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What are the main uses of 4- (trifluoromethoxy) iodobenzene?
There are two main uses for (triamino) arsenic. First, in the field of medicine, people in the past used to be sick. Because of the poison of arsenic, it may be effective in some diseases. In ancient times, it was used to treat scabies, scabs, and other diseases. For example, in the "Materia Medica", arsenic "is used to remove the poison, meat, fetuses, hemorrhoids", but it has been involved in the field of medicine. However, due to the severe toxicity, it needs to be used with caution.
Second, it is also used in medicine. In ancient medicine, the Dan family wanted to produce an elixir of immortality, and often used various substances, including arsenic, into medicine. They are special, which can reduce its toxicity and make it have magical effects. As described in Ge Hong's "Baopuzi", there may be arsenic in it. However, the things obtained from the pill contain more poison, which not only cannot be produced, but also kills people. Therefore, (triamino) arsenic was mainly used in ancient times, but also because of its toxicity.
What are the synthesis methods of 4- (trifluoromethoxy) iodobenzene?
There are several methods for the synthesis of triethoxysilane, which are described in detail below.
One is the direct reaction of silicon powder with ethanol. The silicon powder is placed in a special reactor, ethanol vapor is introduced, and a suitable catalyst is added, such as a copper catalyst. Under specific temperature and pressure conditions, the silicon powder reacts chemically with ethanol, and the reaction formula is roughly as follows: $Si + 3C_ {2} H_ {5} OH\ stackrel {catalyst} {\ longrightarrow} (C_ {2} H_ {5} O) _ {3} SiH +\ frac {3} {2} H_ {2} $. This reaction requires fine regulation of temperature and pressure. If the temperature is too high, there will be many side reactions, which will reduce the purity of the product. Improper pressure also affects the reaction rate and conversion rate. However, its advantages are that the raw materials are easy to obtain, the cost is relatively low, and the process steps are not very complicated.
The second is the method of using chlorosilane as a raw material. First take chlorosilane, such as trichlorosilane, and carry out an alcoholysis reaction with ethanol. In this process, the chlorine atom of trichlorosilane is gradually replaced by an ethoxy group. During the reaction, it is often necessary to add an acid binding agent to absorb the generated hydrogen chloride, so that the reaction proceeds in the direction of generating triethoxysilane. The reaction is roughly as follows: $SiHCl_ {3} + 3C_ {2} H_ {5} OH\ stackrel {acid binding agent} {\ longrightarrow} (C_ {2} H_ {5} O) _ {3} SiH + 3HCl $. The advantages of this method are that the reaction is relatively fast and the product purity is quite high. However, chlorosilane is highly corrosive, which requires strict equipment materials, and the use of acid binding agent also increases the cost and difficulty of post-treatment.
The third is the silicon ester exchange method. Select a suitable silicon ester and perform ester exchange reaction with ethanol under the action of catalyst. For example, by reacting tetraethoxysilane with ethanol, triethoxysilane can be obtained by adjusting the ratio of reactants and reaction conditions. The key to this reaction lies in the choice of catalyst and the precise control of reaction conditions. Its advantages are that the reaction conditions are relatively mild, the equipment requirements are slightly lower, and the product separation is more convenient. However, the raw material tetraethoxysilane is expensive, resulting in increased costs.
What are the physical properties of 4- (trifluoromethoxy) iodobenzene?
The physical properties of triethoxysilane are particularly important. Under normal conditions, this substance is mostly colorless and transparent, and has fluidity. Its appearance is clear, just like clear water, without variegation or turbidity.
In terms of its smell, it is slightly fragrant, but it is not rich and pungent, and ordinary people can tolerate it. Its density is slightly lighter than that of water, and it can float on the water surface when placed in water. This characteristic has a significant impact on the mixing and stratification of substances in many process operations.
In addition, the boiling point of triethoxysilane is also an important physical property. Its boiling point is moderate, and at this temperature, the substance changes from liquid to gaseous state. This temperature characteristic is a key consideration in chemical processes such as separation and purification. Heating to near the boiling point can vaporize triethoxysilane and separate it from other substances, so as to achieve the purpose of purification.
In terms of solubility, triethoxysilane can be soluble in many organic solvents, such as ethanol and ether. This solubility makes it suitable for organic synthesis. It can be uniformly mixed with many organic compounds and participate in various chemical reactions, greatly expanding its application scope.
In addition, the flash point of triethoxysilane cannot be ignored. It has certain flammability, and it may burn in case of open flames, hot topics, etc. Therefore, during storage, transportation and use, it is necessary to strictly abide by fire safety regulations to ensure the safety of the operating environment.
Looking at its physical properties, each one is closely related to practical applications, and is an indispensable basis in many fields such as chemical production and material preparation. Artisans, warlocks, etc. understand its characteristics and make good use of them to create all kinds of delicate things.
What are the precautions for 4- (trifluoromethoxy) iodobenzene during storage and transportation?
Tris (triethoxy) silane needs to be paid attention to many matters during storage and transportation.
One is storage. This substance should be stored in a cool and ventilated warehouse. Because the temperature is too high, it is easy to cause its volatilization to accelerate, and even cause danger, so avoid fire and heat sources. The warehouse temperature should be controlled within an appropriate range, not too high. And keep the warehouse dry, because it is easy to react in contact with water and affects the quality, so it must be moisture-proof. At the same time, it needs to be stored separately from oxidants, acids, alkalis, etc., to avoid chemical reactions caused by mixed storage. When storing, it should be sealed to prevent leakage and deterioration.
The second is transportation. Before transportation, ensure that the packaging is complete and well sealed to prevent leakage during transportation. During transportation, keep away from fire and heat sources to avoid exposure to the sun. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If the transportation process encounters high temperature weather, appropriate cooling measures should be taken. Moreover, during transportation, do not mix with oxidants, acids, alkalis and other items to prevent dangerous interactions. Handle with care during loading and unloading to prevent damage to packaging containers and avoid silane leakage.
Follow the above storage and transportation precautions to ensure the safety of tri (triethoxy) silane during storage and transportation, avoid accidents, and ensure the safety of personnel and the environment.
What is the approximate market price of 4- (trifluoromethoxy) iodobenzene?
Today, the price of (trihydroxyethyl) theophylline in the market is difficult to determine, due to a variety of reasons.
First, it is related to the quality of this medicine. Those who are high-quality, have excellent efficacy, excellent raw materials and good craftsmanship, and their price will be high; if the quality is normal, the price may be slightly lower. If you choose high-purity raw materials, through exquisite processing methods, the cost will be high, and the price will also rise.
Second, the supply and demand of the city will determine the price. If the medical community has a strong demand for this medicine, and the output is limited, the demand will exceed the supply, and the price will rise; conversely, if there is too much production and too little demand, the supply will exceed the demand, and the price will decline.
Third, pharmaceutical companies and distribution routes also have an impact. Large factories have a long reputation, and the brand is effective, and their drug prices may be higher than those of small factories. And the distribution links are simple and geographical distance, which can cause price changes. If it changes hands through multiple layers, the price may increase; in remote places, the transportation cost is high, and the price is also affected by it.
Fourth, the regulations of government orders and tax policies are related to drug prices. If the government strictly controls production standards, the compliance cost of pharmaceutical companies will increase, and the price may increase; the increase or decrease in taxes can also cause drug prices to fluctuate.
In summary, the market price of (trihydroxyethyl) theophylline may fluctuate between tens of yuan and hundreds of yuan. For ordinary quality, each dose may cost tens of yuan; if the quality is outstanding and the brand is well-known, each dose may cost more than 100 yuan, or even hundreds of yuan. However, this is only a rough estimate, and the actual price shall be subject to the real-time market conditions.