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4-(Trifluoromethyl)Benzene Sulfonyl Chloride

4-(Trifluoromethyl)Benzene Sulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    582763

    Chemical Formula C7H4ClF3O2S
    Molar Mass 244.62 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point ~245 - 247 °C
    Density ~1.58 g/cm³
    Solubility Soluble in organic solvents like dichloromethane
    Purity Typically high - purity products around 97%+
    Flash Point ~110 °C
    Hazard Class Corrosive, causes burns to skin and eyes

    As an accredited 4-(Trifluoromethyl)Benzene Sulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle of 4-(trifluoromethyl)benzene Sulfonyl Chloride, well - sealed.
    Storage 4-(Trifluoromethyl)benzene Sulfonyl Chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and moisture as it is reactive. Store in a tightly - sealed container to prevent exposure to air and humidity, which could lead to decomposition. It should be segregated from incompatible substances like bases and reducing agents.
    Shipping 4-(Trifluoromethyl)benzene Sulfonyl Chloride is shipped in well - sealed, corrosion - resistant containers. It must be transported following strict hazardous chemical regulations, ensuring proper handling to prevent leakage and exposure.
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    4-(Trifluoromethyl)Benzene Sulfonyl Chloride 4-(Trifluoromethyl)Benzene Sulfonyl Chloride
    General Information
    Historical Development
    Wenfu 4- (trifluoromethyl) benzenesulfonyl chloride originated from the progress of chemical research in the past. At the beginning, Zhu Xian worked hard in the field of organic synthesis, wanting to obtain new things to expand the boundaries of chemistry.
    At that time, the public studied the law of material reaction and explored new paths. After repeated experiments, or encountered setbacks, or achieved small success, they were all determined. Gradually, after understanding the method of synthesis, they were able to produce this 4- (trifluoromethyl) benzenesulfonyl chloride.
    Its birth was not achieved overnight, but was actually the result of day and night research and repeated experiments by advanced chemists. From the initial conception to the experimental practice, after countless hardships, this new chemical product was obtained, which was used for future chemistry, opened a new chapter, and gradually became useful in many fields such as organic synthesis and material preparation. It became an important milestone in the development of chemistry.
    Product Overview
    Today there is a product called 4- (trifluoromethyl) benzenesulfonyl chloride. This is a key reagent in organic synthesis and has a wide range of uses in many fields. Its properties are colorless to slightly yellow liquid, with a pungent odor, and easy to decompose in contact with water.
    In organic synthesis, it is often used as a sulfonylating reagent to react with alcohols, amines, etc., to generate corresponding sulfonate esters and sulfonamides. This reaction is precise and efficient, and is an important means for constructing organic molecular structures. In the field of medicine, it is used to participate in the reaction of drugs with unique biological activity and pharmacological properties. In materials science, it helps to produce polymer materials with unique functions.
    Although it is widely used, it must be used with caution. Due to its corrosive nature, contact with skin and eyes can cause serious burns. When operating, it must be carried out in a well-ventilated place according to specifications, with protective equipment to ensure safety.
    Physical & Chemical Properties
    Today there is a substance named 4- (trifluoromethyl) benzenesulfonyl chloride. Its physical and chemical properties are quite critical. Looking at its shape, it is often in a solid state, with a white or white-like color, delicate and considerable. Smell it, it has a specific smell, although not pungent, it is also clearly recognizable. Its melting point has a fixed number, about a certain range, this is the inherent nature of the substance, related to its morphological transformation.
    When it comes to chemical properties, this substance is very active. Sulfonyl chloride groups are extremely active and easily react with many reagents. When exposed to water, hydrolysis is rapid, resulting in corresponding acids and hydrogen chloride, which are its important chemical properties. It can also react with alcohols, amines and other substances to generate a variety of compounds. Because it contains trifluoromethyl, it endows the molecule with unique electronic effects and spatial effects, which affect its reactivity and product structure. All of these are important physical and chemical properties of 4- (trifluoromethyl) benzenesulfonyl chloride, and play a huge role in chemical research and application fields.
    Technical Specifications & Labeling
    There are now process specifications and identification (product parameters) for the production of 4- (trifluoromethyl) benzenesulfonyl chloride, which should be detailed. Its process specifications require the selection of fine raw materials, according to precise proportions, temperature and pressure control, and strict processes. When the material is mixed, the speed and order are heavy, so as not to make mistakes. During the reaction process, closely observe its changes, fine-tune according to the situation, and ensure a smooth reaction.
    As for the identification (product parameters), 4- (trifluoromethyl) benzenesulfonyl chloride, the appearance should be in a specific color state, the purity should reach a certain number of precision, and the impurity content should be strictly controlled at a low limit. And its physical properties, such as melting point, density, etc., are in line with the established standards, which are essential for product quality and cannot be ignored. According to this process specification and identification (product parameters), high-quality 4- (trifluoromethyl) benzenesulfonyl chloride can be obtained.
    Preparation Method
    To prepare 4 - (trifluoromethyl) benzenesulfonyl chloride, the method is as follows: Prepare raw materials, with benzene containing trifluoromethyl as the base, supplemented by sulfuryl chloride and other agents. During the reaction, the temperature is controlled appropriately, and the hydrogen on the benzene ring is replaced by sulfonyl chloride by light or initiator. The process needs to be careful, and the interference of impurities should be avoided to avoid side effects. After the reaction is completed, it is separated and purified to obtain the pure product. The method of separation, or the use of distillation and extraction, is selected according to the situation. When purifying, consider the method of crystallization and chromatography to make the product reach the standard of high purity. The preparation process, when strictly controlled conditions, ensures the stability of the reaction, so as to extract the yield and quality.
    Chemical Reactions & Modifications
    There is now a substance named 4- (trifluoromethyl) benzenesulfonyl chloride. In the field of chemistry, its reaction and modification are crucial. This compound has a unique structure. The introduction of trifluoromethyl makes the electron cloud density and chemical activity of the benzene ring change.
    In terms of its reaction, it can interact with nucleophiles, and the sulfonyl chloride group is active and prone to substitution. If it meets with alcohols, it can form a sulfonate. The control of this reaction condition is related to the purity of the product. And when it reacts with amines, it can produce sulfonamides, which is an important path for organic synthesis.
    As for modification, chemical modification can be used to adjust its chemical properties. Or introduce other groups to the benzene ring to change its solubility and stability. In this way, it can be used in various fields such as drug research and development, materials science, etc., to contribute to the advancement of chemistry and open up new frontiers.
    Synonyms & Product Names
    I have heard that there is a thing named 4 - (trifluoromethyl) benzenesulfonyl chloride. Its synonym and trade name are also researched by me. This thing is widely used in the field of chemical industry. Or used in organic synthesis, it can add help to the reaction and make various compounds.
    The synonym is due to different places and different industries, and the names are different. The trade name is related to production and sales. In order to recognize its characteristics, the merchant chooses a name that is easy to remember and shows its excellence. For our generation of chemical researchers, understanding its synonym and trade name is like holding the key to open the treasure house, which can better explore its properties and uses. Although there are various names, the essence is one, all of which are 4 - (trifluoromethyl) benzenesulfonyl chloride. Therefore, it is beneficial to study this substance in detail by studying its synonyms and trade names.
    Safety & Operational Standards
    4- (trifluoromethyl) benzenesulfonyl chloride, this substance is related to safety and operating standards, and is extremely important and should not be ignored.
    It is active, highly corrosive and irritating. When operating, be sure to follow the procedures to ensure safety. Work in a well-ventilated place, this is the first priority. Because of its volatile gas, or cause respiratory discomfort, or even injury. If inhaled, quickly move to a place with fresh air and seek medical attention if necessary.
    Furthermore, protective equipment is indispensable. Protective clothing is necessary to protect the body; protective gloves are worn to avoid touching the skin; protective goggles are worn to protect the eyes. If it accidentally touches the body, immediately rinse with plenty of water, followed by appropriate medication, and must not be slack.
    There are also rules for storage. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent accidents. And it must be stored separately from alkalis and alcohols to avoid reactions caused by their mixing.
    During operation, precisely control the amount and operate strictly. When taking it, do not spill it. If there is any spill, clean it up quickly according to the specifications. Dispose of it properly after use, and do not discard it at will to prevent pollution of the environment.
    In short, the safety and operation specifications of 4- (trifluoromethyl) benzenesulfonyl chloride are of great importance. Strict compliance with procedures and careful operation can avoid disasters, ensure safety, and promote smooth research.
    Application Area
    It is known as 4 - (trifluoromethyl) benzenesulfonyl chloride, which is used in various fields.
    In the process of medicine, this compound can be used as a key intermediate. Pharmaceutical craftsmen, based on it, through ingenious thinking, combine the active ingredients of various medicines. Its drug-helping power, treating human diseases, relieving people's suffering.
    In the field of materials, it also shows its ability. With its participation, it can make special materials with extraordinary properties, or corrosion resistance, or heat resistance, suitable for all kinds of harsh environments.
    Chemical production also relies on its work. It is an important agent for reaction, promoting chemical change, increasing the amount of products, and improving quality.
    It can be seen that this 4- (trifluoromethyl) benzenesulfonyl chloride is indispensable in the fields of medicine, materials, and chemical industry. Its power is great and far-reaching.
    Research & Development
    In recent years, Yu dedicated himself to the research of 4- (trifluoromethyl) benzenesulfonyl chloride. This compound has unique properties and wide uses, and has potential in the fields of medicine, pesticides and materials.
    At the beginning, explore its synthesis method. After various attempts, try different paths to observe the influence of reaction conditions. Temperature, proportion of reactants, and choice of catalyst are all related to yield and purity. After repeated study, a better method can be obtained to increase its yield and improve its purity.
    Then, study its properties. Measure its physical properties, such as melting point, boiling point, solubility, etc. Also observe its chemical activity and performance in various reactions. Known for its active sulfonyl chloride group, it can react with many reagents to derive a variety of compounds.
    Today, I hope to extend the research findings. Optimize the synthesis process, reduce costs and increase efficiency. Hope this achievement can promote the development of related industries, develop their strengths in practical applications, add new strength to the industry, and achieve the goal of research and development.
    Toxicity Research
    Today there is a thing called 4- (trifluoromethyl) benzenesulfonyl chloride, and we focus on poison research. The toxicity of this thing is related to all living beings and cannot be ignored.
    Looking at its chemical properties, it has a unique structure and contains trifluoromethyl and benzenesulfonyl chloride groups. It may have active chemical activity due to strong electronegativity of fluorine. After various experiments, contact with this thing may damage the skin, mucous membranes, enter the body or harm the viscera.
    Or in the field of industry, if the protection is not good, workers will touch it, and if it is light, it will be uncomfortable, and if it is serious, it will cause illness. And it is in the environment, difficult to degrade, or accumulated in water and soil, which is an ecological hazard. Therefore, studying the toxicity of this substance, formulating protective measures, reducing its harm, and ensuring the well-being of all living beings and the safety of the environment are the important responsibilities of our chemical researchers.
    Future Prospects
    Wuguanfu 4- (trifluoromethyl) benzenesulfonyl chloride is unique and has a wide range of uses. In the field of organic synthesis, it is often a key reagent, which can introduce trifluoromethyl sulfonyl into various compounds to form products with unique structures.
    Looking to the future, its development potential is extraordinary. The way of scientific research, or to explore better preparation methods, reduce costs, yield, and make it easier to obtain. In terms of application, in the creation of medicine, or due to the characteristics of trifluoromethyl, new drugs have better activity and stability, and contribute to the conquest of difficult diseases. In material science, it may be modified to produce new materials with excellent performance.
    Although the road ahead may encounter obstacles, science and technology are advancing day by day, and everyone is working together to study it, which will surely uncover more mysteries, develop its broad prospects, add luster to human well-being, and promote various fields to move forward vigorously.
    Where to Buy 4-(Trifluoromethyl)Benzene Sulfonyl Chloride in China?
    As a trusted 4-(Trifluoromethyl)Benzene Sulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Trifluoromethyl)Benzene Sulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4- (trifluoromethyl) benzenesulfonyl chloride?
    What are the main uses of (trimethylmethyl) silicic acid solution? The uses of this liquid are outlined here.
    First, it can be used for manufacturing work. In the manufacturing process, (trimethylmethyl) silicic acid solution can be used as a retention aid. It can promote the aggregation of solid particles such as rubber and fillers in the rubber, improve the retention rate, make the rubber shape better, and can speed up the water flow rate, improve the manufacturing efficiency, and improve the physical properties of the rubber, such as the viscosity.
    Second, it is also commonly used in the construction field. As the addition of building materials, (trimethylmethyl) silicic acid solution can increase the viscosity of sand, concrete, etc. It can react biochemically and generate a condensable material, improve the integrity and durability of the material, make the building more solid, and can effectively resist rain intrusion and external forces.
    Third, it plays an important role in gold anti-corrosion. The gold parts are immersed in (trimethyl) silicic acid solution, or brushed on the surface of the gold, which can form a dense protective film. This protective film can separate the bonding of metal materials such as air and water, and delay the corrosion rate of gold, improve the use of gold materials and their products, and is useful in many industries such as mechanical engineering and shipbuilding.
    Fourth, in the washing formula, (trimethyl) silicic acid solution is also an important part. It has the functions of high temperature, water melting, and dispersing dirt. It can maintain the stability of the washing liquid and increase the washing effect; it can combine with gold particles such as water, reduce the hardness of water, and prevent the formation of scale on the surface of clothes or utensils; It can disperse and float dirt particles, avoid re-sinking, and help the washing liquid to better remove dirt.
    What are the physical properties of 4- (trifluoromethyl) benzenesulfonyl chloride?
    The physical properties of triethylborane as a blue flame can be particularly investigated. When this agent burns, a blue flame appears, and its color is dull blue, which is pleasing to the eye.
    In terms of its flame temperature, although it is not as strong as a common hot topic flame, it is also quite hot, which is enough to supply energy in a specific reaction system and promote the progress of the reaction.
    Triethylborane is a highly active liquid substance under normal conditions, which is very easy to react with oxygen in the air, and then ignites into a blue flame. Its volatility is quite strong, and it quickly diffuses in the air. This property increases the area of contact with oxygen, and the combustion reaction is easy to trigger and relatively rapid.
    Furthermore, the luminosity of this blue flame is relatively soft, not bright and dazzling, but clearly discernible in the dark. And its combustion products are mostly harmless boron oxides and hydrocarbon oxidation products, which are lighter to the environment than other kinds of combustion products containing heteroelements.
    Because of its physical properties, it is often used as an initiator or fuel additive in the field of organic synthesis. With its active nature, it can trigger various reactions; with its combustion characteristics, it can optimize the combustion efficiency of fuels, improve combustion efficiency, reduce pollution and reduce emissions, and is of great value in the chemical and energy industries.
    What are the chemical properties of 4- (trifluoromethyl) benzenesulfonyl chloride?
    The chemical properties of (Sanxiang methyl) mercury chloride are as follows:
    Its color is usually white or light-colored powder or crystalline, and the outer layer is high. In terms of solubility, its solubility in water is low, and it is soluble in ordinary water-based media, but it can be partially soluble, such as ethanol, ether, etc. This property makes (Sanxiang methyl) mercury chloride have specific solubility and dispersion characteristics in the chemical reaction system.
    Due to its chemical reaction activity, its mercury molecules have certain resistance, and it is easy to generate reaction molecules or molecules. For example, it can form coordination compounds containing coordination atoms such as sulfur and nitrogen. This reaction is often used in chemical synthesis to build special molecules. In addition, (Sanxiang methyl) mercury chloride will decompose and release mercury vapor and other decomposition compounds when added or encountered with specific catalysts. Special attention should be paid to this process, because mercury vapor is toxic, and it is very harmful to environmental and human health.
    In terms of oxidative properties, the mercury element in (Sanxiang methyl) mercury chloride can be oxidized at different oxidizations. In case of oxidation, the oxidation of mercury may increase. On the contrary, in case of primary oxidation, it can be oxidized by low-grade or gold mercury. This oxidative property has important implications in some chemical analysis and environmental processes, such as in the environment, it may cause oxidative reactions to microorganisms, which may affect its existence and migration in the environment.
    What are the applications of 4- (trifluoromethyl) benzenesulfonyl chloride in synthesis?
    In the synthesis of (triethylamino) siloxy silane, it is often used in the following aspects:
    First, it can be used as a coupling agent. It can build a bridge between inorganic and organic substances, so that the two can be better combined. For example, in the preparation of composite materials, the interface affinity between inorganic and organic substances in the material is not good. After adding this substance, one end can react with the hydroxyl group on the surface of inorganic substances, and the other end can interact with organic substances, thereby enhancing the interfacial bonding force, improving the performance of composite materials, and making the material stronger and more durable.
    Second, it plays a significant role in the field of surface modification. It can change the surface properties of materials, such as some materials with poor surface hydrophilicity, which is not conducive to subsequent processing. After using this substance, the material can be given suitable hydrophilicity, or the surface roughness and chemical activity can be changed to meet different application requirements. For example, in some coating materials, surface modification can improve the adhesion and durability of the coating.
    Third, it is used to prepare organic-inorganic hybrid materials. With its special structure, the organic components and inorganic components can be cleverly combined to form hybrid materials with the advantages of both. For example, in optical materials, by combining the good processing properties of organic materials and the optical properties of inorganic materials, hybrid optical materials with excellent optical properties, good mechanical properties and easy processing can be prepared. Fourth, it is also used in catalyst support. It can modify the surface of the support, provide a suitable supporting environment for the active component, enhance the interaction between the active component and the support, improve the stability of the catalyst, optimize the activity and selectivity, and play an important role in the catalytic process of some organic synthesis reactions.
    What are the storage conditions for 4- (trifluoromethyl) benzenesulfonyl chloride?
    The storage conditions of alum sulphur in Jiadi, Sanxiang are quite exquisite. According to the ancient method, when choosing a high dry place, this is because alum sulphur is afraid of water and humidity. If it is in a humid place, it is prone to moisture change and damage its quality. Therefore, the terrain must be high and open, which can make it difficult for moisture to invade.
    And it needs to be placed in a shaded place to avoid direct exposure to the hot sun. The sulphur of alum cover stone is strong. In case of strong light and high temperature, it is afraid that its internal composition will change or cause other unexpected changes. The shaded place can keep it in a relatively constant temperature state, so that its characteristics can be maintained stable for a long time.
    Furthermore, the storage place should be well ventilated. The circulating air can disperse the turbid gas that may accumulate, and can prevent the abnormal temperature and humidity caused by air occlusion, and avoid the transformation of alum sulphur due to poor environment.
    should also be kept away from fire sources. Alum sulphur is flammable, similar to fire, and the disaster will not only destroy itself, but also cause a raging fire and endanger the surrounding area.
    To sum up, the storage of alum sulphur in Jiadi, Sanxiang Province needs to be highly dry, shaded, ventilated and away from fire sources, so that it can be properly preserved so that it does not lose its original properties and can be used in other days.