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4-(Trifluoromethyl)Benzeneboronic Acid

4-(Trifluoromethyl)Benzeneboronic Acid

Hongda Chemical

    Specifications

    HS Code

    788864

    Chemical Formula C7H6BF3O2
    Molecular Weight 189.93
    Appearance White to off - white solid
    Melting Point 115 - 120 °C
    Solubility Soluble in organic solvents like dichloromethane, tetrahydrofuran
    Purity Typically high - purity, often >97%
    Stability Air - stable, but moisture - sensitive
    Boiling Point N/A (decomposes before boiling due to its solid nature and reactivity)
    Cas Number 190774 - 69 - 9

    As an accredited 4-(Trifluoromethyl)Benzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4-(trifluoromethyl)benzeneboronic Acid in a sealed, chemical - resistant bottle.
    Storage 4-(Trifluoromethyl)benzeneboronic acid should be stored in a cool, dry place, away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption, as boronic acids can react with water. Store separately from incompatible substances like strong oxidizing agents to avoid potential chemical reactions that could compromise its integrity.
    Shipping 4-(Trifluoromethyl)benzeneboronic Acid is shipped in well - sealed containers, following strict chemical transport regulations. Packaging ensures protection from moisture and damage during transit to prevent any chemical risks.
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    4-(Trifluoromethyl)Benzeneboronic Acid 4-(Trifluoromethyl)Benzeneboronic Acid
    General Information
    Historical Development
    4- (trifluoromethyl) phenylboronic acid is also an important agent in organic synthesis. Its origin was originally explored by many chemists and studied diligently in the field of organic borides. In the past, organic synthesis methods were still simple, and it was difficult to obtain such fluorophenylboronic acid compounds.
    However, the public was not discouraged, and after years of research, the synthesis method was improved. Since the beginning of the complicated and inefficient method, the process has gradually improved. In the past, the raw materials were rare, the reaction conditions were harsh, and the yield was quite low. Later, with the improvement of chemical technology, new catalysts and new reaction paths have been found, and the synthesis of 4- (trifluoromethyl) phenylboronic acid has become easier and the yield has gradually increased. From this perspective, its historical evolution is the unremitting progress of chemists, which has pioneered new paths in the field of organic synthesis and has far-reaching applications in the fields of medicine and materials.
    Product Overview
    4- (trifluoromethyl) phenylboronic acid, this compound is a key raw material for organic synthesis. Its properties are white to off-white crystalline powder with high chemical stability. In the field of organic synthesis, it is often used as an arylation reagent and plays a significant role in the construction of carbon-carbon bond reactions.
    Its preparation follows a specific chemical path, and the reaction conditions are carefully regulated to ensure the purity and yield of the product. Due to its unique physical and chemical properties, trifluoromethyl gives it a wide range of applications in pharmaceutical chemistry, materials science and other fields. In drug development, it may improve the key properties of drug molecules such as lipophilicity and metabolic stability; in the field of materials, it can optimize the electrical and optical properties of materials. It plays an indispensable role in many cutting-edge research and practical application scenarios, and is of great significance in promoting the development of related fields.
    Physical & Chemical Properties
    The physical and chemical properties of 4- (trifluoromethyl) phenylboronic acid are worth studying. Looking at its morphology, it is mostly white to white crystalline powder at room temperature. The melting point is between 134 and 138 ° C. This temperature characteristic is a key node in many reaction processes. Its solubility also has characteristics. It has a certain solubility in common organic solvents such as ethanol and ether, but it is slightly less soluble in water. From the perspective of chemical activity, this substance contains boron atoms, has a certain Lewis acidity, and can react with many nucleophiles. It is often used as an important intermediate in the field of organic synthesis, especially in the formation of carbon-carbon bonds and carbon-heteroatomic bonds. Its unique physical and chemical properties pave the way for the synthesis of a variety of organic compounds.
    Technical Specifications & Labeling
    Today there is a product named 4- (trifluoromethyl) phenylboronic acid. Its production method is related to technical specifications and identification (product parameters), which is essential.
    To make this product, you need to follow a precise method. From the selection of raw materials, there are rules. The quantity and quality of the product involved cannot be ignored. In the reaction process, temperature, duration and other variables need to be carefully controlled.
    The key to marking is to clarify its purity geometry and the condition of impurities. The appearance also needs to be described, and the color and state are the weight of the label. Its physical constants, such as melting point and boiling point, are the evidence for judging quality. In this way, we must clarify the details of the technical specifications and identification (product parameters) of this product in order to produce a good product.
    Preparation Method
    The method of making 4- (trifluoromethyl) phenylboronic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. First take the raw materials, such as benzene compounds containing trifluoromethyl, with boron sources, etc. The production process, the first reaction conditions are controlled, and the temperature, pressure and reaction time must be accurate. The reaction step is to first make the raw materials blend in a specific environment, or through substitution and addition reactions. The catalytic mechanism is also key. Choosing the right catalyst can promote the reaction rate and reduce the reaction energy consumption. For example, with a high-efficiency catalyst, the bond between the raw materials is easy to break and combine, and the reaction process is accelerated. In this way, 4 - (trifluoromethyl) phenylboronic acid can be obtained through fine operation, and its quality and yield depend on the good control of these methods.
    Chemical Reactions & Modifications
    The chemical reaction and modification of 4- (trifluoromethyl) phenylboronic acid are worth studying.

    The reaction of 4- (trifluoromethyl) phenylboronic acid is often involved in nucleophilic substitution and the like. Boron atoms have electron-deficient properties, which can attract nucleophilic reagents to them, add new groups to aromatic rings, and expand the structure of compounds. In organic synthesis, or as the basis for building complex molecules, with its reaction, specific structural goals can be achieved to meet the needs of medicine and materials.
    As for its modification, chemical modification can be used to adjust its physical and chemical properties. If different functional groups are connected, their solubility and stability can be changed. In materials, or increase its photoelectric properties to help it emerge in optoelectronic devices; in medicine, or change its biological activity and pharmacokinetics, which is beneficial to the development of new drugs. Therefore, the reaction and modification of 4- (trifluoromethyl) phenylboronic acid is essential for chemical research and also opens up many new applications.
    Synonyms & Product Names
    Today, there is a substance named 4- (trifluoromethyl) phenylboronic acid, which is quite important in chemical substances. This substance is also known as Yitong, and its synonyms are all synonymous with its original name, referring to the quality of this chemistry.
    Look at this 4- (trifluoromethyl) phenylboronic acid, which is widely used in the field of chemical industry and scientific research. It is either a reagent for reaction or a wonder for synthesis, and is commonly used in various chemical operations.
    Chemical substances, although the names are different, refer to the same. 4- (trifluoromethyl) phenylboronic acid, all synonymous names, are the convenience of recognizing and using this substance. We scientific researchers should be familiar with various names and use them without error, so that we can walk freely in the path of chemical research, in order to explore the truth, innovate and create.
    Safety & Operational Standards
    Specifications for the safety and operation of 4- (trifluoromethyl) phenylboronic acid
    Fu 4- (trifluoromethyl) phenylboronic acid is a commonly used reagent in chemical research. In order to ensure the safety of the experiment and the orderly operation, there must be strict regulations to follow.
    It may have certain chemical activity, so when storing, it should be placed in a dry, cool and well-ventilated place. Keep away from fire and heat sources to prevent them from changing due to environmental discomfort. And it must be separated from other chemicals such as oxidants and reducing agents to avoid danger caused by their interaction.
    When operating, the experimenter must wear suitable protective equipment. Wear experimental clothes to prevent it from splashing on clothes; wear protective gloves to prevent direct contact and damage to the skin; wear protective glasses to protect the eyes from accidents.
    When taking it, the action should be stable and accurate. Measure with clean and dry utensils to avoid impurities from mixing in, and to prevent material waste and latent risk from excessive use. If used in the reaction system, it is necessary to add it slowly according to the reaction procedures, pay close attention to the changes in the reaction, and observe the temperature, color, bubbles and other phenomena to prevent sudden violent reactions.
    If you accidentally come into contact with this object, rinse it with a large amount of water quickly when it touches the skin, and seek medical attention according to the situation; if it enters the eyes, you need to rinse it with flowing water immediately, and send it to medical treatment urgently. Sprinkle it on the countertop or ground, it should be cleaned up in an appropriate manner immediately. According to its chemical properties, choose an appropriate adsorbent for adsorption, collect waste, and dispose of it according to regulations. Do not discard it at will to avoid polluting the environment.
    In short, in the research operation of 4- (trifluoromethyl) phenylboronic acid, safety is the first priority, and norms are the most important, so as to ensure the smooth experiment and the safety of personnel and the environment.
    Application Area
    4- (trifluoromethyl) phenylboronic acid, which has a wide range of uses. In the field of medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of drug molecules with specific biological activities, or to develop special agents for certain diseases. In the field of materials science, it can be used to prepare organic materials with unique functions. For example, those with special photoelectric properties are expected to be applied to new display devices or sensors. In organic synthetic chemistry, it is often used as an arylation reagent to participate in many coupling reactions, build complex organic molecular structures, and provide an effective path for the synthesis of novel compounds. In fact, it has various uses and has important value and application potential in many fields.
    Research & Development
    Today, there is a product named 4- (trifluoromethyl) phenylboronic acid. In the field of chemical research, its research and development evolution is quite profound. At the beginning of my research, I explored the method of its synthesis, and through various attempts, either new agents or older methods, I hoped to achieve high efficiency. During the process, many difficulties were encountered, such as the harsh reaction conditions, and the yield was not as expected. However, I worked tirelessly to study all ends, and finally obtained a better method, so that the yield gradually increased.
    Then, the properties of this product were investigated, and its performance in different environments was observed to illustrate its chemical activity and stability. This research laid the foundation for its wider application. Today, it has been seen emerging in the pharmaceutical, materials and other industries. In the future, it is hoped that it can be expanded and used in more fields. In the process of research and development, it will be stable and far-reaching.
    Toxicity Research
    Toxicity of 4 - (trifluoromethyl) phenylboronic acid, this substance is an organoboron compound. Its synthesis often involves a variety of chemical processes. In the investigation of toxicity, it is necessary to consider multiple ends.
    Observe its structure, the introduction of trifluoromethyl or change the activity and effect of the compound. After experiments, observe its effect on biological cells. After cell line culture, it can be seen that under a certain concentration, cell growth or inhibition, metabolism is also abnormal.
    Animal experiments were also observed, and an appropriate amount was administered to the test animals to observe their physiological characteristics. Some animals are slightly uncomfortable, and organ functions may have slight changes. However, these are all preliminary results. To determine the full picture of its toxicity, it is necessary to further explore and consider the interaction of multiple factors in order to obtain a precise toxicity assessment, so as to provide a solid basis for its application and safety precautions.
    Future Prospects
    Today there is a product named 4- (trifluoromethyl) phenylboronic acid. We have been studying this product for a long time and know its properties well. Looking at the future, this product is expected to shine in the field of medicine. Due to its unique structure, it may become a key component of innovative drugs, conquer difficult diseases, and treat diseases and diseases for all living beings.
    In the field of materials, there are also endless possibilities. Its special properties may improve the properties of materials, making materials more stable and functional, and applied to high-tech products to promote scientific and technological progress.
    Our scientific researchers should make unremitting efforts to explore the potential of this product. In the coming days, 4- (trifluoromethyl) phenylboronic acid will surely be able to shine in various fields, seek well-being for future generations, and achieve a great cause, living up to the prospect of the future.
    Where to Buy 4-(Trifluoromethyl)Benzeneboronic Acid in China?
    As a trusted 4-(Trifluoromethyl)Benzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Trifluoromethyl)Benzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 4- (trifluoromethyl) phenylboronic acid
    (Triethylamino) succinic acid, this substance is useful in various fields such as medical tract, alchemy, and tool manufacturing.
    In the field of medical tract, it is crucial in the processing of pharmaceuticals. It can be used as a medicinal excipient, and by virtue of its characteristics, it can adjust the acid and base of drugs, stabilize the structure of drugs, and ensure the quality and efficacy of drugs. For example, in the preparation of some oral preparations, (triethylamino) succinic acid can help the drug components to be evenly dispersed and promote the absorption of the human body. And in the construction of drug slow and controlled release systems, it also has its function, which can precisely control the release rate and check point of drugs, make the drug effect lasting and stable, reduce the frequency of taking drugs, and increase patient compliance.
    When it comes to alchemy, alchemists regard (triethylamino) succinic acid as a wonderful thing. When alchemy, or use it to participate in the reaction, to help the transformation of alchemy sand and other golden stones. With its chemical properties, it may be able to adjust the temperature and reaction process of alchemy to make the texture, color and efficacy of the alchemy better. In the pursuit of the refining of longevity alchemy, (triethylamino) succinic acid may change the internal structure of the alchemy, making it have special medicinal power.
    In the world of tool manufacturing, in the manufacture of fine instruments, especially in the manufacture of optical and electronic devices, (triethylamino) succinic acid can be used for the synthesis of special materials. It may participate in the polymerization of polymer materials, giving the material unique physical and chemical properties, such as enhancing material flexibility, corrosion resistance, etc. When manufacturing precision optical lenses, the related materials are treated with (triethylamino) succinic acid, which may improve the optical properties of the lens, reduce light scattering and refraction losses, and make the image clearer.
    What are the synthesis methods of 4- (trifluoromethyl) phenylboronic acid?
    There are many methods for the synthesis of (triethylamino) succinic acid, each of which has its own subtlety. The details are as follows:
    First, succinic anhydride and triethylamine are used as starting materials, and the reaction is carried out under mild conditions in a suitable reaction solvent. This process is similar to the fusion of yin and yang. The active check point of succinic anhydride and the basic check point of triethylamine are attracted to each other, and the two are gradually combined. At the beginning of the reaction, the carbonyl group of succinic anhydride is attacked by the lone electron of the triethylamine nitrogen atom, like a warrior wielding a sword to hit the key point, followed by a series of electron rearrangements and chemical bonds, and finally the formation of (triethylamino) succinic acid. The raw materials of this method are common and easy to obtain, and the reaction conditions are not harsh. It is like a high-rise building on
    Second, maleic anhydride can be started, first added with triethylamine, and then through the reduction step. Just like a step-by-step strategy, maleic anhydride and triethylamine are added to build a preliminary molecular framework. This step is like drawing a blueprint to determine the approximate structure. Then the reduction step is like careful carving, converting the intermediate product into the target (triethylamino) succinic acid. Although this method has a little more steps, it can finely adjust the configuration and purity of the product, just like the craftsman carefully carving beautiful jade, and can obtain high-quality products.
    Third, it can also carry out nucleophilic substitution reaction with specific halogenated succinates and triethylamine. The halogen atom of the halogenated succinate ester is abnormally active, like an arrow waiting to be fired. The nitrogen atom of the triethylamine carries the lone pair of electrons like an arrow off the string, and quickly attacks the carbon atom connected to the halogen atom. The halogen atom leaves, forming a new carbon-nitrogen bond, and successfully builds the structure of (triethylamino) succinic acid. This method has high reaction efficiency, and can achieve the purpose of synthesis in a relatively short time, but the control of the reaction conditions needs to be accurate to avoid side reactions.
    What are the physical properties of 4- (trifluoromethyl) phenylboronic acid?
    (Triethyl) naphthalenesulfonic acid is a compound with many characteristics. Its physical properties are multi-faceted.

    Its external properties are often in the form of solid crystals. This solid or crystalline structure is exquisite, and the light is soft. If it is too small, it can be characterized by its crystal arrangement and inclusion law, just like nature's exquisite techniques.
    In terms of solubility, (triethyl) naphthalenesulfonic acid has a certain solubility in water. This property makes it easy to disperse in an aqueous environment, and water molecules interact with each other to form a homogeneous mixture. And because of its water-based nature, it can form forces such as water, which increases its dispersion in water. However, in non-soluble solvents, the solubility is limited. This is because the molecular force of non-soluble solvents is weak, so as to break the original interaction of its molecules, resulting in dissolution.
    Melting is also one of its important physical properties. Its melting is special, and a specific degree of temperature is required to make it solidify the liquid. The level of this melting is closely related to the molecular force. The higher the molecular force, the greater the energy required to break this effect, the higher the melting will be. The boiling is determined by the energy required to overcome the molecular force of the liquid. The boiling of (triethyl) naphthalenesulfonic acid is also determined by the interaction of its molecules and molecules.
    In addition, the density of (triethyl) naphthalenesulfonic acid is also fixed. Its density reflects the amount of matter contained in the molecule, and this physical quantity is related to its molecular and molecular stacking methods. Different molecular arrangements result in different molecular quantities in the molecule, resulting in a specific density value. These physical properties are of paramount importance for chemical research and multiplexing applications.
    What are the precautions for 4- (trifluoromethyl) phenylboronic acid during storage and transportation?
    When storing and transporting Sanxiang methyl taurine, many matters need to be paid attention to.
    When storing, the temperature and humidity of the environment are the first priority. This substance should be stored in a cool and dry place. If the temperature is too high, it will easily cause its properties to change. If the humidity is too high, it may also cause deliquescence and other conditions, which will damage its quality. Therefore, the warehouse needs to have precise temperature and humidity control equipment to maintain suitable conditions.
    Furthermore, light is also the key. Sanxiang methyl taurine is more sensitive to light, and long-term light exposure may cause photochemical reactions, which affects its chemical structure and properties. Therefore, it should be stored in a dark place, such as using a light-shielding container, or in a deep warehouse without direct light.
    The storage place should also be well ventilated to avoid local gas accumulation due to lack of air circulation, which will affect the stability of the material. And it should be stored separately from other chemicals to prevent mutual reaction.
    When transporting, the packaging must be strong and tight. Select suitable packaging materials to ensure that there is no leakage during transportation bumps. If a container with good sealing performance is used, the outside should be reinforced with cushioning materials.
    The condition of the transportation vehicle cannot be ignored. The vehicle needs to be clean, dry, and free of other chemical residues to avoid pollution. In summer, it is necessary to prevent high temperature and take necessary cooling measures; in winter, it is necessary to pay attention to antifreeze to ensure that the material is in a suitable temperature range.
    Transport personnel should also be familiar with the characteristics of the substance and emergency treatment methods. If there is an accident such as leakage on the way, it can be responded to quickly and properly to reduce the harm. In this way, Sanxiang methyl taurine can be properly stored and transported to ensure its quality and safety.
    What is the market price of 4- (trifluoromethyl) phenylboronic acid?
    At present, the market price of aspirin in Jiadi, Sanxiang Province is as follows.
    Between the markets, the price of aspirin often varies with quality, quantity and brand. As for ordinary products, their prices are more stable in a certain range. However, there are also some ups and downs due to changes in the situation, supply and demand.
    There are affordable aspirin, its price is suitable for the public, and it is a common choice for the common people to treat diseases. This kind of quantity is better than quantity, and it can meet the daily needs of the public. Although it is not of extremely fine quality, it can also be effective in treating ordinary diseases. The price of each dose may be between a few and more than ten texts.
    As for high-quality and well-known cards, their price is slightly higher. This kind of aspirin, with excellent selection of materials and exquisite craftsmanship, is favored by those who seek quick-acting and high-efficiency. Its price may reach dozens of words per dose, but because of its exact curative effect, there are also many people who are interested.
    There are also those who change the price due to luck. If the epidemic is rampant, and everyone is eager to seek medicine, the demand for aspirin will increase greatly, and its price may rise. On the contrary, when the epidemic ceases and supply and demand are stable, the price will also tend to slow down.
    The merchants in the city each show their ability, or they will attract customers based on the price, or they will be proud of their good quality. In the market for aspirin, although there are rules to follow, they often change according to the times. Buyers should take into account the situation and choose the appropriate one to use.