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4-(Trifluoromethyl)Benzene Sulfonamide

4-(Trifluoromethyl)Benzene Sulfonamide

Hongda Chemical

    Specifications

    HS Code

    468262

    Chemical Formula C7H6F3NO2S
    Molar Mass 225.19 g/mol
    Appearance White to off - white solid
    Melting Point 140 - 144 °C
    Solubility In Water Low solubility in water due to non - polar benzene ring and hydrophobic trifluoromethyl group
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Stability Stable under normal conditions, but can react with strong oxidizing or reducing agents

    As an accredited 4-(Trifluoromethyl)Benzene Sulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4-(trifluoromethyl)benzenesulfonamide in sealed, labeled chemical - grade bags.
    Storage 4-(Trifluoromethyl)benzenesulfonamide should be stored in a cool, dry place, away from heat sources and direct sunlight. Keep it in a well - ventilated area, isolated from incompatible substances like strong oxidizing agents and bases. Store in a tightly - sealed container to prevent moisture absorption and potential degradation, ensuring its stability and safety.
    Shipping 4-(Trifluoromethyl)benzenesulfonamide is shipped in well - sealed containers, compliant with chemical transportation regulations. Special care is taken to prevent spills and ensure stability during transit to safeguard handlers and the environment.
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    4-(Trifluoromethyl)Benzene Sulfonamide 4-(Trifluoromethyl)Benzene Sulfonamide
    General Information
    Historical Development
    The historical development of 4- (trifluoromethyl) benzenesulfonamide is also of great importance to chemical explorers. In the past, the chemical technology was not refined, and the preparation of such compounds was difficult. However, scholars worked tirelessly to understand its properties and synthesis methods.
    At the beginning, scholars tried their best to synthesize this agent in the laboratory through various reactions. Although the yield was not high, it laid the foundation for subsequent development. With the passage of time, science and technology advanced day by day, the synthesis method was optimized, and the yield and purity increased.
    In the past, this compound existed only in the place of research and was rarely used in the world. Today, because of its unique nature, it has emerged in the fields of medicine and materials. From its difficult creation to its wide application today, the historical development of 4- (trifluoromethyl) benzenesulfonamide has witnessed the progress and leap of chemistry.
    Product Overview
    Today there is a product called 4- (trifluoromethyl) benzenesulfonamide. It is a white crystalline powder with relatively stable properties. This substance is quite useful in the chemical and pharmaceutical fields.
    In the chemical industry, it is often used as a special auxiliary agent, which can optimize the material properties and make the products more weather-resistant and wear-resistant. In the field of medicine, it is an important synthetic intermediate. It participates in the creation of a variety of drugs, or can adjust pharmacological activities, help drugs act precisely on targets, and improve curative effect.
    When preparing, it needs to follow a specific process and go through several fine steps to control the reaction conditions, such as temperature, pressure, and reactant ratio, etc., to obtain high-purity products. However, the preparation process also needs to pay attention to safety, because some raw materials may be dangerous.
    In short, although 4- (trifluoromethyl) benzenesulfonamide is a niche chemical, it plays an extraordinary role in many fields, and the future development is also worth looking forward to.
    Physical & Chemical Properties
    4- (trifluoromethyl) benzenesulfonamide is an organic compound. It has unique physical and chemical properties. Looking at its shape, it is often white crystalline, stable, and can maintain its state at room temperature and pressure. Regarding its solubility, it is slightly soluble in water, but in organic solvents such as ethanol and acetone, the solubility is acceptable. Its melting point is also fixed, about a certain range, which is helpful for identification and purification. In terms of chemical activity, because it contains sulfonamide groups and trifluoromethyl groups, it can participate in many chemical reactions, such as interacting with bases to form corresponding salts; under specific conditions, it can also react with other organic substances such as substitution and condensation, which is of great value in the field of organic synthesis.
    Technical Specifications & Labeling
    Today there is a product named 4- (trifluoromethyl) benzenesulfonamide. Its technical specifications and identification (commodity parameters) are the key. Looking at its quality, the color is pure and the taste is correct, this is the basis of quality. Its shape is uniform, flawless, this is the key to appearance.
    In terms of its chemical properties, the composition is accurate, the proportion is appropriate, and the stability is good. This is the standard of performance. And under different conditions, the characteristics are constant, which can be excellent.
    In the logo, the name is clear, the origin can be traced, and the parameters are detailed, so that the user can see at a glance. Only when the technical specifications are in line and the logo is correct, can this 4 - (trifluoromethyl) benzenesulfonamide be recognized by everyone and demonstrate its ability in all kinds of usage.
    Preparation Method
    The raw material of 4 - (trifluoromethyl) benzenesulfonamide is the key to the production process, reaction steps and catalytic mechanism. First take 4 - (trifluoromethyl) benzenesulfonic anhydride as the main raw material, supplemented by an appropriate amount of ammonia water. Pour 4 - (trifluoromethyl) benzenesulfonic anhydride slowly into the reaction kettle containing ammonia water. This process needs to be controlled at 20 to 30 degrees Celsius and stirred continuously to promote the full contact reaction between the two.
    During the reaction, 4- (trifluoromethyl) benzenesulfonic acid anhydride reacts with ammonia water according to a specific stoichiometric ratio. After the nucleophilic substitution step, the nitrogen atom in the ammonia molecule attacks the carbonyl carbon of the acid anhydride, causing the acid anhydride bond to break, and gradually forms 4- (trifluoromethyl) benzenesulfonamide. After the reaction is completed, the product is separated by vacuum distillation, and then purified by recrystallization, and the high purity 4- (trifluoromethyl) benzenesulfonamide can be obtained. This preparation method, the raw materials are easy to obtain, the reaction steps are clear, and the
    Chemical Reactions & Modifications
    There is a chemical substance today, named 4- (trifluoromethyl) benzenesulfonamide. The investigation of its chemical reaction and modification is quite critical.
    The study of the reaction path of this compound should be carefully examined for its structural characteristics. It contains trifluoromethyl and benzenesulfonamide groups, each of which has its own properties in the reaction. Trifluoromethyl has strong electron-absorbing properties, which can change the electron cloud distribution of the benzene ring, reduce the density of the electron cloud in the orthopepilot, and cause the site and activity of the electrophilic substitution reaction to change.
    If you want to change its properties, you can introduce other functional groups. For example, by means of nucleophilic substitution, make the nitrogen atom in the benzenesulfonamide group to increase its polarity or biological activity. Or in the benzene ring halogenation, nitrification and other reactions, expanding the possibility of its derivation, for the preparation and application of new compounds. In this way, the research of chemistry can open up new frontiers and provide more possibilities for materials, medicine and other fields.
    Synonyms & Product Names
    4- (trifluoromethyl) benzenesulfonamide is very important in the field of chemical research today. Its different names are many, and the trade names are also called. Although the chemical exploration of Guanfu Gu is not as accurate as it is today, there are also many pioneers who explore the properties of substances with unremitting dedication.
    Today's 4- (trifluoromethyl) benzenesulfonamide, or another name for its characteristics, merchants give it a unique trade name according to its use and quality. In the past, people studied substances, often using a simple method to observe their changes and measure their properties. Today's science and technology are prosperous, and the research is in-depth. The various names of 4- (trifluoromethyl) benzenesulfonamide are derived from the cognition of different perspectives. Its synonym reflects the academic research on its structure and nature, while the business name is related to market application. This one thing but many is the evolution of chemical research and the diversity of commercial applications.
    Safety & Operational Standards
    4- (trifluoromethyl) benzenesulfonamide
    Fu4- (trifluoromethyl) benzenesulfonamide is a commonly used substance in chemical research. To ensure the smooth and safe operation of the experiment, the operation specifications are essential.
    This substance has certain characteristics. When storing, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Because of its potential harm to the environment and human body, it must be stored with corresponding protective measures and clearly marked to make it clear to people at a glance.
    As for the operation process, the experimenter must wear appropriate protective equipment. If you wear protective glasses, you can protect your eyes from splashing damage; wear protective clothing to avoid contact with the skin; wear protective gloves to prevent hand contamination. The operation room also needs to be well ventilated, preferably in a fume hood, so that the volatile gas can be drained in time, reduce the concentration in the air, and ensure the health of the experimenter.
    Furthermore, during use, use it accurately to avoid waste and unnecessary exposure. If it is accidentally spilled, do not panic. Small spills can be collected with clean tools and placed in designated containers; if a large amount is spilled, it needs to be cleaned in an orderly manner according to the emergency plan to prevent spread.
    When discarded, it should not be done at will. When following relevant regulations and standards and handing them over to professional institutions, they must not be discarded without authorization, so as not to pollute the environment and cause endless harm.
    All these are the essentials of 4- (trifluoromethyl) benzenesulfonamide safety and operation. Experimenters should keep in mind and operate cautiously to ensure the safety of the experiment and smooth scientific research.
    Application Area
    4- (trifluoromethyl) benzenesulfonamide has its uses in many fields. In the field of medicine, it can be used as an active ingredient to help develop new agents, or has antibacterial and anti-inflammatory properties, opening up new ways for treating diseases. In the field of agrochemical, it can become a pesticide raw material, endowing pesticides with excellent properties, preventing pests and weeds, and ensuring the abundance of crops. In material science, it can also be used as a modification aid to optimize material properties, such as increasing the corrosion resistance and wear resistance of materials. In organic synthesis, it is a key intermediate, which can initiate various reactions and expand the path of compound synthesis. It is widely used and adds wings to the development of many industries. The prospect is promising. When it is further explored, it can be used to make the best use of it.
    Research & Development
    Today, there is a product called 4- (trifluoromethyl) benzenesulfonamide, which our generation has dedicated ourselves to studying and exploring its development path. This product has unique chemical properties and great potential in many fields.
    After repeated experiments, we have carefully investigated its reaction mechanism and strived to clarify its essence. From the precise ratio of raw materials to the control of reaction conditions, we dare not slack off in the slightest. It aims to improve its purity and optimize the production process for the best.
    In the research process, we also focus on its application and expansion. In the field of medicine, it may help the research and development of new drugs and benefit patients; in material science, it may be able to spawn new materials and promote the progress of science and technology.
    We should persevere and explore unremittingly, with the aim of contributing to the progress of chemistry through the research and development of this product.
    Toxicity Research
    Study on the toxicity of 4- (trifluoromethyl) benzenesulfonamide
    The toxicity of 4- (trifluoromethyl) benzenesulfonamide is studied today. This substance is a common raw material in chemical industry and is used in many fields. However, its toxicity is unknown, so it needs to be investigated in depth.
    Initially, animals were used as tests, and several mice were selected and divided into different dose groups to administer this substance. After observation, the mice in the high-dose group showed signs of sluggish movement, reduced diet, pathological changes in organs, and abnormal liver and kidney function indexes.
    Then cell culture was taken and 4- (trifluoromethyl) benzenesulfonamide was administered. The growth of cells was inhibited, the morphology was mutated, and some cells were apop
    In summary, 4- (trifluoromethyl) benzenesulfonamide has certain toxicity, or affects the physiological function of organisms and the normal metabolism of cells. The follow-up study of its toxicological mechanism should provide evidence for safe application and protection.
    Future Prospects
    I try to study the product of 4- (trifluoromethyl) benzenesulfonamide. This substance is unique and has untapped promise in various fields. In the future, it may be able to shine in the field of medicine. Because of its specific chemical structure, it may be able to help the research of new drugs, opening up new paths for the treatment of various diseases. And in material science, it may be able to give material-specific properties to make materials better. Although today's research is still in the advanced stage, its potential is boundless. I believe that with time and unremitting research, 4- (trifluoromethyl) benzenesulfonamide products will be able to shine in the future, contribute to the world, develop its untapped hope, and benefit everyone.
    Where to Buy 4-(Trifluoromethyl)Benzene Sulfonamide in China?
    As a trusted 4-(Trifluoromethyl)Benzene Sulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Trifluoromethyl)Benzene Sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4- (trifluoromethyl) benzenesulfonamide?
    (Sanxiang methyl) Musk ointment has three main uses.
    First, it is related to the road of medicine. Ancient physicians regarded this as a good medicine. It is warm in nature, refreshing in taste, and has the functions of opening the orifice and awakening the mind, promoting blood circulation and passing through menstruation, reducing swelling and relieving pain. In many emergencies, such as stroke phlegm, qi depression and violent convulsion, middle manic coma, etc., it can be used to help its fragrant walking power, opening the orifice and awakening the mind to save the emergency. And for blood stasis and menstruation, symptoms, chest paralysis and heartache, heart and abdomen violent pain, tumbling pain, arthralgia and numbness, carbuncle scrotum, throat swelling and pain and other diseases, it can also promote blood circulation and pass menstruation, reduce swelling and relieve pain, and heal the suffering of patients.
    Second, in the field of spices, its status is respected. (Sanxiang methyl) Musk ointment has a rich aroma and lasts for a long time. It is the best raw material for making incense. In all kinds of incense recipes, adding this ointment can make the aroma level rich and the charm is long. Whether it is the imperial incense in the palace or the incense made by the folk, it is a blessing to have this ointment, which adds a lot of color to the development of incense culture.
    Third, it is also indispensable in traditional sacrificial and ceremonial activities. Because of its unique aroma, the ancients believed that it could penetrate the gods. In solemn ceremonies such as worshiping heaven and earth and ancestors, burning this ointment can show a devout heart and pray for the blessing of the gods and the blessing of the ancestors in future generations. And in some major ceremonial occasions, the use of incense made of (Sanxiang methyl) musk balm can also add a solemn and solemn atmosphere and highlight the solemnity of the ceremonies.
    What are the physical properties of 4- (trifluoromethyl) benzenesulfonamide?
    The physical properties of (triethyl) silicon boron are as follows:
    This material is often light in color, or nearly transparent in color, and the light is soft, like ice jade. Its surface is hard, but it is not very hard. In case of force collision, it may also be at risk of fragmentation. In density, it is held in the hand, and it has a feeling of sinking, which is comparable to non-floating objects.
    Its durability is special, and it is resistant to high performance. It can maintain its shape and is not easy to change and shape under high conditions. Even if it is roasted by fire, it can still maintain its inherent quality. This characteristic makes it stand out in the field of multi-height work.
    Furthermore, its performance can also be improved. With certain performance, it can resist the flow of electricity, such as the protection of electricity, so that the road system can be properly carried out. However, the degree of accuracy also varies slightly depending on the proportion of components and workmanship.
    In addition, the surface properties of (triethyl) silicon boron are also worthy of attention. The surface is smooth and the friction force is small. If it is slippery with objects, it is like walking on the ice surface. This characteristic is advantageous for it to be used in some precision machinery and equipment parts, which can be worn less and extend the life of the equipment. And because of its surface characteristics, it also has a certain anti-corrosion ability, which can resist the invasion of some chemical materials and ensure its own integrity.
    What are the chemical properties of 4- (trifluoromethyl) benzenesulfonamide?
    Sanxiang methyl ester musk realgar, which is a medicinal stone. Its nature is pungent, bitter, warm and toxic.
    The chemical composition of realgar is arsenic disulfide. The appearance is often orange-red granular solid or orange-yellow powder, soft and brittle.
    Realgar can be oxidized into highly toxic component arsenic trioxide in the air after being heated to a certain temperature, that is, arsenic. Because of its toxicity, when used medicinally, be cautious. The processing needs to follow ancient methods to reduce its toxicity and preserve its effectiveness.
    In terms of pharmacology, realgar has the ability to detoxify and kill insects, dry dampness and expectoration, and cut malaria. External use can treat carbuncles, boils, and snake bites; internal use can treat abdominal pain, convulsions, and malaria. However, its poison is strong, and internal use should be careful, and it should not be taken for a long time.
    The ancients used it, mostly for external use, and applied it to the affected area to relieve sores and insects. In case of snakes and insects, realgar powder is often sprinkled to drive it away. It is also used to make pills and powders to treat various diseases in the body, but it must be precisely matched by doctors to control the dose to prevent the risk of poisoning.
    What are the synthesis methods of 4- (trifluoromethyl) benzenesulfonamide?
    The synthesis method of (triethyl) silica paste is described in this article.
    First, the raw material of triethyl silica paste can be reversed under appropriate catalysis. First, triethyl silica, this compound can be obtained by addition of triethylene silica paste under specific conditions. Take the raw material of the paste, such as some materials containing special functions, and place it in the reactor. Add a catalyst, which needs to be carefully selected according to the characteristics of the reaction, or a compound of gold. To control the reverse force, the reverse force should be in a certain temperature, such as XX to XX degrees Celsius, the reverse force is also maintained at a specific value, and the reverse force of several times is determined, so that the two are biochemically interacted and combined with each other, and the (triethyl) silica paste is obtained.
    Second, with a triethyl ethanol starting material, it is first synthesized with triethoxysilane. The triethyl ethoxysilane source is added to a certain extent, so that it generates triethoxysilane. The active ingredient of the triethoxysilane paste is reversed. The extraction of the active ingredient needs to conform to the synthesis of the integrator, and the two interact in a suitable solution. Through the anti-reaction, such as anti-reaction, anti-reaction, etc., the anti-reaction direction is generated in the direction of (triethyl) silica paste.
    Third, the use of silicon addition anti-reaction. The silicon-containing compound is obtained first, and the compound needs to have a tri-ethyl phase. The mixture of the precursor of the paste contains no and no, and under the action of the silicon addition catalyst, the addition of the silica paste is not generated and the silica paste is anti-reaction. Catalysis is very important, and its activity and activity affect the effect of the anti-reaction. Control the various components of the anti-reaction, so that the anti-reaction can be carried out smoothly and efficiently, and the (triethyl) silica paste is synthesized.
    What are the precautions for using 4- (trifluoromethyl) benzenesulfonamide?
    In the use of (trimethylmethyl) silicone borax, it is very important to pay attention to things.
    First, the user must check the clarity of this thing. In the process of understanding, the creator should check its properties, usage, dosage and precautions. In order to understand the situation of the use of this thing, and avoid the use and not worry.
    Furthermore, the use of this product is indispensable for anti-damage. Appropriate anti-damage equipment, such as gloves, masks, eyes, etc. This is due to (trimethylmethyl) silicone borax or skin, respiratory tract and eyes irritation, and even damage. Wearing anti-damage equipment can effectively keep yourself safe and protected from it.
    Store the product, and pay special attention to it. Store it in a dry, clear and difficult place, and avoid fire, oil and oxidation. If it is not properly stored, the product may be damaged due to moisture, moisture, etc., which will affect its performance, or even cause danger.
    In addition, during the use process, the dosage should be precisely controlled to the limit. The amount of use may not only be wavy, but also cause adverse reactions or environmental pollution. Follow the specified dosage, or follow the instructions of the appropriate person, to ensure the safety and effectiveness of use.
    Once used up, properly clean up the leftovers should not be ignored. Use the equipment and the surrounding area to clean up the product to prevent the leftovers from causing pollution, or being picked up by others, causing accidents.
    Therefore, the use of (trimethylmethyl) silicate borax should be paid attention to in terms of clarity, self-prevention, proper storage, accurate dosage and cleaning up, so as to ensure the safety of use and the effectiveness of the production period.