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What is the main use of 4-Fluoro-Alfa- (2-Methyl-1-Oxopropyl) -Gamma-Oxo-N, Beta-Diphenyl Benzene Butaneamide
4 - Fluoro - Alfa - (2 - Methyl - 1 - Oxopropyl) - Gamma - Oxo - N, Beta - Diphenyl Benzene Butaneamide, this is an organic compound. Its main use is more common in the field of medicinal chemistry.
Looking at past medical investigations, such organic compounds are often used as lead compounds. Due to their specific chemical structure and activity, they can be used as a starting point in the creation of new drugs. Chemists modify and modify their structures in order to obtain new drugs with better efficacy and less side effects.
For example, in the development of anti-tumor drugs, this compound may interact with specific targets in tumor cells by virtue of its unique structure, or block key signaling pathways, or inhibit the activity of tumor cell proliferation-related proteins, thus providing new ideas and directions for the development of anti-tumor drugs.
In the field of anti-inflammatory drug research, it may also demonstrate anti-inflammatory potential by regulating the release of inflammation-related cytokines and inhibiting the synthesis of inflammatory mediators, laying the foundation for the development of new anti-inflammatory drugs.
In the field of pharmaceutical chemistry, such compounds are like treasures. After in-depth excavation and research, they may bring many benefits to human health and play a key role in disease treatment.
What are the physical properties of 4-Fluoro-Alfa- (2-Methyl-1-Oxopropyl) -Gamma-Oxo-N, Beta-Diphenyl Benzene Butaneamide
4 - Fluoro - Alfa - (2 - Methyl - 1 - Oxopropyl) - Gamma - Oxo - N, Beta - Diphenyl Benzene Butaneamide is an organic compound, and its physical properties are crucial, which is related to many properties and uses of this compound.
The state of this substance, or a solid powder, has a white appearance and fine texture, which is caused by factors such as intermolecular forces and crystal structures. This form is easy to store, transport, and is also conducive to subsequent processing and application.
Melting point is also an important physical property. Its specific melting point is the temperature at which the molecule overcomes the lattice to convert the solid state to the liquid state. This melting point value is determined by the compactness of the molecular structure and the strength of the interaction force. The specific melting point of this compound is of great significance in the separation, purification and identification process. The presence of different impurities or the change of the melting point can be used to judge its purity.
Solubility is also an important physical property. In organic solvents such as ethanol and acetone, or with a certain solubility, but in water solubility or poor. This is due to the ratio and polarity of hydrophilic and hydrophobic groups in the molecule. Its solubility affects the dispersion and mixing of substances in chemical reactions and pharmaceutical preparations, and is also related to the absorption and distribution in organisms.
Density indicates unit volume mass. Its density may be similar to that of similar structural compounds, and is affected by molecular weight and molecular accumulation. Knowing the density is of great significance in the measurement of materials in chemical production and the proportion of reaction systems.
The refractive index is also one of the physical properties. When light passes through this compound, the propagation direction changes, and the refractive index reflects the degree of this change. The refractive index is related to the molecular structure and composition, which is an important basis for the identification and analysis of this compound.
The physical properties of this compound are crucial to its research and application. It is of key significance in the fields of organic synthesis, drug development, and materials science. It helps researchers to deeply understand the characteristics and expand the scope of application.
What are the chemical properties of 4-Fluoro-Alfa- (2-Methyl-1-Oxopropyl) -Gamma-Oxo-N, Beta-Diphenyl Benzene Butaneamide
4 - Fluoro - Alfa - (2 - Methyl - 1 - Oxopropyl) - Gamma - Oxo - N, Beta - Diphenyl Benzene Butaneamide, this is an organic compound. Looking at its structure, it contains fluorine atoms, benzene rings, ketone groups, amide groups and other functional groups, and the interaction of each functional group endows the compound with unique chemical properties.
The introduction of fluorine atoms often enhances the stability and fat solubility of molecules. Because of its high electronegativity, it can change the electron cloud distribution of molecules, making molecules more active. In chemical reactions, it may easily trigger reactions such as nucleophilic substitution and electrophilic addition.
The intra-molecular benzene ring structure has a conjugated system, which endows the molecule with certain rigidity and stability. The electron cloud density of the benzene ring is high, and it is prone to electrophilic substitution reactions, such as halogenation, nitrification, and sulfonation.
Ketone group (-CO -) is a strong electron-absorbing group, which can reduce the electron cloud density of the carbon atoms connected to it. In the reaction, or at the check point of nucleophilic attack, it is prone to addition reactions, such as forming ketals with alcohols and imines with amines.
Amide group (-CONH -) has both certain stability and reactivity. Because the lone pair electrons on the nitrogen atom can form conjugation with the carbonyl group to enhance molecular stability. However, under specific conditions, such as acid-base catalysis, hydrolysis reactions can occur to generate corresponding acids and amines.
Overall, the compound may have potential application value in organic synthesis, pharmaceutical chemistry and other fields due to the characteristics and interactions of various functional groups it contains. It can be used as an intermediate for the synthesis of complex organic molecules, or based on its structural properties to develop drugs with specific biological activities.
What is the production process of 4-Fluoro-Alfa- (2-Methyl-1-Oxopropyl) -Gamma-Oxo-N, Beta-Diphenyl Benzene Butaneamide
Preparation of 4-fluoro - α -( 2-methyl-1-oxopropyl ) - γ - -N, β-diphenylphenylbutylamide, the preparation method is as follows:
First take an appropriate amount of the parent compound of phenylbutylamide, which is the key substrate for the initiation of the reaction. Prepare a clean and dry reaction vessel to ensure that the reaction environment is not disturbed by impurities. In this vessel, accurately measure a certain proportion of the halogenated alkane reagent. The halogenated alkane needs to be a specific structure containing fluorine atoms and should be adapted to the parent structure of phenylbutylamide to facilitate subsequent nucleophilic substitution reactions.
Then, add an appropriate amount of alkali as a catalyst. The choice of this base is very important, which needs to be able to effectively promote the nucleophilic substitution step without causing too many side reactions. When heating the reaction system at a suitable temperature, it is usually necessary to control the temperature within a certain precise range according to the properties of the substrate and the reagent. Generally, the reaction can be started by moderate heating.
When heating, closely observe the reaction process, or use analytical methods such as thin-layer chromatography to monitor the consumption of reaction raw materials and the formation of products. After the nucleophilic substitution reaction reaches the expected level, that is, most of the raw materials are converted into fluorine-containing intermediates, the next step of the reaction is carried out.
Take another reaction device, put in the fluorine-containing intermediate, and then add a specific acylating reagent. This acylating reagent needs to have the ability to react with the intermediate to form a specific acyl structure in the target product. At the same time, an appropriate amount of catalyst is added to accelerate the rate of acylation reaction.
The reaction temperature and reaction time are controlled again. In this process, the control of temperature and time depends on the purity and yield of the product. After the acylation reaction is completed, the reaction mixture is treated by conventional separation and purification methods such as extraction and column chromatography to obtain pure 4-fluoro - α -( 2-methyl-1-oxopropyl ) - γ - oxo-N, β-diphenylphenylbutylamide products. The whole process requires fine operation and strict control of each reaction condition to obtain high-quality products.
4-Fluoro-Alfa- (2-Methyl-1-Oxopropyl) -Gamma-Oxo-N, Beta-Diphenyl Benzene Butaneamide What are the application fields
4-Fluoro-alpha- (2-methyl-1-oxopropyl) -gamma-oxo-N, beta-diphenylphenylbutylamide, this compound may be useful in the fields of medicine and materials.
In the field of medicine, fluorine atoms, benzene rings and specific amide groups in its structure give it unique physical and chemical properties. It may be able to show therapeutic potential by precisely regulating specific biological targets. For example, some fluorine-containing compounds, due to the high electronegativity of fluorine atoms, can enhance the binding force between drugs and targets and improve curative effect. The fluorine atoms in this compound may change the electron cloud distribution of molecules, optimize their interaction with biomacromolecules, or be used to develop innovative drugs for specific diseases such as tumors and nervous system diseases.
In the field of materials, its complex structure can provide a variety of interaction check points. The rigid structure of the benzene ring and the hydrogen bonding ability of the amide group may make the compound a key unit for constructing high-performance materials. Or it can be used to prepare functional materials with special optical and electrical properties, such as in organic optoelectronic materials, using its structural characteristics to regulate the electron transport and luminescence properties of molecules to produce more efficient Light Emitting Diodes or solar cell materials.
Furthermore, in the field of chemical synthesis, it can act as a precursor or intermediate. With its specific functional groups, through a series of organic reactions, more compounds with complex structures and unique functions can be derived, expanding the variety and application range of chemical products.