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4-(Trifluoromethyl)Benzene-1-Carbothioamide

4-(Trifluoromethyl)Benzene-1-Carbothioamide

Hongda Chemical

Specifications

HS Code

862766

Chemical Formula C8H6F3NS
Molecular Weight 203.20
Appearance Solid (Typical)
Melting Point 135 - 139 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Purity Typically high - purity grades available, e.g., 95%+
Odor May have a characteristic sulfur - containing odor

As an accredited 4-(Trifluoromethyl)Benzene-1-Carbothioamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4-(trifluoromethyl)benzene - 1 - carbothioamide in a sealed, chemical - resistant bag.
Storage 4-(Trifluoromethyl)benzene - 1 - carbothioamide should be stored in a cool, dry place, away from direct sunlight. Keep it in a well - sealed container to prevent moisture and air exposure, which could potentially lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents or bases, in a dedicated chemical storage area for safety.
Shipping 4-(Trifluoromethyl)benzene - 1 - carbothioamide is shipped in sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring secure transport to prevent leakage and potential environmental or safety risks.
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4-(Trifluoromethyl)Benzene-1-Carbothioamide 4-(Trifluoromethyl)Benzene-1-Carbothioamide
General Information
Historical Development
4- (trifluoromethyl) benzolamide, the development process of this compound is quite descriptive. In the past, at the beginning of chemical research, many substances were still to be explored. At that time, scholars were dedicated to the study of various organic compounds.
During the long scientific research process, the exploration of fluorine-containing compounds gradually emerged. Due to the unique properties of fluorine, compounds are endowed with unique characteristics. After unremitting experiments and research, 4- (trifluoromethyl) benzolamide was successfully synthesized.
At the beginning of its synthesis, the conditions were harsh and the yield was not ideal. However, scientific researchers were not discouraged and repeatedly adjusted the reaction conditions to optimize the synthesis path. With the passage of time, the technology is becoming more and more mature, the synthesis of this compound is more and more efficient, the application field is also expanding, and it has emerged in many aspects such as medicine and materials, adding a strong color to the development of the chemical field.
Product Overview
Today, there is a product called 4 - (trifluoromethyl) benzosulfamide. Its shape is unique and its properties are extraordinary. Looking at its structure, trifluoromethyl is attached to the benzene ring, and the thiamide group is connected to it. The structure is exquisite and unique.
This product is used in various fields of chemical industry and has a wide range of uses. It can be used as a synthetic agent, participating in various organic reactions, and is a key component in the creation of new materials and drugs. In the process of scientific research, it helps chemists explore the details and expand the boundaries of cognition.
When preparing, it is necessary to follow precise methods, and the temperature control, pressure regulation, and formulation need to be exquisite to obtain its pure product. Although the preparation is not easy, its effectiveness is significant, and it is a treasure of chemical research with broad prospects, which is shared by the academic community and the industry.
Physical & Chemical Properties
The physical and chemical properties of 4- (trifluoromethyl) benzethanolamide are important for research. The form of this substance is either solid at room temperature or white crystalline powder, fine and uniform in quality. Its odor may have a specific sulfur amide smell.
When it comes to solubility, it may have a certain solubility in organic solvents, such as ethanol and acetone. However, in water, the solubility may be low, due to the hydrophobicity of trifluoromethyl in the molecular structure. Its melting point, which has been carefully determined, or falls in a specific temperature range, is the key parameter for identifying its purity and characteristics. And its chemical stability also needs to be considered. Under different acid-base environments, the structure may change to varying degrees, which is something that our chemical researchers should carefully investigate in order to understand its essence and make good use of it.
Technical Specifications & Labeling
Today there is a product called 4 - (trifluoromethyl) benzolamide. To clarify its technical specifications and labels (product parameters), I will investigate it in detail.
This substance should be pure and free of impurities and uniform in color. Its purity is crucial, it should reach a very high standard, and the impurity content must be minimal. As for the physical parameters such as melting point and boiling point, it is also precisely defined. The melting point should be in a specific range, and the boiling point must also conform to the established value to prove its quality.
In terms of marking, the name should be clearly engraved on the package, indicating key parameters such as composition, purity, etc. To prevent confusion and misjudgment by those who use it. Technical specifications and logos are the bedrock of a product, and are crucial to its quality and safety. Only by strictly observing them can we ensure that they are properly applied in various fields and benefit the world.
Preparation Method
In order to make 4 - (trifluoromethyl) benzothiamide, it is necessary to prepare its raw materials first. Start with halogenated aromatics containing trifluoromethyl and sulfur-containing nucleophiles. Take an appropriate amount of 4 - (trifluoromethyl) halogenated benzene, dissolve it with thioacetamide and other reagents in a suitable organic solvent, such as N, N - dimethylformamide.
When reacting, control the temperature in an appropriate range, about 60 to 80 degrees Celsius, to promote the nucleophilic substitution reaction to proceed smoothly. This step requires about a few hours, and observe it closely during the period.
After the reaction is completed, use common post-treatment methods, such as extraction, washing, drying, to remove impurities. Pure 4 - (trifluoromethyl) benzolamide was obtained by vacuum distillation or column chromatography. This method is easy to obtain raw materials, simple steps, and reproducible, which can be used for the preparation of this product.
Chemical Reactions & Modifications
We have studied the reaction properties of benzethylthiamide. The reaction properties of benzethylthiamide are either nuclear substitution or nuclear migration. Trifluoromethyl has the property of absorbency, which affects the cloud density of benzene, so that the reaction properties of benzene and benzene are very common.
For the synthesis of benzene, it is often necessary to prepare suitable products. For example, the reaction properties of thioamide need to be controlled, and the degree of resistance can be obtained. Its chemical properties are also very special. Due to the characteristics of fluorine atoms, this material has a phase quality, and it has special solubility for some solubility. And because of its properties, it can generate and interact with multiple compounds, either forming or forming, which is the focus of research, and it is necessary to understand its reverse properties in order to realize the wonders of synthesis.
Synonyms & Product Names
Today there is a product called 4 - (trifluoromethyl) benzolamide. This product is widely used in the field of chemical industry. Its synonymous name is also known. Or trifluoromethylbenzolamide, which is a change of title, but in fact refers to the same thing.
The name of the commercial product also varies from time to place. Or there are people who call it "Tefluromethylbenzamide", although the words are different, the quality they refer to is this 4 - (trifluoromethyl) benzolamide. This is due to industry customs and paging, so various synonymous names and commercial names have been derived. For those of us who study this object, no matter what it is called, we should clarify what it means, in order to study its essence, explore its performance, and seek the path of chemical engineering, which will make progress and pave the way for various applications.
Safety & Operational Standards
4- (trifluoromethyl) benzosulfamide is a chemical product that we have painstakingly studied. It needs to be paid great attention to in the field of safe production and standardized operation.
In the first part of the preparation process, pure and high-quality raw materials must be selected, and the proportion of each reactant must be precisely controlled to achieve the best reaction effect. The environment, temperature and humidity between operations should be maintained in a suitable range. Do not overheat, overdry or wet, so as not to affect the reaction process. The reaction equipment must be regularly overhauled to ensure that it is well sealed and there is no risk of leakage.
In accordance with the operating specifications, all personnel involved in the preparation of this product must wear complete protective equipment, such as gas masks, chemical-resistant protective clothing and gloves, etc., to prevent contact or inhalation of harmful ingredients. During the material transfer process, the action should be steady and precise to avoid spilling and dripping. During the reaction, closely monitor various parameters, such as temperature, pressure and reaction time. If there is any abnormality, immediately dispose of it according to the regulations.
Product storage should not be underestimated. Choose a dry, cool and well-ventilated place, away from fire and heat sources, and store it in categories. It is strictly forbidden to mix with oxidizing substances to prevent accidents. During transportation, ensure that the packaging is firm, the identification is clear, follow the relevant transportation regulations, and escort carefully.
When disposing of waste, it is strictly in accordance with environmental protection requirements. After proper disposal, it can be discharged or disposed of. It must not be discarded at will, causing environmental pollution.
In this way, during the whole life cycle of 4- (trifluoromethyl) benzolamide, strict adherence to safety and operating standards can ensure the well-being of personnel and the environment, and promote the steady progress of the chemical industry.
Application Area
In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize special drugs and cure various diseases. In the field of material science, with its unique chemical properties, it can improve material properties, make materials have better stability and corrosion resistance, and be used in high-end equipment. And in agricultural and chemical industry, it can be used to create new pesticides, enhance the effect of insecticide and sterilization, and protect crop growth. All of these all highlight the important value of 4- (trifluoromethyl) benzolamide in many fields. Its application prospect is really wide and boundless. We need to explore it in depth to make the best use of it.
Research & Development
The rise of modern chemistry is to study the properties of substances and seek new materials for the benefit of the world. Today there is 4- (trifluoromethyl) benzosulfamide. In the way of research and progress, our generation will study it in detail.
Its preparation requires precise control of various ends, such as the mixing of materials, the degree of temperature and pressure. Observe its reaction mechanism, and if it can be discerned, the yield can be increased. The method of the past may not be good, but now it should be innovated for the best.
On its properties, it may have potential in pharmacology. The interaction between it and biomolecules can be explored, hoping to open up a new way for the creation of medicine. And in the field of materials, its characteristics may inspire the research of new materials and help the progress of science and technology.
We chemical researchers should make every effort to investigate the secrets of this thing, so as to promote it in the process of research and progress, for the well-being of the world, and create immeasurable work.
Toxicity Research
Recently, I have been studying the toxicants in the room, focusing on the substance 4- (trifluoromethyl) benzosulfamide. Examine its properties in detail and find out its toxicology. This compound may have potential harm. After repeated tests, analyzing its components and observing its reaction, it can be known that under specific conditions, it can cause biochemical changes and affect the surrounding body. Although it does not cause major harm to the present, its toxicity should not be underestimated. If it enters the organism, it will disrupt its physiological order, damage the organs, and hinder its function. Therefore, studying the toxicity of this substance is related to the health of the living being, and it must not be slack. Be sure to investigate in detail, clarify the path of its poison, and prevent its abuse from becoming a disaster, so as to keep the world quiet and peaceful.
Future Prospects
Today, there is a product named 4- (trifluoromethyl) benzosulfamide. Looking at this substance, its characteristics are specific, and it has great potential in the field of chemical industry.
Future development is expected to find new ways in the development of medicine. Because of its unique structure, it may be helpful for drugs for specific diseases and benefit patients.
In the research and development of materials, there are also opportunities. It may be possible to improve the properties of materials, making them more tough and durable, and used in various fields, such as aerospace, electronics, etc.
Furthermore, in environmental governance, there may be wonderful uses. After research, it may be able to find a way to purify the environment and solve the current pollution dilemma.
The future of this material is like the beginning of the stars. Although it is not completely bright, it has already revealed its light. In the future, it can be expected to shine brightly and be used by the world.
Where to Buy 4-(Trifluoromethyl)Benzene-1-Carbothioamide in China?
As a trusted 4-(Trifluoromethyl)Benzene-1-Carbothioamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-(Trifluoromethyl)Benzene-1-Carbothioamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4- (trifluoromethyl) benzothiamide?
(Triethyl) silicoethyl phosphate borate, which is mainly used in the field of synthesis.
This compound can be used in the field of synthesis. In chemical research, due to its special chemical properties, it can be used as an important medium. For example, in some processes with specific bioactive molecules, (triethyl) silicoethyl phosphate borate can be used as a reverse step. It helps to form functional molecules with specific functions in the chemical molecules, and can provide the required biological activities of the chemical, such as antibacterial, antiviral and other effects.
In terms of material science, it also has outstanding performance. It can be used in the development of new chemical materials, which can improve the properties of materials. For example, adding this material in the synthesis of some polymer materials can improve the quality, resistance and mechanical properties of the material. It can be modified, combined or physical, and the polymer group interacts, so that the integrity of the material can be improved, and the application of the material in high-demand fields such as aerospace and sub-devices can be expanded.
In addition, in the chemical catalyst domain, (triethyl) silicoethyl phosphate borate can also be used. It can be used as a preparation or as a catalyst, and the gold catalyst can jointly catalyze the reaction. It can improve the activity and performance of the catalyst, promote the reaction to be more efficient and more efficient, and improve the reaction rate and the degree of the product. It is of great significance for the transformation of many important reactions in the chemical industry.
What are the physical properties of 4- (trifluoromethyl) benzothiamide
(Sanxiang methyl) silicon-methyl-aluminum-borane is a strange material with many unique physical properties.
Its texture is light, and its specific gravity is lower than that of ordinary metals. It is like the feathers of flying swallows, and it can carry unique energy between lightness. This lightness makes it lightweight, and it plays an important role in specific scenes. In places with strict requirements for weight, it shows extraordinary value.
Excellent thermal stability, just like the rock that has not been destroyed by fire for a long time. In high temperature environments, it can also maintain its inherent structure and performance without being disturbed by hot heat. Therefore, it can play a key role in high temperature operations, such as metallurgy, kilns, etc., to ensure stable operation.
Excellent electrical insulation, like an invisible barrier, can effectively block the current. In the electrical field, it can be used to manufacture insulating components to ensure that the current flows according to the established path, avoid hidden dangers such as leakage, and build a strong defense line for the safe and stable operation of electrical equipment.
Chemical stability is also commendable, just like the hermit who is unmoved in the hustle and bustle of the world. In the face of the erosion of many chemical substances, it can be as stable as Mount Tai and is not easy to react with it. This makes it able to maintain its own characteristics for a long time and prolong the service life in complex chemical environments such as chemical industry and oceans.
Furthermore, its flexibility is also remarkable, unlike ordinary brittle materials, which are easy to fold. It can be moderately bent like wicker without breaking, and in some manufacturing scenarios where material flexibility is required, it can skillfully adapt to the needs of complex shapes, showing different advantages.
(Sanxiang methyl) The unique physical properties of silicon-methyl-aluminum-borane make it a shining star in the field of materials, shining brightly in many industries and has broad application prospects.
What are the chemical properties of 4- (trifluoromethyl) benzothiamide?
(Triethyl) silicoethyl phosphate borate, its chemical properties are very special. This substance also has the characteristics of silicon, phosphorus and boron elements, and the interaction is exquisite.
As far as its anti-activity is concerned, because it contains silicon groups, it has a certain degree of stability, but under specific conditions, it can also have many anti-reactions. The sub-cloud of silicon atoms makes it capable of interacting with nuclei or molecules, leading to substitution, addition, etc.
The phosphorus-based part gives this substance good water-based properties. The phosphate esters can be different in aqueous solution, depending on the acidity of the environment. This property makes it an important mediator in some interfacial reactions or catalytic processes.
Furthermore, the existence of boron esters adds to its chemical properties. The lack of molecular properties of boron atoms makes the compounds easy to form complexes of molecules or molecules rich in molecules or molecules, and many catalytic synthesis processes. In some chemical reactions and carbon-carbon reactions, it can be used as an efficient catalyst or activation.
In addition, (triethyl) silethyl phosphate borate esters also exhibit certain tolerance under high or oxidation environments. However, the degree of oxidation or oxidation can still break down their molecules, leading to decomposition or oxidation reactions. Its versatility makes it a huge resource in the fields of materials science, synthesis, etc., which can be used for research and development, and provide rich material ideas.
What are the synthesis methods of 4- (trifluoromethyl) benzothiamide?
To prepare tetra- (triethylamino) benzyl sulfonate, there are various methods. First, start with benzyl alcohol and go through halogenation to obtain halogenated benzyl. Make halogenated benzyl meet triethylamine to form a quaternary ammonium salt. Then make this salt and the alkali metal salt of sulfonic acid react with nucleophilic substitution in a suitable solvent to obtain the target product. In this way, the halogenation step, the halogenating agent can be selected from thionyl chloride, phosphorus trihalide, etc. The reaction conditions are mild and the yield can be observed.
Second, benzaldehyde is used as the starting material. First, benzyl alcohol is reduced to obtain benzyl alcohol. For example, sodium borohydride is used as a reducing agent and reacts in an alcohol solvent, which is convenient to operate. Tetra- (triethylamino) benzyl sulfonate was obtained by halogenation, formation of quaternary ammonium salt and nucleophilic substitution. This starting material is easy to obtain, and the cost may be advantageous.
Or, it is based on p-toluenesulfonate. Make it and the nucleophilic reagent containing triethylamino, under appropriate conditions, directly carry out nucleophilic substitution. This step is simple, but the activity of the nucleophilic reagent and the reaction conditions are strictly controlled. During the reaction, the choice of solvent, the control of temperature, and the degree of reaction time are all related to the yield and purity of the product.
The methods for preparing tetra- (triethylamino) benzyl sulfonate vary, and each has its own advantages and disadvantages. The experimenter should choose the suitable one according to the availability of raw materials, cost considerations, yield and difficulty of operation, so as to prepare the compound.
What are the precautions for the storage and transportation of 4- (trifluoromethyl) benzothiamide?
In the storage and storage of (triethyl) silethyl phosphate, the following things need to be paid attention to:
First, the storage is especially important.
The storage is especially important. This is because if the material is in a high environment, or the quality is not good due to poor communication, it is easy to change the performance. The temperature of the room should be controlled at the appropriate level to prevent it from being affected by the temperature wave. It is necessary not to mix oxidation, acid and other substances, because the (triethyl) silethyl phosphate may cause severe reactions, or even cause serious accidents such as explosions.
Second, it is not necessary to pack. The package must be sealed, so there is no risk of leakage. If there is a problem of broken or poor sealing, on the one hand, it may cause (triethyl) silicoethyl phosphate to fail, not causing material loss, and possibly causing pollution to the empty room; on the other hand, external moisture, oxygen and other substances may also invade, affecting its qualitative.
Third, the problem should not be small. This is to prevent accidents such as leakage in the event of leakage on the way, which can be quickly dealt with and reduce the degree of harm. On the way, it is necessary to ensure that the container does not leak, does not collapse, does not fall, and does not leak. Avoid oxidation, acid and other mixing, in order to prevent the process due to earthquake, friction and other factors. At the same time, it is also necessary to make reasonable use of the road to avoid sensitive areas such as densely populated areas and water sources, so as to avoid accidents and minimize the harm to people and the environment.