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4-Fluoro-3-Nitrobenzenesulfonamide

4-Fluoro-3-Nitrobenzenesulfonamide

Hongda Chemical

Specifications

HS Code

953392

Chemical Formula C6H5FN2O4S
Molecular Weight 222.17
Appearance Typically a solid
Melting Point Data may vary, check specific sources
Boiling Point Data may vary, check specific sources
Solubility In Water Limited solubility likely
Solubility In Organic Solvents Soluble in some organic solvents
Odor No distinct common odor reported
Density Data may vary, check specific sources
Flash Point Data may vary, check specific sources
Purity Depends on manufacturing quality
Stability Stable under normal conditions

As an accredited 4-Fluoro-3-Nitrobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - fluoro - 3 - nitrobenzenesulfonamide packaged in a sealed plastic bag.
Storage 4 - fluoro - 3 - nitrobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and contamination. Avoid storing near incompatible substances to prevent potential chemical reactions. Label the storage container clearly for easy identification.
Shipping 4 - fluoro - 3 - nitrobenzenesulfonamide is shipped in sealed, corrosion - resistant containers. Compliance with chemical transport regulations is ensured. It's transported under controlled conditions to prevent degradation and ensure safety during transit.
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4-Fluoro-3-Nitrobenzenesulfonamide 4-Fluoro-3-Nitrobenzenesulfonamide
General Information
Historical Development
4 - Fluoro - 3 - Nitrobenzenesulfonamide, it is also a chemical thing. Its beginning is the work of chemists. At the beginning, it was difficult to explore its nature and the method of making it. At that time, the instrument was not refined, the knowledge was not complete, and it was not easy to understand its details.
However, the determination of chemists, unremitting exploration. Over time, the method of synthesis has gradually improved. From the crude at the beginning to the delicate in the future, every step is the blood of everyone.
With the passage of time, I have a deep understanding of it. Its use in medicine, materials and other fields is gradually emerging. Potential unknown in the past is now being discovered one by one. Looking at its development path, it is like walking on a rugged path until it finally opens up. In the future, it will also develop its extraordinary capabilities in more fields.
Product Overview
4-Fluoro-3-Nitrobenzenesulfonamide, it is also a new substance of chemistry. Its properties are special, with fluorine, nitro and sulfonamide groups. The introduction of fluorine atoms makes this physical property different, increasing its anti-activity and particularity. The presence of nitro groups gives it a certain activity, and it can be reversed like a sulfonamide. Sulfonamide groups are also extraordinary, and can be used to chemize multiple substances, or to form new substances, or to improve physical properties.
The use of this substance is not good, and it can be used in research, or it can be used to solve diseases. In the field of materials, it can be used at the beginning of new materials to explore new ways of use. However, the research is not careful, because of its activity, the reaction should be carefully controlled, and it can be obtained. And good products. Therefore, 4-Fluoro-3-Nitrobenzenesulfonamide limited possibility, waiting for our researchers to explore in depth in order to develop its great use.
Physical & Chemical Properties
4 - Fluoro - 3 - Nitrobenzenesulfonamide is a unique chemical substance. Its physical properties are unique. Looking at its shape, it is often white crystalline, delicate and regular. Its melting point is quite high, and this characteristic makes it melt and transform under specific temperature conditions, showing good thermal stability.
In terms of chemical properties, the presence of fluorine atoms and nitro groups in this substance gives it active reactivity. The electronegativity of fluorine atoms is strong, and the nitro group has an electron-absorbing effect. The two cooperate to change the electron cloud density of the benzene ring. Therefore, it is easy to react with nucleophiles, and can be used as a key intermediate in the field of organic synthesis to participate in the construction of complex organic molecular structures, exhibiting important chemical value. It has significant uses in many chemical research and industrial production processes.
Technical Specifications & Labeling
There are chemical things today, named 4 - Fluoro - 3 - Nitrobenzenesulfonamide. To clarify its technical specifications and labels (commodity parameters), it should be carefully studied.
Its quality must be pure, and impurities should not be stored. Looking at its color, it should be clean and free of impurities, in the shape of plain white. If there are variegated colors, it is not a good product. If you smell it, it should have no peculiar smell. If there is a strange smell such as pungent, it cannot be used.
Its shape should be uniform, the particles are uniform, and there is no agglomeration or uneven powder. Measuring its physical properties such as melting point and boiling point must comply with established regulations. And in different environments, its properties should be stable and not disturbed by changes such as temperature and humidity.
If the label is marked, its name should be clearly stated, and the chemical name and the general name should be noted. The ingredients and content should be listed in detail, and there should be no mistakes. Indicate the usage, dosage, and storage method to prevent its qualitative change. In this way, the technical specifications and labels are detailed, which can ensure the quality and use of this product.
Preparation Method
There is now a method for making 4 - Fluoro - 3 - Nitrobenzenesulfonamide, which is described in detail below. The raw materials are selected, when fluorobenzene, fuming nitric acid and concentrated sulfuric acid are used as the basis. The preparation method is as follows: Take fluorobenzene first, place it in a reaction kettle, slowly enter the mixture of fuming nitric acid and concentrated sulfuric acid, and control the temperature at about fifty to sixty degrees. This is the beginning of the reaction. After some time, the reaction is gradually completed. Subsequent treatment, the reaction solution is poured into ice water, precipitated, filtered, and obtained as a crude product. It is then recrystallized with ethanol and purified. This product is of good purity. Its reaction mechanism is the benzene ring of fluorobenzene. Under the action of nitric acid and sulfuric acid, nitro and sulfonamide groups are introduced in turn to form 4-Fluoro-3-Nitrobenzenesulfonamide. The whole preparation, the raw materials and the process are in line, the reaction steps are orderly, and the purification mechanism is appropriate, and excellent products can be obtained.
Chemical Reactions & Modifications
There are chemical substances today, named 4 - Fluoro - 3 - Nitrobenzenesulfonamide. In the field of chemical research, its reaction and modification are crucial.
Looking at the reaction of this substance, many factors are affected. The change in temperature is like the change of yin and yang. If the temperature is high, the reaction will be more urgent, and if the temperature is low, the rate will be slower. If the ratio of the reactant is like weighing the two ends, the reaction will be different if it is unbalanced.
As for modification, it is designed to make its performance better. Or add other substances to make it more unique, just like good medicine, precise compatibility. In this way, it can be made to play a better role in specific situations. This is the diligent pursuit of chemical researchers, hoping to be able to understand its rationale and make good use of it, so as to promote the progress of chemistry and be used by the world.
Synonyms & Product Names
4 - Fluoro - 3 - Nitrobenzenesulfonamide this thing, its synonymous name, is also the focus of research. Looking at the past, in the field of chemistry, there are many images of each thing. 4 - Fluoro - 3 - Nitrobenzenesulfonamide, or those who call it another name, this synonymous name is essential in academic exchanges and literature records.
Because there are many chemical substances, accurate appellation is essential. Its synonymous name may depend on its characteristics, structure, and discovery process. Knowing its synonymous name is beneficial to the study of the nature, use, and synthesis path of this thing. When chemists discuss 4-Fluoro-3-Nitrobenzenesulfonamide, it is necessary to clarify its synonymous name, so that it can be unimpeded in ancient and modern literature and will not be misunderstood due to different terms. Therefore, the detailed study of the synonymous names and trade names of 4-Fluoro-3-Nitrobenzenesulfonamide is an indispensable part of chemical research, which can make the research more thorough and accurate.
Safety & Operational Standards
4 - Fluoro - 3 - Nitrobenzenesulfonamide Safety and Operation Specifications
F 4 - Fluoro - 3 - Nitrobenzenesulfonamide, is an important substance in chemical research. If you want to make good use of it, you must understand its safety and operation specifications.
First words storage. When placed in a cool, dry and well ventilated place. Do not co-store with oxidizing agents, reducing agents, etc. to prevent unexpected chemical reactions. And the storage place should be away from fire and heat sources to ensure safety.
As for the operation, the experimenter must wear suitable protective clothing, protective gloves and goggles. Operating in a fume hood is the key. Because the substance may be irritating, if exposed to the air, it is easy to cause damage to the human respiratory tract, skin, etc. When operating, the action should be steady and slow to avoid the leakage of substances. If it is accidentally scattered, clean it up immediately. Cover with inert material first, then collect it carefully and dispose of it according to regulations.
If you come into contact with this substance, you must not know the emergency method. If it comes into contact with the skin, rinse it with plenty of water immediately, then wash it with soap. If it enters the eye, rinse it with flowing water or normal saline immediately and seek medical attention in time. If you inhale it accidentally, move it to a place with fresh air to keep the respiratory tract unobstructed. If necessary, perform artificial respiration and rush to medical treatment.
Furthermore, after the experiment is completed, the utensils used must be properly cleaned. Discarded 4 - Fluoro - 3 - Nitrobenzenesulfonamide and related waste should be disposed of in accordance with chemical waste treatment regulations and should not be discarded at will to avoid polluting the environment.
In short, in the research and use of 4 - Fluoro - 3 - Nitrobenzenesulfonamide, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, protect the health of personnel, and maintain the cleanliness of the environment.
Application Area
4 - Fluoro - 3 - Nitrobenzenesulfonamide is a unique chemical substance. Its application field is wide, and it can be used as a key intermediate in the field of pharmaceutical research and development. For example, in the production of antibacterial drugs, it can accurately target the key metabolic links of bacteria to achieve the effect of bacteriostatic and sterilization. In the field of materials science, the special materials it participates in the synthesis have unique electrical and optical properties, or can be used to manufacture advanced electronic components. Furthermore, in agricultural chemistry, pesticides made from this basis can effectively resist pests and diseases, and have little harm to the environment. Due to its unique chemical structure, this substance shows excellent application potential in many fields, providing a solid foundation for the development of related technologies, just like a shining star, guiding the direction of scientific research and promoting the development of various fields to a higher level.
Research & Development
The rise of modern chemistry, the study of substances, is changing with each passing day. I focus on 4 - Fluoro - 3 - Nitrobenzenesulfonamide this material, and devote myself to exploring.
At the beginning, I observed its structure, which seems to contain mystery, fluorine, nitro and sulfonamide groups coexist, interact with each other, or hide different activities. It is the method of synthesis that has been exhaustively studied. After many attempts, I have reconciled various reagents, controlled temperature and speed, and unremitting search.
Synthesis has been obtained, test its properties. Observe its dissolution in different solvents and measure its reactivity. Found in alkaline environments, the reaction is quite fast, and it seems to have a unique mechanism.
If this research can be refined, it may be useful in the fields of medicine and materials. Can be used as a lead compound to develop new drugs; in materials, or can give it specific properties. I am determined to delve deeper into it, hoping to make breakthroughs, promote the development of this substance, and do my best for the progress of chemistry.
Toxicity Research
The taste of the nature of things, related to human use, must be observed. Now in 4 - Fluoro - 3 - Nitrobenzenesulfonamide this substance, the study of its toxicity is particularly important.
When studying its toxicity, it is necessary to examine its chemical structure and explore its response to other substances. Look at its molecular state, fluorine, nitro and other groups, or have extraordinary properties. Fluorine, the activity is quite high, and the nitro group also has the ability to oxidize. The two are in the framework of benzenesulfonamide, which may lead to toxic changes.
Test it with various methods, try it in the body, and observe its impact on the viscera and meridians. Or see its ability to damage the liver and spleen, the follow of qi and blood. And in the environment, it also detects its long-term effect to prevent it from accumulating in water and soil, harming all spirits.
Therefore, the study of toxicity must be thorough and prudent, and the harm must be clarified. Only then can this thing be used well to avoid disasters and keep people healthy.
Future Prospects
Guanfu 4 - Fluoro - 3 - Nitrobenzenesulfonamide, although it is not widely used at present, its future prospects are limitless. This compound has a unique structure, and its fluorine atom interacts with nitro and sulfonamide groups, giving it a variety of chemical activities.
In the field of pharmaceutical research and development, it may be possible to use its characteristics to make new drugs to treat various diseases and save patients from pain. In materials science, it is also expected to use its chemical activity to create novel functional materials for use in electronics, optics and other fields, creating new applications.
Despite the current constraints of technology and cost considerations, over time, with the advancement of science and technology, all kinds of problems will be overcome. At that time, 4-Fluoro-3-Nitrobenzenesulfonamide will be able to shine and contribute to the future scientific development and social progress, so as to develop an infinite future vision.
Where to Buy 4-Fluoro-3-Nitrobenzenesulfonamide in China?
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Frequently Asked Questions

As a leading 4-Fluoro-3-Nitrobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 4-Fluoro-3-Nitrobenzenesulfonamide?
4-Fluoro-3-nitrobenzenesulfonamide, this is an organic compound. Its unique chemical properties allow me to elaborate.
First of all, its structure, above the benzene ring, the fluorine atom and the nitro group live in a specific position, and there are sulfonamide groups connected. This structure creates its unique chemical activity.
In terms of reactivity, although fluorine atoms have strong electronegativity, which reduces the electron cloud density of the benzene ring, due to the strong electron-absorbing effect of the ortho-nitro group, the electron cloud distribution of the benzene ring is more uneven. In this case, the electrophilic substitution reactivity on the benzene ring is greatly changed. The electrophilic substitution of aromatic rings, such as halogenation, nitrification, sulfonation, etc., is affected by fluorine and nitro, and the reaction check point is very different from that of conventional benzene derivatives.
Nitro is a strong electron-absorbing group, which not only affects the reactivity of benzene ring, but also makes the molecule have oxidative properties. Nitro can be reduced to amino groups under specific conditions, which is a commonly used conversion reaction in organic synthesis. The sulfonamide group has a certain acidity, because the hydrogen on the nitrogen atom can leave under the action of appropriate bases to form corresponding salts.
In addition, 4-fluoro-3-nitrobenzenesulfonamide can participate in many condensation reactions. The nitrogen atom of sulfonamide can react with compounds containing active carbonyl groups to form new carbon-nitrogen bonds. This reaction is widely used in the fields of drug synthesis and materials science.
In addition, its solubility also has characteristics. Because the molecule has both polar groups (sulfonamide) and non-polar benzene rings, it has a certain solubility in polar organic solvents such as ethanol and acetone; in non-polar solvents such as n-hexane, the solubility is very small.
The chemical properties of this compound are complex and diverse, and it has important research and application value in organic synthesis, drug development and other fields.
What are the main uses of 4-Fluoro-3-Nitrobenzenesulfonamide?
4-Fluoro-3-nitrobenzenesulfonamide is one of the organic compounds. It has a wide range of uses and shows important functions in many fields.
First, in the field of medicine, it is often used as a key intermediate. When doctors make antibacterial, anti-inflammatory and other drugs, they often rely on this compound to build a specific molecular structure. Taking a new type of antibacterial drug as an example, in its synthesis path, 4-fluoro-3-nitrobenzenesulfonamide can be converted into an ingredient with antibacterial activity through a series of delicate chemical reactions, which can interfere with the specific metabolic process of bacteria to achieve antibacterial effect.
Second, in the field of pesticides, it is also important. In order to develop high-efficiency and low-toxicity pesticides, chemists often use them as starting materials. After ingenious chemical modification, pesticide products that are highly destructive to pests but environmentally friendly can be prepared. This compound can precisely act on specific physiological targets of pests, causing physiological disorders of pests, thus effectively preventing and controlling crop diseases and insect pests and ensuring agricultural harvests.
Third, in the field of materials science, 4-fluoro-3-nitrobenzenesulfonamide is also used. For example, when developing special polymer materials, it can be introduced into polymer structures to improve material properties. Or increase the heat resistance of materials, or strengthen their mechanical properties, so that materials can be used in high-end fields such as aerospace and electronics.
Fourth, in the field of chemical research, it is an important reagent. Chemists use its unique chemical structure to explore new chemical reaction mechanisms and synthesis methods. Taking new catalytic reactions as an example, it can be used to participate in reactions, study the laws of catalyst activity and reaction selectivity, and contribute to the development of organic synthetic chemistry.
To sum up, 4-fluoro-3-nitrobenzenesulfonamide plays a significant role in medicine, pesticides, materials science and chemical research, and has made great contributions to the development of various fields.
What is 4-Fluoro-3-Nitrobenzenesulfonamide synthesis method?
The synthesis of 4-fluoro-3-nitrobenzenesulfonamide is an important topic in the field of chemical synthesis. To synthesize this substance, a common method is to use a compound containing a benzene ring as the starting material.
Take benzene as the initial substrate first, and introduce fluorine atoms and nitro groups by means of an electrophilic substitution reaction. In the electrophilic substitution reaction, a suitable halogenated reagent, such as fluorine gas or a specific fluorine-containing reagent, can be selected. Under appropriate reaction conditions, a fluorination reaction occurs at a specific position on the benzene ring. This process requires fine regulation of reaction temperature, pressure and catalyst to ensure accurate positioning of fluorine atoms.
Then, introduce nitro groups. Mixed acid (a mixture of nitric acid and sulfuric acid) is often used as a nitrifying agent to introduce nitro groups at specific positions on the benzene ring. This step also requires precise control of the reaction conditions to prevent side reactions such as excessive nitrification. At this point, a benzene derivative containing fluorine and nitro groups is obtained.
Subsequently, this derivative is further converted to benzene sulfonamide. Generally, the sulfonation reaction is carried out first, with concentrated sulfuric acid or fuming sulfuric acid as the sulfonating agent, and at a suitable temperature, the sulfonic acid group is introduced on the benzene ring. After that, the sulfonic acid group is converted into sulfonyl chloride. Sulfonyl chloride can be obtained by reacting with sulfonic acid with reagents such as sulfoxide chloride
Finally, the sulfonyl chloride is reacted with ammonia or amine compounds, and 4-fluoro-3-nitrobenzenesulfonamide can be obtained by ammonolysis reaction. This reaction condition is relatively mild, and the yield is considerable. During the whole synthesis process, each step of the reaction needs to strictly control the reaction conditions and carefully purify the intermediate product, so that 4-fluoro-3-nitrobenzenesulfonamide can be effectively and with high purity.
4-Fluoro-3-Nitrobenzenesulfonamide What are the precautions during storage and transportation?
4-Fluoro-3-nitrobenzenesulfonamide is an organic compound. During storage and transportation, many matters need to be paid attention to.
When storing, the first environment should be selected. It should be placed in a cool place, which is easy to change its chemical properties due to high temperature. The temperature should be controlled within a specific range to prevent decomposition or deterioration. And it must be dry, because it may be hygroscopic, the humid environment will make it hygroscopic and affect the quality. Furthermore, it should be placed in a well-ventilated place to avoid the accumulation of harmful gases and cause safety hazards.
This compound may be toxic and corrosive, so the storage place must be kept away from fire and heat sources. Because it may be flammable, there is a risk of combustion and explosion in case of open flames and hot topics. It should also be stored separately from oxidizing agents, reducing agents, etc. to prevent mutual reaction.
During transportation, the packaging should be solid. Make sure that the packaging material can withstand vibration and collision during transportation without leakage. And the packaging should comply with relevant laws and regulations, clearly marked with warning signs to indicate its danger.
Transportation tools are also exquisite, and need to be clean, dry, and free of other substances that may react with them. During transportation, avoid sun and rain, drive according to the specified route, and do not stop in densely populated areas or important places.
In short, when storing and transporting 4-fluoro-3-nitrobenzenesulfonamide, it is necessary to strictly abide by relevant regulations, operate cautiously, and ensure the safety of personnel and the environment from harm.
What is the market price range for 4-Fluoro-3-Nitrobenzenesulfonamide?
What you are inquiring about is the market price range of 4-fluoro-3-nitrobenzenesulfonamide. However, the price of this chemical cannot be generalized, and it varies due to many factors.
First, the state of market supply and demand is the main reason. If the demand for this product is strong and the supply is limited, the price will increase; conversely, if the supply is abundant, the demand will be weak, and the price will fluctuate. Second, the cost of production also affects the price. The price of raw materials, the simplicity of the production process, and the amount of energy consumption are all related to the cost. If raw materials are scarce and expensive, or the cost is high due to the complexity of the production process, the price will also rise.
Furthermore, the quality grade is also related to the price. For high purity and high quality, the price is often higher than that of ordinary grades. In addition, regional differences also have an impact. Different places have different prices due to different transportation costs and market competition. In places with developed economies and fierce competition, or low prices due to competition; in remote areas, inconvenient logistics, or high prices due to increased transportation costs.
In summary, the market price range of 4-fluoro-3-nitrobenzenesulfonamide is difficult to specify, ranging from tens of yuan per kilogram to hundreds of yuan. It depends on the above factors. If you want to know the exact price, you should carefully check the market dynamics and relevant supplier quotations.