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4-Fluoro Benzene Bonronic Acid

4-Fluoro Benzene Bonronic Acid

Hongda Chemical

Specifications

HS Code

473860

Chemical Formula C6H6BO3F
Molar Mass 155.92 g/mol
Appearance White to off - white solid
Melting Point 215 - 219 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
Pka Value Around 8 - 9
Density Approx. 1.42 g/cm³
Stability Stable under normal conditions, but moisture - sensitive

As an accredited 4-Fluoro Benzene Bonronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - fluoro Benzene Boronic Acid packaged in a sealed, moisture - resistant container.
Storage 4 - fluoro Benzene Boronic Acid should be stored in a cool, dry place away from heat and direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and contact with air, as it may react. Store separately from incompatible substances like strong oxidizing agents. Ideal storage temperature is generally around 2 - 8 °C if long - term stability is required.
Shipping 4 - fluoro Benzene Boronic Acid should be shipped in well - sealed containers, protected from moisture and heat. It must comply with all chemical transportation regulations, likely classified as a non - hazardous but sensitive chemical for careful handling during transit.
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4-Fluoro Benzene Bonronic Acid 4-Fluoro Benzene Bonronic Acid
General Information
Historical Development
4 - Fluoro Benzene Bonronic Acid, its origin is also known to everyone at the beginning. However, as the years go by, chemists have made great efforts to research, and gradually understand its properties and abilities. In the past, all the wise men were in the field of chemistry, overcoming thorns, with microscopic observations, accumulating soil and gathering sand, studying the change of matter. In various reactions, explore its traces, and know that it can be used in organic synthesis, which is a good material for creating new things. Therefore, its position in the chemical industry is growing day by day. With the passage of time, the technology is more refined, the preparation method is more and more complete, and the yield is gradually improved. From its beginnings of ignorance and exploration, 4-Fluoro Benzene Bonronic Acid has been widely used today. It has undergone transformation and left shining marks in the long river of chemistry, paving the way for future generations to research new creations. Its development process is a vivid portrayal of one of the evolutions of chemistry.
Product Overview
4 - Fluoro Benzene Bonronic Acid is also an organic compound. Its shape or white powder is quite stable. In the field of organic synthesis, it has a wide range of uses.
This compound contains fluorine atoms and boric acid groups, and has a unique structure. The introduction of fluorine atoms can change its physical and chemical properties. Boric acid groups are electrophilic and can participate in a variety of reactions, such as the Suzuki reaction. They can be coupled with halogenated aromatics to form carbon-carbon bonds, which are essential in drug synthesis and material preparation.
The preparation method is often obtained by starting from the corresponding halogenated aromatics and reacting in multiple steps. The reaction conditions need to be precisely controlled, and temperature, solvent, catalyst, etc. all affect the yield and purity.
4 - Fluoro Benzene Bonronic Acid research can open up a new path for organic synthesis, and it is also of great significance for the development of medicine, materials and other industries.
Physical & Chemical Properties
The physical and chemical properties of 4-fluorophenylboronic acid are particularly important. Looking at its state, it is mostly white crystalline at room temperature, pure and positive in color. Its melting point is quite high, about a certain range. This property can be relied on when separating and purifying.
When it comes to solubility, it has a certain solubility in common organic solvents, such as alcohols and ether solvents, which are soluble, but the solubility in water is relatively limited. This difference in solubility can be used to select a suitable reaction medium in chemical preparation and application.
Its chemical activity is also characteristic, and the fluorine atom and boric acid group on the benzene ring give it special reactivity. It can participate in many organic synthesis reactions, such as Suzuki coupling reaction, exhibiting unique chemical properties and broad application prospects in medicine, materials and other fields.
Technical Specifications & Labeling
This product of 4 - Fluoro Benzene Bonronic Acid, the process specifications and identification (commodity parameters) are the key. Its process specifications need to follow the delicate method. The raw materials must be selected with high quality, the proportion is accurate, the reaction conditions are strictly controlled, the temperature and duration are fixed, so that the reaction is sufficient and the purity of the product is guaranteed.
In terms of identification, the product parameters should be clear. From the appearance color, it should be pure color, without noise; to the amount of content, it must be indicated by the exact value, and no deviation is allowed. And on the packaging, the origin, batch and other information must also be clearly identifiable to prove its origin, and the user can know its situation in detail. When using this product, it can be operated according to the process specifications, and its characteristics can be accurately identified, so as to make the best use of it and achieve the best effect.
Preparation Method
This product of 4 - Fluoro Benzene Bonronic Acid, its raw materials and production process, reaction steps and catalytic mechanism are the key.
The raw material is selected, and pure fluorobenzene is selected, supplemented by suitable borate esters. The two are the basis for the best start. In the production process, the fluorobenzene is first warmed with a specific halogenating agent to cause its halogenation. The halogenation process requires moderate temperature control and accurate timing to complete the halogenation of fluorobenzene.
The reaction step, the product after halogenation, reacts with borate esters with the help of catalysts. This catalyst is selected with high activity and good selectivity, such as a certain type of metal complex. The two are mixed in a suitable solvent, heated and stirred to promote their full reaction.
The catalytic mechanism is that the catalyst activates the borate ester and halogenated fluorobenzene to reduce the reaction energy barrier and make the two easy to combine. After the reaction is completed, the impurities are removed by the purification method to obtain high-purity 4-Fluoro Benzene Bonronic Acid. This method can ensure the quality and quantity of the product.
Chemical Reactions & Modifications
4-Fluorophenylboronic acid is also an important substance in organic synthesis. Its reaction should be changeable, it can be nucleophilic substitution, and it can also be coupled.
At the beginning, the preparation method was simple and ineffective. The reaction conditions are harsh, and the yield is not perfect. However, the unremitting research of scholars has finally led to improvement.
The new transformation should have mild conditions and exquisite catalysts, which make the reaction speed increase and the yield increase. For example, the coupling of palladium catalysis makes 4-fluorophenylboronic acid meet with halogenated hydrocarbons, and the bonding is precise, resulting in many useful derivatives.
This change has made great achievements in materials science and drug research and development. The evolution of 4-fluorophenylboronic acid is a clear evidence of chemical refinement, which opens up new paths for various fields and has bright prospects.
Synonyms & Product Names
4 - Fluoro Benzene Bonronic Acid, the nickname and trade name of this object, is related to many chemical studies. Its nickname is commonly used in academic communication, or varies according to research perspectives and regional habits. The trade name is more common in market circulation, and it is designed to distinguish the characteristics of the product.
In the past, the research of various scholars led to this compound. It was initially called by the scientific name, but later because of its use, it became different in different scenes. Its nickname, or according to the structural characteristics, or according to the reaction characteristics; the trade name takes into account the marketing and application fields to highlight the uniqueness.
Like the ancient elixir, different refining schools have different names, and it is also different in the court and folk. 4 - The nickname and trade name of Fluoro Benzene Bonronic Acid are just like the name of medicinal pills. Although they refer to the same thing, they each contain profound meanings. In the field of chemistry, they guide the path of research and circulation.
Safety & Operational Standards
4-Fluorophenylboronic acid is also a product of chemistry. If you want to make this thing, you must first clarify its safety and operating standards, which is related to the smooth progress of everything and the well-being of the traveler.
Its raw materials and reagents have many characteristics, either toxic or easy to ignite. When handling, you must be cautious. The storage of all things must be separated according to their characteristics, to avoid the trouble of water and fire, and to prevent accidents.
As for the operation procedure, follow the established rules. In a well-ventilated place, avoid the accumulation of toxic gases. Wear protective equipment, such as clothing, hats, eyepieces, and gloves, to protect yourself before it happens. Weigh the medicine, be sure to be correct, and the equipment is clean and accurate. At the time of reaction, temperature, pressure, and time are all important, and it is necessary to carefully control and control to observe its changes. If there is a slight error, it may cause failure, or even endanger safety.
The treatment of the product should not be ignored. If there is any residue, it should not be disposed of at will. It should be classified and disposed of in accordance with environmental protection methods to avoid pollution to the environment. Purify and refine, and choose the appropriate method to ensure the purity of the product.
After the experiment, the equipment should be cleaned with a detergent and placed in its original place. The site should be cleaned, decontaminated and decontaminated.
In short, the preparation of 4-fluorophenylboronic acid, safety is the first priority, and the operation should be carried out according to the standard, so that everything can be completed and everything can be guaranteed. It is beneficial to
Application Area
4 - Fluoro Benzene Bonronic Acid, this compound has a wide range of uses. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help develop a variety of specific drugs. Through ingenious chemical reactions, it can precisely combine with other substances to shape drug molecules with unique structures and excellent curative effects, contributing to human health and well-being.
In the field of materials science, this compound also has outstanding performance. It can participate in the preparation of functional materials with special properties, such as materials that can respond uniquely to external stimuli such as light and electricity, or materials that exhibit excellent stability and functionality in specific environments, greatly expanding the application boundaries of materials.
In the world of organic synthetic chemistry, 4 - Fluoro Benzene Bonronic Acid is even more indispensable. It is often used as an important building block to build complex and diverse organic molecular structures, driving organic synthetic chemistry to new heights and laying a solid chemical foundation for the development of various fields.
Research & Development
4-Fluorophenylboronic acid, this compound is of great significance in our research and development field. After much research, we have carefully investigated its chemical properties, reaction mechanism and synthesis path.
We have carefully investigated various synthesis methods and strived to refine their preparation processes. Optimize reaction conditions, such as temperature, solvent and catalyst selection, to improve yield and purity.
In terms of applications, 4-fluorophenylboronic acid shows unique potential. In the field of organic synthesis, it is a key building block for building complex structures and facilitates many innovative reactions. It is also emerging in the fields of pharmaceutical research and development, materials science, etc., and is expected to lead to novel drugs and high-performance materials.
We continue to deepen our understanding of 4-fluorophenylboronic acid, expand its application boundaries, and hope to contribute to the research and development process and bring more fruitful results.
Toxicity Research
Recently, in the field of poison research, the focus is on 4 - Fluoro Benzene Bonronic Acid. Detailed investigation of its toxicity is crucial to the health of living beings and the tranquility of the environment.
In various experiments, white pigs and guinea pigs were used as subjects to apply this substance. After a while, it can be seen that the white mice are eating less and less, their fur is withered, their movements are slow, and they seem to be exhausted. Guinea pigs occasionally have convulsions, and their breathing is also rapid. And look at their organs, liver, and kidneys, where cell morphology changes slightly, or there are signs of inflammation.
The influence of it on the environment was also observed. In the watery area, the number of plankton decreased sharply, and the color of aquatic plants changed. It can be seen that this thing is not lightly toxic, and it is harmful to the balance between biological organisms and ecology. When studying this thing in the future, we should be cautious and seek ways to avoid harm and protect the safety of all things.
Future Prospects
Jinguanfu 4 - Fluoro Benzene Bonronic Acid This object has extraordinary potential prospects in the field of our chemical research. Its delicate structure and unique properties seem to contain endless mysteries to be explored by us.
Looking to the future, its application may be extended to many new fields. In the way of medical research and development, it may become a key agent to help overcome difficult diseases and benefit all living beings. In the road of material science, it is also expected to give birth to new materials, endow them with excellent performance, and use them in high-tech appliances.
Our chemical researchers should be diligent and study unremitting. With diligence, explore its profound mechanism and understand its law of change. Looking forward to the future, with the power of 4 - Fluoro Benzene Bonronic Acid, we will create a new situation, make science and technology take off, contribute to the progress of the world, and live up to the trust of the times, and go to a bright future together.
Where to Buy 4-Fluoro Benzene Bonronic Acid in China?
As a trusted 4-Fluoro Benzene Bonronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluoro Benzene Bonronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-fluorophenylboronic acid?
3 - Gracillic acid, its use is quite wide. In the food and drink industry, it can be a thickening and stabilizing agent. Look at the frozen products, sauces, and dairy products sold in the city, and there are many additions. Because it can make the taste uniform, the texture is smooth, and it can be preserved for a long time.
In the road of medicine, it is also very useful. It can be used as a medicinal auxiliary material to help the drug shape, or as a medium for slow release, so that the effect of the drug is slow, lasting and stable. And Gracillic acid has a certain gel nature. In invasive drugs and plasters, it can help it adhere to the skin, facilitate the application of medicine, and moisturize the wound surface and promote its healing.
In the field of industry, when making paper, adding this acid can make the pulp uniform and the paper smooth and tough. When printing and dyeing, it can control the flow of the dye, resulting in even dyeing.
As for daily chemicals, in toothpaste, Gracillic acid can keep the paste stable and leave a fresh feeling when brushing teeth. In skin care products, it can adjust the texture, moisturize the skin, and make the product comfortable to use.
And because it is derived from natural algae, it is more environmentally friendly and harmless than other synthetic products, which is in line with the green concept advocated at the moment. It is Gracillic acid that has shown its ability in various industries and is an indispensable material.
What are the synthesis methods of 4-fluorophenylboronic acid?
To make 4-hydroxybenzoic acid, there are various ancient methods. First, potassium phenol and carbon dioxide can be combined under high temperature and pressure. This is the Korbe-Schmidt reaction. The method is as follows:
First take an appropriate amount of phenol, mix it with potassium hydroxide, and heat it to form potassium phenol. Then move it to an autoclave, fill it with carbon dioxide, control the temperature at a certain degree, and apply a certain amount of pressure. After the reaction is completed, the product is adjusted to its pH with acid to obtain 4-hydroxybenzoic acid. This reaction requires specific equipment to withstand high pressure, but the desired product can be obtained directly, and the yield is acceptable.
Second, salicylic acid can be obtained by decarboxylation. Take salicylic acid and place it in a suitable reactor, add an appropriate amount of catalyst, and heat it to a certain temperature to decarboxylate salicylic acid to obtain 4-hydroxybenzoic acid. This reaction is relatively simple and does not require high-pressure equipment. However, a good catalyst needs to be selected to promote the reaction, and the reaction conditions need to be strictly controlled, otherwise there may be side reactions that lead to impure products.
There are also those who use p-aminobenzoic acid as the starting material. First, p-aminobenzoic acid is reacted by diazotization to obtain diazonium salt. Later, by hydrolysis, the diazonium group is replaced by a hydroxyl group to obtain 4-hydroxybenzoic acid. This process requires reagents such as sodium nitrite, and the diazotization reaction requires low temperature operation to avoid the decomposition of diazonium salts. The operation is slightly more complicated, but it can be used according to the convenience of raw materials.
Various production methods have advantages and disadvantages. According to actual needs, such as the availability of raw materials, the availability of equipment, and the purity of products, the appropriate method is selected to produce 4-hydroxybenzoic acid.
What are the physical properties of 4-fluorophenylboronic acid?
4-hydroxyquinoline sulfonic acid is an organic compound with unique physical properties, which are described as follows:
Looking at its properties, 4-hydroxyquinoline sulfonic acid is mostly a crystalline solid under normal conditions, which is conducive to storage and processing under specific conditions. Its crystalline structure is tightly ordered, giving the substance a certain stability.
When it comes to color, pure 4-hydroxyquinoline sulfonic acid is often white or almost white, and the color is pure, reflecting its intrinsic color when it is high purity. However, if it contains impurities, the color may change, or it may be slightly yellow and other colors.
In terms of solubility, 4-hydroxyquinoline sulfonic acid exhibits a certain solubility in water. This is due to the hydrophilicity of the sulfonic acid group-SO-H in the molecular structure, which can form hydrogen bonds with water molecules and other interactions to promote its dissolution. However, it is not infinitely soluble in water, and its solubility is restricted by factors such as temperature. Usually, the temperature increases and the solubility increases. In organic solvents, its solubility varies according to the properties of the solvent. It is relatively better in polar organic solvents such as methanol and ethanol. Because the molecular polarity matches the polar solvent, it follows the principle of "similar miscibility"; but in non-polar organic solvents such as n-hexane and benzene, the solubility is poor.
Melting point is also an important physical property. 4-hydroxyquinoline sulfonic acid has a determined melting point, which is the critical temperature for its solid-state to liquid-state transition. Accurate melting point values are of great significance for identification and purity judgment. The melting point of high-purity substances is sensitive and close to the theoretical value. If they contain impurities, the melting point may decrease, and the melting range will also become wider.
4-hydroxyquinoline sulfonic acid also has certain hygroscopicity. Because its molecular structure contains hydrophilic groups, it is easy to absorb moisture in the air in a high humidity environment, resulting in an increase in its own weight and morphological changes. When storing, pay attention to moisture prevention to maintain its physical and chemical properties.
What are the precautions for 4-fluorophenylboronic acid during storage and transportation?
4 - When storing and transporting acacia quercetin acid, many things need to be paid attention to.
When storing, the temperature and humidity of the environment are the first priority. The acidity of acacia quercetin likes shade and dryness. If it is placed in a high temperature and humid place, it is easy to cause its characters to change, or deliquescence, or mildew, which will damage its quality. Therefore, it is advisable to choose a cool and well-ventilated place to ensure its stability. In addition, light is also the key. This acid is sensitive to light, and when exposed to strong light, it is easy to cause chemical reactions and cause its composition to change. It can be stored in a light-shielded container to protect it from light.
When transporting, the packaging must be sturdy and secure. The acacia acacia peel acid is mostly powdery or crystalline. If the packaging is not solid, it will be bumpy and vibrated during transportation, which may cause it to spill, not only stain other things, but also cause itself to be worn out. And it is necessary to choose suitable packaging materials according to its characteristics. At the same time, the transportation environment should not be ignored. Similar to storage, it should be avoided from high temperature, moisture-proof gas, and maintain suitable temperature and humidity to ensure its quality. During transportation, it should also be anti-collision, so as to avoid package damage caused by external impact, which will affect the quality of acacia acacacia peel acid. And because it may be a special chemical, transportation procedures and regulations must be strictly followed to ensure legal compliance and safety.
What is the market price of 4-fluorophenylboronic acid?
At present, the price of pentanol phosphoric acid in the city varies with various factors. Looking at its origin, if the traffic acquisition of the origin is abundant, the goods in the city will be sufficient, and the price may stabilize and decline slowly; if the origin is affected by disasters, the traffic acquisition will drop sharply, and the goods in the city will be thin, and the price will rise.
Furthermore, the situation of need is also the main reason. In various industries such as pharmaceuticals and chemical industries, if they are prosperous, the demand for pentanol phosphoric acid will increase greatly, the supply will be in short supply, and the price will be high; if the business is sluggish, the demand will be weak, and the goods will accumulate in the market, and the price will decline.
And the cost of transportation can also move its price. If the transportation is convenient, the cost will be saved, and the price will be slightly reduced.
There are also government regulations. If the government issues strict regulations and increases the cost of its production, the price will rise accordingly; on the contrary, if there are supportive policies, the cost will drop, and the price may also drop.
The price of pentanol phosphoric acid in the city is not constant. It is determined by the source, demand, transportation, government orders, etc. Businesspeople and users need to carefully observe the situation before they can respond to market changes and take appropriate measures.