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4-Trifluoromethyl Benzene Methanol

4-Trifluoromethyl Benzene Methanol

Hongda Chemical

Specifications

HS Code

621684

Chemical Formula C8H7F3O
Molar Mass 176.14 g/mol
Appearance Colorless liquid
Boiling Point 190 - 192 °C
Melting Point N/A
Density 1.24 g/cm³
Flash Point 75 °C
Solubility In Water Insoluble
Vapor Pressure Low
Refractive Index 1.453 - 1.455

As an accredited 4-Trifluoromethyl Benzene Methanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 kg of 4 - trifluoromethyl Benzene Methanol in sealed, corrosion - resistant chemical - grade packaging.
Storage 4 - Trifluoromethyl Benzene Methanol should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent vapor leakage. Due to its potential reactivity, it should be separated from incompatible substances. Use appropriate storage cabinets or areas compliant with safety regulations to ensure stability and safety.
Shipping 4 - trifluoromethyl Benzene Methanol is shipped in well - sealed, corrosion - resistant containers. Special care is taken to ensure compliance with chemical transportation regulations, with proper labeling indicating its nature and handling precautions.
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4-Trifluoromethyl Benzene Methanol 4-Trifluoromethyl Benzene Methanol
General Information
Historical Development
4-Trifluoromethylbenzyl alcohol is an important agent in organic synthesis. Although its origin cannot be traced back to ancient times, it has gradually developed since chemical technology, and the research and application of this substance have become more and more complicated.
At the beginning, chemists only knew its basic properties, and the synthesis method was also very crude, the obtained product was impure, and the yield was meager. And the evolution of science, all kinds of new technologies and new methods have emerged. The improvement of catalysts and the precise regulation of reaction conditions have gradually improved the synthesis of 4-trifluoromethylbenzyl alcohol.
In the past, synthesis often required multiple steps, which took a long time and cost. Nowadays, with the help of an efficient catalytic system, high-purity products can be obtained in one step or a few steps, which can be used in various fields such as medicine and pesticides to help the development of the industry. Its historical evolution is a testament to the progress of chemistry.
Product Overview
4-Trifluoromethylbenzyl alcohol is an organic compound. It may be a colorless liquid with a special odor. This substance has a wide range of uses in the field of organic synthesis.
The preparation method often uses benzene containing trifluoromethyl as the starting material, and the product is obtained through several steps of reaction. During the reaction, it is necessary to select suitable reagents and control precise conditions to obtain satisfactory yields.
4-trifluoromethylbenzyl alcohol is important in pharmaceutical chemistry, materials science, etc. In pharmaceutical research and development, it can be used as a key intermediate to help form molecules with special pharmacological activities; in the field of materials, it can improve the characteristics of materials, such as enhancing their stability and weather resistance. Its unique structure, containing trifluoromethyl and hydroxymethyl, gives it different physical and chemical properties, which is also the basis for its wide application.
Physical & Chemical Properties
4-Trifluoromethylbenzyl alcohol is also an organic compound. Its physical and chemical properties are related to many studies. This substance may be in a liquid state at room temperature and has a specific color and odor. Its boiling point and melting point are also one of its characteristics. The boiling point is related to the temperature of gasification, and the melting point is related to the transition between solid and liquid states.
Solubility is also key, and the degree of solubility varies in different solvents. In water, it may be insoluble, while in some organic solvents, it may be soluble. Chemically, it can participate in a variety of reactions because it contains specific functional groups. Hydroxyl groups can cause nucleophilic substitution, while trifluoromethyl affects the distribution of electron clouds, making the reaction activity unique. These properties are of great significance in the fields of organic synthesis and drug development, and are the key to chemical research.
Technical Specifications & Labeling
Technical Specifications and Labeling of 4-Trifluoromethylbenzyl Alcohol (Product Parameters)
There is 4-trifluoromethylbenzyl alcohol today, and its technical specifications are the key. To observe its synthesis method, it is necessary to follow precise steps. The amount of raw materials, reaction temperature and time length are all fixed. The raw materials are selected with high purity to make the reaction smooth and the product pure.
The reaction temperature should be controlled within a certain range. If it is too high, the side reactions will be raw, and if it is too low, the reaction will be slow. The duration must also be appropriate to achieve the best degree of reaction.
As for the label (product parameters), its appearance, purity, impurity content, etc. should be clear. Appearance or a specific color, shape, purity must reach a certain standard, impurity content must be extremely low. In this way, this product can be used in various application scenarios to show its effectiveness and meet everyone's expectations.
Preparation Method
The preparation method of 4-trifluoromethylbenzyl alcohol is related to the raw materials and production process, reaction steps and catalytic mechanism, which is the key to chemical research. The selection of raw materials should be a compound with trifluoromethyl and groups that can be converted into hydroxyl groups, such as trifluoromethylbenzaldehyde. This aldehyde can be reduced to obtain the target product.
In the production process, the catalytic hydrogenation method is often used. In a suitable reaction vessel, put trifluoromethylbenzaldehyde, select a catalyst with high activity and good selectivity, such as platinum, palladium and other precious metal catalysts, use alcohol as the solvent, and introduce hydrogen at a certain temperature and pressure. The reaction step is to mix the raw material and the catalyst thoroughly, and then slowly raise the temperature to a specific reaction temperature, usually in the tens of degrees Celsius, while adjusting the pressure in the range of several megapascals. The hydrogen is activated by the catalyst, attacking the aldehyde group and reducing it to a hydroxyl group.
The catalytic mechanism is that the active check point on the surface of the catalyst adsorbs hydrogen molecules and dissociates them into hydrogen atoms. At the same time, the aldehyde group is also adsorbed on the surface of the catalyst. The hydrogen atom is combined with the carbon atom of the carbonyl group in the aldehyde group, and then the oxygen atom is combined with the proton in the solvent to finally produce 4-trifluoromethylbenzyl alcohol. This preparation method is finely regulated to obtain high-purity products to meet the needs of different fields
Chemical Reactions & Modifications
Chemists often study the changes of substances in order to understand their reasons and seek new methods. In this sentence, the chemical reaction and modification of 4-Trifluoromethyl Benzene Methanol are quite important.
To obtain this substance, the method of common reactions may be converted by a certain precursor in several steps. However, the traditional method may be cumbersome and inefficient. Therefore, scholars think about changes and want to improve it.
In the way of modification, special agents can be added, or the temperature and pressure of the reaction can be changed to make the product better. In this way, not only can the purity of the product be increased, but also its yield can be improved.
Scholars have always been committed to innovation, exploring the secrets of chemical reactions and seeking the best methods for modification, hoping to use this material as a basis to open up a new path for chemical research and benefit the world.
Synonyms & Product Names
4-Trifluoromethylbenzyl alcohol is now known by its synonymous name and the name of the commodity. This substance, or "trifluoromethylbenzyl alcohol" is called, all refer to this substance. In the field of chemical industry, there are many people with different names but the same. This is also an example. Although its name is unique, its physical properties are the same. Looking at the ancient books, although the chemical industry is not as prosperous as it is today, the distinction between the name and the truth is also the gist. Today's 4-trifluoromethylbenzyl alcohol, for the industry, is known by its synonymous name and the name of the commodity, so that it can be used and its way can be clarified. Do not misjudge the fact by different names, but examine its nature in detail and study its quality, which is the way to study chemical industry. In this way, the knowledge of 4-trifluoromethylbenzyl alcohol can be deepened.
Safety & Operational Standards
Specifications for the safety and operation of 4-trifluoromethylbenzyl alcohol
F 4-trifluoromethylbenzyl alcohol is also a chemical research material. Its nature is special, and it is related to safety and operation regulations, which cannot be ignored.
At the safe end, the first protection. This substance has a certain degree of irritation, touching the skin, or causing discomfort, or even injury. Therefore, when handling, it is necessary to wear protective equipment, such as gloves, goggles, etc., to avoid damage to the skin, eyes and eyes. And its gas or odor, and or a certain degree of toxicity, in the place of operation, should be well ventilated, so that the turbid gas can quickly disperse, so as not to cause illness by inhalation.
As for the operating specifications, when weighing, use a precise device to ensure the accuracy of the quantity. When dissolving or reacting, control the temperature and speed according to its nature. It may have the ability to corrode certain materials, so the device used must be carefully selected to prevent it from being damaged and leaking. The environment where the reaction occurs, or inert gas protection is required, should be followed to avoid accidents.
The method of storage should not be ignored. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Store separately with other things to avoid reactions caused by mixing with them.
In short, handling 4-trifluoromethylbenzyl alcohol requires safety and follows the rules of operation to ensure smooth chemical research and avoid accidents.
Application Area
4-Trifluoromethylbenzyl alcohol is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of specific drugs. Taking a new antimalarial drug as an example, 4-trifluoromethylbenzyl alcohol can introduce key structural fragments through several delicate reactions, which greatly increases the inhibitory effect of the drug on malaria parasites.
In the field of materials science, it also has its uses. Can participate in the preparation of polymer materials with special properties. If polymerized with specific monomers, the resulting polymer has excellent weather resistance and chemical stability, and is very popular in the manufacture of outdoor facilities and chemical container materials.
Furthermore, in the field of fine chemicals, 4-trifluoromethylbenzyl alcohol can be used as a raw material for fragrance synthesis. After clever blending and reaction, it can generate a fragrance with a unique aroma, which is used in the manufacture of high-end perfumes and cosmetics to increase its unique flavor and quality. From this point of view, 4-trifluoromethylbenzyl alcohol has important value in various application fields.
Research & Development
Yu Taste is dedicated to the research of chemical products, and recently focused on the product 4 - Trifluoromethyl Benzene Methanol. Its characteristics are unique and have potential applications in various fields.
When researching, study its synthesis method in detail. At first, the conventional technique was ineffective and the yield was quite low. After repeated research, try to use new agents and change its process, and gradually get the best method, and the yield increased.
And study its properties, test its structure and identify its characteristics with advanced equipment. Know that under specific conditions, it can react with various substances to form novel compounds, and pave stones for expanding its use.
As for development, this product is expected to become a key agent in the field of medicine and materials. With time, we can study its properties and make good use of its capabilities, or we can start a new chapter in chemical applications, adding brilliance to the industry.
Toxicity Research
The toxicity of 4-trifluoromethylbenzyl alcohol has been studied in this study. The use of this substance is becoming more and more widespread, but its toxicity is still unknown to us. I use ancient methods to observe its impact on various things. Take a few species of insects and ants, put them in the environment containing this substance, and observe their behavior and survival. And grass and wood are planted in the place where this substance is applied to observe its growth, prosperity and withering changes.
Over time, I see that insects and ants are uncomfortable, slow to move, and even die. The grass and trees are also abnormal, and the leaf color is yellow, and the growth is blocked. From this perspective, 4-trifluoromethylbenzyl alcohol is toxic. Although it is not fully understood, its harm has been seen. The follow-up should be further investigated to clarify its toxic mechanism in order to avoid its harm and make good use of this substance.
Future Prospects
In the future, I look forward to 4-Trifluoromethyl Benzene Methanol. It is unique in nature and has a wide range of uses, and has potential in various fields. In the field of chemical industry, it can be used as a raw material to generate novel products; in the field of medicine, it can become a wonderful medicine to heal diseases. Although what we know is still limited, I firmly believe that with time, we will be able to dig deeper into its capabilities. The road of scientific research is explored step by step, the technology is new, and its application may be as bright as stars. In the future, it may emerge in the field of environmental protection, helping mountains and rivers to clear the sky; or it may make achievements in high-tech and promote the times to move forward. We should study diligently, hoping that this product will shine in the future and add brilliance to the world.
Where to Buy 4-Trifluoromethyl Benzene Methanol in China?
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Frequently Asked Questions

As a leading 4-Trifluoromethyl Benzene Methanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-trifluoromethylbenzyl alcohol?
Triethylaminoformyl chloride is a crucial reagent in organic synthesis. Its main uses probably have the following ends.
First, in the field of drug synthesis, its role is quite critical. It can be used as a key intermediate to prepare many biologically active drugs. For example, in the synthesis path of some anti-cancer drugs, triethylaminoformyl chloride participates in specific reaction steps. By condensing with other compounds, it builds the specific structure of drug molecules, endows drugs with corresponding pharmacological activities, and provides a strong material basis for combating diseases such as cancer.
Second, it also plays an important role in pesticide synthesis. With its help, it can synthesize a variety of high-efficiency pesticides, like some new insecticides. Triethylaminoformyl chloride reacts with compounds containing specific functional groups to generate pesticides with unique insecticidal mechanisms, which can effectively control various crop pests and ensure the yield and quality of crops. It is of great significance to the stability and development of agricultural production.
Third, in the field of materials science, it also has its place. In the preparation of some polymer materials with special properties, triethylaminoformyl chloride can be used as a modifier to participate in the reaction. By reacting with the chain segment of the polymer, the surface properties and solubility of the material can be changed, so that the material can meet the special needs of different fields such as coatings and adhesives, and expand the application range of materials.
Fourth, in the basic research of organic chemistry, triethylaminoformyl chloride is a very commonly used reagent. Scientists use it to explore new organic reaction pathways and mechanisms, and to enrich the theoretical system of organic chemistry by studying its reaction characteristics with compounds of different structures, providing theoretical basis and practical experience for the development of organic synthesis methodologies, and promoting the continuous development of organic chemistry.
What are the physical properties of 4-trifluoromethylbenzyl alcohol?
Triethylmethylbenzyl ammonium chloride is a common organic compound. Its physical properties are worth attention.
Looking at its appearance, under normal circumstances, it is mostly white crystalline powder, with fine texture, smooth touch, and good fluidity. It is easy to handle in many operations.
When it comes to solubility, this compound has good solubility in water and can be quickly dispersed to form a uniform solution. And it also has good solubility in common polar organic solvents such as ethanol and acetone. This property makes it convenient to participate in the reaction in many chemical reactions and industrial applications, or as an auxiliary agent evenly dispersed in the system.
Its melting point is also an important physical property. It has been determined that the melting point of triethylmethyl benzyl ammonium chloride is within a specific range. This melting point value enables it to realize the transformation of solid and liquid states under specific temperature conditions, providing a basis for the control of related processes. And because of its melting point characteristics, during storage and transportation, it is necessary to pay attention to the influence of temperature to prevent its morphology from changing due to improper temperature.
Furthermore, the density of this compound also has its own characteristics. Its density gives it a specific distribution state in the mixed system, which affects the delamination and mixing effect of the substance during liquid-liquid reaction or separation.
In addition, triethylmethyl benzyl ammonium chloride has certain hygroscopicity. In a high humidity environment, it is easy to absorb moisture in the air, causing its own state to change. Therefore, during storage, it is necessary to pay attention to moisture resistance to ensure its stable quality.
What are the chemical properties of 4-trifluoromethylbenzyl alcohol?
Triethylbenzyl ammonium chloride is a common quaternary ammonium salt compound. It has several characteristics and has a wide range of uses.
Looking at its physical properties, this compound is mostly white crystal or powder at room temperature. It is easily soluble in water and can be well dissolved in polar organic solvents, such as alcohols and acetone, but its solubility in non-polar organic solvents is not good. Its melting point is about 119-123 ° C, which can be used in specific separation and purification processes.
When it comes to chemical properties, the quaternary ammonium cation in triethylbenzyl ammonium chloride has a certain degree of positive electricity, which makes it show the commonality of salts. Its chloride ions can undergo substitution reactions under appropriate conditions. For example, when meeting a nucleophilic reagent, chloride ions can be replaced by nucleophilic groups, which is often used in organic synthesis. When used as a phase transfer catalyst, it can effectively promote the progress of two-phase reactions. Because it can transfer nucleophilic reagents in the aqueous phase to the organic phase, accelerate the reaction rate and improve the reaction efficiency, it is widely used in many reactions such as nucleophilic substitution of halogenated hydrocarbons and cyanidation reactions.
In addition, triethylbenzyl ammonium chloride has high stability and is not easy to decompose under normal conditions. When encountering strong oxidizing agents, an oxidation reaction may occur, resulting in structural changes. Because it belongs to quaternary ammonium salts, although it is relatively stable in an alkaline environment, under the action of strong bases for a long time, the structure of quaternary ammonium cations may change and reactions such as Hoffman elimination occur. This compound plays an important role in the field of organic synthesis. With its unique chemical properties, it helps to prepare many complex organic compounds and contributes greatly to the development of organic chemistry.
What are the preparation methods of 4-trifluoromethylbenzyl alcohol?
There are several ways to make triethylbenzyl ammonium chloride.
First, benzyl chloride and triethylamine are used as raw materials. The two are combined and the reaction is quite direct. Take an appropriate amount of benzyl chloride and place it in a clean reactor. The kettle needs to be dry and well sealed to prevent impurities from mixing. Then, slowly add triethylamine, and pay close attention to the reaction temperature. Because the reaction may exothermic, it is necessary to control the temperature. A cold water bath or other cooling device can be used to maintain the temperature within an appropriate range to prevent the reaction from being too violent. During this process, the chlorine atom of benzyl chloride is combined with the nitrogen atom of triethylamine to gradually generate triethylbenzyl ammonium chloride. After the reaction is completed, the product can be purified by recrystallization with suitable solvents such as ethanol and acetone, and the unreacted raw materials and impurities can be removed to obtain pure triethylbenzyl ammonium chloride.
Second, the hydrochloride of benzyl chloride and triethylamine is used as the starting material. First prepare the hydrochloride of triethylamine, take an appropriate amount of triethylamine, slowly add hydrochloric acid, pay attention to control the reaction rate and temperature, so that the two fully react to form triethylamine hydrochloride. After that, the hydrochloride and benzyl chloride are co-placed in the reaction system, and an appropriate amount of catalyst, such as some quaternary ammonium salt catalysts, is added to promote the reaction. Under suitable temperature and stirring conditions, the reaction continues. After the reaction is completed, the product is separated and purified by filtration, washing, drying and other steps. This method can take advantage of the stability of triethylamine hydrochloride to make the reaction easier to control and improve the purity and yield of the product.
Third, benzyl alcohol, triethylamine and hydrogen chloride gas are used as raw materials. First, benzyl alcohol is reacted with hydrogen chloride gas to form benzyl chloride. Benzyl alcohol is placed in a specific reaction device and dried hydrogen chloride gas is introduced. Under a certain temperature and catalyst action, the hydroxyl group of benzyl alcohol is replaced by chlorine atoms and converted into benzyl chloride. After benzyl chloride is formed, triethylamine is added, and the two further react to form triethylbenzyl ammonium chloride. Although the steps of this route are slightly complicated, the raw materials are commonly available and easy to obtain, and the reaction conditions of each step can be flexibly adjusted according to actual needs to achieve the purpose of optimizing production.
What are the precautions for 4-trifluoromethylbenzyl alcohol during storage and transportation?
Triolomethyl silicone is essential during storage and transportation.
It is flammable. When storing, be sure to choose a cool and well-ventilated place, away from fire and heat sources, to prevent the risk of ignition and explosion. The temperature of the warehouse should be controlled within an appropriate range, not too high. And it needs to be stored separately from oxidants, acids, etc., and must not be mixed with storage to prevent violent chemical reactions.
When transporting, the carrier must have corresponding qualifications. The packaging must be tight and firm, and flammable labels should be posted in accordance with regulations. Transportation vehicles should also be equipped with fire extinguishers. During driving, drivers should be cautious to avoid high temperature and exposure, and should not stop in densely populated places for a long time. In the event of an emergency situation, such as leakage, etc., appropriate measures must be taken immediately to evacuate the surrounding crowd, prevent open flames, and promptly report to the relevant departments.
Furthermore, whether it is storage or transportation, managers and operators must undergo professional training to be familiar with its hazard characteristics and emergency disposal methods. Storage areas and transportation tools should be equipped with leakage emergency treatment equipment and suitable containment materials to deal with sudden leakage situations in a timely manner and reduce damage hazards. In this way, the safety of trioleomethyl silicone during storage and transportation must be ensured to avoid disasters.