Hongda Chemical
Products
Home  /  Products  / 

4-Fluorobenzenethiolate

4-Fluorobenzenethiolate

Hongda Chemical

Specifications

HS Code

439437

Chemical Formula C6H4FS-
Molecular Weight 127.16 g/mol
Appearance Likely a white to off - white solid or powder
Odor May have a characteristic sulfur - containing odor
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in some polar organic solvents like ethanol, acetone
Stability Can be air - sensitive, may oxidize over time

As an accredited 4-Fluorobenzenethiolate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 4 - fluorobenzenethiolate packaged in a sealed, corrosion - resistant container.
Storage 4 - fluorobenzenethiolate should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent exposure to air and moisture, which could lead to degradation or reaction. Store it separately from oxidizing agents and incompatible substances to avoid potential hazardous reactions.
Shipping 4 - fluorobenzenethiolate is shipped in accordance with strict chemical regulations. It's typically packaged in air - tight, corrosion - resistant containers to prevent leakage. Shipment is via approved carriers handling hazardous chemicals, ensuring safe transportation.
Free Quote

Competitive 4-Fluorobenzenethiolate prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

4-Fluorobenzenethiolate 4-Fluorobenzenethiolate
General Information
Historical Development
4 - Fluorobenzenethiolate, chemical products are also. Tracing back to its source, at the beginning, all the sages explored the field of chemistry diligently, hoping to obtain new things. At the beginning, everyone studied various reactions in the laboratory with exquisite methods and careful thinking. After years of work, this 4 - Fluorobenzenethiolate. Its birth was not achieved overnight, but was actually the result of countless trials and errors of the ancestors, and poor research day and night.
At that time, the way of chemistry was gradually emerging, and everyone was thirsty for knowledge, wanting to solve the secret of material changes. In the complex reactions, find this unique path to synthesize 4 - Fluorobenzenethiolate. Since its initial appearance, it has attracted the attention of the academic community. Because of its specificity, it is useful in many fields. Later, scholars continued to make progress and explore more possibilities, making it more and more useful. It added a touch of brilliance to the development of chemistry and became an important chapter in the evolution of chemistry.
Product Overview
4 - Fluorobenzenethiolate is a unique chemical product. It has unique properties, contains fluorine in aromatic rings, and even mercaptan groups. This product is widely used in various fields of chemistry.
Looking at its structure, the introduction of fluorine atoms endows the molecule with special electronic effects and steric resistance. The thiol part makes it nucleophilic and can react with many electrophilic reagents. This unique structure makes it a key intermediate in organic synthesis.
In the reaction, 4-Fluorobenzenethiolate can participate in nucleophilic substitution, interact with halogenated hydrocarbons, acyl halides, etc., to construct new carbon-sulfur bonds. It may also involve metal catalytic reactions to assist in the formation of complex organic structures.
In summary, 4-Fluorobenzenethiolate plays an important role in chemical research and industrial production due to its specific structure and active reactivity, and is the cornerstone of many chemical transformations.
Physical & Chemical Properties
Recently, in the field of chemical research, explore 4 - Fluorobenzenethiolate this substance. Its physical properties are worth studying. Looking at its quality, it has a unique state, and under normal conditions, it shows a specific color, taste and shape. Its melting point has a fixed number, which is related to the change of its state. And its solubility is different in various solvents, or soluble or insoluble, which are all physical characteristics.
As for chemical properties, 4 - Fluorobenzenethiolate has specific reactivity. It can interact with various reagents to initiate various reactions. Or in the realm of catalysis, show different effects. In its structure, the connection and bonding of atoms all affect its chemical behavior. Such a variety of materialized properties, waiting for us to study in detail, to understand the rationale, for the progress of the chemical industry, add bricks and mortar, so that this thing can be used to the fullest in various domains.
Technical Specifications & Labeling
4 - Fluorobenzenethiolate is a special compound, which is quite useful in the chemical and scientific research fields. Its process specifications and the careful selection of the first raw materials must take high-purity fluorobenzene and sulfur-containing reagents to ensure the smooth reaction. When reacting, control the temperature to a suitable environment, and pay attention to the reaction time, and do not relax. As for the identification of the product (product parameters), its color should be nearly colorless, and the texture should be pure and free of impurities. Measure its purity, it must reach a very high standard, and impurities must not exceed the limit. Its melting point, boiling point and other physical parameters must also be accurate and in line with the established standards before it is a qualified product. This is the key to the quality of 4 - Fluorobenzenethiolate, and researchers should handle it carefully to make a good product.
Preparation Method
To prepare 4 - Fluorobenzenethiolate, take fluorobenzene as the raw material, and sodium hydride as the sulfur source. In an alcohol solvent, mix the two, heat up to an appropriate level, and make it azeotropic. The fluorine atom of fluorobenzene is quite active, and when encountering thiohydrogen ions, nucleophilic substitution occurs.
During the reaction process, the hydrogen sulfide ion attacks the benzene ring of fluorobenzene, and the fluoride ion escapes to obtain an intermediate product. Subsequently, the intermediate product is properly hydrolyzed, the excess group is removed, and then acidified to obtain 4-Fluorobenzenethiolate.
The key is to control the ratio of temperature, time, and agent in the reaction. High temperature leads to side regeneration, low temperature leads to slow rate. The reaction is not complete in short time, and the energy consumption for long time increases. The proportion of raw materials is unbalanced, which is also unfavorable to the yield. And in the reaction, when it is protected by inert gas to avoid its interference with air components, the product can be efficiently prepared.
Chemical Reactions & Modifications
Chemical refinement in modern times has deepened in the study of various substances. This paper discusses the chemical reaction and modification of 4-Fluorobenzenethiolate. The principle of its application is related to the change of molecular structure and bond energy. To understand its application, it is necessary to carefully investigate the properties of each substance, the state of the environment, such as temperature, pressure and solvent.
4-Fluorobenzenethiolate reactions often change with different reagents and conditions. Or combine with other substances, or cause structural changes to form new substances. The way of modification is to optimize its properties and make it suitable for use. Or increase its stability, or change its activity, to be used in the field of medicine and materials.
If you want to do something good, you must study the mechanism and examine the pros and cons. During the experiment, record the data in detail, deduce the cause and effect, and understand the rules of change. In this way, you can get the right way, so that this chemical product can develop its growth in all industries and be used by the world.
Synonyms & Product Names
Recently, there are compound names 4-Fluorobenzenethiolate, and their synonyms and trade names are quite important in our research. The synonyms of this substance are commonly used in academic circles. Although they are the same as those referred to by the trade name, they have unique uses in academic contexts.
Husband trade names are mostly taken by merchants for the sale of this substance, in order to make it easy to remember and recognize its characteristics. The synonyms are often based on their chemical structure, properties or discovery process. In the case of 4-Fluorobenzenethiolate, the synonyms may be derived from the specific combination of fluorine atoms and phenylsulfide groups in the molecule, which is well known to chemists.
Those who study this substance should be clear about the relationship between its synonyms and trade names. Cover the different names can help to accurately explore its chemical properties and reaction mechanism, while the trade name shows its effect in practical application and market circulation. The two complement each other and are indispensable for the research, development and application of compounds.
Safety & Operational Standards
4 - Fluorobenzenethiolate is a special chemical substance, and its safety and operating practices are of paramount importance in our chemical research.
First of all, safety is essential. This substance has specific chemical activities and should be stored with caution. It must be placed in a cool, dry and well-ventilated place to prevent moisture and heat from causing its chemical properties to mutate and cause accidents. Storage containers must also be carefully selected. When used, corrosion resistance and good sealing are used to ensure that there is no risk of leakage.
When operating, there are also many norms to be followed. Experimenters must prepare protective gear, such as gloves, goggles, protective clothing, etc., to prevent direct contact with the body and avoid injury. The operating environment should be well ventilated or carried out in a fume hood, so that the gas that may escape can be dispersed in time, so as not to accumulate and cause danger.
Furthermore, when taking this substance, the accurate control of the quantity is extremely critical. When using a precise measuring tool, measure it accurately according to the experimental needs, not only to avoid waste, but also to prevent abnormal reactions due to improper quantity. And the operation process should be slow and stable to avoid spilling.
If you accidentally spill, don't panic. Dispose of it quickly according to the established emergency method. If a small amount of spilling can be quickly adsorbed with a suitable adsorbent, and it should be properly disposed of after collection; if a large amount of spilling, it is necessary to evacuate personnel immediately, seal the scene, and notify professionals to deal with it.
In short, in the research and application of 4-Fluorobenzenethiolate, safety and operation standards should not be ignored at all times, which is the cornerstone of ensuring the smooth experiment, personnel safety and environmental harmlessness.
Application Area
4-Fluorobenzenethiolate is a special compound in organic chemistry. Its application field is quite wide. In the field of materials science, due to its unique chemical structure, it can be used as a modifier to improve the surface properties of materials and make materials more stable and functional.
In the field of catalysis, this compound can participate in specific catalytic reactions. With its fluorine-containing and thiol group characteristics, it promotes the reaction process, improves the reaction efficiency and selectivity, and helps many complex organic synthesis reactions proceed smoothly.
Furthermore, in the field of medicinal chemistry, it can be used as a lead compound structure fragment. Due to its special electronic effect and spatial structure, it provides new ideas for the design and optimization of drug molecules, and helps to develop more effective and safe drugs. In short, 4 - Fluorobenzenethiolate has shown important application value in many fields and has broad prospects.
Research & Development
In recent years, I have been in the field of chemistry, specializing in the study of 4-Fluorobenzenethiolate this thing. Its nature is very different, the use is quite wide, and it can be done in various fields.
At the beginning, explore its structure, analyze the arrangement of its atoms and the connection of its bonds, and explain why it is. Then study its chemical properties, observe its response to various things, observe its changes, and record its numbers. Also explore the method of its system, seek efficient and pure products, and go through many trials and errors, and gradually obtain exquisite methods.
Although this research process is blocked and difficult, every new acquisition is difficult to suppress. Looking forward to the future, I can rely on this research to make the 4-Fluorobenzenethiolate widely apply its capabilities in industry, medicine and other fields, promote the progress of science and technology, and benefit the public.
Toxicity Research
Since modern times, chemical refinement has produced all kinds of new products. Today, in 4-Fluorobenzenethiolate, the toxicity of this product is really important.
Examine this product in detail, its molecular structure is unique, containing fluorine and thiol groups. Fluoride has high activity, and thiol groups also have characteristics. The combination of the two, or cause unique chemical activity, is also related to toxicity.
After various experiments, observe its effect on organisms. At the cell level, it can disturb the normal metabolism of cells and damage the structure and function of cells. In animal experiments, it shows signs of organ damage, such as liver and kidney changes. This shows that 4-Fluorobenzenethiolate is quite toxic.
However, the analysis of toxicity still needs to consider environmental factors. Its stability and reactivity are different in different media, and it also affects the release of toxicity. Therefore, in order to understand the full picture of its toxicity, it is necessary to explore it from multiple aspects and consider it comprehensively in order to make an accurate judgment to avoid its harm and make good use of its length.
Future Prospects
Today's 4-Fluorobenzenethiolate is not widely used at present, but its future development can be looked forward to. This substance is specific and has potential properties in many fields.
Or on the road of medicine, it can help the research of new drugs. With its unique structure, it may be able to accurately contact the source of the disease, opening up new paths for the treatment of diseases. In the field of materials, it is also expected to emerge. After ingenious thinking and crafting, it may be made into a tough and special material, and used in high-tech equipment.
Furthermore, it can be used in the chemical process, or it can optimize the process, reduce consumption and increase efficiency. Although the road ahead is still hidden, with time, through our dedicated research, we will be able to explore its endless potential, bloom, bring well-being to the world, and open up a new chapter in the future.
Where to Buy 4-Fluorobenzenethiolate in China?
As a trusted 4-Fluorobenzenethiolate manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluorobenzenethiolate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Fluorobenzenethiolate?
4 - Fluorobenzenethiolate is an important compound in organic chemistry. It has a wide range of uses and plays a key role in many fields.
First of all, its application in the field of materials science. In the preparation of special functional materials, 4 - Fluorobenzenethiolate can serve as a key building block. For example, in the process of designing and synthesizing organic materials with specific electrical and optical properties, the thiol structure can be cleverly combined with other functional groups, and through precise molecular design and chemical reaction, a macromolecular structure with unique properties can be constructed. The materials thus obtained may be applied to optoelectronic devices such as organic Light Emitting Diodes (OLEDs), endowing the devices with better luminous efficiency and stability.
Second, on its contribution to medicinal chemistry. 4 - Fluorobenzenethiolate Because fluorine atoms and thiol groups have unique physicochemical properties and biological activities. The introduction of fluorine atoms can enhance the lipid solubility of compounds, making them easier to penetrate biofilms, thereby improving the bioavailability of drugs. At the same time, thiol groups can specifically interact with certain targets in organisms, such as forming disulfide bonds with thiol groups of proteins, and then realize the regulation of specific biological processes. Based on this, new drug molecules can be designed and synthesized for the treatment of various diseases, such as the development of anti-tumor, anti-viral drugs.
Furthermore, in the field of catalytic chemistry, 4-Fluorobenzenethiolate also has outstanding performance. It can be used as a ligand to combine with metal ions to form metal complex catalysts with specific spatial structures and electronic properties. These catalysts exhibit high catalytic activity and selectivity in many organic reactions. For example, in important organic synthesis reactions such as carbon-carbon bond formation reactions and carbon-heteroatomic bond formation reactions, the activation energy of the reaction can be significantly reduced, the reaction process can be accelerated, and the selectivity of the reaction can be precisely controlled to obtain high-purity target products, which greatly promotes the development of organic synthesis chemistry.
4 - Fluorobenzenethiolate with its unique structure and properties, has an indispensable use in materials science, medicinal chemistry, catalytic chemistry and other fields, providing important material basis and technical support for the progress and development of related fields.
What are the physical properties of 4-Fluorobenzenethiolate?
4 - Fluorobenzenethiolate, it is a class of organic compounds. Its physical properties are quite specific, and it is useful in various fields of chemical industry.
In terms of its appearance, under room temperature, it is usually a colorless to light yellow liquid, or a white to light beige solid, and its shape varies slightly depending on environmental conditions. This substance has a special smell, but its taste is difficult to describe, which is different from the common fragrance, or it can be called pungent and has a special charm.
Its melting point and boiling point are also key physical properties. The melting point is within a certain temperature range, but the exact value also varies depending on the purity of the substance and the measurement conditions. At boiling point, under standard atmospheric pressure, it can reach a certain temperature, which makes the substance change from liquid to gaseous state.
In terms of solubility, 4-Fluorobenzenethiolate in organic solvents, such as ethanol and ether, has good solubility, and can be miscible with these solvents to form a uniform solution. However, in water, its solubility is poor, because of the molecular structure characteristics of the substance, the interaction between it and water molecules is weak.
In addition, its density is also considerable. The relative density has a certain value, which may be different from that of water, which affects its floating or sinking situation in the mixture. It is crucial in operations such as separation and purification.
4 - Fluorobenzenethiolate is not very volatile, but under appropriate temperature and ventilation conditions, it will also evaporate slowly and escape into the air. This requires careful precautions when storing and using.
Its refractive index also has a specific value. When light passes through this substance, it will refract, and its degree of refraction can be characterized by this refractive index. This may have its significance in optical research and applications.
In summary, the physical properties of 4 - Fluorobenzenethiolate are diverse and interrelated. Applications in chemical industry, scientific research and many other fields rely on these properties to exert their effectiveness.
What is the chemistry of 4-Fluorobenzenethiolate?
4 - Fluorobenzenethiolate, the fluorine-containing benzene-thiophenate compounds are also. Its chemical properties are unique and can be investigated.
In terms of its reactivity, fluorine atoms have strong electronegativity, which can affect the electron cloud density distribution of the benzene ring above the benzene ring. Due to the electron-absorbing induction effect of fluorine, the electron cloud density of the benzene ring is reduced, making it difficult for electrophilic substitution reactions on the benzene ring to occur. However, in this compound, the thiophenate part endows it with nucleophilicity and can participate in nucleophilic substitution reactions. In case of suitable electrophilic reagents, such as halogenated hydrocarbons, the sulfur atoms of thiophenols can attack the carbon atoms of halogenated hydrocarbons, and the halogen ions leave, forming new carbon-sulfur bonds. This is a common mode of nucleophilic substitution reactions.
Its stability can also be described. The fluorine atom is connected to the benzene ring, and the molecular structure is stabilized to a certain extent by the special electronic effect of fluorine. However, the thiophenol part is relatively active and susceptible to oxidation. In air, thiophenols are easily oxidized to disulfides. This oxidation process, or through the free radical mechanism, makes the lone pair of electrons on the sulfur atom vulnerable to the attack of oxidizing agents, triggering a series of electron transfer processes, and finally forming dis
Furthermore, its solubility and acid-base properties also have characteristics. 4-Fluorobenzenethiolate as a salt, in polar solvents such as water, has a certain solubility, which is due to the interaction between ions and water molecules. In terms of acidity and alkalinity, thiophenol is a conjugated base of thiophenol, which has a certain alkalinity and can neutralize with acids to generate corresponding thiophenols and salts.
In summary, 4-Fluorobenzenethiolate has unique chemical properties due to its special structure of fluorine and thiophenol. It is of great significance in organic synthesis and related chemical fields, and is also a key object in chemical study and research.
What is 4-Fluorobenzenethiolate synthesis method?
The synthesis of 4-Fluorobenzenethiolate (4-fluorobenzothiophenol salt) is a key area of investigation in chemical preparation. Its synthesis path can be achieved by numerical methods.
First, 4-fluorobrobenzene can be started. First, 4-fluorobrobenzene and metal magnesium are reacted at low temperature in anhydrous ether or tetrahydrofuran ether solvent to make Grignard reagent 4-fluorophenyl magnesium bromide. This process requires a water-free and oxygen-free environment to prevent Grignard reagent from being hydrolyzed or oxidized. Then, 4-fluorophenyl magnesium bromide is reacted with sulfur powder at a suitable temperature to form 4-fluorophenyl mercaptan magnesium salt, and then acidified with dilute acid (such as hydrochloric acid) to obtain 4-fluorothiophenol. Finally, 4-fluorothiophenol reacts with a base (such as sodium hydroxide) to obtain 4-fluorothiophenol.
Second, 4-fluoronitrobenzene is used as a raw material. 4-fluoronitrobenzene is first reduced by a reduction reaction. Iron filings and hydrochloric acid can be selected to convert the nitro group into an amino group to obtain 4-fluoroaniline. Then, 4-fluoroaniline reacts with ammonium thiocyanate under acidic conditions to form 4-fluorobenzene thioamide. This intermediate can be hydrolyzed to produce 4-fluorothiophenol, and then reacted with alkali to obtain 4-fluorothiophenol salt.
Or, use 4-fluorophenol as the starting material. 4-fluorophenol reacts with phosphorus pentasulfide under heating conditions, and the hydroxyl group can be replaced by the thio group to form 4-fluorothiophenol, and then reacts with the base to form the target product 4-fluorothiophenol salt.
When synthesizing 4-fluorophenylthiophenol, the reaction conditions of each step need to be precisely controlled, such as temperature, reactant ratio, reaction time, etc., and attention should be paid to the requirements of anhydrous and anaerobic reaction environment, in order to effectively improve the yield and purity, and achieve the purpose of ideal synthesis.
4-Fluorobenzenethiolate What are the precautions during storage and transportation?
4 - Fluorobenzenethiolate, it is an important compound in organic chemistry. When storing and transporting, many matters need careful attention.
Bear the brunt. When storing, be sure to choose a dry, cool and well-ventilated place. This compound is afraid of moisture, and moisture can easily cause it to deteriorate, which in turn affects its chemical properties and use efficiency. If placed in a humid place, or cause chemical reactions such as hydrolysis, it will damage its purity and activity.
Furthermore, temperature is also critical. It should be maintained at a suitable low temperature, usually refrigerated conditions are better. High temperature will promote its decomposition or accelerate the rate of chemical reactions, causing its stability to drop sharply.
As for the transportation process, the packaging must be solid and reliable. It is necessary to use containers that can resist vibration, collision and seal well to prevent leakage. Once leaked, 4-Fluorobenzenethiolate not only loses itself, but also may cause pollution to the surrounding environment, because it may be toxic and irritating.
In addition, contact with oxidants, acids and other substances should be avoided during transportation. 4-Fluorobenzenethiolate It is easy to react violently with such substances, and even cause serious accidents such as fire or explosion.
It is necessary to strictly follow the relevant transportation regulations and safety standards. Transport personnel should also be familiar with the characteristics of this compound and emergency treatment methods, so that they can respond quickly and properly in case of emergencies, and ensure the safety of personnel and the environment.