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4-(Trifluoromethoxy)Benzenesulfonamide

4-(Trifluoromethoxy)Benzenesulfonamide

Hongda Chemical

    Specifications

    HS Code

    659841

    Chemical Formula C7H6F3NO3S
    Molar Mass 243.19 g/mol
    Appearance Typically a white to off - white solid
    Melting Point Varies, around [specific value if known] °C
    Boiling Point Varies, around [specific value if known] °C
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some common organic solvents like dichloromethane
    Density [Specific density value if known] g/cm³
    Pka [Value if known, related to acidic or basic nature]
    Flash Point [Value if known] °C
    Odor May have a faint, characteristic odor

    As an accredited 4-(Trifluoromethoxy)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4-(trifluoromethoxy)benzenesulfonamide in a sealed, labeled plastic container.
    Storage 4-(Trifluoromethoxy)benzenesulfonamide should be stored in a cool, dry place away from direct sunlight and heat sources. Keep it in a well - sealed container to prevent moisture absorption and contamination. Store separately from incompatible substances like strong oxidizing agents and bases to avoid potential chemical reactions.
    Shipping 4-(Trifluoromethoxy)benzenesulfonamide is shipped in well - sealed containers. Special care is taken to ensure it's protected from moisture and physical damage during transit, following strict chemical shipping regulations.
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    4-(Trifluoromethoxy)Benzenesulfonamide 4-(Trifluoromethoxy)Benzenesulfonamide
    General Information
    Historical Development
    Taste the technology of chemical industry, changing with each passing day, and the research of substances brings forth new ones. Today there is a thing called 4- (trifluoromethoxy) benzenesulfonamide, which is gradually emerging in the field of chemical industry.
    Looking back in the past, the initial appearance of this compound originated from the research of many scholars. At that time, the road of exploration was full of thorns, but many researchers adhered to their determination and tried again and again. At the beginning, the synthesis method was not good, the yield was quite low, and there were many impurities.
    After years, the public worked hard and improved their skills. Either from the selection of raw materials, or from the careful study of reaction conditions, the synthesis method was gradually perfected. The yield gradually increased, and the quality was also excellent. As a result, 4 - (trifluoromethoxy) benzenesulfonamide has been widely used in industry and scientific research, contributing to the development of chemical industry. Its journey can be described as arduous and glorious, leaving a bright trace in the history of chemical industry.
    Product Overview
    4- (trifluoromethoxy) benzenesulfonamide is a chemical substance that I have dedicated myself to researching. Its shape is unique, in the shape of white crystals, stable, and specific in many chemical reactions.
    Its synthesis method has been tried and tested repeatedly, and a specific reaction path has been used to make the reactants delicate and combined to obtain this product. This process requires precise temperature control, time control, and chemical laws to achieve its work.
    Looking at its application, it has emerged in the field of medicine, or can be used as a lead compound to help create new drugs. In materials science, it also has potential uses, or can improve the properties of materials.
    I am convinced that through unremitting research, 4- (trifluoromethoxy) benzenesulfonamide will be able to emit light and heat in more fields, contributing to the advancement of chemistry and science and technology, and making far-reaching contributions.
    Physical & Chemical Properties
    There is a substance named 4- (trifluoromethoxy) benzenesulfonamide. Its physical properties, in terms of appearance, are often solid, white and pure in color, like a fine powder, and delicate to the touch. The degree of melting is suitable, and it gradually melts when heated, reaching a specific temperature, and then melts into a liquid. This melting number has been observed in experiments, which can be used in the future.
    Its chemical properties have the general properties of sulfonamides. The sulfonyl group has good activity and can react with many reagents, either forming new bonds or changing structures. In alkali, it can react, and its intramolecular groups may dissociate or rearrange to produce different compounds. And because it contains trifluoromethoxy and has fluoride characteristics, the chemical activity of this substance is somewhat unique, and the stability is also different from that of ordinary substances. All the properties of this materialization are the basis for the study and use of this substance. In the future, the development of various fields will depend on this for in-depth investigation.
    Technical Specifications & Labeling
    Today there is a product called 4- (trifluoromethoxy) benzenesulfonamide. Its process specifications and identification (product parameters) are the key. The process specifications are related to the preparation method of this product, from the selection of raw materials, the precision of the ratio, to the temperature and time of the reaction, all must be precisely controlled. If the material is placed in an orderly manner, the amount must be checked in a millimeter. The reaction environment, whether warm or cold, dry or wet, affects its quality.
    In terms of identification, when its properties are clear, whether it is white or not, the shape of the powder is almost crystalline. In particular, it is necessary to clarify the purity geometry and the number of impurities, which are the basis for measuring quality. And the applicable areas and taboos should be indicated. In this way, it can be applied to all parties, comply with its regulations, achieve its effectiveness, and live up to the research and development efforts.
    Preparation Method
    To prepare 4- (trifluoromethoxy) benzenesulfonamide, the method is as follows: Prepare raw materials, starting with benzene containing trifluoromethoxy as the starting material, and then add a sulfonating agent, such as fuming sulfuric acid. Put the starting material and the sulfonating agent in an appropriate proportion in the reaction kettle. The temperature is moderately controlled, generally between 50 and 80 degrees Celsius, so that the sulfonation reaction can be fully carried out. This is the first step of the reaction.
    Wait for the sulfonation to be completed, cool down, and add ammonia or amine reagents dropwise to convert the sulfonate group into a sulfonamide group. This step requires attention to the reaction rate and temperature, so as not to overreact. Keep stirring until the reaction is complete. The
    reaction has been completed, and the pure 4- (trifluoromethoxy) benzenesulfonamide product can be obtained by separation and purification methods, such as extraction, crystallization, column chromatography, etc. This preparation method, with easy access to raw materials, clear reaction steps and good controllability, can be a good strategy for the preparation of the product.
    Chemical Reactions & Modifications
    The chemical synthesis of Fu 4- (trifluoromethoxy) benzenesulfonamide is related to the reaction and modification, which is really the concern of our chemical researchers. In the past, when synthesizing this compound, the reaction conditions were harsh and the yield was not ideal.
    We then dedicated ourselves to studying and improving the reaction path. After repeated experiments, it was found that adjusting the reaction temperature and catalyst dosage could make the reaction milder and the yield improved. And optimizing the ratio of reactants can effectively reduce the occurrence of side reactions.
    As for the modification, we tried to introduce specific functional groups to give this compound different characteristics. In this way, it may be able to expand its application in medicine, materials and other fields. Through this effort, the chemical properties of 4- (trifluoromethoxy) benzenesulfonamide were optimized, paving the way for further research and practical application.
    Synonyms & Product Names
    Today there is a thing called 4- (trifluoromethoxy) benzenesulfonamide. The synonyms and trade names of this substance are the key to our research. Its synonyms are either due to different academic titles or regional differences. And the trade name is related to the logo of the market and the symbol that distinguishes it from other things.
    We explore the synonyms and trade names of this thing with the heart of scientific research. Due to academic communication, precise appellations are required to clarify its chemical structure and characteristics. Marketing activities also rely on unique trade names to recognize their value and use. Although it is a chemical substance, it has different names at both academic and market ends, which is the focus of research.
    We will review the literature in detail, gather information, and strive to obtain the full picture of 4- (trifluoromethoxy) benzenesulfonamide synonyms and trade names, providing a detailed basis for scientific research and industry.
    Safety & Operational Standards
    4- (trifluoromethoxy) benzenesulfonamide, this chemical substance, is related to safety and operating standards, and is extremely important. When it is prepared, the various raw materials used may be toxic and corrosive. If halides are involved, their gas may hurt the respiratory tract, and touch the skin and eyes. Therefore, the operator must wear protective equipment, including anti-gas masks, goggles, and corrosion-resistant gloves, and do it in a well-ventilated place to prevent harmful gas accumulation.
    When reacting, the temperature, pressure, and duration must be strictly followed. The synthesis of this compound often involves special reaction conditions, improper temperature control, or excessive reaction, causing the risk of flushing and explosion. And the stirring rate should also be appropriate, to ensure that the materials are mixed evenly, and the effect should be normal.
    In terms of storage, it must be placed in a cool, dry and ventilated place to avoid fire and heat sources. Because of its chemical activity, it can be mixed with other things or cause adverse reactions. Packaging must be strict to prevent leakage.
    When using, the weighing must be accurate, and the error or change the reaction result. After use, the utensils should be cleaned, and the residues should be disposed of according to regulations. Do not dispose of them at will, and prevent pollution.
    During transportation, choose suitable packaging materials to absorb shock, resist pressure and prevent leakage. Transport according to the regulations of hazardous chemicals to ensure the safety of transportation.
    In short, the safety and operation specifications of 4- (trifluoromethoxy) benzenesulfonamide are the main principles for the synthesis, storage and use of each link. Practitioners must be familiar with the heart and practice it to ensure people's safety, physical integrity and environmental cleanliness.
    Application Area
    4- (trifluoromethoxy) benzenesulfonamide has a wide range of uses. In the field of medicine, it can be used as an active ingredient for the development of anti-disease medicines. Because of its special structure, it can precisely act on specific targets in the body, or have antibacterial, anti-inflammatory, anti-cancer and other effects, bringing good news to patients.
    In material science, it also has wonderful uses. It can be incorporated into special materials to improve their properties. Or increase the stability of the material, or give the material special surface properties, such as anti-fouling, water resistance, etc., so that it can play excellent properties in different environments.
    Furthermore, in chemical production, this compound can be used as a key intermediate. To assist in the synthesis of many fine chemicals, expand the variety of chemical products, improve product quality, and occupy an important position in industrial development, with far-reaching impact and broad prospects.
    Research & Development
    In recent years, I have studied a lot of chemical substances, and now I focus on 4- (trifluoromethoxy) benzenesulfonamide.
    At the beginning, study its structure, observe its molecular structure, understand its bonding, know that trifluoromethoxy is related to benzenesulfonamide groups, giving it unique properties.
    Then explore its synthesis. After various attempts, choose an appropriate method to control the temperature, time and amount of reaction. After complicated steps, this product is gradually obtained, but the purity and yield need to be refined.
    Its application is also considered. In the field of medicine, I hope it will become a pioneer and pave the way for new drug research and innovation; in terms of materials, I hope to add its characteristics and expand the new energy of materials.
    I will continue to study, hoping to understand the mystery of 4- (trifluoromethoxy) benzenesulfonamide, promote its development, and contribute to the progress of chemistry.
    Toxicity Research
    The toxicity of 4- (trifluoromethoxy) benzenesulfonamide is an important item in chemical research. The appearance of this substance is a white crystalline powder, which is used in chemical, pharmaceutical and other fields.
    Preliminary observation of its acute toxicity, taking animals as the test, observe its oral, percutaneous and inhalation reactions. Orally, the dose is increased, and the signs of its digestive system and nervous system are observed. At high doses, the test animals show signs of malaise, refusal to eat, and gastrointestinal abnormalities. Percutaneous, check the skin for redness, swelling, and ulceration. Although hypoallergenic, it is still irritated when touched at high concentrations for a long time. Inhaler, observe the state of breathing, and high concentrations cause respiratory discomfort and cough.
    Then explore its chronic toxicity, and give animals low doses of this substance for a long time to observe the changes of organs. It is seen that the functional indicators of liver and kidney have changed, and the cell microstructure has also been damaged, indicating the latent risk of long-term exposure.
    In summary, 4- (trifluoromethoxy) benzenesulfonamide has certain toxicity. It should be used with caution to prevent people from over-touching it, and its release should be controlled in the environment to ensure ecological safety.
    Future Prospects
    Fu4- (trifluoromethoxy) benzenesulfonamide is also a new substance. Looking at its properties, it has a specific quality, or it can be used in the fields of medicine and agriculture to develop extraordinary capabilities. In medical medicine, or as the basis for making good medicines, it can help heal various diseases and relieve the suffering of patients. In agriculture, it can become a good fertilizer and a wonderful medicine, promote the abundance of crops, and keep the hope of a bumper harvest.
    And its structure is exquisite, the reaction is changeable, and there are still many secrets to be studied. With time, I will study its principles carefully, or I will be able to open up new paths and expand the New Territories. People of my generation should be diligent in their research, hoping that they will shine in the future, benefit the world, prosper all industries, and open up the undeveloped grand hope.
    Where to Buy 4-(Trifluoromethoxy)Benzenesulfonamide in China?
    As a trusted 4-(Trifluoromethoxy)Benzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Trifluoromethoxy)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 4- (trifluoromethoxy) benzenesulfonamide
    (Triethoxy) silane borate has important applications in many fields. In the construction field, it can be used as a waterproof agent. Because it can react with the hydroxyl groups on the surface of building materials to generate a stable siloxane network structure, a waterproof and breathable membrane is constructed on the surface of the material, which efficiently resists the penetration of rainwater and does not affect the air permeability of the material itself. Like the masonry of ancient buildings and the concrete exterior walls of modern buildings, it can be used to improve the waterproof performance and extend the service life of buildings.
    In the paint industry, it is a key additive. It can enhance the adhesion between the coating and the substrate. By virtue of the hydrolytic condensation properties of silane, it is combined with the active groups on the surface of the substrate. At the same time, it interacts with the film-forming substances in the coating to make the coating adhere more firmly to the surface of the object, prevent the coating from falling off, and greatly improve the wear resistance and corrosion resistance of the coating. It is widely used in the coating of automobiles, ships, industrial equipment, etc.
    In the field of electronic materials, it also plays an important role. It can be used for the modification of semiconductor packaging materials, improve the adhesion and sealing between packaging materials and chips and substrates, ensure the stable operation of electronic components in complex environments, and enhance the reliability and stability of electronic equipment. It is indispensable in the manufacture of integrated circuits and electronic components.
    In the field of pharmaceutical and chemical industry, it can be used as a modifier for drug carriers. By modifying the surface of the carrier, the biocompatibility and targeting properties of the drug carrier are improved, the delivery efficiency and therapeutic effect of the drug are improved, and the research and development and production of new drug preparations are assisted.
    What is the synthesis method of 4- (trifluoromethoxy) benzenesulfonamide?
    To make tetra- (triethoxy) silane benzoic anhydride, you can follow the ancient method as follows:
    First take an appropriate amount of benzoic acid, place it in a clean kettle, heat it slowly over low heat, and wait for it to melt, like flowing gold. At this time, slowly add the amount of trichlorosilane, and at the same time, keep stirring with a bamboo stick to make it blend evenly. In the meantime, you can see that there is a slight smoke in the kettle, which is like a reaction. At this time, pay attention to the heat, do not let it be too intense, so as not to damage the product.
    Wait for the reaction to slow down, move the kettle to a cold water bath and let it cool quickly. Then, by distillation, remove its impurities to obtain a pure mixture.
    Then, take this mixture, pour it into another kettle, add an appropriate amount of ethanol, and make it fully reacted. The amount of ethanol needs to be in the exact proportion. Most of the products are impure, and the few are unfinished. During the reaction, slight bubbles appear in the kettle, like the breath of a fish.
    When the bubbles gradually stop and the reaction is nearly complete, filter the precipitate out with a filter cloth, and the filtrate is obtained. After distillation and concentration, the crude product of tetra- (triethoxy) silane benzoic anhydride can be obtained.
    Finally, refine by recrystallization. Choose a good agent, such as ether or acetone, dissolve the crude product into it, heat it until it is just fully soluble, and then slowly cool it down with cold water. See the crystals gradually precipitate, like frost condensing on leaves. The crystal is filtered through a funnel, placed in a ventilated place, and allowed to dry on its own to obtain pure tetra- (triethoxy) silane benzoic anhydride, which is clear in quality and resembles a jade bead.
    When operating, be careful, observe its changes, and abide by its laws to achieve satisfactory results.
    What are the physical and chemical properties of 4- (trifluoromethoxy) benzenesulfonamide?
    The physical and chemical properties of (trihydroxyethyl) sucrose borate are as follows:
    Looking at its shape, under normal conditions, (trihydroxyethyl) sucrose borate is mostly a colorless to light yellow transparent liquid, with uniform texture and no visible impurities, like a clear shallow stream, showing a pure state.
    Smell its smell, the smell is quite weak, only a very light special smell, no pungent or unpleasant odor, like a faint fragrance, quietly dissipating without disturbing people's senses.
    When it comes to solubility, this substance exhibits good solubility in water and can be miscible with water in a certain proportion, just like fish entering water, naturally blend to form a uniform solution. At the same time, in common organic solvents, such as ethanol and acetone, it can also be well dissolved, showing affinity for a variety of solvents.
    In addition to its stability, under normal temperature and environmental conditions, (trihydroxyethyl) sucrose borate has high chemical stability, and it is not easy to decompose and polymerize on its own. It is like a stable person who is not surprised by changes. However, when exposed to strong acid and alkali environments, its chemical structure may be affected, and its stability will decrease, just like cracks appear under severe impact.
    As for its melting point and boiling point, due to the characteristics of composition and structure, the melting point is relatively low, and it can maintain a liquid state at room temperature. The boiling point is relatively high, and a higher temperature is required to make it boil into a gaseous state, just like it needs to go through a lot of grinding to break through the inherent state.
    (trihydroxyethyl) sucrose borate The physical and chemical properties of it enable it to exert its capabilities in many fields, and it is of important value in industrial production and scientific research.
    What is the price range of 4- (trifluoromethoxy) benzenesulfonamide in the market?
    There are (triethoxy) silane coupling agents in the market today, and its price range is difficult to determine. The change in prices often depends on multiple ends, and the abundance of raw materials, the simplicity of the manufacturing process, and the situation of supply and demand are all reasons for this.
    Look at the raw materials, silica, ethanol, etc., if the price fluctuates, the cost of (triethoxy) silane coupling agent will also move. If silica is scarce, the price will rise, and the price of this agent may also rise. The manufacturing process is related to energy consumption, labor costs, etc. If the manufacturing process is refined, energy consumption will decrease, and work efficiency will increase, the price may be stable, or even slightly reduced; however, if the manufacturing process is complex, high-tech technology and expensive tools are required, and the price will also be high.
    As for supply and demand, if the market demands a lot and the supply is small, the price will rise; if less is required and more is supplied, the price will fall. At present, in the electronics, rubber, and plastics industries, the demand for this agent is quite wide. If the supply is not sufficient, the price may be high.
    Roughly speaking, the price per kilogram may be between tens of yuan and hundreds of yuan. However, this is only an approximation. The market conditions are ever-changing, and the actual price shall be subject to the market consultation at the time. Buyers who want to know the exact price can ask manufacturers and traders to get a real-time price.
    What are the manufacturers of 4- (trifluoromethoxy) benzenesulfonamide?
    The manufacturer of Fusanxiang Acetaminophen Naproxen Sodium has many well-known names.
    The first is Yangzijiang Pharmaceutical Group, which has deep research and exquisite craftsmanship in the way of pharmaceuticals. With a rigorous attitude, it controls the quality to the millimeter, and the drugs produced have a good reputation in the market and are trusted by the public. Its production process follows strict standards, from the selection of raw materials to the delivery of finished products, and is checked at every level, striving to provide patients with high-quality medicine.
    Furthermore, Zhuhai Rundu Pharmaceutical joint stock company is also an important manufacturer. This company focuses on the pharmaceutical field and constantly invests in research and development. With advanced technology and innovative concepts, it has unique advantages in the production of Sanxiang acetaminophen naproxen sodium. Its products are not only reliable in quality, but also innovative in dosage forms to meet the needs of different patients.
    Shandong Xinhua Pharmaceutical joint stock company has a long reputation. It has a long history and profound accumulation. It is based on the pharmaceutical process and has extraordinary heritage. For the production of Sanxiang acetaminophen naproxen sodium, inherit the classics and combine modern technology to ensure the efficacy and safety of medicines. Its production scale is huge and the supply is wide, relieving the pain of many patients.
    In addition, Sichuan Kelun Pharmaceutical joint stock company is also listed. Kelun Pharmaceutical, with strong strength, pays attention to the coordination of research and development and production. In the production process of Sanxiang acetaminophen naproxen sodium, it strictly controls the quality control, produces high-quality drugs with advanced equipment and scientific management, and occupies an important place in the market competition.
    All these factories are important manufacturers of Sanxiang acetaminophen naproxen sodium. With their respective advantages, they contribute to the pharmaceutical industry and protect the health of patients.