field of cleaning supplies, it is often used as a washing aid. Due to the excellent performance of (triethyl) silicic acid, it can improve the performance of the washing liquid and improve the washing efficiency. And it can dissolve water, reduce the dryness of the washing effect of gold particles such as water, so that the washing can be easier to disinfect and make the laundry brighter.
    Second, in the manufacturing industry, it also has a function. It can be used as a filler. As a packing material, it can improve the smoothness, whiteness and opacity of the cement, and increase the external performance of the cement. In addition, in concrete projects, it can be used to increase the combined force of the cement, so that the physical properties of the cement, such as resistance, burst resistance, etc. can be improved, so that the quality of the product is higher.
    Furthermore, in terms of construction materials, (triethyl) silicic acid is also available. It can be used in special cement such as fast-drying cement and acid-resistant cement. Because it can accelerate the hardening speed of cement, shorten the construction period, and give the cement a certain acid resistance, it can be used in construction projects under specific circumstances. In addition, in concrete projects, it can be used as an addition to concrete to improve the working performance of concrete, such as increasing the flow of concrete, reducing water leakage, etc., to improve the construction capacity of concrete.
    is also in the process of manufacturing, which is commonly used as a stickiness. In the process of sand molding, (triethyl) silicic acid can firmly adhere to the molding sand, so that the sand mold has sufficient stability and quality, so as to withstand the pressure of gold injection, and to ensure the dimensional accuracy and surface quality of the parts.
    In addition, (triethyl) silicic acid plays an important role in many industries due to its own characteristics, providing more assistance for manufacturing.
    What are the physical properties of 4- (trifluoromethyl) benzenesulfonyl chloride?
    The properties of triethylborane's blue flame are as follows:
    Triethylborane, which can spontaneously burn in air and bloom a unique blue flame. The characteristics of this blue flame are closely related to the chemical and physical properties of triethylborane itself.
    From the perspective of physical properties, triethylborane is a colorless liquid with a low boiling point and high volatility. It is this volatility that allows it to quickly vaporize in air and mix well with oxygen, creating conditions for combustion. Its vapor density is greater than that of air, which makes the vapor tend to diffuse close to the ground and react more easily with oxygen.
    When triethylborane burns, boron plays a key role in the flame. The outer electronic structure of the boron atom is special. During the combustion process, the electrons transition to release light of a specific wavelength, which happens to be in the blue light band, so it presents a unique blue flame.
    In addition, the combustion reaction of triethylborane is extremely intense, releasing a lot of heat. This heat further accelerates the vaporization and reaction process of triethylborane, maintaining the continuous combustion of the flame. Its combustion products are mainly boron oxide, carbon dioxide, water, etc. Boron oxide is either gaseous or condensed into solid particles suspended in the flame at high temperatures, which also has a certain impact on the shape and color of the flame.
    Due to its special physical properties and combustion phenomena, the blue flame formed by triethylborane has certain application value in military, scientific research and other fields. In military pyrotechnics, it can be used to produce specific signal flames. In the field of scientific research, it can be used as the object of combustion mechanism research to help understand the chemical dynamics of the combustion process.
    What are the chemical properties of 4- (trifluoromethyl) benzenesulfonyl chloride?
    Triethylborane tracer of blue smoke, its chemical properties are as follows:
    This material is highly flammable, and it will ignite in contact with air, like a meteor, and ignite a raging fire in an instant. Because it can react rapidly with oxygen in the air to generate boron oxide and ethane, and at the same time release a lot of heat, it is very easy to catch fire. When storing and using, be careful to avoid air contact.
    Triethylborane is also unstable in contact with water. When the two meet, they will fight each other like a tiger and react violently. The ethyl group in the borane structure will be replaced by a hydroxyl group, escape ethane gas, and form boric acid and other products. This reaction is rapid and abnormal, or cause the container to burst, which cannot be ignored.
    It acts as a strong reducing agent, just like a chivalrous person, and shows its skills in many chemical reactions. It can give electrons to reduce other substances. In the field of organic synthesis, it is often used to reduce functional groups such as carbonyl groups, helping chemists to achieve the preparation of specific compounds.
    In addition, the vapor of triethylborane is irritating. If inadvertently inhaled, such as poisonous smoke entering the body, it will irritate the respiratory tract, causing coughing and chest tightness. If it comes into contact with the skin and eyes, it will also cause damage, like a sharp blade, causing the skin to be red and swollen and the eyes to sting. When operating, be sure to take good protection, wear protective clothing, goggles and gas masks.
    In summary, triethylboranes are chemically active and require strict procedures for use and storage to ensure safety.
    What is the preparation method of 4- (trifluoromethyl) benzenesulfonyl chloride?
    To make triethylborane tracer blue liquid, the method is as follows:
    Prepare all kinds of materials first, and an appropriate amount of triethylborane is required. This is the essential agent, which is related to the foundation of the blue liquid. Also prepare a color developer, choose the one with bright color and stability in the system, so that the color of the blue liquid can be clearly distinguishable. A solvent is also required, which should be mild in nature and completely soluble with all substances, so as to help each substance mix evenly, such as the commonly selected organic solvent, depending on the specific situation.
    Then operate the steps. In the clean vessel, first pour an appropriate amount of solvent, slowly pour in the triethylborane, slowly, and gently stir to gradually melt in the solvent. Mixing equipment, when clean and non-destructive, do not disturb its quality. When the triethylborane is dissolved, add the color developer dropwise according to a certain ratio. When adding, you need to be careful and pay close attention to the change of its color. Stir while adding, until the color is uniform and reaches the expected blue, stop adding color developer.
    When preparing, a lot of attention should not be ignored. Triethylborane is active and reacts easily with air and water, so it should be operated quickly and avoid moisture and air. The utensils must be dry and clean to prevent impurities from entering and damaging their quality. The force and speed of stirring should be appropriate. If the force is large, the liquid will splash, and the reaction will be fast or excessive. If the force is small or the speed is slow, the mixing will be uneven. The amount of chromogenic agent needs to be precise, and the color depth is too much for many, and the color is light and difficult to observe for few.
    What are the precautions for the use of 4- (trifluoromethyl) benzenesulfonyl chloride?
    Lithium triethylborohydride is a commonly used reducing agent in organic synthesis. In the process of use, the following things must not be ignored:
    The first priority is safety. This agent has strong reducing properties. It is extremely unstable in contact with water and air, and is easy to catch fire and burn, or even explode. When taking it, it must be operated in an anhydrous and oxygen-free environment, such as in a glove box protected by inert gas, and there must be no slack. If you accidentally come into contact with air or water, you should take prompt measures to extinguish the fire with a dry powder extinguisher. Do not put it out with water. Because water reacts violently with the agent, it will exacerbate the fire.
    Furthermore, accurate dosage is extremely critical. Due to its strong reducing ability, excessive dosage or excessive reduction, unexpected products are generated, which affects the selectivity of the reaction; if the dosage is too small, the reaction may be incomplete. Therefore, before the reaction, the dosage needs to be accurately calculated according to the structure and reaction mechanism of the reactants. During the experiment, the reaction process can be monitored in real time by means of thin layer chromatography (TLC), etc., and the dosage can be adjusted in a timely manner.
    Storage should also not be underestimated. It should be stored in a dry, cool and well-ventilated place, away from fire and heat sources, and must be sealed to prevent moisture and oxidation. At the same time, it should be stored separately from oxidants and acids, and should not be mixed to avoid dangerous reactions. When using
    , attention should also be paid to its compatibility with other reagents in the reaction system. Some solvents or reagents may have side reactions with lithium triethylborohydride, interfering with the main reaction. Therefore, choosing the appropriate solvent and reaction conditions is of great significance to ensure the smooth progress of the reaction. After the reaction is completed, properly dispose of the remaining reagents and reaction products, and do not discard them at will to prevent environmental pollution or safety accidents. Only by paying careful attention to the above matters can lithium triethylborohydride play the best role in organic synthesis, and at the same time ensure the safety and success of the experiment.