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4-Fluorobenzene-1,2-Dicarboxylic Acid

4-Fluorobenzene-1,2-Dicarboxylic Acid

Hongda Chemical

Specifications

HS Code

556338

Chemical Formula C8H5FO4
Molar Mass 184.12 g/mol
Appearance Solid
Color White to off - white
Odor Odorless (usually)
Melting Point 205 - 209 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
Pka Values Multiple pKa values related to carboxylic acid groups
Density Data may vary, but typically in the range of organic acids

As an accredited 4-Fluorobenzene-1,2-Dicarboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - fluorobenzene - 1,2 - dicarboxylic acid packaged in a sealed plastic bag.
Storage 4 - fluorobenzene - 1,2 - dicarboxylic acid should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances. Store in a tightly closed container to prevent moisture absorption and potential degradation. Avoid storing near strong oxidizing agents or bases to maintain its chemical integrity.
Shipping 4 - fluorobenzene - 1,2 - dicarboxylic acid is shipped in well - sealed containers, compliant with chemical transportation regulations. Packaging safeguards against leakage and damage during transit to ensure safe delivery.
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4-Fluorobenzene-1,2-Dicarboxylic Acid 4-Fluorobenzene-1,2-Dicarboxylic Acid
General Information
Historical Development
4-Fluorobenzene-1,2-dicarboxylic acid is a product of chemistry. Its origin can be traced back to the time of research in the past. At that time, chemists studied the properties and changes of various substances with the heart of exploration. At the beginning, the understanding of this thing was still shallow, and only a few of its characteristics were seen.
With the passage of time, the research deepened. All the sages experimented with trial and error, analyzing its composition and exploring its structure with exquisite methods. Every attempt is like a candle in the dark night, gradually revealing the mystery of this thing. Finally, I have an understanding, and I understand the method of its preparation and the wonderful performance. Since then, 4-fluorobenzene-1,2-dicarboxylic acids have emerged in the field of chemistry, laying the foundation for many subsequent studies and opening a new chapter. Its development process is a shining chapter in the history of chemical exploration.
Product Overview
4-Fluorobenzene-1,2-dicarboxylic acid is a key raw material for organic synthesis. Its appearance is white to off-white crystalline powder with stable properties. Under normal temperature and pressure, it is insoluble in water, but soluble in some organic solvents, such as ethanol, acetone, etc.
This compound has a unique chemical structure. The introduction of fluorine atoms in the benzene ring endows it with special physical and chemical properties. In the field of organic synthesis, it is often used to prepare various fluorinated fine chemicals, such as drugs, pesticides and materials.
There are many methods for synthesizing 4-fluorobenzene-1,2-dicarboxylic acid. The common ones are that specific fluorobenzene derivatives are used as starting materials and converted through multi-step reactions. The preparation process requires precise control of reaction conditions, such as temperature, pH, reaction time, etc., to ensure the purity and yield of the product.
Because of its broad application prospects in medicine, pesticide research and development and the creation of new materials, it is of great significance for its in-depth research and development, and is expected to promote technological innovation and progress in related fields.
Physical & Chemical Properties
4-Fluorobenzene-1,2-dicarboxylic acid (4-Fluorobenzene-1,2-Dicarboxylic Acid), also an organic compound. It has specific physical and chemical properties. Looking at its physical properties, under room temperature, it may be solid, white or nearly white, if crystalline, the pure one is crystal clear and shiny. Its melting point and boiling point are inherent numbers. The melting point is determined by the force between molecules. To a specific temperature, it is converted from solid to liquid, and this temperature can be used to identify. The boiling point is also the same. Under a specific pressure, it reaches a certain temperature and gasifies.
On its chemical properties, the genus of carboxyl groups, acidic, and can neutralize with bases to produce corresponding salts and water. The existence of fluorine atoms increases its reaction characteristics, which can involve various reactions such as nucleophilic substitution. In the field of organic synthesis, it has a wide range of uses. Its chemical stability also needs to be investigated. In case of different reagents, conditions, or stability or change, it is related to its structure and bond energy. Such properties are of great significance in many aspects such as chemical industry and pharmaceutical research and development, and are also carefully investigated by researchers.
Technical Specifications & Labeling
The technical specifications and identification (product parameters) of 4-fluorobenzene-1,2-dicarboxylic acid are related to this product, and it is necessary to indicate that the technical specifications are rigorous and the identification is accurate. The technical specifications of this product cover the selection of raw materials and the details of the process. The raw materials must be of high quality, with few impurities and high purity, in order to ensure the quality of the product. During the process, parameters such as temperature, duration, and ratio need to be precisely controlled. If the reaction temperature is maintained within a certain range, too high or too low can cause product quality changes.
Its identification (product parameters) is also crucial, and the ingredients, purity, and physical properties of the product should be clearly marked. The purity needs to meet specific standards, and the physical properties such as color and shape need to be accurately described. In this way, users can clearly understand the characteristics of the product, operate it correctly at the time of application, and ensure that the product plays its due role. This is also the key to ensuring product quality and market circulation.
Preparation Method
To prepare 4-fluorobenzene-1,2-dicarboxylic acid, the method is as follows:
First take the required raw materials, find fluorine and benzene ring-related substances, and have groups that can be converted into carboxyl groups. The choice of raw materials is a matter of success or failure, and its purity and activity need to be carefully considered.
When preparing, the first reaction step. Under appropriate reaction conditions, fluorine atoms are introduced to a specific position in the benzene ring, or by reacting with benzene derivatives with fluorine-containing reagents. This step requires temperature control and time control to make fluorine atoms precisely occupy the position. Then, try to introduce carboxyl groups into the ortho-position, and carboxyl groups can be added to the ortho-position of the benzene ring through specific organic reactions, such as appropriate halogenates, through multi-step reactions.
Furthermore, the catalytic mechanism is also crucial. Choosing the right catalyst may speed up the reaction rate and increase the yield. Its catalytic activity and selectivity have a great impact on the purity of the product. During the reaction, carefully observe the reaction process and adjust the parameters in a timely manner to ensure the smooth reaction. In this way, a relatively pure 4-fluorobenzene-1,2-dicarboxylic acid may be obtained, which is ready for subsequent use.
Chemical Reactions & Modifications
In a certain day's chemical plant, we focused on the research and development of fine chemicals. The reaction and properties of this compound, 4 - Fluorobenzene - 1,2 - Dicarboxylic Acid, are worth studying.
The method of the past, synthesizing this acid, is very inconvenient. The reaction conditions are harsh, it cannot be formed at non-high temperature and high pressure, and the yield is average and there are many impurities. The obtained product often needs complicated purification, which is time-consuming and laborious.
Today, we have worked hard, and the improved method has achieved initial results. With the new catalyst, the reaction conditions are gradually milder, and the normal temperature and pressure can also be improved. And the yield jumps, and the impurities decrease sharply. This change is of great benefit to the convenience of production and the control of cost. It is a blessing for chemical synthesis, and it may be widely used in the future to produce more high-quality chemicals.
Synonyms & Product Names
4 - Fluorobenzene - 1,2 - Dicarboxylic Acid, the synonym and trade name of this thing are quite elegant. In the field of my chemical research, exploring its synonyms is the key to clarifying its characteristics and uses.
This compound may be called fluorophthalic acid. The introduction of fluorine atoms makes the benzene ring and carboxyl group linked structure unique. Its trade name may vary depending on the manufacturer and use. In fine chemical production, it may be named after its unique properties, which is convenient for industrial application.
Looking at past studies, different literature or research perspectives have slightly different names for it. However, its essence refers to compounds of this specific structure. We chemical researchers need to carefully investigate the synonyms and trade names in order to use them accurately in experimental and production applications, so as to promote the progress of chemical research and industrial practice.
Safety & Operational Standards
4 - Fluorobenzene - 1,2 - Dicarboxylic Acid (4 - Fluorobenzene - 1,2 - Dicarboxylic Acid) is a chemical product we have been working on. Safety and operating standards are of paramount importance during its preparation and application, which is related to the safety of our researchers and endangers the success or failure of the experiment.
During the preparation of this compound, many chemical reagents react with it, and some reagents are toxic, corrosive or flammable. Therefore, when accessing various reagents, be sure to wear protective clothing, protective gloves and goggles to prevent the reagents from contacting the skin and eyes and causing irreparable damage. Operating in a well-ventilated environment can effectively avoid the accumulation of harmful gases and ensure respiratory safety.
Furthermore, the operation process needs to be strictly followed. From the ratio of raw materials to the control of reaction conditions, there are fixed numbers. Factors such as reaction temperature, time and stirring speed have a great impact on the purity and yield of the product. If the reaction temperature is too high, or side reactions occur, the product is impure; if the reaction time is insufficient, the yield is low. Therefore, it is necessary to precisely control each step and operate according to the experimental manual and established standards.
The use of experimental instruments should not be underestimated. Before use, check whether the instrument is in good condition, whether there are leaks, blockages, etc. After use, clean and maintain it in time to ensure normal use next time.
For storage, 4-fluorobenzene-1,2-dicarboxylic acid should be placed in a dry and cool place, away from fire sources and oxidants. Due to its active chemical properties, improper storage may cause safety accidents.
In conclusion, in the research work of 4-fluorobenzene-1,2-dicarboxylic acid, safety and operating standards are the first principles. Our researchers should always keep in mind and act with caution to ensure the smooth operation of the experiment and the desired results.
Application Area
4-Fluorobenzene-1,2-dicarboxylic acid is also a chemical product. The field of its use is quite wide. In the field of medicine, this compound can be used as a raw material to make special drugs, treat various diseases, and benefit people's health. In the field of materials, it can be added to the material to make it have special properties, such as increasing its toughness and resistance, and used in various instruments and utensils. In the dyeing and weaving industry, it can be used as the base of color materials, giving fabrics a fresh color and lasting. And in the road of scientific research, it is an important reagent, assisting researchers in exploring the secrets of chemistry and advancing science. Its role in various fields is becoming increasingly apparent, and it is valued by the world, which will open up more new possibilities for use and promote the flourishing of related industries.
Research & Development
4-Fluorobenzene-1,2-dicarboxylic acid, this compound has attracted much attention in our research. We have carefully studied its characteristics and explored its reaction under different conditions. After repeated trials, we have found that it can undergo unique transformation under the action of specific reagents.
We are committed to the expansion of this compound, hoping to develop more potential uses for it. Through exquisite synthesis strategies, we strive to improve its yield and purity. Through unremitting efforts, we have achieved initial results, and the yield has increased compared with the past.
Looking forward to the future, we will continue to explore 4-fluorobenzene-1,2-dicarboxylic acid in depth, and explore its application potential in materials science, drug development and other fields to promote the further development of this compound.
Toxicity Research
4-Fluorobenzene-1,2-dicarboxylic acid is also a chemical substance. It is essential for scientific research to detect its toxicity today. Among various substances, its appearance may be special, and its properties may also vary.
Examine this acid in detail, and observe its effect on various organisms between experiments. Try to place insects, plants and trees in the environment containing this substance, and observe the changes in their vitality and growth. See insects or abnormal behavior, vitality fades away; grass and trees change leaf color or change, growth is blocked.
It is also probed in the environment, or dissolved in water, or dispersed in air. If there is this acid in water, all aquatic things will be affected by it; if the gas contains this acid, the surrounding creatures will also suffer from it.
The study of toxicity is related to the safety of all things. It is necessary to examine its nature in detail and clarify its harm, in order to protect the environment and protect the living spirit. In the process of scientific research, the study of toxicity must not be ignored.
Future Prospects
4-Fluorobenzene-1,2-dicarboxylic acid is a chemical research substance. Its future prospects are particularly promising. In this substance, researchers hope to explore its more subtle properties. Or on the reaction mechanism, there can be new ways to make its synthesis method simpler, save time and effort, and reduce its cost.
It is expected to be used in the field of application and can expand to Xinjiang. Or in the field of materials science, emerging, for the creation of novel functional materials, to help its performance to meet all needs. Or in the field of medicine, its potential effect is discovered, as a medicine for treating diseases and treating patients. With unremitting research and development, this 4-fluorobenzene-1,2-dicarboxylic acid will shine in the future and benefit many fields.
Where to Buy 4-Fluorobenzene-1,2-Dicarboxylic Acid in China?
As a trusted 4-Fluorobenzene-1,2-Dicarboxylic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluorobenzene-1,2-Dicarboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-fluorobenzene-1,2-dicarboxylic acid?
4-Bromo-1,2-diacetic acid is an organic compound with unique properties and important uses in various fields.
This substance contains a bromine atom and a diacetic acid group. The bromine atom is active, making the compound easy to participate in the substitution reaction. If under appropriate conditions, the bromine atom is replaced by other functional groups, such as hydroxyl and amino groups, thereby preparing a variety of derivatives for the creation of medicines and pesticides.
Its 1,2-diacetic acid part contains a carboxyl group, which is acidic and can neutralize with bases to produce corresponding carboxylic salts. It can also be esterified with alcohols to obtain ester compounds. These esters are widely used in flavors, plasticizers and other industries.
In addition, the spatial structure and electronic effects of 4-bromo-1,2-diacetic acid affect its reactivity and selectivity. The interaction of various groups in the molecule, or the specific reaction check point, is more likely to participate in the reaction, providing a basis for the precise design of organic synthesis. In the organic synthesis process, controlling the reaction conditions and selectivity of 4-bromo-1,2-diacetic acid can effectively obtain the target product, improve the synthesis efficiency and yield.
4-bromo-1,2-diacetic acid has important value in many fields such as organic synthesis, materials science, and drug development due to its unique chemical properties, laying the foundation for the creation of new compounds and materials.
What are the main uses of 4-fluorobenzene-1,2-dicarboxylic acid?
4-Hydroxyquinoline-1,2-diacetic acid is an important organic compound that is widely used in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate in drug synthesis. Due to its unique chemical structure, it can interact with specific targets in organisms and has potential biological activity. For example, when developing anticancer drugs, the structure of this compound can be modified and modified to precisely act on the specific molecular pathways of cancer cells, so as to inhibit the proliferation of cancer cells and induce their apoptosis. In the creation of antibacterial drugs, its structural properties can also be used to destroy the cell wall or cell membrane of bacteria, thus exerting antibacterial functions.
In the field of materials science, 4-hydroxyquinoline-1,2-diacetic acid also shows unique value. It can participate in the preparation of functional polymer materials, and by virtue of its own chemical activity, it can react with other monomers to give polymer materials special properties such as fluorescence and adsorption. For example, the preparation of fluorescent polymer materials with selective identification ability for specific ions is used for highly sensitive detection of certain heavy metal ions in environmental monitoring; or the preparation of materials with high adsorption performance is used to treat industrial wastewater and adsorb harmful pollutants.
In the field of coordination chemistry, this compound can be used as a ligand to coordinate with metal ions to form complexes with diverse structures. These complexes often exhibit unique optical, electrical and magnetic properties. For example, complexes formed with transition metal ions may exhibit excellent catalytic properties, acting as efficient catalysts in organic synthesis reactions, reducing the activation energy of the reaction, improving the reaction rate and selectivity, and then promoting the development of organic synthesis chemistry.
From this perspective, 4-hydroxyquinoline-1,2-diacetic acid plays a pivotal role in many aspects such as medicine, materials, and coordination chemistry, and is of great significance to scientific research and industrial production in related fields.
What is the preparation method of 4-fluorobenzene-1,2-dicarboxylic acid?
To prepare 4-bromo-1,2-diacetic acid, you can do it according to the following method.
First take an appropriate amount of 1,2-dibromoethane and place it in the reactor. Add excess sodium cyanide to it, and under the action of appropriate temperature and catalyst, make the cyano group replace the bromine atom. The reaction formula is: $BrCH_ {2} CH_ {2} Br + 2NaCN\ stackrel {catalyst} {\ longrightarrow} NCCH_ {2} CH_ {2} CN + 2NaBr $. This step needs to pay attention to the precise control of the reaction conditions. Sodium cyanide is highly toxic, and the operation must be cautious.
When the reaction is fully completed, take out the product NCCH_ {2} CH_ {2} CN, put it in another reaction vessel, add an appropriate amount of dilute sulfuric acid and heat to promote the hydrolysis of cyanide to carboxyl groups, the reaction formula is as follows: $NCCH_ {2} CH_ {2} CN + 4H_ {2} O + 2H_ {2} SO_ {4}\ stackrel {\ triangle} {\ longrightarrow} HOOCCH_ {2} CH_ {2} COOH + 2NH_ {4} HSO_ {4} $.
So far, after this two-step reaction, 4-bromo-1,2-diacetic acid can be obtained. However, during the preparation process, the temperature, time, and proportion of reactants in each step of the reaction need to be carefully controlled, and the reagents used are often dangerous, such as sodium cyanide, which is highly toxic, and sulfuric acid, which is corrosive. Therefore, safety procedures must be strictly followed during operation, and protective measures must be taken to ensure the safety and success of the experiment.
What are the precautions for 4-fluorobenzene-1,2-dicarboxylic acid in storage and transportation?
4-Hydroxynaphthalene-1,2-diacetic acid is a commonly used raw material in chemical industry. During storage and transportation, many points should be paid attention to.
First words storage. This substance should be placed in a cool, dry and well-ventilated place. Cover because of its nature, if in a humid environment, it is easy to absorb moisture and deteriorate, causing its chemical properties to change, affecting subsequent use. And it must be kept away from fire and heat sources to prevent fire or other safety accidents. In addition, it should be stored separately from oxidants, acids, bases, etc., and cannot be mixed. It may chemically react with these substances, damage its own quality, and even generate dangerous products. At the same time, the storage area should be equipped with suitable materials to contain the leakage, in case of leakage, it can be dealt with in time.
Second talk about transportation. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. Summer transportation should be carried out in the morning and evening to avoid high temperature periods, because high temperature may cause it to evaporate or have unstable reactions. During transportation, it should be protected from sun exposure, rain and high temperature. Road transportation should be carried out according to the specified route, and do not stop in residential areas and densely populated areas. If it is rail transportation, it is also necessary to follow relevant regulations to ensure transportation safety. In short, whether storing or transporting 4-hydroxynaphthalene-1,2-diacetic acid, it is necessary to operate in strict accordance with regulations to ensure personnel safety and material quality.
What is the market price range for 4-fluorobenzene-1,2-dicarboxylic acid?
4-Hydroxyquine-1,2-diacetic acid, the price range of this product in the market is difficult to determine. The price often changes due to many reasons, such as the purity of the quality, the supply and demand of the market, the complexity and simplicity of the system, and the distance of transportation, etc., are all related to it.
If the quality is pure and refined, it is the best product, and it is popular in the market, but the supply is thin, and the production is complicated, and the transportation is long, the price will be high, or it can reach the realm of high prices. On the contrary, if the quality is slightly inferior, the market needs to be slow, and the system is easy and easy to transport, the price is relatively low.
I have heard that among the cities, the price is low, or to tens of dollars per catty; while the high, or up to hundreds of dollars per catty, or even more than a thousand dollars. However, these are all approximate values, which are realized in various places at all times, and the price may fluctuate up and down, making it difficult to generalize. To know the exact price, you must carefully consider the local market conditions at that time, and consult the industry and merchants to obtain a close estimate.