As a leading 4-Fluoro-Gamma-Oxo-Benzenepentanoic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 4-Fluoro-Gamma-Oxo-Benzenepentanoic Acid?
4-Fluoro-gamma-oxo-valproic acid, this is an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline powder, stable at room temperature and normal pressure.
In terms of solubility, slightly soluble in water, but soluble in organic solvents such as ethanol, ether, etc. This characteristic is derived from its molecular structure, containing polar carboxyl groups and non-polar benzene rings and fluorine atoms. The polar part interacts with water to a certain extent, but due to the limitation of the non-polar part, its water solubility is poor, and it is more soluble in non-polar or weakly polar organic solvents.
In terms of chemical activity, carboxyl groups can participate in many reactions. For example, it can neutralize with bases to form corresponding carboxylic salts and water, which is commonly used in regulating the pH of the system. It can also be esterified with alcohols under acid catalysis to form esters, which is a common method in organic synthesis to prepare fragrances, pharmaceutical intermediates, etc.
Its γ-oxo structure endows the compound with unique reactivity. This carbonyl group can undergo nucleophilic addition reactions, like reacting with Grignard reagents, introducing new carbon-carbon bonds, which is of great significance for the construction of complex organic molecular structures.
The presence of 4-fluorine atoms significantly affects the properties of compounds. Fluorine atoms are highly electronegative and have a strong electron-absorbing induction effect, which can change the distribution of molecular electron clouds, enhance acidity, and affect reaction activity and selectivity. In the field of medicinal chemistry, the introduction of fluorine atoms can often optimize the metabolic stability, fat solubility and target binding ability of drug molecules, and improve drug efficacy.
4-Fluoro-γ-oxo-benzovaleric acid has important applications in organic synthesis, drug research and development and other fields due to its unique chemical properties. It is a class of organic compounds worthy of in-depth study.
What are the main uses of 4-Fluoro-Gamma-Oxo-Benzenepentanoic Acid?
4 - Fluoro - Gamma - Oxo - Benzenepentanoic Acid, Chinese name or 4 - - γ - - phenylvaleric acid. This substance has a wide range of uses and is often a key intermediate in the synthesis of special efficacy drugs in the field of medicinal chemistry. Or because of its unique structure, it can interact with specific biological targets, helping to develop new anti-disease drugs, such as anti-tumor and anti-infection genera.
In the field of organic synthesis, it is an important starting material for the construction of complex organic molecular structures. Because of its functional groups, it can extend the carbon chain or introduce other functional groups through various chemical reactions, such as esterification, acylation, etc., to achieve ingenious construction of complex organic compounds.
In the field of materials science, there may also be a presence. After appropriate chemical modification, materials with special properties can be prepared, such as functional materials with adsorption or separation properties for specific substances, which is of great significance in the separation and purification of substances in chemical production.
This compound plays an indispensable role in many scientific and industrial fields due to its unique chemical structure, promoting sustainable development and innovation in various fields.
What is the synthesis method of 4-Fluoro-Gamma-Oxo-Benzenepentanoic Acid?
The synthesis of 4-fluoro - γ - -valproic acid is an important topic in the field of organic synthesis. Its synthesis method often follows several classical paths.
First, fluorine atoms can be introduced into the benzene ring by halogenation from the starting material containing the benzene ring. This halogenation reaction requires careful selection of halogenating reagents and reaction conditions in order to accurately locate fluorine atoms. For example, a suitable fluorinating agent can be selected to achieve the fluorination of the benzene ring in the presence of a specific catalyst at an appropriate temperature and reaction time.
Then, by constructing a carbon chain to generate the pentanoic acid moiety. This step can utilize strategies such as Grignard reagent reactions or nucleophilic substitution reactions. Taking Grignard's reagent as an example, the halogenated hydrocarbon can be reacted with magnesium to prepare Grignard's reagent, and then reacted with the corresponding carbonyl compound to grow the carbon chain, and then construct the valeric acid structure.
After the formation of the valeric acid carbon chain, a γ-oxo structure needs to be introduced. This can be achieved by oxidation reaction, for example, using a suitable oxidizer to oxidize the alcohol hydroxyl group at a specific position to a carbonyl group, thereby generating a γ-oxo-valproic acid moiety.
Another strategy is to start with the compound containing the valeric acid structure, first construct the benzene ring moiety, and then introduce the fluorine atom and γ-oxo structure. The method of introducing fluorine atom and γ-oxo structure in the construction of benzene ring can be used in classic reactions such as Foucault reaction, which is similar to the similar steps in the above strategy. It is necessary to precisely select the reaction reagent and optimize the reaction conditions according to the characteristics of the reaction substrate, the controllability of the reaction conditions and the purity requirements of the target product.
Synthesis of 4-fluoro - γ - -benzoic acid requires clever planning of the reaction path, fine regulation of the reaction conditions at each step, to ensure that each reaction is carried out efficiently and accurately, so that the target product can be obtained with high yield and purity.
What is the price range of 4-Fluoro-Gamma-Oxo-Benzenepentanoic Acid in the market?
4-Fluoro- - γ - -valproic acid, the price of this product in the market is difficult to determine. The fluctuation of its price is affected by various factors.
The market of chemical materials in the past, the abundance of raw materials has a huge impact on the price. If the raw materials required for the preparation of 4-fluoro- - γ - -valproic acid are well received in the place of origin and the supply is smooth, the price may be stabilized; on the contrary, if the raw materials encounter natural disasters, geopolitical disputes, etc., the production will be reduced and the supply will be in short supply, and the price will rise.
The simplicity of the process is also the key. If the method of synthesizing this acid is simple and efficient, the energy consumption and cost are low, and the market price should be close to the people; if the process is complicated, high-precision equipment and multiple steps are required, the cost will increase greatly, and the price will be high.
The supply and demand situation of the market, especially the left and right prices. If many industries have strong demand for 4-fluoro - γ - -benzoic acid, and the demand is too high, the merchant will raise the price to obtain high profits; if the demand is sluggish, the supply exceeds the demand, the merchant will stock up or reduce the price for promotion.
There is also the impact of competing products. If there are alternatives with similar performance and better price in the market, 4- - γ - -valproic acid can be used to maintain its share, or its price can be reduced as appropriate; if there is no threat of competing products, the price may be higher.
In summary, in order to know the exact price of 4-fluoro - γ - -valproic acid, it is necessary to carefully observe the raw materials, processes, supply and demand and competing products in real time, so as to have a more accurate judgment. However, based on the current information, it is difficult to determine the price range.
What are the storage conditions for 4-Fluoro-Gamma-Oxo-Benzenepentanoic Acid?
4 - Fluoro - Gamma - Oxo - Benzenepentanoic Acid is an organic compound, and the storage conditions of this substance are quite important. It should be stored in a cool, dry and well-ventilated place.
A cool environment can prevent its chemical properties from changing due to excessive temperature. Under high temperature, it may cause its decomposition and deterioration, which will damage the quality and utility of the compound. Therefore, choose a place with stable temperature and not too high, such as a constant-temperature greenhouse, and the temperature should be maintained between 15 and 25 degrees Celsius.
Dry conditions are also indispensable. Because moisture can react with the compound, or cause adverse reactions such as hydrolysis. The storage place must be moisture-proof, and desiccants, such as silica gel, can be used to absorb the surrounding water vapor to keep it dry.
Furthermore, good ventilation is essential. If the storage environment is not ventilated, the volatile gas of the compound will accumulate, which may increase the risk of fire and explosion, and is not conducive to human health.
In addition, the storage of 4 - Fluoro - Gamma - Oxo - Benzenepentanoic Acid should be kept away from fire, heat sources and strong oxidants. Because of its flammability, it is easy to catch fire and burn in case of fire and heat sources. Contact with strong oxidants or cause them to react violently, resulting in unpredictable consequences.
When storing, pay attention to sealing. If the seal is not good, the compound may react with air components such as oxygen and carbon dioxide, causing it to deteriorate. Container in an airtight container to reduce contact with external substances and maintain its chemical stability.
Handle the compound with care to prevent damage to the package and container. If the package is damaged, the compound may be exposed, or cause leakage, pollute the environment, and increase safety risks.
In the storage area, clear warning signs should be set up to inform personnel of the danger and operate with caution. Emergency treatment equipment and suitable containment materials should also be prepared to deal with sudden leaks and other situations.