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4-Fluoro-3-Nitrotrifluoromethylbenzene

4-Fluoro-3-Nitrotrifluoromethylbenzene

Hongda Chemical

    Specifications

    HS Code

    274358

    Chemical Formula C7H3F4NO2
    Molecular Weight 209.097 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 194 - 196 °C
    Density 1.509 g/cm³
    Flash Point 79.4 °C
    Solubility In Water Insoluble
    Refractive Index 1.446

    As an accredited 4-Fluoro-3-Nitrotrifluoromethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - fluoro - 3 - nitrotrifluoromethylbenzene packaged in air - tight glass bottles.
    Storage 4 - fluoro - 3 - nitrotrifluoromethylbenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and direct sunlight. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions. Ensure proper labeling for easy identification and handling.
    Shipping 4 - fluoro - 3 - nitrotrifluoromethylbenzene is shipped in accordance with strict chemical regulations. It's packaged securely in suitable containers, transported by specialized carriers, ensuring compliance with safety and environmental protection requirements.
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    4-Fluoro-3-Nitrotrifluoromethylbenzene 4-Fluoro-3-Nitrotrifluoromethylbenzene
    General Information
    Historical Development
    4 - Fluoro - 3 - Nitrotrifluoromethylbenzene is a chemical substance, and its historical evolution is quite impressive. In the past, chemists explored various compounds and went through countless attempts and studies. At that time, science and technology were not as developed as they are today, and the research road was full of thorns. However, with the wisdom and perseverance of the predecessors, chemists continued to develop in the field of organic chemistry.
    In the process of studying fluorine-containing, nitro and trifluoromethyl compounds, many chemists paid attention to the unique properties of such structures. After repeated experiments, mixing different reactants, exploring different reaction conditions, and gradually clarifying the way to synthesize 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene. From the initial difficult exploration to the gradual maturation of the method, the preparation process has been continuously optimized, laying a solid foundation for the subsequent application of this compound in materials science, drug development and other fields.
    Product Overview
    4 - Fluoro - 3 - Nitrotrifluoromethylbenzene, organic compounds are also. Its shape and color, at room temperature or as a colorless liquid, have a special smell. Looking at its molecular structure, fluorine atoms, nitro groups and trifluoromethyl groups are connected to the benzene ring.
    This compound is widely used in the field of organic synthesis. It is often a key intermediate for the preparation of special materials and pharmaceuticals. With its unique chemical properties, it can lead to a variety of chemical reactions, such as nucleophilic substitution, reduction, etc.
    Synthesis method, or through a specific reaction path, starting from benzene derivatives, with suitable reagents and conditions, gradually build its structure. When preparing, it is necessary to pay attention to the temperature, pressure, catalyst and other factors of the reaction to increase its yield and purity. Therefore, 4-Fluoro-3-Nitrotrifluoromethylbenzene has important value in chemical research and industrial production.
    Physical & Chemical Properties
    4 - Fluoro - 3 - Nitrotrifluoromethylbenzene is an organic compound with unique physical and chemical properties. Looking at its shape, it is mostly a colorless to light yellow liquid at room temperature, with a special odor. Its boiling point is about [X] ° C, and its melting point is about [X] ° C. These two characteristics are of great significance for the control of specific reaction conditions and the separation and purification process.
    In terms of solubility, the compound is insoluble in water, but it can be miscible with many organic solvents, such as ethanol, ether, etc. This characteristic makes it often used as a reaction solvent or intermediate in the field of organic synthesis. Its chemical properties are active, and fluorine atoms, nitro groups and trifluoromethyl molecules give unique reactivity. Nitro has strong electron absorption, which reduces the electron cloud density of benzene ring, which increases the difficulty of electrophilic substitution reaction; while fluorine atoms have strong electronegativity, but can enhance molecular stability and fat solubility. Trifluoromethyl also has strong electron absorption effect, which affects molecular reactivity and physical properties. These properties together determine that 4-Fluoro-3-Nitrotrifluoromethylbenzene is widely used in organic synthesis and materials science.
    Technical Specifications & Labeling
    Today there is a thing called 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene. The technique of making it is related to technical specifications and identification (commodity parameters), and it is our deep research.
    To make this thing, we need to follow the method of precision. The choice of raw materials must be in line with its quality, and the weighing must be accurate, and it must not be wrong at all. When reacting, various variables such as temperature and pressure must be strictly monitored and controlled. If the temperature is high, it may change qualitatively, and if the temperature is low, it may cause a slow reaction. The same is true for pressure, and if it is not appropriate, it will affect the process of its transformation.
    There are also rules for marking this thing. List its name in detail, with the description of its characteristics, such as color, taste, state, etc. In particular, its chemical properties, such as stability and reactivity, should be well understood by the user to avoid the risk of accidents. Commodity parameters should also be detailed, and the proportion of ingredients and the geometry of purity should be clearly marked to prove its quality and make the user believe it. In this way, this product can be used in various applications to show its full potential and live up to expectations.
    Preparation Method
    4 - Fluoro - 3 - Nitrotrifluoromethylbenzene is an important chemical substance. Its preparation requires a delicate method. The selection of raw materials is extremely critical, and the appropriate compounds containing fluorine, nitro and trifluoromethyl are selected.
    The preparation process is as follows: First, a specific fluorine-containing raw material is mixed with a nitrogenation reagent in a precise ratio. Under the action of a suitable temperature and catalyst, the nitro group is introduced into a specific position through nitrification reaction. This step requires strict control of the reaction conditions to ensure the accurate direction of the reaction.
    Then, a reagent containing trifluoromethyl is added, and the trifluoromethyl is successfully connected through a specific reaction step. After each reaction step, it should be properly separated and purified.
    In this process, the design of the reaction device, the control of the reaction time and the suppression of side reactions are all key links. With such rigorous raw material selection, exquisite production process, reasonable reaction steps and effective catalytic mechanism, 4-Fluoro-3-Nitrotrifluoromethylbenzene can be efficiently prepared.
    Chemical Reactions & Modifications
    Since modern times, the art of chemistry has become more and more refined. In 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene this thing, many sages have studied it. Its chemical reaction initially followed the old method, but the effect was not perfect.
    There are wise people who think about change, understand the opportunity, and seek to change the chemical properties. Try to enter it with a new agent, or adjust the temperature and pressure of the reaction, hoping to get good results. At the beginning, there are many obstacles, the rate of reaction has not increased significantly, and the purity of the product is not enough.
    However, everyone was not discouraged, and repeatedly inferred and inspected all ends. In the end, with a certain method, the speed of reaction is greatly increased, and the quality of the product is purer. This is one of the great advances in the improvement of chemical reactions, paving the way for the future research and use of this product, and more wonderful achievements can be expected in the future.
    Synonyms & Product Names
    4 - Fluoro - 3 - Nitrotrifluoromethylbenzene, this substance has various synonymous names and commodity names in the field of chemical industry. Its synonymous name, or according to its chemical structure characteristics, such as according to the arrangement of atoms and groups, there are specific atomic sequence and group relationship.
    As for the name of the product, each record label is taken. Or re-emphasize its characteristics to highlight its high efficiency in a certain type of reaction, or its high purity, suitable for fine synthesis. This substance has unique chemical activity due to the combination of fluorine, nitro and trifluoromethyl in its structure. In the process of organic synthesis, it is a key raw material for the preparation of special materials and pharmaceutical intermediates. The diversity of its synonyms and trade names reflects the wide demand for this material in the chemical industry, and the different emphasis on its characteristics in various application fields, all of which are the signs of promoting chemical technology.
    Safety & Operational Standards
    4 - Fluoro - 3 - Nitrotrifluoromethylbenzene is a common chemical in chemical research. Safety and operating standards are of paramount importance in its production, use and storage, which is related to the safety of researchers and endangers the smooth operation of experiments.
    Researchers must strictly follow safety procedures when handling this chemical. The correct wearing of the first protective equipment, such as wearing suitable protective gloves, must be made of materials that can effectively resist the erosion of the chemical to protect the skin of the hands. At the same time, wear protective glasses to prevent chemicals from splashing into the eyes and causing serious damage to the eyes. Wear protective clothing to ensure full protection of the body.
    The operating environment also has strict requirements. It should be carried out in a well-ventilated space. The best choice is a chemical laboratory with a well-ventilated system, so that harmful gases that may be volatilized can be quickly discharged, reducing the concentration of chemicals in the air, and ensuring the safety of the operator's breathing. During the operation, the action should be steady and careful to avoid chemical leakage due to negligence. Once a leak occurs, do not panic, and should be dealt with immediately according to the established procedures. In the event of a small amount of leakage, quickly cover and collect it with a suitable adsorption material, and place it in a designated container for subsequent safe disposal. If it is a large amount of leakage, in addition to the above measures, the surrounding personnel should be evacuated immediately, the scene should be sealed, and irrelevant personnel should be prevented from approaching. At the same time, it should be quickly reported to the relevant departments and handled
    For storage, 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene should be stored in a cool, dry and ventilated place, away from fire and heat sources. Because of its certain chemical activity, it needs to be placed separately from other chemicals, especially to avoid coexisting with substances that are easy to react with, to prevent accidental chemical reactions from causing safety accidents. At the same time, the storage container must be well sealed to prevent leakage, and clearly labeled, indicating the name, nature and hazards of the chemical and other key information.
    Only by strictly observing safety and operating practices can we ensure that 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene can be used safely and effectively in chemical research, minimize latent risk, and ensure the smooth progress of research work.
    Application Area
    4 - Fluoro - 3 - Nitrotrifluoromethylbenzene is a unique chemical substance with a wide range of application fields. In the field of pharmaceutical research and development, based on this, it can make special drugs and treat many diseases. Because of its unique chemical structure, it can accurately act on lesions, or block the reproduction of pathogens, or regulate human biochemical reactions, and help patients recover.
    In the field of materials science, it also shows extraordinary potential. It can be used to create novel functional materials, such as those with special optical and electrical properties. Materials made from this as raw materials may emerge in optoelectronic devices, improve the efficiency and stability of devices, and contribute to the progress of related industries.
    Furthermore, in the development of agricultural chemicals, 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene is also promising. It may help to develop high-efficiency and low-toxicity pesticides, which can not only eliminate pests and diseases, protect crops and thrive, but also reduce environmental damage and achieve the purpose of sustainable agricultural development.
    Research & Development
    In recent years, in the field of chemistry, I have devoted myself to the study of 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene. Its properties are unique, and it has great potential in the process of chemical synthesis.
    At the beginning, I explored the method of its preparation, but encountered countless obstacles. The choice of raw materials, the precision of the ratio, and the temperature of the reaction all need to be studied in detail. After many tests, one path can be obtained, and it can be stabilized.
    Then, study its application. In pharmaceutical synthesis, it can be used as a key intermediate, with strong drug-helping power and obvious effect. In the field of materials, it can also add its characteristics and increase its quality.
    The road to development is not smooth. Cost control and environmental protection are all difficult problems. I should make unremitting efforts to pursue the goodness of craftsmanship and seek far-reaching development. Hope that in the future, this product can be widely used in the world, for the benefit of everyone, and for the advancement of chemistry.
    Toxicity Research
    Today there is a thing named 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene. I am a chemical researcher, and I dare not ignore the matter of its toxicity research.
    The toxicity of this substance is related to the safety of all living beings and cannot be ignored. I will investigate in detail, with the prudence of ancient methods, observe its response to various things, and observe its changes in the environment. After months of study, I have first obtained clues.
    It may be potentially harmful to biological organisms. After entering the body, it will disrupt the normal order of cells and disturb the rules of metabolism. In the environment, it may also be difficult to eliminate for a long time, and it will weigh on the ecological balance. Although the results are not complete, the warning of toxicity has been vividly remembered. In the future, we should investigate it carefully and make sure to clarify it in detail, so as to protect all living things.
    Future Prospects
    Today there is a thing called 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene. Looking at its characteristics, it is unique and widely used. We take the responsibility of chemical researchers to look forward to its future.
    This thing is in the field of chemical industry, with endless potential. Its properties can lead to various reactions and produce a variety of new products. In the way of medicine, or as the foundation of a wonderful medicine, it can save the patient from suffering; in the way of materials, it can become a strange material, which meets the needs of high-tech.
    In the future, science and technology will be new, and this thing will surely attract more attention. Researchers should use their reasons to explore its micro and expand its use. Make it more refined and apply it in a wider way. I believe, 4 - Fluoro - 3 - Nitrotrifluoromethylbenzene will be the pearl of the future chemical industry, shining in various fields, developing endless splendor, and contributing extraordinary power to the progress of the world.
    Where to Buy 4-Fluoro-3-Nitrotrifluoromethylbenzene in China?
    As a trusted 4-Fluoro-3-Nitrotrifluoromethylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Fluoro-3-Nitrotrifluoromethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-fluoro-3-nitrotrifluoromethylbenzene?
    4-Hydroxy-3-carboxytrimethoxybenzoyl group is an important organic compound group. It has a wide range of uses in the field of medicine and is mostly a key intermediate for drug synthesis. Due to its specific chemical structure and activity, this group can endow drugs with unique pharmacological properties. Taking a new type of anti-tumor drug as an example, by introducing this group, the affinity between the drug and the target of tumor cells can be enhanced, the efficacy of the drug can be improved, and the damage to normal cells can be reduced.
    In the field of materials science, it can be used to prepare polymer materials with special properties. Such as preparing polymers with good biocompatibility and degradability for tissue engineering scaffolds. Because this group can interact with various substances in the body, promote cell adhesion and proliferation, and assist tissue repair and regeneration.
    In the chemical study of natural products, many natural products contain this structural fragment. Through the study of natural products containing this group, not only can its biosynthetic pathway be revealed, but also it can provide inspiration and lead compounds for the development of new drugs and functional materials. For example, the active ingredient containing this group was isolated from a rare plant, and it was found to have significant antioxidant and anti-inflammatory activities, laying the foundation for the research and development of related health products and drugs.
    What are the physical properties of 4-fluoro-3-nitrotrifluoromethylbenzene?
    4-Hydrazine-3-aminotrihydrazinylacetylbenzene is a special chemical substance. Its physical properties are unique and have the following characteristics.
    This substance is mostly solid under normal conditions. Looking at its color, it often appears white or nearly white, just like the first snow in winter, pure and pure. Its texture is delicate, and when viewed under light, it occasionally flickers with a subtle luster, just like a fine silver glow hidden in plain silk.
    When it comes to the melting point, it is about [X] degrees Celsius. When the temperature gradually rises to the melting point, this substance disappears like ice in the warm sun, gradually melts from the solid state to a liquid state, and the melting process is stable without any abrupt phenomenon.
    In terms of solubility, it shows a certain solubility in some polar solvents, such as water and ethanol. In water, although it is not completely dissolved, it can be partially dispersed, making the water slightly turbid, just like injecting silk yarn into a clear stream. In ethanol, the dissolution is slightly better, and a uniform mixed system can be formed, just like water and milk blend, regardless of each other.
    Its density is about [X] grams per cubic centimeter, which is slightly higher than that of common water. When held in the hand, it feels solid to the touch and seems to contain endless mysteries between square inches.
    Furthermore, the stability of this substance also has characteristics. Under the environment of normal temperature and pressure without the influence of special chemical reagents, it can maintain its own structure for a long time, and it is not prone to spontaneous decomposition or other chemical changes. It is like a calm old man, who is unperturbed and self-contained. In case of extreme conditions such as high temperature and strong oxidants, its stability is like thin ice in case of fire, rapidly disintegrating, triggering chemical reactions and releasing energy.
    To sum up, the physical properties of 4-hydrazine-3-aminotrihydrazinylacetylbenzene, whether it is appearance, melting point, solubility or density and stability, are unique. They are of great significance in the research and application of chemistry, like a unique key, or a door to unknown chemical mysteries.
    What are the chemical properties of 4-fluoro-3-nitrotrifluoromethylbenzene?
    4-Hydroxy-3-carboxyl trimethoxy anisole, this is an organic compound. It is mild and stable at room temperature and pressure.
    It is acidic to a certain extent. Due to the carboxyl group, the carboxyl group can dissociate hydrogen ions, which can neutralize with bases to generate corresponding salts and water.
    The solubility of this compound is also a key property. In polar solvents, such as water, carboxyl and hydroxyl groups can form hydrogen bonds with water molecules, so it has a certain solubility; however, in non-polar solvents, the solubility is relatively low.
    From the perspective of chemical activity, both hydroxyl and carboxyl groups are active functional groups. Hydroxyl groups can undergo substitution reactions, such as reacting with halogenated hydrocarbons to form ethers; they can also participate in esterification reactions and react with acids to form esters. In addition to neutralization reactions, carboxyl groups can also undergo esterification reactions, and ester compounds are formed with alcohols under the action of catalysts. In addition, although the methoxy group on the benzene ring is relatively stable, it can also participate in some electrophilic substitution reactions under specific conditions. Because it is a power supply group, it can increase the electron cloud density of the benzene ring and make it easier to react with electrophilic reagents.
    Its chemical properties make it widely used in the field of organic synthesis. It can be used as an intermediate for the synthesis of more complex organic compounds, and has potential application value in many fields such as medicinal chemistry and materials science.
    What are the synthesis methods of 4-fluoro-3-nitrotrifluoromethylbenzene?
    To prepare 4-hydroxy-3-aminotrifluoromethylbenzene, the following methods can be used:
    First, an aromatic compound containing a suitable substituent is used as the starting material. First, a halogen atom is introduced into the aromatic ring, such as halogenation of the benzene ring by an electrophilic substitution reaction to obtain a halogenated aromatic hydrocarbon. Then, through a nucleophilic substitution reaction, the halogen atom is replaced by an amino group, and an amino group is introduced. Then, by introducing trifluoromethyl under specific reaction conditions, a trifluoromethyl-containing reagent, such as a trifluoromethylation reagent, can be used to make the trifluoromethyl group connected to a specific position in the arom Finally, through the hydroxylation reaction, the hydroxyl group is introduced at the designated position, and suitable oxidizing agents or other hydroxylating reagents can be selected to achieve the synthesis of 4-hydroxy-3-aminotrifluoromethylbenzene.
    Second, starting from compounds with similar structures, through functional group conversion. For example, if the starting compound contains functional groups that can be converted into amino groups, hydroxy groups and trifluoromethyl groups, the conversion can be carried out in sequence. First convert a functional group into amino groups, then treat another functional group into trifluoromethyl groups, and finally convert the remaining functional groups into hydroxyl groups. This process requires precise control of the reaction conditions and reagent selection to ensure the smooth progress of each step of the reaction and good selectivity, avoid unnecessary side reactions, and successfully prepare the target product.
    Third, a multi-step tandem reaction strategy is used. A series of reactions are carefully designed, so that the starting materials can undergo continuous reactions in the same reaction system, and the target molecular structure is gradually constructed. This strategy requires in-depth understanding of the reaction mechanism and the properties of intermediate products, optimization of reaction conditions, efficient connection of each step of the reaction, and improvement of the total yield and selectivity of the reaction. Finally, the synthesis of 4-hydroxy-3-aminotrifluoromethylbenzene is achieved.
    What are the precautions for storing and transporting 4-fluoro-3-nitrotrifluoromethylbenzene?
    4-Hydroxy-3-carboxytrihydroxymethyl benzyl alcohol is an important compound. During storage and transportation, many matters must be paid attention to.
    The first one is related to storage. This compound is quite sensitive to environmental conditions. It should be stored in a cool, dry and well-ventilated place. Because the temperature is too high, it is easy to cause chemical reactions and damage its chemical properties. If it is in a high temperature environment, or it may cause changes in molecular structure, its activity will be reduced, or even its original efficacy will be lost. And humid environment is also not suitable. Moisture can promote reactions such as hydrolysis and cause it to deteriorate. Therefore, the humidity of the storage place must be strictly controlled. And it should be stored separately from oxidants, acids, bases and other substances. Due to the chemical properties of this compound, it is easy to react with the above substances. If it is mixed, it may lead to safety accidents and make the compound ineffective.
    Second, when transporting. Ensure that the packaging is intact. Strong packaging can prevent leakage due to bumps and collisions during transportation. If the compound leaks, it will not only waste resources, but also cause pollution to the transportation environment, and even endanger the safety of transporters. During transportation, appropriate temperature and humidity conditions should also be maintained. Professional transportation equipment, such as refrigerated trucks, can be used to ensure its chemical stability. At the same time, transporters should also have relevant professional knowledge and be familiar with the characteristics of this compound. In case of emergency, they can deal with it quickly and correctly. Only in this way can we ensure that 4-hydroxy-3-carboxytrihydroxymethylbenzyl alcohol maintains its good chemical properties and quality during storage and transportation, and achieves the purpose of safety and stability.