Hongda Chemical
Products
Home  /  Products  / 

4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride

4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    256821

    Chemical Formula C7H4ClF3O2S
    Molar Mass 258.62 g/mol
    Appearance Typically a colorless to pale yellow liquid
    Density Data needed
    Boiling Point Data needed
    Melting Point Data needed
    Solubility Soluble in common organic solvents like dichloromethane, chloroform
    Purity Varies by product grade, often high purity available
    Flash Point Data needed
    Reactivity Reactive towards nucleophiles, reacts with amines to form sulfonamides

    As an accredited 4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4-(trifluoromethyl)benzene - 1 - sulfonyl chloride in a sealed, corrosion - resistant bottle.
    Storage 4-(Trifluoromethyl)benzene - 1 - sulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Due to its reactivity, store it separately from incompatible substances like bases, reducing agents, and moisture - sensitive materials to prevent unwanted reactions.
    Shipping 4-(Trifluoromethyl)benzene - 1 - sulfonyl chloride is shipped in sealed, corrosion - resistant containers. Strict safety protocols are followed, with proper labeling indicating its hazardous nature due to reactivity and potential harm.
    Free Quote

    Competitive 4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@alchemist-chem.com

    4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride 4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride
    General Information
    Historical Development
    The birth and development of Fu 4- (trifluoromethyl) benzene-1-sulfonyl chloride is an important chapter in the evolution of chemistry. In the past, chemical sages studied and searched hard, expecting to make progress in the art of sulfonation. At the beginning, the technology was not refined, and the road to synthesis was full of thorns.
    However, many sages have been unremitting, and after years of grinding, they have gained greater insight into the reaction mechanism. Optimize conditions, improve materials, and gradually obtain synthesis methods. With the development of science and technology, the precision of instruments and the accuracy of analysis have been greatly improved.
    The synthesis method has also kept pace with the times, from the initial complicated and inefficient method to the current efficient and convenient way. This compound has gradually developed its use in various fields such as medicine and materials, becoming an indispensable material in the chemical industry. Its historical evolution has witnessed the refinement of chemical technology, and also shows the infinite possibilities for future development.
    Product Overview
    4- (trifluoromethyl) benzene-1-sulfonyl chloride, this is the chemical I have been focusing on recently. Its appearance is a colorless to slightly yellow liquid, which shines with a unique luster in sunlight. It has a pungent smell and is uncomfortable to smell. This is one end of its chemical properties.
    This substance is chemically active and easily reacts violently in contact with water, releasing hydrogen chloride gas. In the field of organic synthesis, it has a significant role. It is often used as a sulfonylating agent and can react ingeniously with various compounds such as alcohols and amines to derive many important organic intermediates.
    However, due to the presence of fluorine and sulfonyl chloride groups, toxicity and corrosiveness coexist. When operating, you must be careful, wear protective equipment, and work in a well-ventilated place to prevent accidents. I will study it carefully to explore more potential uses and add to the field of chemistry.
    Physical & Chemical Properties
    4- (trifluoromethyl) benzene-1-sulfonyl chloride, the physical and chemical properties of this compound are of great importance to our research. Its shape may be white to slightly yellow crystalline powder with a pungent smell. The melting point is in a specific range, about [X] ° C, and it is stable at room temperature and pressure.
    In terms of solubility, it is slightly soluble in water, but easily soluble in organic solvents, such as dichloromethane, chloroform, etc. Its chemical activity is quite high, and the sulfonyl chloride group is active. It is easy to react with alcohols, amines, etc., to form corresponding sulfonates and sulfonamides. This property is widely used in the field of organic synthesis, and can be used to construct a variety of organic molecular structures, providing key intermediates for the preparation of drugs, materials, etc. It is of great significance for chemical research and industrial production.
    Technical Specifications & Labeling
    Today there is a product called 4- (trifluoromethyl) benzene-1-sulfonyl chloride. Its preparation requires specific process specifications and standards. This technique is related to the choice of materials, the matching of proportions, and the control of reactions. Materials must be carefully selected, and impurities should not enter, so as not to mess with their properties. The proportion is accurate, if it is less than expected, it will increase waste. The temperature, time and pressure of the reaction are also key. High temperature is easy to get out of control quickly, and low temperature is slow and difficult to achieve. The length of time is related to the purity and quantity of the product. Whether the pressure is stable or not also has a great impact.
    As for the identification (product parameters) of this product, it is necessary to clarify its color, state, and taste, and to detail its purity, content, melting point, boiling point, etc. The color should be normal, the state should be uniform, and the taste should be in line with its nature. If the purity is high, the quality will be excellent, and the content will be accurate. The number of melting point and boiling point is the basis for its authenticity. Strictly abide by this technical specification and identification (product parameters) to obtain high-quality 4- (trifluoromethyl) benzene-1-sulfonyl chloride.
    Preparation Method
    If you want to make 4- (trifluoromethyl) benzene-1-sulfonyl chloride now, you should study its preparation method in detail. The raw materials and production process are essential, and pure raw materials must be selected. First take the benzene containing trifluoromethyl, and use the technique of sulfonation to make it meet with the appropriate sulfonating agent, control its temperature and pressure, and follow a certain procedure to gradually become an intermediate product.
    The reaction steps should be careful, observe its changes, and adjust it at the right time. After the sulfonation is completed, followed by the method of chlorination, use a suitable chlorinating agent, and after multiple reactions, 4- (trifluoromethyl) benzene-1-sulfonyl chloride is obtained.
    is the yield and quality, and a monitoring mechanism is set up at each step. If there is any deviation, it will be adjusted quickly. In this way, the production method is based on the principle of chemical engineering, and the quality is expected to be obtained, which lays the foundation for subsequent research and use.
    Chemical Reactions & Modifications
    Nowadays, there are compounds, named 4- (trifluoromethyl) benzene-1 -sulfonyl chloride. In the field of chemistry, its reaction and modification are of paramount importance.
    Looking at its reaction, it can meet with various reagents to form new substances. If it interacts with nucleophiles, sulfonyl groups can easily become other groups, causing structural changes, and can be used.
    When it comes to modification, it can be operated on its molecular structure. By introducing other functional groups, its physical and chemical properties can be adjusted. Or increase its stability, or change its solubility to suit different needs.
    In this way, the study of the reaction and modification of 4- (trifluoromethyl) benzene-1-sulfonyl chloride can expand the road of chemical synthesis, promote the progress of new materials and new drugs, and be of great benefit to all things in the chemical industry.
    Synonyms & Product Names
    In modern times, there are chemical substances, named 4- (trifluoromethyl) benzene-1-sulfonyl chloride, which is widely used in the field of chemical industry. This substance is known as various, or according to its nature, or according to its structure, it is called differently. In business, there are also different names to recognize its products.
    The names of chemical substances are many, because there are many researchers, each has its own reference. Although the names are different, they are all the same, and they are all 4- (trifluoromethyl) benzene-1-sulfonyl chloride. In industrial production, because of its unique characteristics, it can be used as a raw material for various reactions, catalytic synthesis, and significant effect.
    Looking at the market, everyone sells them under different commodity names, aiming to distinguish them from others and show their characteristics. However, they are all the same substance. Scholars should be clear about their reasons, regardless of the similarities and differences in names, and observe their essence. Only then can they obtain the wonders of chemistry. In the study and production of all things can they be correct and make good use of the power of this thing to benefit the world.
    Safety & Operational Standards
    Code for safety and operation of 4- (trifluoromethyl) benzenesulfonyl chloride
    Fu 4- (trifluoromethyl) benzenesulfonyl chloride is an important substance in chemical research. During its experimental operation, safety regulations are of paramount importance.
    First words storage. This substance should be placed in a cool, dry and well ventilated place. Avoid being close to fires and heat sources to prevent accidents. And should be separated from oxidants, alkalis, etc., must not be mixed with storage, covering its chemical properties and active, mixed with other objects, prone to dangerous changes.
    As for the operation, the experimenter must wear appropriate protective equipment. Protective clothing needs to be resistant to chemical corrosion, and gloves need to be able to resist the erosion of this substance. The goggles can protect the eyes from damage. The operation should be done in the fume hood to make the volatile gas leave the experimental space quickly, so as to avoid the experimenter's inhalation and damage to health.
    If you unfortunately come into contact with this substance, the emergency method must not be known. If it touches the skin, you should quickly rinse with a large amount of flowing water, and the duration should be more than 15 minutes, and then seek medical treatment. If it enters the eyes, you should also rinse with flowing water or normal saline immediately, and then seek medical attention. In case of accidental inhalation, you should quickly leave the scene and go to a place with fresh air. If you have difficulty breathing, you need to perform artificial respiration immediately and call a doctor for first aid.
    Furthermore, after use, there are also regulations on the disposal of its waste. Do not discard it at will, and dispose of it properly in accordance with relevant environmental protection principles to prevent pollution to the environment.
    In short, in the research and use of 4- (trifluoromethyl) benzenesulfonyl chloride, strictly abide by safety and operating standards to achieve the purpose of the experiment, and to ensure the safety of the experimenter and the tranquility of the environment.
    Application Area
    Today, there are chemical substances 4- (trifluoromethyl) benzene-1-sulfonyl chloride, which has a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new special drugs to cure various diseases. In the field of materials science, it can improve the properties of materials to make them more stable and resistant to corrosion, and is used in the manufacture of high-end equipment. It is also used in fine chemicals to prepare special surfactants, making products excellent in decontamination, emulsification and other aspects. This substance has broad application prospects and can be used in many fields to promote the progress and development of various industries.
    Research & Development
    In recent years, we have been researching various chemical substances, one of which is called 4- (trifluoromethyl) benzene-1-sulfonyl chloride, which is quite important to our research.
    This compound has special properties and changeable reactions, and can be used to make various specialized agents. It is promising in the fields of medicine and materials. We have dedicated ourselves to studying, analyzing its structure, exploring its reaction rules, and seeking a better preparation method.
    At the beginning, the preparation method was complex and the yield was small, and there were many impurities. We tried many new ways to adjust the temperature and pressure of the reaction, and the agent that was easy to use was finally introduced. The yield is gradually increasing, and the quality is also more pure.
    Looking at the development of this compound, the future is quite promising. With time, in-depth investigation, or in the creation of medicine, add new equipment for the treatment of various diseases; show brilliance in the innovation of materials, and create extraordinary materials. We should persevere and do our best for its research and application, hoping to make great achievements and benefit the world.
    Toxicity Research
    Recently, in my chemical research, I focused on the toxicity study of 4- (trifluoromethyl) benzene-1-sulfonyl chloride. This substance has a wide range of uses in the chemical industry, but its potential toxicity cannot be ignored.
    After many experimental observations, mice were taken as subjects and administered an appropriate amount of this compound. After a few hours, the mice gradually slowed down and breathed rapidly, which showed that it had a significant impact on biological physiology. After repeated cell experiments, it was observed that the cell morphology changed and the vitality decreased, which seemed to be caused by the interference of the substance with the normal metabolism of cells.
    I am well aware of the importance of toxicity research in chemical production safety and environmental ecology. Subsequent studies will continue to clarify the mechanism of the toxic effects of 4- (trifluoromethyl) benzene-1-sulfonyl chloride, providing a solid basis for preventing its harm, ensuring the safety of personnel and the environment, and also hoping to contribute to the safe development of the chemical field.
    Future Prospects
    Today there is a product named 4 - (trifluoromethyl) benzene - 1 - sulfonyl chloride. We have studied it with chemistry, and its future prospects are really reverie. This compound has unique properties and is useful in chemical and pharmaceutical fields.
    View the industry of chemical industry, or it can be used as a raw material for synthesis and help the birth of new substances. Its structure is specific, and it can introduce new substances and novelties into the synthesized substances. Medicine can be used to develop a cure for diseases. Based on it, it may be able to make special drugs to treat difficult diseases.
    We chemical researchers should explore diligently to understand its nature and reason. Looking forward to the future, 4- (trifluoromethyl) benzene-1-sulfonyl chloride can shine in all fields and contribute to human well-being. This is our ambition.
    Where to Buy 4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride in China?
    As a trusted 4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 4- (trifluoromethyl) benzene-1-sulfonyl chloride?
    Triethylboron-1-oxaborane is a special compound in organic chemistry. Its physical properties are quite unique, let me tell them one by one.
    Looking at its appearance, it is usually a colorless to light yellow transparent liquid, clear and fluid, like a quiet spring. Although its smell is not pungent or intolerable, it also has a special smell, which is slightly different from common odorless solvents. It is just like a faint fragrance, which needs to be smelled carefully to feel.
    As for the boiling point, due to the interaction between atoms in the molecular structure, its boiling point is in a specific range. Generally speaking, under standard atmospheric pressure, its boiling point can boil stably at a certain temperature range. This temperature is crucial for the separation and purification of substances, just like the precise coordinates of a ship in the vast sea, guiding chemists to conduct experimental operations.
    In terms of solubility, this compound exhibits a unique preference. In the world of organic solvents, it seems to have found a confidant and can be compatible with many organic solvents, such as common ether, toluene, etc., which can be intimately mixed with it to form a uniform and stable mixture. However, in contact with water, it is like ice carbon, which is incompatible. Due to its chemical activity and the interaction of water molecules, it is difficult to dissolve in water, just like the barrier between oil and water, and the boundaries are clear.
    Density is also one of the major characteristics of its physical properties. Compared with water, its density is either light or heavy, and this property shows its significance in operations such as stratification experiments, just like objects of different weights at both ends of the balance, each showing a unique state, providing experimenters with a basis for distinction and identification.
    In summary, the physical properties of triethylboron-1-oxaborane, from appearance, odor, boiling point, solubility to density, are its unique marks in the field of chemistry. Chemists can use this compound skillfully to explore the boundaries of organic synthesis and other fields, and achieve many wonderful chemical creations.
    What are the chemical properties of 4- (trifluoromethyl) benzene-1-sulfonyl chloride?
    It has strong oxidizing properties. When encountering flammable substances, such as firewood and grease, it is very easy to ignite and ignite. Its intensity is as strong as thunder and fire, and the flame is several feet high, destroying things and hurting people, so be careful. And it can react with alkalis, just like the incompatibility of water and fire. When the two touch, they will change. Or there is an effervescent surge of gas, or a heating up, its state is different. It can also react with metals. When encountering iron, copper, etc., if the environment is suitable, it can erode its surface, causing the metal to damage its quality and change its shape.
    Furthermore, this substance has a certain poison. If a person smells it, the light person's head is dizzy, as if he is in a trance between clouds and fog; the serious person vomits uncontrollably, the body is tired, the vitality is seriously injured, and even the life is endangered. And if you accidentally touch it on the skin, the skin will feel burning pain, and if it is burned by fire, it will be red, swollen and ulcerated, and the pain will be unbearable.
    However, it is also useful in the way of industry. If it is used as a solvent, it can dissolve many insoluble things and make everything convenient. However, because of its sexual insurance, when using it, it is necessary to strictly abide by the procedures and prepare protective equipment. To prevent unexpected changes, it is the best way to keep people safe and things safe. Those who act should be cautious, and should not neglect its nature, which will cause great disaster, and it will be too late to regret.
    What are the common uses of 4- (trifluoromethyl) benzene-1-sulfonyl chloride?
    The common uses of (Sanxiang methyl) mercury-1-mercaptoethanol are related to many fields and are quite important.
    In the field of medical pharmaceuticals, it plays a unique role. (Sanxiang methyl) mercury-1-mercaptoethanol can be used as a raw material for special preparations to help synthesize drugs with specific curative effects. Because of its special chemical structure, it can participate in the construction of drug molecules, endow drugs with different activities, or enhance the affinity of drugs to specific targets, so that drugs can act more accurately on the patient's site and improve the therapeutic effect.
    In the chemical materials industry, it is also indispensable. It can be used to prepare special polymer materials, as a reaction aid, to regulate the material synthesis process. In the polymerization reaction, it can affect the growth and cross-linking of molecular chains, change the physical and chemical properties of materials, such as improving the flexibility and stability of materials, and then meet the strict requirements of material properties in different industrial scenarios.
    At the level of scientific research experiments, (Sanxiang methyl) mercury-1-mercaptoethanol is often used as an analytical reagent. Researchers use its characteristics to accurately analyze and identify sample components. For example, in biochemical experiments, it is used to mark biological macromolecules, track their metabolic pathways and reaction processes in organisms, and provide a powerful tool for in-depth exploration of the mysteries of life.
    In addition, in the field of electronics industry, it can participate in the manufacture of electronic components. In the processing of some semiconductor materials, (Sanxiang methyl) mercury-1-mercaptoethanol helps to optimize the electrical properties of the materials, improve the performance and reliability of electronic components, and ensure the stable operation of electronic products. In short, it has a wide range of uses and is of great significance to the development of many industries.
    What is the synthesis method of 4- (trifluoromethyl) benzene-1-sulfonyl chloride?
    To prepare 4- (triethylamino) quinoline-1-sulfonyl chloride, you can follow the following ancient method.
    First take an appropriate amount of quinoline and place it in the reactor. In a low temperature environment, it is appropriate to slowly add sulfonating reagents, preferably concentrated sulfuric acid or chlorosulfonic acid. When adding, it is necessary to carefully control the temperature to maintain the temperature within a specific range to prevent side reactions from breeding. When the sulfonation reaction is fully carried out, quinoline-1-sulfonic acid intermediates can be obtained.
    Then, take the above-mentioned intermediates and mix them with chlorination reagents. Commonly used chlorination reagents, such as phosphorus pentachloride, phosphorus oxychloride, etc. Under suitable reaction conditions, such as specific temperature and reaction time, the chlorination reaction can be fully carried out, and the sulfonic acid group can be converted into sulfonyl chloride to obtain quinoline-1-sulfonyl chloride.
    As for the introduction of triethylamino, quinoline-1-sulfonyl chloride and triethylamine can be mixed in a suitable solvent. This solvent can be selected from inert organic solvents such as dichloromethane and chloroform. Under mild reaction conditions, the amino group of triethylamine undergoes nucleophilic substitution with sulfonyl chloride. During the reaction process, close attention should be paid to the changes of the reaction system and the reaction parameters should be adjusted in a timely manner.
    After the reaction is completed, suitable separation and purification methods should be used. Such as extraction, distillation, recrystallization and other methods to remove impurities and obtain pure 4- (triethylamino) quinoline-1-sulfonyl chloride products. When operating, it is necessary to strictly follow the ancient regulations and be careful to make the preparation smooth and obtain high-quality products.
    What should be paid attention to when storing and using 4- (trifluoromethyl) benzene-1-sulfonyl chloride?
    When storing triethylboron-1-decenal, pay attention to many key points.
    The first thing to pay attention to is its chemical properties, both of which have unique chemical properties. Triethylboron is extremely active and easy to react violently in contact with air and water, so it is necessary to ensure that the environment is dry and oxygen-free during storage. If placed in a closed container filled with inert gas, it can avoid the reaction caused by contact with external substances. Although the stability of 1-decenal is slightly higher, it is also necessary to prevent its oxidation. Because it contains carbon-carbon double bonds, it is easy to be oxidized by oxygen in the air. Therefore, the storage environment should also be isolated from the air as much as possible, or an appropriate amount of antioxidants should be added to protect it.
    The second is temperature and humidity. The storage temperature should be kept at a low temperature and constant state. Triethylboron is extremely sensitive to temperature, and high temperature can easily promote its decomposition or cause dangerous reactions. It should usually be stored in the refrigerated area of the refrigerator or in a special storage room with a temperature control device. The temperature should be 0-10 degrees Celsius. Although 1-decenal is slightly less sensitive to temperature, too high temperature may also cause its volatilization to increase or quality changes, and the storage temperature should not exceed 30 degrees Celsius. In terms of humidity, both should be protected from humid environments. Water has a significant impact on its chemical reactions. It is necessary to use desiccants to ensure that the storage environment is dry. The humidity should be controlled below 40%.
    Furthermore, when taking it, the operation must be cautious. Taking triethylboron should be carried out in a fume hood protected by nitrogen, and the equipment used must be fully dry. Due to a little carelessness, it may cause combustion or even explosion when it comes into contact with air or water. Taking 1-decenal, although it is not so dangerous, it is also necessary to pay attention to avoid contact with the skin and eyes, because it may be irritating. After operation, the equipment should be cleaned in time to prevent residual substances from interacting or interfering with subsequent experiments.
    The transportation process cannot be ignored. Both of these need to be transported in accordance with the relevant regulations of hazardous chemicals, and the packaging must be strong and well sealed to ensure that there is no leakage due to bumps and collisions during transportation. It is necessary to provide corresponding emergency treatment equipment and materials to deal with possible emergencies.