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4-Fluoro-3-Methoxynitrobenzene

4-Fluoro-3-Methoxynitrobenzene

Hongda Chemical

Specifications

HS Code

179444

Chemical Formula C7H6FNO3
Molar Mass 171.126 g/mol
Appearance Solid
Melting Point 45 - 47°C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane

As an accredited 4-Fluoro-3-Methoxynitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - fluoro - 3 - methoxynitrobenzene packaged in a sealed plastic bottle.
Storage 4 - fluoro - 3 - methoxynitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and strong oxidizing agents. Store it in a tightly sealed container to prevent vapor leakage. This organic compound, with potential reactivity, requires proper storage to maintain its stability and ensure safety.
Shipping 4 - fluoro - 3 - methoxynitrobenzene is shipped in well - sealed containers. It's handled with care to prevent spills as it's a chemical. Shipment follows strict safety regulations for hazardous substances during transport.
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4-Fluoro-3-Methoxynitrobenzene 4-Fluoro-3-Methoxynitrobenzene
General Information
Historical Development
4 - Fluoro - 3 - Methoxynitrobenzene, the product of chemistry. In the past, it was first studied by various sages. At that time, science and technology were not as prosperous as they are today, and research was difficult.
At the beginning, all scholars observed its related characteristics and explored its properties in a simple way. As the years passed, science and technology gradually flourished, and the research method was also good. Everyone was thinking hard about the reaction and the increase in productivity.
Or in the experimental room, operate day and night, observe its changes, and remember its data. From ignorance to clarity, from crude to subtle. After several generations of research, the method of preparation has become more refined, and the field of application has become wider. From the beginning, it was only an academic study, and later it was used in various industries. This is the development path of 4-Fluoro-3-Methoxynitrobenzene, and it is also one of the spots in chemical evolution.
Product Overview
4-Fluoro-3-methoxynitrobenzene is also an organic compound. Its color may be light yellow, like a crystalline body, with a special taste. The melting and boiling points of this substance have their own values. It melts at a certain temperature and boils at a specific degree.
In the field of chemical industry, 4-fluoro-3-methoxynitrobenzene has a wide range of uses. It is often used as a raw material for the synthesis of a variety of fine chemicals. It is indispensable in the preparation of medicines, pesticides, etc. With its unique structure, it can participate in a variety of chemical reactions. After ingenious steps, various desired products can be obtained.
However, the preparation of this substance requires following the rules. The reaction conditions must be precisely controlled. Temperature, pressure, and the proportion of reactants are all related to success or failure and quality. And because of its certain danger, safety protection cannot be slack during operation to ensure the safety of personnel and the environment.
Physical & Chemical Properties
4 - Fluoro - 3 - Methoxynitrobenzene is an organic compound with unique physical and chemical properties. Looking at its properties, it is mostly solid at room temperature and has a specific crystalline form, which is due to intermolecular forces. Its melting point value is of great significance for identification and purification. After precise determination, its melting point range can be known, which is convenient to control the reaction conditions.
When it comes to solubility, the compound exhibits certain solubility in specific organic solvents such as ethanol and ether, which is closely related to the interaction between solvents and solute molecules, such as van der Waals force, hydrogen bond, etc. In terms of chemical properties, it has unique chemical activity due to the presence of functional groups such as fluorine, methoxy group and nitro group. Nitro groups have strong electron absorption, which decreases the density of benzene ring electron clouds and affects the activity of electrophilic substitution reactions; fluorine atoms have high electronegativity, which can change molecular polarity and affect reaction selectivity; methoxy groups also affect the distribution of benzene ring electron clouds. Many factors work together to determine their performance in various chemical reactions.
Technical Specifications & Labeling
The technical specifications and identification (product parameters) of 4-fluoro-3-methoxynitrobenzene are related to the production and identification of this product. Its characteristics need to be clear, the color is pure and the quality is correct, and there is no variegated color abnormality. The melting and boiling point should be accurately determined to comply with accurate regulations. This is the key to its quality. Purity is also critical, and it must reach a high standard. The impurity content must be strictly controlled at the micro-end. On the label, the product name is clearly marked, the chemical formula is accurately listed, and the molecular weight is clearly marked. Inside and outside the package, warning signs are indispensable to prevent harm. These are all essential to ensure product quality and safety. Only by following this can we get good products and use them in chemical industry to ensure safety.
Preparation Method
4 - Fluoro - 3 - Methoxynitrobenzene is made in this product. When the raw material and production process, reaction steps and catalytic mechanism are carefully considered. The selection of raw materials needs to be pure and suitable, which is related to the quality of the product. The production process follows fine rules, and every step is carefully controlled.
At the beginning of the reaction step, [starting material 1] and [starting material 2] are mixed in a specific ratio at a specific temperature and pressure, and are mixed into the reaction kettle. The catalytic mechanism is promoted by [catalyst name] to increase the rate of reaction and reduce the energy of activation. When the reaction is gradual, its changes are closely monitored, and the temperature and control are closely controlled, until the reaction is almost complete.
Then, after separation and purification, the impurities are removed and purified. Separation is done by [separation method, such as distillation, extraction, etc.], and the appropriate method is selected for purification, such as recrystallization. After these steps, pure 4-Fluoro-3-Methoxynitrobenzene can be obtained for all needs.
Chemical Reactions & Modifications
F 4 - Fluoro - 3 - Methoxynitrobenzene is also an organic compound. Its chemical reaction and modification are of great importance to the academic community.
To obtain this compound, it is often prepared from specific raw materials through various reaction paths. In the reaction, the most important conditions, such as temperature, solvent, catalyst, etc., can affect the rate of reaction and the purity of the product.
As for modification, its functional groups can be modified to expand its use. or introduce new groups to change its physical and chemical properties, making it suitable for medicine, materials and other fields. This compound, through ingenious chemical manipulation, may be able to develop its unique capabilities in the research and development of new materials and the creation of special drugs, etc., contributing to the advancement of science and technology.
Synonyms & Product Names
Today there is a thing called 4 - Fluoro - 3 - Methoxynitrobenzene. This thing has a wide range of uses in the field of chemistry. Its different names are also many, and they are all well known in the industry.
The chemical things have many names, and the same things have different names. Because of the different research angles, or according to their properties, or according to their production methods, many names have been generated. 4 - Fluoro - 3 - Methoxynitrobenzene, its alias is also designed to facilitate academic communication and production practicality.
The industry of Guanfu Chemical Industry, various products, have different names, but their essence is the same thing. The alias of this compound is like a logo, which helps practitioners to accurately identify and use it correctly in the complex chemical world. Although the names are different, their physical properties and chemical properties are constant and do not change depending on the name.
Safety & Operational Standards
4 - Fluoro - 3 - Methoxynitrobenzene is an important substance in chemical research. The safety and operation of 4 - Fluoro - 3 - Methoxynitrobenzene are related to the success of the research and the safety of the researcher, which cannot be ignored.
In the method of storage, this substance should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent the danger of accidents. Because it has certain chemical activity, if the storage environment is improper, it may deteriorate or even cause danger.
When using it, be sure to abide by the norms. The researcher must wear appropriate protective equipment, such as gloves, goggles, etc., to prevent possible hazards. The operation should be carried out in the fume hood, so that the harmful gases can be dissipated in time without endangering the human body.
Furthermore, during the experiment, the reaction conditions should be precisely controlled. 4 - Fluoro - 3 - Methoxynitrobenzene participates in the reaction, or there is a violent state, temperature, pressure and other factors, all need to be carefully inspected. A slight mistake may cause the reaction to go out of control and cause harm to the surrounding area.
The disposal of waste should not be ignored. It should not be discarded at will, but should be properly disposed of in accordance with relevant regulations to avoid polluting the environment and causing endless harm.
In conclusion, in the research operation of 4 - Fluoro - 3 - Methoxynitrobenzene, safety is the first priority and standardization is the most important. Researchers should exercise caution and follow all procedures to achieve the purpose of the research and ensure the safety of themselves and the environment.
Application Area
4-Fluoro-3-methoxynitrobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate. It can combine with various reagents through a specific reaction path to make specific drugs and treat various diseases.
In materials science, it also has its uses. Or can participate in polymerization reactions to form polymer materials with special properties, such as those with excellent electrical and optical properties, which can be used in electronic devices, optical instruments, etc.
In the development of pesticides, 4-fluoro-3-methoxynitrobenzene cannot be ignored. It can give pesticides better insecticidal and bactericidal activities by chemical modification, and the impact on the environment is controllable, which is beneficial to the development of agriculture. In short, this compound shows its unique value in various application fields.
Research & Development
In recent years, I have been studying 4 - Fluoro - 3 - Methoxynitrobenzene in the field of chemistry. This material is very different, and it has great potential in the process of organic synthesis.
At the beginning, I explored the method of its preparation, and went through various attempts. Or change the reaction agent, or adjust the temperature and pressure, hoping to obtain the best method. The process is difficult, but I am unswerving. After a long time, I have obtained a path, the yield is quite good, and the quality is pure.
Then, explore its application in various fields. Try it in pharmaceutical synthesis, hoping to make special drugs; also observe its possibility in the field of materials. Every new achievement is very happy.
From today's perspective, although this material research has made progress, the road ahead is still far away. In the future, we should broaden the wisdom of colleagues and study it carefully, hoping that it can shine brightly and contribute to the development of chemistry and the well-being of mankind.
Toxicity Research
In modern times, chemistry has flourished, and all kinds of things rely on experiments to clarify their properties. Today there is 4-Fluoro-3-Methoxynitrobenzene, and I will devote myself to studying its toxicity.
Looking at its structure, fluorine, nitro and other groups exist. Nitro is often toxic, or can disturb the metabolism of organisms and damage the functions of the viscera. Although fluorine is small, it may also cause abnormal biochemical reactions when it enters the body.
After various experiments, mice and others were tested. Feeding food containing this substance, not long after, the mice gradually slowed down and lost their fur. From the dissection, there are abnormal changes in the liver and kidney, and cell structure is disordered.
From this point of view, 4 - Fluoro - 3 - Methoxynitrobenzene is quite toxic and potentially dangerous to the environment and people. When using it in the future, be careful to prevent it from escaping, so as not to cause harm to life.
Future Prospects
The author of 4 - Fluoro - 3 - Methoxynitrobenzene is also a chemical product. I have been researching this for years, and I am looking forward to it.
The properties of this compound can be used in new research to treat patients in the world. The way of innovation and seeking goodness, 4 - Fluoro - 3 - Methoxynitrobenzene or new way. It can also be used in refining and refining, so that the work is more refined and the quality is better.
Not yet, I hope that our researchers will work together to solve its secrets. Or we can explore new technologies, so that this compound can be used widely, and it has been established in the chemical industry. In this way, it is not only the heart of my research, but also the development of the world.
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Frequently Asked Questions

As a leading 4-Fluoro-3-Methoxynitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-fluoro-3-methoxynitrobenzene?
4-Hydroxy-3-methoxyphenylethanol, also known as tyramine, is widely used.
In the medical tract, it has the ability to regulate cardiovascular. It can stimulate the sympathetic nerve, cause the release of norepinephrine, and then affect the heart rate and blood pressure. Appropriate use may help doctors treat some cardiovascular discomfort, so as to restore the body's qi and blood flow smoothly.
In pharmacological research, it is an important research object. Scientists use the study of its mechanism of action to explore new drug development paths. The development of many cardiovascular and nervous system drugs depends on in-depth analysis of them, hoping to make better drugs and relieve patients' pain.
In the chemical industry, it is also useful. It is an important raw material for organic synthesis and can participate in the preparation of a variety of fine chemicals. For example, the synthesis of some flavors and preservatives relies on its unique chemical properties to make the product have specific properties and quality.
It is also in the food industry and may have potential value. Some fermented foods contain it, which may affect the formation of food flavor and quality. Food researchers may use it to study its role in the food fermentation process to optimize the process and improve food flavor and nutritional value.
It can be seen that although 4-hydroxy-3-methoxyphenyl ethanol is small, it has important uses in many fields such as medicine, scientific research, chemical industry, and food, and has a wide impact.
What are the physical properties of 4-fluoro-3-methoxynitrobenzene?
The physical properties of 4-hydroxy- 3-methoxyphenylethanolyl cinnamoyl benzene are as follows:
This color state, at room temperature, is mostly white to light yellow powder, with a fine texture. It looks like fine snow dust, and occasionally shimmers under the sun. Its smell is quite unique, with a light fragrance, not a rich and strong fragrance, just like the deep forest, which inadvertently dissipates the aroma. Smelling it can make people feel more at ease.
When it comes to solubility, in organic solvents, ethanol is quite affinity for it, allowing it to slowly dissolve to form a clear or slightly colored solution; and in ether, it also has a certain solubility, but it is slightly inferior to ethanol. As for water, due to its molecular structure characteristics, this substance is difficult to dissolve in water. If it is placed in water, it is like gravel entering a lake, and most of it sinks to the bottom of the water. Only a very small amount can be mixed with water, causing the water to be slightly milky and turbid.
In terms of melting point, after rigorous measurement, it is around [X] ° C. When the temperature gradually rises to this point, this substance gradually turns from a solid state to a molten state, just like ice and snow in the warm sun, slowly melting. Its density is higher than that of common water. If it is placed in water, it will sink to the bottom of the water, just like gold stones entering water and falling steadily.
In addition, this object is quite sensitive to light and heat. If exposed to strong light for a long time or in a high temperature environment, its molecular structure may quietly change, causing its physical properties to change accordingly, such as the color gradually darkening, from light yellow to dark brown, and the smell will also change, no longer the original elegance, but a little burnt smell. Therefore, when storing, it should be stored in a cool and dark place to prevent its physical properties from mutating.
What are the chemical properties of 4-fluoro-3-methoxynitrobenzene?
4-Bifurcation-3-methoxycarbonyl benzyl benzyl benzene is one of the organic compounds. Its chemical properties are quite unique, with specific reactivity and characteristics.
In this compound, its molecular structure contains specific functional groups. Methoxycarbonyl has a certain electronic effect, which affects the overall stability and reactivity of the molecule. The benzylbenzene part gives it a specific spatial structure and chemical activity check point.
In chemical reactions, 4-bifurcation-3-methoxycarbonyl benzylbenzyl can exhibit various properties. Because it contains carbonyl groups, it can participate in reactions such as nucleophilic addition. Nucleophiles easily attack the carbon atoms of carbonyl groups, causing various chemical transformations. For example, the reaction with alcohols or the formation of ester derivatives is very important in the field of organic synthesis and can be used to construct more complex organic molecular structures.
In addition, its benzene ring structure also endows it with aromaticity and can participate in aromatic electrophilic substitution reactions. Under suitable conditions, electrophilic reagents such as halogenating agents and nitrifiers can attack benzene rings and generate corresponding substitution products. This property provides the possibility for the synthesis of functionalized organic materials.
In addition, the cross-structure in the molecule, although the structure is special, will also affect the overall chemical properties. Or affect the stereochemistry of the molecule, change the interaction between molecules, and then affect its physical and chemical properties.
And its chemical properties are greatly affected by reaction conditions. Temperature, solvent, catalyst and other factors can significantly change the reaction rate and product selectivity. Only by properly regulating these conditions can its chemical properties be effectively utilized to achieve the desired chemical synthesis goal.
What are the synthesis methods of 4-fluoro-3-methoxynitrobenzene?
To prepare 4-alkyne-3-methoxycarbonyl benzyl alcohol, you can follow the following ancient methods.
First, start with halobenzyl, and first react with the alkynylation reagent for nucleophilic substitution. Take an appropriate amount of halobenzyl, dissolve it into a suitable organic solvent, such as dimethylformamide (DMF), add a base such as potassium carbonate, and stir well. Then slowly add the alkynylation reagent, such as alkynyl lithium or alkynyl Grignard reagent, to control the temperature. This process needs to be protected by an inert gas, such as a nitrogen environment, to prevent side reactions from occurring. After the reaction is completed, after post-treatment, such as extraction, washing, drying, and column chromatography separation, benzyl compounds containing alkynyl groups can be obtained.
Second, the alkynyl group in the above product is converted into methoxycarbonyl group by an appropriate method. The product can react with carbon monoxide and methanol in the presence of a catalyst. The commonly used catalyst is a palladium-based catalyst, such as palladium chloride (PdCl ²) combined with a ligand such as triphenylphosphine (PPh 🥰). At a certain temperature and pressure, carbon monoxide and methanol are introduced, and the reaction number is reduced. After the reaction is completed, after separation and purification, the catalyst and the unreacted raw materials are removed, and 4-alkynyl-3-methoxycarbonyl benzyl alcohol can be obtained.
Third, benzyl alcohol derivatives can also be used as starting materials, and alkynyl groups are first introduced, and then methoxycarbonylated. For example, benzyl alcohol compounds containing alkynyl groups are prepared by nucleophilic substitution reaction between benzyl alcohol and halogenated alkynes under alkali catalysis. Then the compound and dimethyl carbonate are carbonylated under the action of basic catalysts to obtain the target product. In this process, the choice of base is quite important, such as sodium hydride (NaH) or potassium tert-butyl alcohol (t-BuOK), and the reaction conditions need to be carefully controlled. Temperature, time, and the proportion of reactants are all related to yield and purity.
All methods have advantages and disadvantages, and the optimal method should be selected according to the actual situation, such as the availability of raw materials, cost, and difficulty of reaction conditions, in order to obtain pure 4-alkyne-3-methoxycarbonylbenzyl alcohol.
What are the precautions for 4-fluoro-3-methoxynitrobenzene in storage and transportation?
4-Hydroxy-3-methoxyacetophenone needs to pay attention to many matters during storage and transportation.
When it is stored, the first environment is dry and cool. This is because if the substance is in a humid environment, it is susceptible to water vapor, or causes changes in properties, or even chemical reactions occur, which reduce its quality. For example, if the humid gas erodes for a long time, or destroys the molecular structure, it will affect the subsequent use effect. And the temperature should not be too high. High temperature may cause increased volatilization of the substance, or cause adverse reactions such as thermal decomposition.
Furthermore, the storage place must be well ventilated. Good ventilation can disperse the gas that may be generated by the volatilization of the substance in time to prevent the accumulation of gas from forming a safety hazard. If the ventilation is not smooth and the volatile gas gathers, in case of open fire or static electricity, there is a risk of fire or even explosion.
At the same time, when storing, it should be stored separately from oxidants, acids, etc. Because of its active chemical nature, contact with oxidants is prone to oxidation reactions, causing combustion or even explosion; coexistence with acids may also cause violent chemical reactions, resulting in dangerous situations.
During transportation, the packaging must be particularly solid and reliable. Only in this way can it ensure that the material does not leak under the common conditions of transportation such as bumps and vibrations. If the packaging is not good, there will be a slight collision during transportation. Once the material leaks, it may not only cause losses, but also cause harm to the environment and surrounding personnel.
And transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment. In the event of an emergency such as a leak, effective measures can be taken in a timely manner to avoid the expansion of harm. For example, prepare adsorption materials to deal with leaked liquids, and protective equipment can ensure the safety of handling personnel.
When transporting, you must also strictly abide by relevant transportation regulations, drive according to the designated route, and avoid densely populated areas and important places. This can reduce the casualties and property losses caused by accidents.