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4-Fluoronitrobenzene

4-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code

678046

Chemical Formula C6H4FNO2
Molar Mass 141.1 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 205 - 207 °C
Melting Point -20 °C
Density 1.392 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents
Odor Characteristic aromatic odor
Flash Point 89 °C
Refractive Index 1.532

As an accredited 4-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle packaging for 4 - fluoronitrobenzene chemical.
Storage 4 - fluoronitrobenzene should be stored in a cool, well - ventilated warehouse. Keep it away from sources of ignition and heat. Store it separately from oxidizing agents, reducing agents, and other incompatible substances. Ensure containers are tightly sealed to prevent leakage. Regularly check storage conditions to maintain its stability.
Shipping 4 - fluoronitrobenzene is shipped in tightly - sealed, corrosion - resistant containers. It's transported by specialized carriers following strict hazardous material regulations to ensure safe transit and prevent environmental and safety risks.
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4-Fluoronitrobenzene 4-Fluoronitrobenzene
General Information
Historical Development
4-Fluoronitrobenzene is an organic compound. Its beginning can be traced back to the beginning of chemistry in the past. At that time, Zhu Xian studied the technique of organic synthesis, and gradually obtained the preparation method of this compound during the exploration.
At the beginning, the preparation method was simple and difficult, and the yield was quite low, which was only explored by Zhu Xian on the desk. However, years have passed, science and technology have advanced, and the preparation process has been improved again and again. Chemical craftsmen have worked hard to optimize the process and develop new agents to promote the effect of reaction.
Today, 4-fluoronitrobenzene is widely used in the chemical field. It can be used as a raw material for synthetic medicine or in the preparation of pesticides. Its historical evolution, just like a long river boat, began at the end of the micro, until now, in the chemical industry territory, occupy a place for future generations more research and pave the way.
Product Overview
4-Fluoronitrobenzene is also an organic compound. Its color is light yellow, oily, and has a special smell.
This compound is widely used in the chemical industry. It can be used as an intermediate for the synthesis of a variety of drugs, dyes and pesticides. In drug synthesis, it is a key raw material and helps to form many special drugs. In the manufacture of dyes, it can add unique color, making the dye more colorful and fastness better. It is also indispensable in the creation of pesticides, contributing greatly to the effect of pesticides.
However, it is dangerous. Toxic, if accidentally touched or inhaled by the human body, it may endanger health. And it is flammable, and it is easily dangerous when exposed to open flames and hot topics. Therefore, during production, storage, and use, it is necessary to adhere to safety procedures and take protective measures to ensure the safety of personnel and the environment.
Physical & Chemical Properties
4 - Fluoronitrobenzene is an organic compound, and its physical and chemical properties are very important. Looking at its properties, it is mostly colorless to light yellow liquid at room temperature, with a special odor. Its boiling point is quite high, about 205 ° C, which is caused by intermolecular forces. The melting point is about -7 ° C, indicating that it can be solid at low temperatures.
When it comes to solubility, it is slightly soluble in water, but easily soluble in most organic solvents, such as ethanol, ether, etc. This is because its molecular structure contains hydrophobic groups. Its density is greater than that of water, about 1.39 g/cm ³.
In terms of chemical properties, fluorine atoms and nitro groups on the benzene ring make the molecule have certain reactivity. Nitro groups have strong electron-absorbing properties, which reduce the electron cloud density of the benzene ring, which is conducive to nucleophilic substitution reactions. Although fluorine atoms have high electronegativity, the substitution reaction conditions are relatively harsh due to the large fluorocarbon bond energy. This compound has a wide range of uses in the field of organic synthesis and can be used as a synthetic raw material for many fine chemicals.
Technical Specifications & Labeling
There is now a method for making 4-Fluoronitrobenzene, and its technical specifications and identification (product parameters) are the key. To make this product, first take an appropriate amount of nitrobenzene, and add fluoride with a specific instrument under precise temperature control. When reacting, strictly observe the parameters of temperature and pressure, both of which are essential to the success or failure of the product. After the reaction is completed, multiple separation and purification techniques are used to remove impurities and retain essence. The resulting product needs to be tested according to strictly marked product parameters, such as its color, purity, and density. If the parameters are in line with the established specifications, it is a good product and can be used in all applications. In this way, the technical specifications and identification (product parameters) of 4-Fluoronitrobenzene are well observed to ensure the excellence of quality.
Preparation Method
4 - Fluoronitrobenzene is an important compound in organic synthesis, and its preparation method is crucial. In the selection of raw materials, fluorobenzene and nitric acid are often used as the initial materials. In the synthesis process, fluorobenzene is first placed in a reactor, and the mixed acid (the mixture of nitric acid and sulfuric acid) is slowly added dropwise in a low temperature environment. The key to this reaction step is to strictly control the temperature and dropwise rate to prevent side reactions from occurring. The
reaction process follows an electrophilic substitution mechanism. Nitric acid generates nitroyl positive ions under the action of sulfuric acid. This positive ion attacks the benzene ring of fluorobenzene and is rearranged by electron cloud to generate 4 - Fluoronitrobenzene. After the reaction is completed, the product is purified by washing with water, alkali washing, and distillation to remove impurities and improve the purity of the product. In this way, by carefully adjusting the raw materials and processes, following the established reaction steps and catalytic mechanisms, high purity 4-Fluoronitrobenzene can be obtained.
Chemical Reactions & Modifications
In recent years, the method of chemical research has been studied in the transformation and modification of 4-Fluoronitrobenzene. The transformation of this substance should be changed to the method of nitrate substitution and halogenation. However, traditional methods often suffer from low rate and heavy pollution.
We have sought new methods, thinking of catalysis to change the way of transformation. Choose a special catalyst to adjust the temperature and pressure, hoping to increase the reaction rate and reduce the generation of side reactions. After repeated tests, with a new type of metal complexation catalysis, at appropriate temperature and pressure, the reaction rate of 4-Fluoronitrobenzene increased significantly, and the side products decreased greatly.
As for modification, add specific functional groups, adjust its molecular structure, and change its properties. The method of adding hydroxyl groups increases its water solubility and expands its use area. This method should be used in the product R & D of 4-Fluoronitrobenzene, which may be of great use. It is a new way for the chemical industry and has achieved great results.
Synonyms & Product Names
4 - Fluoronitrobenzene, the synonym and trade name of this substance, is quite important in the field of chemical industry. As far as synonyms are concerned, there may be those who are called fluoro-nitrobenzene, "fluoro" means that it contains fluorine atoms, and "nitrobenzene" indicates its main structure. It may also be named for p-fluoronitrobenzene, and the word "pair" indicates the relative position of fluorine atoms and nitro groups in the benzene ring.
When it comes to trade names, in the chemical market, there may be those who are called by a specific trade name plus 4 - Fluoronitrobenzene, which is the merchant's product characteristics and brand. Or it may be called by a code name, which is convenient for industry communication and identification. So many synonyms and trade names refer to this thing precisely by chemical industry professionals in the context of research and development, production, and trade, in order to facilitate the smooth operation of the industry.
Safety & Operational Standards
4 - Fluoronitrobenzene is a chemical substance, which needs to be detailed in terms of its safety and operating practices.
Its nature is risky. This substance is toxic. If it is accidentally touched, whether it is skin contact, inhalation of its gas, or accidental ingestion, it can cause damage to the human body. In the skin, or cause redness, swelling, itching, burning; into the respiratory tract, it can cause cough, asthma, breathing difficulties, and even endanger lung function; if taken by mistake, it can hurt the stomach, cause severe pain, vomiting, diarrhea, and in severe cases, it can endanger life. And it is flammable, and it is very easy to explode when exposed to open flames and hot topics. In storage and use, the source of fire must be strictly controlled.
During operation, the specifications must be strictly adhered to. Operators should be professionally trained and familiar with their characteristics and emergency response methods. When working, protective equipment is indispensable, such as wearing protective clothing, protective gloves, and gas masks to ensure their own integrity. The operating environment needs to be well ventilated to prevent gas accumulation. When taking it, the action should be steady and accurate to avoid spillage. If there is a spill, do not panic, and dispose of it quickly according to the established process. First isolate the site, prohibit unrelated people from approaching, and then use suitable materials to absorb or clean it, collect and dispose of it properly, and do not discard it at will to cause environmental pollution.
Storage is also exquisite. It should be stored in a cool and ventilated place, away from fire and heat sources. It should be placed separately from oxidants and edible chemicals, and should not be stored together. Warehouses should be equipped with suitable materials to contain leaks.
The safety and operating standards of 4-Fluoronitrobenzene must not be ignored, so as to ensure the safety of personnel, protect the environment from harm, and be smooth in chemical research and production.
Application Area
4-Fluoronitrobenzene is an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key raw material. With its unique structure, it can undergo various reactions to obtain a variety of specific drugs and cure various diseases.
In the process of pesticide preparation, 4-fluoronitrobenzene is also indispensable. Through ingenious chemical changes, it can become an efficient pesticide, protect crops, resist pests, and ensure a bumper harvest.
In addition, in the dye industry, it also has an important position. By participating in the reaction, colorful dyes can be made, dyeing fabrics and bright colors, which will not fade for a long time.
All these show that 4-fluoronitrobenzene has extraordinary value in many application fields and contributes greatly to the development of chemical industry.
Research & Development
In recent times, the art of chemistry has become more and more refined, and various compounds have emerged in an endless stream. The research and development of 4 - Fluoronitrobenzene is quite important to our generation.
At the beginning, when exploring this compound, the synthesis method was difficult and the yield was quite low. However, many researchers have worked hard and worked tirelessly. After years of hard work, many experiments and improvements have been made in reaction conditions and catalyst selection.
Looking at its development today, the synthesis path has been gradually optimized, and the yield has also been greatly improved. Its application in medicine, materials and other fields is gradually widening. In medicine, to help the development of new drugs; in materials, or as a key component of materials with special properties. We should continue to move forward with the legacy of the Holy Spirit, hoping that this compound will have more outstanding development in the future, be used by the world, and benefit all beings.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons should not be careless. In today's words 4 - Fluoronitrobenzene, the study of its toxicity is quite important.
4 - Fluoronitrobenzene has the structure of aromatic hydrocarbons, and fluorine and nitro are attached. The nature of aromatic hydrocarbons is inherently poisonous, and fluorine and nitro are added, and the toxicity becomes more severe. Its entry into the body, either through breathing, or through skin contact, can cause harm. In the lungs, it hinders its ability to breathe; in the blood, it disturbs the blood cells. Or it damages the nerves, making people lose their minds and limbs weak.
Therefore, when studying its toxicity, we should carefully investigate the path of its entry into the body and the reason for harming the body. Only in this way can we understand its harm, take measures to prevent it, protect the practitioners and the surrounding people from its poison, and enable the chemical industry to proceed safely.
Future Prospects
In the future world, science and technology will change day by day, 4 - Fluoronitrobenzene This thing will have a wide range of uses. It can be used in the way of medicine, or it can assist in the research of new drugs, heal serious diseases, and save thousands of patients from pain. In the field of materials, it can give birth to strange materials, making utensils strong and light, and used in aviation industries to travel the sky. In chemical industry, it can also be a precursor, introducing new processes and producing exquisite products. Although it has been used today, the future will be like the rising sun, the light will be more prosperous, opening up endless new frontiers, and expanding the well-being of mankind. It will paint a gorgeous picture and expand the future of infinite possibilities.
Where to Buy 4-Fluoronitrobenzene in China?
As a trusted 4-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-fluoronitrobenzene?
Although 4-hydroxyquinoline was not as widely recognized in the era covered by "Tiangong Kaiwu" as in modern times, it is speculated from a modern perspective that its use may be related to some processes at that time.
In the field of traditional medicine, although the specific structure and efficacy of 4-hydroxyquinoline may not be clearly known at that time, some natural plants may contain similar structural components or be used for simple medicinal attempts. In ancient times, doctors often sought cures from natural plants and trees, and some plants containing similar structures of 4-hydroxyquinoline may have been used to treat some common diseases, such as clearing heat and detoxification.
In terms of dyes, 4-hydroxyquinoline or its related compounds may become potential components in the extraction process of ancient dyes. Ancient dyeing workshops mostly extracted dyes from natural plants and minerals. If the raw materials used contain 4-hydroxyquinoline structure, under specific extraction processes, they may be able to dye fabrics with unique colors. For example, some special plants contain similar ingredients that may have a dyeing effect on fabrics after soaking, boiling and other processes, and the dyed fabrics may have unique performance in terms of color durability.
In terms of metallurgical aids, in the development of ancient metallurgical technology, in order to make the metal smelting effect better, various additives were often used. Some chemical properties of 4-hydroxyquinoline may play a role in the metallurgical process, such as helping to separate impurities and improve metal properties. Although its chemical structure was not clear at that time, in long-term practice, or by chance, substances containing such components were found to be helpful to metallurgy and used.
What are the physical properties of 4-fluoronitrobenzene?
4-Isoquinoline is a chemical compound with many physical properties. Its white to light crystalline powder is usually solid under normal conditions, and the melting time is between 70 and 73 ° C. This characteristic makes it suitable for solid solution under specific conditions. It is especially valuable in material synthesis and some chemical reaction process control.
4-Isoquinoline has a high boiling time of 267 ° C, indicating that its molecular force is low. The high boiling properties make it have good quality in normal conditions, and it is not easy to be damaged due to low temperature waves. It is important for phase products that need to be stored or used in normal conditions.
In terms of solubility, 4-Isoquinoline is slightly soluble in water, and is easily soluble in ethanol, ether, chloroform, etc. This difference in solubility is due to the fact that the molecule contains both a hydrophobic quinoline group and a hydrophobic quinoline group, which makes it different in different solubility. The first characteristic can be used as an important basis for the separation, extraction and preparation of solution products.
In addition, 4-quinoline has certain optical properties. Because of the existence of a co-system of molecules, it can absorb specific waves of ultraviolet light and produce light under specific conditions. This optical property makes it useful in the fields of optical materials, optical detection, etc., and researchers can use this property to generate energy for specific substances or environmental transformation.
Furthermore, 4-quinoline crystals are integrated, and the molecules are arranged in an orderly manner through interactions. Crystal properties such as hardness and density also have an impact on its physical properties. In terms of crystal engineering and solid materials, the crystalline properties of 4-quinoline can provide a foundation for the construction of new functional materials.
What are the chemical properties of 4-fluoronitrobenzene?
4-Hydroxyquinolinyl boron, this physical property is special. It is an organic boron compound with a unique structure. It is connected by a quinoline ring to a boron atom through a hydroxyl group, giving it specific chemical properties.
On its stability, due to the conjugate system of the quinoline ring, the structure is relatively stable. However, the activity of the hydroxyl group is high, which can increase the reactivity. In case of electrophilic reagents, the hydroxyl oxygen is easy to supply electricity, which increases the activity of the boron check point and induces an electrophilic substitution reaction.
In terms of solubility, because the molecule contains polar hydroxyl groups and non-polar quinoline rings, it has a certain solubility in polar organic solvents such as ethanol and acetone, but has a low solubility in non
Optically, the conjugated structure of the quinoline ring gives it fluorescence properties. Under the excitation of light at a specific wavelength, electrons transition to high energy levels and emit light when they return to the ground state, which can be used in the fields of fluorescent probes, luminescent materials, etc.
Reactive activity is quite high. Hydroxyl groups can participate in esterification and etherification reactions; boron atoms have empty orbitals and can be used as Lewis acids to form complexes with molecules containing lone pairs of electrons such as amines and phosphines. This property has potential applications in the field of catalysis and can catalyze organic reactions, such as Diels-Alder reactions, Friedel-Crafts reactions, etc.
4-hydroxyquinoline-based boron has unique chemical properties and has broad application prospects in materials science, medicinal chemistry, catalytic chemistry and other fields, which need to be further explored and explored.
What is the production method of 4-fluoronitrobenzene?
4 - The method of cutting calamine is obtained by crushing calamine and calcining it.
The steps are as follows: First take the high-quality calamine, and wash it with clean water to remove the sediment. To be washed and dried, place it in a special crucible. This crucible needs to be carefully made of fire-resistant clay and other materials, which can withstand high temperatures without burning.
And then, under the crucible, a raging charcoal fire is ignited, and the fire is calcined. Calcined, you need to pay close attention to the size of the heat and the shortness of the heat. The fire is weak, and the calamine can be fully melted; the fire is fierce, and it is feared that it will be damaged. It usually takes a long time to calcine the calamine with a suitable fire, until the calamine is of the color of the calamine, and the calcined stone is in place.
After calcining, quickly remove the crucible and place it in a good natural cold. When it is cold to normal, the calamine has been raw. Take out the calamine from the cold, and crush it again with a pestle and mortar and other tools until it becomes a powder.
In this way, there are many steps such as washing, calcining, cooling, and grinding, so that the 4-calamine of the essence can be obtained for the use of calamine and other purposes. This method can only be perfected by generations without groping and changing it, and it can be improved day by day to achieve a good raw material.
What are the precautions for using 4-fluoronitrobenzene?
4-Hydroxyquinoline has many points to pay attention to during use. First, it is related to its solubility. 4-Hydroxyquinoline has low solubility in water, but it is soluble in some organic solvents, such as ethanol and acetone. When taking it, it is necessary to carefully select a suitable solvent according to specific needs to promote its full dissolution in order to achieve the desired use effect. If the solvent is not selected properly, it is very likely that it will not be evenly dispersed, which will affect the subsequent reaction or application effect.
Second, the stability cannot be ignored. The stability of this substance may be affected under light, high temperature and humid environments. Long-term light may cause its structure to change, resulting in reduced performance; under high temperature conditions, it may accelerate its decomposition; and humid environment is easy to make it absorb moisture, causing adverse effects on purity. Therefore, when storing, it should be selected in a cool, dry and dark place, properly stored, and sealed to prevent excessive contact with air and moisture.
Third, 4-hydroxyquinoline has a certain biological activity and is widely used in medicine, pesticides and other fields. However, it is because of its biological activity that it is necessary to pay close attention to its potential impact on the human body and the environment during use. In medicine, when used in drug synthesis, it is necessary to strictly control the dose and method of use, and fully consider the possible side effects and pharmacological reactions to ensure the safety of medication. When used in the field of pesticides, it is necessary to pay attention to its impact on non-target organisms, avoid unnecessary damage to the ecological environment, such as harm to beneficial insects and aquatic organisms, and strive to minimize its negative effects.
Fourth, the chemical reaction characteristics are extremely critical. In the molecular structure of 4-hydroxyquinoline, both the hydroxyl group and the quinoline ring have specific reactivity and can participate in many chemical reactions, such as substitution reactions, oxidation reactions, etc. When performing related reactions, it is necessary to precisely control the reaction conditions, such as temperature, pH, reaction time, and the proportion of reactants. If the reaction conditions are slightly deviated, different products may be generated, or the reaction yield may be low. For example, excessive temperature may cause side reactions and generate impurities, which may interfere with the acquisition of the main product; improper pH control may also affect the reaction rate and product selectivity. Therefore, its chemical reaction characteristics must be deeply understood and carefully controlled during use.