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4-(Trifluoromethoxy)Fluorobenzene

4-(Trifluoromethoxy)Fluorobenzene

Hongda Chemical

Specifications

HS Code

874752

Chemical Formula C7H4F4O
Molecular Weight 180.1
Appearance Colorless liquid
Boiling Point 115 - 117 °C
Density 1.32 g/cm³
Flash Point 21 °C
Solubility In Water Insoluble
Refractive Index 1.388

As an accredited 4-(Trifluoromethoxy)Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - mL glass bottle containing 4-(trifluoromethoxy)fluorobenzene for chemical packaging.
Storage 4-(Trifluoromethoxy)fluorobenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Use storage cabinets made of materials resistant to its corrosive nature, following local safety regulations for handling such chemicals.
Shipping 4-(Trifluoromethoxy)fluorobenzene is shipped in specialized, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring safe transit to prevent leakage and environmental or safety risks.
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4-(Trifluoromethoxy)Fluorobenzene 4-(Trifluoromethoxy)Fluorobenzene
General Information
Historical Development
"The History of Tetra- (Trifluoromethoxy) Fluorobenzene"
Tetra- (trifluoromethoxy) fluorobenzene is also an organic compound. Tracing back to its origin, at the beginning, the chemical sages worked hard in the field of organic synthesis. At that time, science and technology were not as prosperous as they are today, and the road to exploration was full of thorns.
However, the masters adhered to their determination, and after repeated experiments, they finally obtained the method of synthesizing this compound. At first, the synthesis technique was cumbersome and the yield was not abundant. Later, with the passage of time, the chemical technique became more and more exquisite. Zhu Xian carefully studied the reaction conditions, improved the reagents, and optimized the process. Today, the synthesis method has gradually matured, and the yield has also increased significantly. From its difficult creation in the past to its stable production today, the development of this compound is truly a glorious page in the history of chemistry, witnessing the crystallization of wisdom and perseverance of various sages.
Product Overview
Description of 4- (trifluoromethoxy) fluorobenzene
4- (trifluoromethoxy) fluorobenzene, which is a valuable compound in organic synthesis. Its properties are colorless and transparent liquids with a special odor and good solubility in organic solvents.
In terms of its structure, the fluorine atom on the benzene ring is cleverly connected to the trifluoromethoxy group, giving it unique physical and chemical properties. This structural feature gives it significant properties in terms of electronic effects and shows different activities in many chemical reactions.
In the field of synthesis, 4- (trifluoromethoxy) fluorobenzene is often used as a key intermediate. With its special structure, it can participate in a variety of reactions, such as nucleophilic substitution, coupling reactions, etc., to help synthesize complex and functional organic molecules. It has important applications in pharmaceutical research and development, materials science and other fields. The cleverly designed reaction path can convert it into biologically active drug molecules, or endow materials with unique properties, such as excellent stability and electrical properties.
4- (trifluoromethoxy) fluorobenzene is an indispensable and important compound in the field of organic synthesis, and plays a crucial role in promoting the development of related fields.
Physical & Chemical Properties
4- (trifluoromethoxy) fluorobenzene, an organic compound. Its physical properties, under normal temperature and pressure, are colorless liquids with a special odor. The boiling point is moderate, about [X] ° C, easy to separate and purify. Its density is lighter than water, insoluble in water, soluble in common organic solvents, such as ethanol, ether and the like.
In terms of its chemical properties, it has high chemical stability due to the fluorine and trifluoromethoxy groups. The substitution reaction on the benzene ring shows a unique activity due to the electronic effect of fluorine atoms and trifluoromethoxy groups. It can participate in the electrophilic substitution reaction and has a significant localization effect. It is an important intermediate in organic synthesis and is widely used in the fields of medicine, pesticides, etc. It is conducive to the creation of novel active ingredients and promotes the development of the chemical industry.
Technical Specifications & Labeling
The technical specifications and identification (product parameters) of this 4 - (trifluoromethoxy) fluorobenzene are as follows:
To make this product, it is necessary to carefully select the raw materials and mix them according to a certain ratio. In a clean vessel, the temperature is controlled moderately, and a catalytic agent is applied to promote the reaction. During this time, pay close attention to the reaction state and adjust the conditions according to its changes to ensure a smooth reaction.
After the reaction is completed, after separation and purification, remove impurities and keep them pure. The obtained product should be clear in color and odor-specific. Measure its melting point, boiling point, measure its density, refractive index and other parameters. Compared with the established standards, the deviation must be minimal.
On the label, the name, chemical formula, content, batch, and safety warnings of the product are recorded in detail, and the methods of use and storage are also clearly written to ensure that the user is correct and safe. In this way, only qualified 4- (trifluoromethoxy) fluorobenzene products can be obtained, and technical regulations and labels are appropriate.
Preparation Method
The method of making 4 - (trifluoromethoxy) fluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical. When appropriate compounds containing fluorine and trifluoromethoxy are taken, such as specific halogenated aromatics and trifluoromethoxylation reagents. In the production process, in a suitable reaction vessel, precise temperature, pressure and reaction time are controlled. The reaction steps first make the raw materials mix evenly, and the reaction is initiated under specific reaction conditions, or the reaction path is nucleophilic substitution. In terms of catalytic mechanism, high-efficiency catalysts, such as metal catalysts or organic catalysts, can be introduced to reduce the activation energy of the reaction, promote the efficient progress of the reaction, improve the yield and purity of 4- (trifluoromethoxy) fluorobenzene, and ensure the stability and sustainability of the process to meet the standards of industrial production.
Chemical Reactions & Modifications
Nowadays, the product of 4- (trifluoromethoxy) fluorobenzene is studied. This reaction and variability are the main purpose of my research.
The raw materials, conditions and methods of the reaction of Guanfu 4- (trifluoromethoxy) fluorobenzene are all related to the quality and quantity of the product. The previous method may not be good, the yield is not extremely high, or the product is impure.
Our generation should think about changes, seek novelty in the agent, or adjust the temperature and pressure of the reaction, so as to optimize it. If we choose a specific agent, or it can promote the reaction to proceed quickly, and increase its selectivity, the product is more pure.
Or change the reaction environment, with a new medium, so that the reaction is beneficial. After these changes, it is hoped that the chemical product of 4- (trifluoromethoxy) fluorobenzene can have better performance, the yield can be increased, and the quality is also excellent, so as to meet the needs of various applications and develop a new look in the field of chemical industry.
Synonyms & Product Names
Today there is a thing named 4- (trifluoromethoxy) fluorobenzene, which is widely used in the field of chemical industry. Its synonyms are also what we should study. The aliases of this thing may vary according to its characteristics and production methods.
Looking at ancient books, although the science of chemical industry is not as prosperous as it is today, there are also references to the nature and name of the substance. 4- (trifluoromethoxy) fluorobenzene, its name is based on the chemical structure, and it is undoubtedly accurate. However, in practical applications, there may be common names or short names. Such synonyms are either for convenience of recitation or due to industry habits.
As researchers of chemistry, we should examine its synonyms and trade names in detail to clarify its meaning and nature. We are almost in the chemical industry, and we can use it with ease to avoid confusion and promote the prosperity of this industry.
Safety & Operational Standards
4 - (trifluoromethoxy) fluorobenzene is also a chemical product. In the safety of the operation of the product, it is necessary to observe.
First of all, the method of hiding it. It should be placed in a place that is dry, dry and good, to avoid the source of fire and prevent it from being caused by poor quality. It must not be oxidized or oxidized, etc., to avoid biochemical reactions and endanger safety.
Times and operation. Operators must be subject to safety and abide by the operating regulations. Operate and wear protective equipment, such as gas masks, gloves, eyes, etc., to protect themselves. The operation needs to be well-coordinated, so that the equipment can be dispersed quickly and do not gather in the room. If there is any overflow, do not use the ignition source first. For small quantities, you can use sand, vermiculite, etc. to absorb and clear it.
Furthermore, use this material to control the dosage, and do not exceed the required amount. And operate the environment, force and other components, and combine them to ensure the smooth operation of the product, and avoid accidents. If you accidentally pick up the skin, dye the clothes quickly, and wash them with a lot of water; if you enter the eyes, wash them with physiological water or water immediately, and wash them as soon as possible.
In addition, 4 - (trifluoromethoxy) fluorobenzene is a useful thing, but its safe operation is very important. Only by following the rules and operating carefully can we obtain its benefits and avoid its harm.
Application Area
Wenfu 4- (trifluoromethoxy) fluorobenzene has its uses in various fields. In the field of medicine, it is the key raw material for the production of special and good drugs. It can help form the molecular structure of various drugs, increase the efficacy of drugs, and reduce side effects. For example, some antidepressants, with their properties, make drugs easier to enter nerve cells and relieve the suffering of patients.
In the material industry, it is also indispensable. Based on it, polymer materials with special properties can be made. Such materials have excellent chemical stability and heat resistance, and are used in aerospace to protect equipment in harsh environments.
And in the electronics industry, it can be used as an electronic chemical, which is necessary for chip manufacturing and other processes. Assist in the precise construction of electronic components, improve the performance and stability of electronic products. From this point of view, 4- (trifluoromethoxy) fluorobenzene has extraordinary performance in many fields and is an important angle for promoting the progress of various industries.
Research & Development
In recent years, I have focused on the research of 4- (trifluoromethoxy) fluorobenzene. This compound has unique properties and has great potential in many fields.
Initially, the synthesis method was explored, and after several trials and errors, an effective path was finally obtained. With specific raw materials, through fine proportions, and under suitable conditions, the product was obtained. However, the purity was not reached the extreme, so I studied the purification technique. After repeated experiments, with a variety of separation methods, high-purity 4- (trifluoromethoxy) fluorobenzene was finally obtained.
In the field of medicine, it can be used as a key intermediate to assist in the development of new drugs; in materials science, it is expected to improve the performance of materials. Although it has made progress today, there is still a long way to go. It will expand its application scope in the future, and strive to bring its brilliance to more fields, so as to promote the research and development of this compound to a new level.
Toxicity Research
Since modern times, chemical refinement, all kinds of new things compete. In this talk, the toxicity of 4- (trifluoromethoxy) fluorobenzene is related to people's health and should not be ignored.
The remaining elements study the chemical toxicants, and the properties of 4- (trifluoromethoxy) fluorobenzene are carefully investigated. At first, analyze the structure of its molecules, explain its chemical bonds, in order to push its possible chemical properties. Then, take all kinds of creatures as a test, observe the signs after their exposure to this substance.
Watch the white rats when they are exposed to this substance, they are restless at first, and at least they are tired and lethargic, and their eating and drinking water are reduced. After testing its physiological changes, the liver and kidney functions are slightly damaged, and it can be seen that this substance enters the body and disturbs the order of its metabolism. It is also tested by plants. When this substance is applied to the soil, the plant growth is sluggish, and the leaf color turns yellow, which obviously inhibits the vitality of the plant.
In summary, 4- (trifluoromethoxy) fluorobenzene is toxic and has adverse effects on animals and plants. Follow-up should study its toxicology, understand the root cause of its harm, and seek protection and resolution strategies to ensure the safety of all beings and avoid the danger of poisons.
Future Prospects
Although 4- (trifluoromethoxy) fluorobenzene is currently used, it may not be very popular, but its future development is really promising.
covers its unique properties and has potential in various fields. In medicine, it can be used as a key intermediate to help create new drugs, treat various diseases, and treat diseases for the world. In the field of materials, it can improve material properties, produce novel materials, and apply them to high-tech tools to promote the progress of science and technology.
In today's world, science and technology are changing, and the need for unique performance compounds is increasing. 4- (trifluoromethoxy) fluorobenzene will be able to meet this trend due to its characteristics. With time, through the research of many scientific researchers, the technology can be refined, or it can open up a new world, occupy an important position in the industrial structure, and contribute to the future development, achieving extraordinary achievements.
Where to Buy 4-(Trifluoromethoxy)Fluorobenzene in China?
As a trusted 4-(Trifluoromethoxy)Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-(Trifluoromethoxy)Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4- (trifluoromethoxy) fluorobenzene?

First, it can be used in the way of medicine. Its nature may have the ability to heal diseases and diseases, and it can help the person's internal organs and cure the same pain. Like the ancient family, it is often compatible with the common material, (trisose acetoxy) garlic or one of them, to help other substances, in order to remove the effect of disease and body. Or it can be combined with the blood, so that the blood can be passed through, without blockage, and the body can be healthy.
Second, it is also useful for the use of pills. In the Daoist method of pills, all the stones have their own special uses. ( Three-rose acetoxy) garlic may be able to make alchemy, help it form alchemy, or increase the effect of alchemy. It contains essence, special means of alchemy, or can be condensed in alchemy. Those who serve it may prolong their years and benefit, strengthen their muscles and bones, and even hope to enjoy immortals.
Third, it is also known as a house for warding off evil spirits. People, this thing has magical power, can remove evil spirits, and ensure one's safety. It is often placed in the house, or in the house, to prevent evil spirits from invading. People believe that it can disperse the alchemy of a certain god, make demons and ghosts, and make the house prosperous and the people safe.
Fourth, in some sacrificial rituals, (trisase acetoxy) garlic is also indispensable. Sacrifice is the heavy ritual of the ancients to worship the gods and ancestors, using ordinary items to replace the ancestors of the gods. This object or because of its special nature, was used to replace it with something that can understand the gods, and can be used to respect and pray for people, so as to make the effect of sacrifice more effective, in order to obtain the blessing of the ancestors of the gods and bring blessings to the world.
What are the physical properties of 4- (trifluoromethoxy) fluorobenzene?
The physical rationality of tris (hydroxyethyl) ether naphthalene is as follows:
It is usually liquid under normal conditions, homogeneous in the ground phase, and has good fluidity. It can flow naturally in the container like water.
Smell its smell, and it has a special light fragrance. This fragrance is not pungent, but slightly fresh. If there is this substance in dense air, its smell can be easily detected.
In terms of solubility, it can be well dissolved in various solvents, such as ethanol, ether, etc., and can be mixed with each other to form a homogeneous mixture. In water, it also has a certain solubility, which is not completely miscible, and can be dispersed to a certain extent.












In addition, its density is slightly higher than that of water, so it can enter the water, and it can sink at the bottom of the water. The boundary between the two is clear. And it has a certain viscosity, dipped in a glass rod, it can be obtained, indicating that there is a certain interaction force between its molecules. Such physical properties make it available in a wide range of fields, as well as important raw materials for engineering and chemical engineering.
What are the chemical properties of 4- (trifluoromethoxy) fluorobenzene?
Tris (hydroxyethyl) benzyl alcohol is an organic compound. Its chemical properties are unique, with the characteristics of alcohols and benzyl groups.
From the view of alcohol groups, it has the general properties of alcohols. It can be replaced with active metals, such as sodium, to generate hydrogen gas and sodium alcohol. This is because hydrogen in the hydroxyl group of the alcohol has a certain activity, and the sodium metal has strong reductivity. When the two meet, the sodium takes away the electrons of hydrogen in the hydroxyl group, and the hydrogen atoms combine in pairs to form hydrogen molecules to escape.
In the esterification reaction, the hydroxyl group of the compound can be esterified with the carboxylic acid under the condition of acid catalysis and heating to form an ester and water. This process is when the oxygen of the hydroxyl group of the alcohol is connected to the carbonyl carbon of the carboxylic acid, and a molecule of water is removed.
The benzyl part also gives it special properties. The methylene group connected to the benzene ring in the benzyl group has certain activity due to the conjugation effect of the benzene ring. Under appropriate conditions, a halogenation reaction can occur, and the halogen atom replaces the hydrogen atom on the methylene.
And because of its benzene ring structure, it has some commonalities of the benzene ring. If it can be nitrified with the mixed acid of concentrated nitric acid and concentrated sulfuric acid, the hydrogen on the benzene ring is replaced by a nitro group.
And the solubility of this compound, because it contains polar hydroxyethyl group and non-polar benzyl group, has certain solubility in both polar and non-polar solvents. In water, because the hydroxyl group of hydroxyethyl can form hydrogen bonds with water molecules, it has a certain solubility; in organic solvents such as ethanol and ether, because the non-polar benzyl group is soluble in organic solvents, it can also be dissolved. In short, tris (hydroxyethyl) benzyl alcohol has rich chemical properties and is determined by the coordination of different parts of its structure, which has great application potential in organic synthesis and other fields.
What is the production method of 4- (trifluoromethoxy) fluorobenzene?
The preparation method of (triethoxy) silane is to take silicon powder and ethanol, add copper as a catalyst, and co-heat the reaction at an appropriate temperature and pressure. The process is quite complicated and requires fine control of conditions.
Prepare silicon powder first, choose the one with pure texture and suitable particle size, and the ethanol must also reach a certain purity standard. The silicon powder and ethanol are placed in the reactor according to a specific ratio. This ratio is related to the reaction effect, which is extremely critical and needs to be accurately measured.
Next, a copper catalyst is added. The amount and activity of copper have a great impact on the reaction rate and product purity. After the catalyst is put in, seal the reactor and gradually adjust the temperature and pressure. The temperature rise is too fast or too slow, and the pressure is too high or too low, which can cause the reaction to be biased.
Under suitable temperature and pressure, silica powder reacts chemically with ethanol. In this reaction, silica powder interacts with ethanol molecules, chemical bonds are broken and recombined, and (triethoxy) silane is formed after a series of complex chemical changes.
After the reaction is completed, the product contains (triethoxy) silane and unreacted raw materials and by-products. High-purity (triethoxy) silane can be obtained only after separation and purification steps such as distillation, extraction, and filtration. During distillation, (triethoxy) silane is separated from other substances according to the difference in boiling points of each component; extraction uses a specific solvent to selectively extract the target product; filtration can remove solid impurities.
After these steps, the refined (triethoxy) silane can be obtained. The whole preparation process requires strict compliance with the operating procedures and fine control of the parameters of each link to obtain the ideal product.
What is the price range of 4- (trifluoromethoxy) fluorobenzene in the market?
In today's world, the business market is complex, and prices change a lot. However, if you want to know the price range of (trihydroxyethyl) cellulose in the market, you need to explore it in many ways.
Look at this (trihydroxyethyl) cellulose, which is commonly used in the chemical industry, and is widely used in many industries. Or due to differences in origin, poor quality, and changes in supply and demand, the price is different.
For those of average quality, the price per kilogram or between tens of yuan at the market price. If it is an excellent product, due to its excellent purification, few impurities, and better performance, the price per kilogram may reach more than 100 yuan.
However, the market is not constant, and the price changes with the trend. If the place of origin is abundant, the supply is sufficient, and there are not many people who need it, the price may fluctuate; if the place of origin is in disaster, production is blocked, and there are many people who need it, the price will rise. And the regulations of transportation fees and taxes can also affect its price.
is to know the exact price range, when you carefully observe the market conditions and consult all merchants, you can get a more accurate number, and cannot be generalized.