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4-(Trifluoromethoxy)Chlorobenzene

4-(Trifluoromethoxy)Chlorobenzene

Hongda Chemical

Specifications

HS Code

251749

Chemical Formula C7H4ClF3O
Molar Mass 196.554 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 155 - 157 °C
Density 1.38 g/cm³
Solubility In Water Insoluble
Flash Point 49 °C
Refractive Index 1.446

As an accredited 4-(Trifluoromethoxy)Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottles for 4-(trifluoromethoxy)chlorobenzene, tightly sealed for storage.
Storage 4-(Trifluoromethoxy)chlorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container made of compatible materials, like steel or certain plastics. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions.
Shipping 4-(Trifluoromethoxy)chlorobenzene is shipped in accordance with strict chemical transportation regulations. It's typically in sealed, corrosion - resistant containers, safeguarded during transit to prevent leakage and ensure safety.
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4-(Trifluoromethoxy)Chlorobenzene 4-(Trifluoromethoxy)Chlorobenzene
General Information
Historical Development
4- (trifluoromethoxy) chlorobenzene is also a chemical product. At the beginning, the researchers explored its technology and tried it hard. At that time, the technology was not perfect, the material was not good, and it was difficult to get this product. However, the public worked tirelessly, and the research continued to change over the years. Gradually, the material selection was refined, the method was also improved, and the yield increased slightly. As a result, the quality and quantity of this product have improved. It is used in various fields of medicine and chemical industry, and it gradually develops its use and helps the industry. As the years go by, the researchers strive for refinement, hoping that it can have more outstanding effects in various industries. Pushing it to a new territory is also for the process of its development.
Product Overview
4- (trifluoromethoxy) chlorobenzene
4- (trifluoromethoxy) chlorobenzene is also an organic compound. Its shape is a colorless to slightly yellow liquid with a special odor. In the structure of this substance, on the benzene ring, there is one chlorine atom and one trifluoromethoxy group.
In the chemical industry, it has a wide range of uses. It can be used as a key intermediate in the synthesis of medicine and pesticides. In the research and development of medicine, or involved in the preparation of drugs for the treatment of specific diseases; in the creation of pesticides, or as the basis for the synthesis of high-efficiency insecticides and fungicides.
The synthesis method often uses specific benzene series compounds as the starting material, and is obtained through various reaction steps such as halogenation and etherification The control of reaction conditions is related to the purity and yield of the product.
However, this substance also needs to be properly disposed of. Because it has certain chemical activity, it must be handled according to specifications when storing and transporting to prevent its leakage, which may cause environmental hazards and personal risks.
Physical & Chemical Properties
4- (trifluoromethoxy) chlorobenzene is also an organic compound. Its physical and chemical properties are related to the properties and applications of this substance.
Looking at its physical properties, it is mostly liquid at room temperature, with a specific color and odor. Its boiling point and melting point are key parameters for the phase transition of substances, which can help to observe its stability. And its density is related to the distribution in the medium.
On its chemical properties, it shows unique reactivity because it contains chlorine and trifluoromethoxy groups. Chlorine atoms are active and can involve reactions such as nucleophilic substitution; trifluoromethoxy groups have strong electron absorption, which affects the distribution of molecular electron clouds, making this compound show a special tendency in chemical reactions. The study of these properties is of great significance in the fields of organic synthesis and materials science, and can lay the foundation for related applications.
Technical Specifications & Labeling
There is a chemical product today, named 4- (trifluoromethoxy) chlorobenzene, which is related to technical regulations and identification (product parameters), which is very important.
Preparation of this product requires precise methods. Take an appropriate amount of raw materials first, and the proportion must be appropriate. In a clean vessel, control it at a moderate temperature, accompanied by an appropriate agent, to phase all substances. In the meantime, observe its changes, abide by its laws, and do not make a slight difference.
After the reaction is completed, the product needs to be refined. In a specific way, remove its impurities and improve its purity.
As for the logo, when the product parameters are stated. Such as purity geometry, impurity geometry, and properties, all need to be detailed. This is not only the certificate of quality, but also the user knows its nature and makes good use of it. Only by strictly abiding by the technical regulations and labels can you get good things for all kinds of uses.
Preparation Method
To prepare 4 - (trifluoromethoxy) chlorobenzene, the raw materials, production process, reaction steps, and catalytic mechanism are the key. First, an appropriate amount of chlorobenzene is taken as the starting material, mixed with a specific trifluoromethoxy reagent in an organic solvent. Adding a suitable catalyst, this catalyst can effectively reduce the activation energy of the reaction and promote the reaction between the two. Warm to a suitable temperature to maintain a stable reaction state of the reaction system. After several hours, the reactants are fully reacted. Subsequent separation methods such as distillation and extraction are used to purify the product. Among them, precise screening and dosage control of the catalyst are crucial, which are related to the reaction rate and product purity. The reaction temperature and time also need to be strictly controlled to ensure that the preparation process is efficient and stable to obtain high-purity 4- (trifluoromethoxy) chlorobenzene products.
Chemical Reactions & Modifications
There is now a chemical substance named 4- (trifluoromethoxy) chlorobenzene. To investigate its chemical reaction and modification, this is the focus of our research.
Its reactants may interact with nucleophiles. On the cover benzene ring, the position of the chlorine atom and the trifluoromethoxy group can cause the nucleophile to approach and undergo a substitution change. Nucleophiles use their electron-rich properties to attack the carbon connected to the chlorine atom, and the chlorine leaves to form a new bond. This is a common reaction route.
As for modification, different functional groups can be added to the benzene ring. By chemical methods, such as amino groups, hydroxyl groups, etc., or by coupling reactions, long-chain hydrocarbon groups can be connected. In this way, its physical and chemical properties are changed. It can increase its solubility or change its reactivity, opening up new ways for various applications. Hope this research will gain in various fields of chemistry, such as materials and medicine.
Synonyms & Product Names
Today there is a thing called 4- (trifluoromethoxy) chlorobenzene. This thing is used in the field of chemistry and has a wide range of uses. Its aliases and trade names also need to be investigated in detail.
Many chemical substances have the same name and aliases. This 4- (trifluoromethoxy) chlorobenzene may have another name. Or because of its characteristics, or because of the production method, it has different names in different places and at different times. And the name of the trade name is also named by the merchant in recognition of the excellence of its product.
For us chemical researchers, it is crucial to distinguish its aliases and trade names. The synonym can help us to widely refer to the classics and gain insight into the past research of this thing; the trade name allows us to know its circulation in the market and the field of its application. Therefore, exploring the synonym and trade name of 4 - (trifluoromethoxy) chlorobenzene is an indispensable task for the study of this chemical.
Safety & Operational Standards
Specifications for the safety and operation of 4- (trifluoromethoxy) chlorobenzene
Fu 4- (trifluoromethoxy) chlorobenzene is also an important product for chemical research. Its unique nature is related to the safety of experiments and the regulations of operation, which must not be ignored.
In the storage section, it is necessary to choose a cool, dry and well-ventilated place. Cover its nature or fear heat, bad moisture, loss of temperature and humidity, fear of qualitative change, and even life insurance. The reservoir must also be carefully selected, and it must be sealed without leakage to prevent it from escaping from the outside, staining and surrounding.
As for the operation, all kinds of protection are indispensable. The operator wears appropriate protective clothing, so as to prevent it from connecting with the body and skin; wears special goggles to protect the eyes from damage; and wears protective gloves to prevent it from touching the hands. And the operation should be carried out in the fume hood, so that the foul gas can dissipate quickly, so as not to accumulate in the room and harm the person.
If there is no leakage, the first thing to do is to quickly leave unrelated people and make a safe place. Operators need to wear professional chemical protection equipment, and carefully clean up leaks. Do not let leaked products enter ditches and waterways, so as to avoid pollution and water sources, which will cause disasters to the environment.
Furthermore, when taking the amount, it should be accurate, not to be greedy and waste, and to avoid less than expected. After use, place it in its original place, and adjust the equipment for later use.
In short, the safety and operation of 4- (trifluoromethoxy) chlorobenzene involve human life and the success or failure of the experiment. Only by following the rules and being rigorous can we ensure safety and promote the smooth progress of research.
Application Area
4- (trifluoromethoxy) chlorobenzene is widely used in the field of chemical industry. In the process of pharmaceutical synthesis, it is often a key intermediate. Due to its unique structure, it can introduce special groups to make the drug have better pharmacological activity.
In the field of pesticide creation, it also has extraordinary performance. With its chemical properties, it can help synthesize high-efficiency and low-toxicity pesticides, protect agricultural mulberry, and resist pests.
In the context of material science, it can participate in the preparation of special materials. Help materials obtain special properties, such as weather resistance, corrosion resistance, etc., to meet diverse needs.
This compound, in various application fields, has shown important functions, contributing to chemical research and industrial development, and promoting progress.
Research & Development
I have dedicated myself to the research of chemical products. Recently, I have done a lot of research on 4- (trifluoromethoxy) chlorobenzene. This material is unique in nature and has a wide range of uses. It is useful in various chemical fields.
I began to study its synthesis method, read the classics, find the methods left by the predecessors, and also participate in the new technologies of today. After repeated experiments, I have improved the old method, hoping for a better method. When synthesizing, the selection of raw materials and the control of conditions need to be fine. If the temperature and pressure are slightly different, the product may vary.
As for the development of applications, no effort will be spared. Explore its possibilities in the pharmaceutical and pesticide industries. In medicine, it can be used as a key intermediate to assist in the research of new drugs; in pesticides, it can be a synergistic agent to protect agricultural production.
Although there are many difficulties in the way forward, I hold the heart of research and hope to make breakthroughs in the research and development of 4- (trifluoromethoxy) chlorobenzene, which will contribute to the chemical industry and promote its long-term development.
Toxicity Research
I will study the toxicity of 4- (Trifluoromethoxy) Chlorobenzene. This compound has attracted much attention in the field of chemical industry, but the details of its toxicity still need to be explored in depth.
View of previous research, or its impact on the environment. If this substance is released outside, it may be an ecological hazard. It enters the water body, or harms the aquatic genus, causing its physiological violation and hindering its reproduction.
As for the human body, although it has not been widely confirmed, it is deduced from the same kind of reason, or it is harmful to health through breathing and contact. Or damage the respiratory system, or invade the nervous system.
If you want to know the truth of its toxicity, you should use scientific methods and strict regulations to conduct various experiments. To observe its response to living beings and analyze its metabolic path, in this way, you can obtain the truth of its toxicity, think that it is the basis for prevention, so that the chemical industry can benefit and avoid its harm.
Future Prospects
Our generation's research on chemical products is based on 4- (trifluoromethoxy) chlorobenzene, with a vision for the future. This material is unique and has a wide range of uses. Looking at today's chemical industry, the demand for fine chemicals is increasing day by day. 4- (trifluoromethoxy) chlorobenzene may be used in the synthesis of medicine as a key raw material to help the development of new drugs and solve the suffering of patients. In the field of materials science, it may also emerge as the basis for new materials, making materials have specific properties, such as better weather resistance and corrosion resistance. We should do our best to study and refine, hoping to expand its application, improve the preparation method, reduce its cost and improve its quality. With time, this material may be used to promote the progress of the chemical industry, bring more benefits to the world, and open up a new future for the chemical industry.
Where to Buy 4-(Trifluoromethoxy)Chlorobenzene in China?
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Frequently Asked Questions

As a leading 4-(Trifluoromethoxy)Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4- (trifluoromethoxy) chlorobenzene?
(Trihydroxyethyl) hydrazine-boron is a rare substance today, and it is widely used. This substance has great functions in chemical synthesis.
In the field of organic synthesis, (trihydroxyethyl) hydrazine-boron is often used as a reducing agent. Aldides and ketones can be converted into alcohols. Such as aldehyde compounds, when encountering (trihydroxyethyl) hydrazine-boron, the aldehyde group is reduced to a hydroxyl group and converted into a corresponding alcohol. This process is mild and has good selectivity. It does not disturb other functional groups of the molecule. In the synthesis of complex organic molecules, it maintains its structural integrity and accurately obtains the target product.
In the context of materials science, it is also useful. Can participate in the preparation of special materials, such as some functional polymer materials. ( The properties of trihydroxyethyl) hydrazine and boron can improve the properties of materials, making them have better stability, mechanical properties or electrical properties. For example, when preparing conductive polymer materials, adding them can help intermolecular charge transfer and increase the conductivity of materials.
In the path of pharmaceutical chemistry, (trihydroxethyl) hydrazine and boron also help. In the synthesis of drugs, it can be used for the synthesis of key intermediates. Due to its controllable reduction properties, it can obtain compounds of specific configurations, providing various possibilities for the development of new drugs, and helping to find high-efficiency and low-toxicity medicines.
In analytical chemistry, it can also be seen. Can be used as a reagent for the detection and analysis of specific substances. By means of its specific reaction with certain compounds, the type and content of substances can be measured according to the reaction phenomenon or product characteristics, providing an effective means for analytical work.
In short, (trihydroxyethyl) hydrazine and boron have many uses and have contributed to various fields, helping scientific progress and technological development.
What are the physical properties of 4- (trifluoromethoxy) chlorobenzene?
Triethoxysilane has a water-like shape, is clear and transparent, and has a specific smell. Its boiling point is quite low, between 134 and 136 degrees Celsius. It is more volatile at room temperature and pressure, which is one of its major physical characteristics.
Looking at its density, it is about 0.905 to 0.908 grams per cubic centimeter, which is lighter than water, so if it is mixed with water, it will float on water. Its solubility is also characteristic, and it can be soluble in common organic solvents, such as ethanol, ether, etc. However, it is only slightly soluble in water.
Furthermore, the flash point of triethoxysilane is not high, about 28 degrees Celsius, which means that it is flammable, easy to burn in case of open flames and hot topics. When storing and using, you need to pay great attention to fire safety and do not slack a little. Its steam and air can form an explosive mixture, and if it encounters a fire source, it is at risk of explosion, which is a dangerous thing.
In addition, the refractive index of this object is also fixed, about 1.377 to 1.380. This optical property may have its unique use and value in specific optical materials, analysis and testing, etc. Therefore, the physical properties of triethoxysilane are diverse, and in many aspects such as industrial production and scientific research, it is not only useful because of its characteristics, but also because of its flammable, explosive and other dangerous characteristics, it needs to be properly disposed of and treated with caution.
What are the chemical properties of 4- (trifluoromethoxy) chlorobenzene?
Tris (triethoxy) silane has unique chemical properties. This substance contains silica bonds and ethoxy groups, making it hydrolytic. When exposed to water, ethoxy groups will react with water molecules and gradually hydrolyze to form silanol groups (Si-OH), and ethanol will escape. This hydrolysis process is significantly affected by environmental humidity, temperature and pH. In a moderately alkaline environment, the hydrolysis rate may be accelerated.
Because of its hydrolytic properties, tris (triethoxy) silane is often used as a coupling agent. It can form covalent bonds by condensing the hydrolyzed silanol groups with the hydroxyl groups on the surface of inorganic substances; at the same time, the hydrolyzed residues of ethoxy groups can interact with organic substances, thus enhancing the interfacial binding effect between inorganic and organic substances.
In addition, the substance also has good chemical stability. Under normal conditions, it is inert to most chemical reagents. However, when exposed to strong oxidizing agents or strong acids, it may react, causing changes in its structure and properties. Its thermal stability is also worthy of attention. It can maintain structural stability within a certain temperature range; but if the temperature is too high, it may cause decomposition or other chemical reactions. Because of its unique properties such as hydrolysis and chemical stability, it has important uses in many fields such as material surface modification and composite preparation, and plays a key role in enhancing interface bonding and improving material properties.
What is the preparation method of 4- (trifluoromethoxy) chlorobenzene?
The method of making triethoxysilane is to use silicon powder and ethanol, accompanied by a copper-based catalyst, to react at a specific temperature and pressure.
Prepare silicon powder first, choose the one with high purity and suitable particle size. The purity of the silica powder is related to the purity of the product, and the particle size is related to the reaction rate. To recover ethanol, it also needs to meet the corresponding purity standards. Put the silicon powder and ethanol in a suitable ratio in a special reactor. This reactor needs to be temperature-resistant and pressure-resistant, and has good stirring and heat transfer properties to ensure that the reaction is uniform and efficient.
Then, a copper-based catalyst is added. This catalyst is crucial in the reaction, which can greatly reduce the activation energy of the reaction and promote the rapid occurrence of the reaction. The dosage needs to be precisely controlled. Too much or side reactions will increase, and too little will slow down the reaction rate.
Set the reaction temperature and pressure. The temperature is usually controlled within a certain range. If it is too low, the reaction rate will be slow. If it is too high or side reactions will intensify, the purity of the product will decrease. The same is true for pressure, which must be adapted to the temperature to create an environment conducive to the reaction.
During the reaction, the material is fully mixed by means of a stirring device. At the same time, the reaction process is closely monitored, and the temperature, pressure and other parameters are observed to change, and fine-tuned in a timely manner according to the actual situation.
After the reaction is completed, the product goes through distillation, purification and other processes. Distillation can separate the crude triethoxysilane according to the difference in After purification, impurities are removed to obtain high-purity triethoxysilane.
This preparation method has been continuously optimized and has been quite mature. It can stably produce high-quality triethoxysilane and is widely used in many fields of chemical industry.
What are the precautions for using 4- (trifluoromethoxy) chlorobenzene?

The first one is poisonous, and it can be harmful if it is touched, smelled or entered into the body. When using it, you must wear suitable protective equipment, such as gloves, masks, and eyepieces, to avoid contact with the skin, eyes, and breathing. If you accidentally touch it, rinse it with a lot of water quickly, and you still feel unwell, and seek medical attention.
The second time, its flammability is important. Keep it away from open flames and hot topics, and place it in a cool and ventilated place, and there should be no flammable or explosive objects around. After use, be careful to put out the utensils to prevent fire.
Furthermore, in the storage area, it should be sealed in a sealed container to avoid moisture absorption and deterioration. Temperature and humidity should also be controlled, and over-temperature and humidity can affect its quality. Also remember that the storage area should be clearly marked, so that it can be recognized and managed.
Again, the process of use should be subject to strict regulations and laws. The operator must be specially trained in advance to understand its nature and use, and should not change the process without authorization. The amount used should also be controlled in a standard manner, so as not to cause risk of waste and overuse.
Also, do not discard the finished utensils and residue. Dispose of it according to regulations, anti-fouling ring. Waste utensils and residual liquid should be placed in the designated device, and handled by a special company.
In short, when using trihydroxyethylaminane, you must be very careful and pay attention to all the ends in order to be safe and smooth.