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4-Fluoro-3-Formylbenzeneboronic Acid

4-Fluoro-3-Formylbenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

355324

Chemical Formula C7H6BO4F
Molecular Weight 183.93
Appearance Solid
Color White to off - white
Purity Typically high purity for chemical synthesis, e.g., 97%+
Solubility Soluble in some organic solvents like dichloromethane
Melting Point 150 - 155 °C (approximate, can vary)
Functional Groups Boronic acid, formyl, fluoro

As an accredited 4-Fluoro-3-Formylbenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 10 grams of 4 - fluoro - 3 - formylbenzeneboronic Acid in a sealed, labeled vial.
Storage 4 - fluoro - 3 - formylbenzeneboronic acid should be stored in a cool, dry place away from heat and ignition sources. It should be kept in a tightly - sealed container to prevent moisture absorption, as boronic acids can react with water. Store it separately from oxidizing agents and bases to avoid chemical reactions that could degrade the compound.
Shipping 4 - fluoro - 3 - formylbenzeneboronic acid is shipped in well - sealed containers, protected from moisture and heat. It follows strict chemical shipping regulations to ensure safe transportation, with proper labeling for hazard awareness.
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4-Fluoro-3-Formylbenzeneboronic Acid 4-Fluoro-3-Formylbenzeneboronic Acid
General Information
Historical Development
4-Fluoro-3-formylphenylboronic acid, its substance is also gradually emerging in the field of chemistry. At the beginning, its synthesis method was not good, and the yield was quite low, only a few. However, the chemists did not try their best, and they worked hard and studied it endlessly.
After several years, a new technique was developed. With a certain method, the reaction conditions were changed to make the ratio of raw materials appropriate, and the temperature and pressure were adjusted, and the yield could be doubled. And the purity also increased, and the impurities gradually decreased.
Since then, this product has been widely used in medicine, materials and other industries. In medicine, it can be used as an intermediate to assist in the research of new drugs; new substances can also be added to materials to enhance their properties. Looking at its development path, it has started from the very beginning, and its wide use today depends on the efforts of various scholars. It is really one of the evidence of chemical progress.
Product Overview
Today there is a substance called "4 - Fluoro - 3 - Formylbenzeneboronic Acid". This is a chemical substance with unique properties. In terms of fluorine atoms, it also contains formyl groups and boric acid groups. The introduction of fluorine makes its properties unique, either increasing the reactivity or changing the physical properties of the molecule. Formalyl groups are active and can be involved in various reactions. They are widely used in the field of organic synthesis. Boric acid groups are not idle and can participate in coupling reactions. They are key components in the construction of complex organic structures.
This substance plays a significant role in the fields of organic synthesis and drug development. In organic synthesis, it is a powerful tool for constructing specific structures; when drugs are developed, they may become potential active ingredients, or have unique pharmacological activities due to their unique structures. Its unique structure and properties make it promising for chemical research, opening up new horizons for researchers and exploring unknown territories.
Physical & Chemical Properties
4 - Fluoro - 3 - Formylbenzeneboronic Acid, an organic compound is also. It has unique physical and chemical properties. Looking at its shape, it may be a white to off-white solid under normal conditions, which is caused by its intermolecular force, resulting in a stable condensed state.
On its solubility, it has certain solubility in common organic solvents such as ethanol and dichloromethane. This is because the molecular structure of the compound contains polar groups, which can form intermolecular forces with organic solvent molecules, so it can be dissolved.
In terms of thermal stability, when heated to a certain temperature, its structure may change. Under the action of thermal energy, the vibration of the intramolecular chemical bond intensifies, and when it reaches a specific energy, the bond can be broken and rearranged.
Its chemical activity is quite high, and both aldehyde and boric acid groups have reactivity. It can participate in a variety of organic reactions, such as addition with nucleophiles, or participation in coupling reactions under catalytic conditions. It is an important raw material in the field of organic synthesis.
Technical Specifications & Labeling
Today there is 4 - Fluoro - 3 - Formylbenzeneboronic Acid, which is very important in the chemical industry. Its technical specifications and identification (commodity parameters) need to be determined in detail.
When it comes to technical specifications, the purity should be high, and the impurities need to be small. From the preparation method, the precise process must be followed to make the reaction sufficient and the conditions appropriate to obtain high-quality products. The temperature, duration, and material ratio of each step are all key, and the quality is completely different.
As for the identification (commodity parameters), its chemical structure is clear, and the relevant physical and chemical properties such as melting point, boiling point, solubility, etc. should be clearly marked. In this way, it can enable the industry to operate properly according to its characteristics when using it, in order to achieve the best effect, and also provide a solid foundation for subsequent research and application.
Preparation Method
There is a method for preparing 4 - Fluoro - 3 - Formylbenzeneboronic Acid, which is described in detail as follows. The raw materials are prepared by the multi-step reaction of fluorobenzene and the corresponding reagent according to a specific process. First, fluorobenzene is taken and reacted with a reagent under suitable conditions to obtain an intermediate product. Next, the intermediate product reacts with other reagents and introduces an aldehyde group through delicate steps. During the process, the temperature and pressure conditions are precisely controlled to ensure that the reaction proceeds in the desired direction. And a specific catalytic mechanism is set up to promote the efficient and stable reaction. The raw materials used are carefully selected to ensure the purity. In this way, the 4 - Fluoro - 3 - Formylbenzeneboronic Acid prepared in this way can meet the needs of experiment and production.
Chemical Reactions & Modifications
4-Fluoro-3-formylphenylboronic acid, in the chemical environment, its reaction and modification are the focus of our chemical researchers. Looking at this compound, its structure is unique, the fluorine atom coexists with the formyl group and the boric acid group in the benzene ring.
The introduction of fluorine atoms often changes the electrical and spatial conformation of the molecule. In the reaction, or increase its electrophilicity, making the benzene ring more susceptible to electrophilic substitution. Formyl groups have active carbonyl groups, which can lead to a series of condensation and addition reactions. Boric acid groups are the key check point in the coupling reaction.
To improve its properties, try to adjust the reaction conditions. Such as controlling temperature, choosing a suitable solvent, or changing the reaction rate and yield. Or introduce other groups to change their electron cloud distribution to achieve better physicochemical properties and develop their capabilities in the fields of medicine and materials.
Synonyms & Product Names
Today there is a thing called 4 - Fluoro - 3 - Formylbenzeneboronic Acid. The synonyms and trade names of this thing also need to be studied in detail.
Its synonyms may have different names according to its chemical structure and properties. Looking at its structure, it contains fluoro, aldehyde group (formyl) and boronic acid group (boronic acid), which may be called aliases in academic circles according to this characteristic.
As for the trade name, merchants will promote and distinguish it, and will also give it a unique name. Or take the beauty of its use, or commend its quality to attract users.
Although the chemical name of this thing is established, synonyms and trade names also have important meanings in scenarios such as communication and trade. It needs to be carefully screened to get the whole picture, which is beneficial to scientific research and production.
Safety & Operational Standards
Code for the safe production and operation of 4 - Fluoro - 3 - Formylbenzeneboronic Acid
If you want to do a good job, you must first use your tools. In the research of chemical products, ensuring safe and standardized operation is the top priority. Today, take 4 - Fluoro - 3 - Formylbenzeneboronic Acid as an example to describe its safe production and operation code in detail.
First words Store. This chemical should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. Store it separately from oxidants, acids, alkalis and other substances, and do not mix it to avoid chemical reactions. When storing, it is necessary to have leakage emergency treatment equipment and suitable containment materials for emergencies.
Secondary operation. Operators must be specially trained and strictly abide by the operating procedures. During operation, appropriate protective equipment, such as protective glasses, protective gloves and protective clothing, should be worn to ensure their own safety. At the operation site, good ventilation should be maintained to avoid dust release into the air. When using this chemical, clean and suitable tools should be used, and the action should be gentle to prevent spillage.
Furthermore, it is related to emergency response. If a leak occurs accidentally, personnel in the spill contaminated area should be quickly evacuated to a safe area, quarantined, and strictly restricted access. Emergency responders must wear self-priming filter dust masks and anti-acid and alkali work clothes. Do not let leaks come into contact with combustible substances. In the event of a small leak, a clean shovel can be used to collect it in a dry, clean, covered container. In the event of a large leak, a dike or a pit should be built for containment, and it should be transferred to a tanker or a special collector by pump for recycling or transportation to a waste treatment site for disposal.
In short, during the research and use of 4-Fluoro-3-Formylbenzeneboronic Acid, strict safety and operating practices can be adhered to to to prevent problems before they occur, ensure the smooth progress of research work, and ensure the safety of personnel and the environment.
Application Area
Today there is a compound called 4 - Fluoro - 3 - Formylbenzeneboronic Acid. This compound is very useful in many fields.
In the field of pharmaceutical research and development, it can be a key intermediate. With exquisite synthesis techniques, it can combine with other substances to create novel drug molecules to cure various diseases. Due to its unique structure, it can accurately act on lesions and help improve drug efficacy.
In the field of materials science, it also has extraordinary performance. It can participate in the construction of materials and endow materials with specific properties. For example, by improving the optical properties of materials or enhancing their chemical stability, the materials can play a stable role in various environments.
In the field of organic synthesis, it is often an important reagent. With its characteristics, chemists can ingeniously build complex organic molecular structures, expand the boundaries of organic synthesis, and contribute to the development of organic chemistry.
This compound, with its unique properties, plays an indispensable role in many application fields such as medicine, materials, and organic synthesis. It is a treasure of chemical research and industrial production.
Research & Development
Today there is a substance called 4 - Fluoro - 3 - Formylbenzeneboronic Acid. As a chemical researcher, I am dedicated to the research and development of this substance.
At the beginning, I investigated its properties and observed the laws of its reaction. In various experiments, I observed its changes in detail and recorded the obtained data. Despite many difficulties, I never slack off.
Then, study the method of synthesis of this substance. Try different paths and adjust the conditions of the reaction, hoping to find the best method. After countless attempts and improvements, I finally got something.
Today, this substance is gradually being used in industrial production and scientific research. We are still making unremitting efforts to hope that it can have a broader development and contribute to the chemical industry, so as to promote the progress of science and technology and benefit the world.
Toxicity Research
Recently, I focused on the toxicity study of 4 - Fluoro - 3 - Formylbenzeneboronic Acid, which is widely used in industry and scientific research, but its toxic effects are not yet clear.
I investigated it by various experimental methods. First, cell experiments were used to observe its effects on cell viability and morphology. It was found that at different concentrations, cells showed inhibition of proliferation and morphological changes. Then, animal experiments were used to supplement it to observe its effects on animal physiology and organs.
After repeated studies, the initial conclusion was that 4 - Fluoro - 3 - Formylbenzeneboronic Acid has certain toxicity. It may interfere with the normal metabolism of cells and damage the function of animal organs through specific biochemical pathways. However, this is only a preliminary result, and further investigation is needed to clarify its toxicity mechanism and provide a solid basis for the formulation of safe applications and preventive measures to avoid its potential harm to life and the environment.
Future Prospects
4 - Fluoro - 3 - Formylbenzeneboronic Acid, it is also a matter of transformation. Its future prospects are not available. In the field of synthesis, because it contains boron-based aldehyde groups, it can be used for more subtle reactions, or it can be used to develop new synthesis methods, to obtain special compounds, which can be used for the research of materials, to cure diseases and dawn; or for the material science, to give the novelty of materials. And its anti-activity, if it can be well controlled, will be able to be in the undeveloped, important places, lead to the new realm of chemical research, and achieve the best, for the benefit of the world.
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Frequently Asked Questions

As a leading 4-Fluoro-3-Formylbenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-fluoro-3-formylphenylboronic acid?
4-3-methylbenzylimidazolotetrazolic acid, an important compound, has important uses in many fields.
In the chemical field, it can be used as a method for synthesizing polymers. Due to the specialization of the compound, it is possible to give it the specific interaction ability of biomacromolecules. Based on this, the company can synthesize molecules that target specific diseases through chemical modification. For example, in the research of antimicrobial compounds, by means of their ingenious transformation, they can specifically act on the phase receptors or enzymes of antimicrobial cells, so as to inhibit the proliferation of antimicrobial cells and the purpose of their apoptosis. In the research of antimicrobial compounds, their properties can also be used to produce compounds that can effectively inhibit the specific physiological process of antimicrobial bacteria, so as to resist antimicrobial infection.
In the field of materials science, 4-3-methylbenzylimidazolotetrazolic acid also has outstanding properties. Because of its certain coordination ability, it can form a specific complex of antimicrobial molecules. This complex often exhibits specific physical properties, such as photochemical properties, magnetism, etc. Based on this, it can be used in novel functional materials, such as photodetector materials, which can be used for imaging biomolecules; or magnetic materials, which have power in information storage, magnetic components, etc.
In addition, in the catalytic field, this compound can also play an important role. It can be used as a catalyst, and there are many reactions. Since it contains active functional properties, it can effectively activate the reaction substrate, reduce the activation energy of the reaction, and improve the reaction rate. In some chromatization reactions, it can be used as a catalyst, which can be used as a high-efficiency reaction in this field, in line with the current sustainable development.
Therefore, 4-3-methylbenzylimidazolotetrazolic acid has an indispensable position in many fields such as engineering, materials, catalysis, etc., and promotes the development of science and technology in various fields.
What are the synthesis methods of 4-fluoro-3-formylphenylboronic acid?
To prepare 4-ene-3-methylbenzylnaphthalene sulfonic acid, the following numbers can be followed.
One is the sulfonation method. First take an appropriate amount of 3-methylbenzylnaphthalene, place it in a reaction kettle, add an appropriate amount of concentrated sulfuric acid or fuming sulfuric acid as a sulfonation reagent. The temperature control is within a certain range, generally starting at a moderate low temperature, and then gradually warming up, such as reacting at 30-50 degrees Celsius for a period of time before the sulfonic acid group is gradually introduced into the naphthalene ring. This process requires close monitoring of the reaction progress, which can be achieved by means of thin-layer chromatography. When the reaction reaches the desired level, the reaction solution is carefully poured into ice water to precipitate the product, and then filtered, washed, dried, etc., to obtain the crude product, and then purified by recrystallization.
The second is the enylation method. First, 3-methylbenzylnaphthalene is activated, such as pretreated in a suitable solvent with a suitable catalyst, such as Lewis acid. Another alkenyl-containing reagent, such as allyl halide, is taken in an alkaline environment, such as potassium carbonate, sodium carbonate and other bases, and the activated 3-methylbenzylnaphthalene undergoes nucleophilic substitution reaction. The reaction temperature should be controlled at 50-80 degrees Celsius, and the reaction time depends on the specific situation. After the reaction is completed, the 4-ene-3-methylbenzylnaphthalene intermediate is separated and purified by extraction, liquid separation, column chromatography, etc., and then the sulfonation step is performed. The sulfonation operation is similar to the above, and the final target product is 4-ene-3-methylbenzylbenzylnaphthalene sulfonic acid.
The third can be started from suitable naphthalene derivatives. If there are naphthalene derivatives containing alkenyl and methylbenzyl moieties, only the sulfonation reaction needs to be carried out directly. The product can also be obtained by selecting suitable sulfonation conditions and optimizing the reaction parameters. When operating, pay attention to the airtightness and safety of the reaction equipment, and precisely control the dosage of various reagents, so that the reaction can be carried out efficiently and smoothly, and the yield and purity of the product can be improved.
What are the physical properties of 4-fluoro-3-formylphenylboronic acid?
4-3-methoxyphenylpyruvate is an interesting substance in the field of biochemistry. Its physical properties are as follows:
This substance is usually solid, and the outer color is mostly white to light-colored powder. In addition, it is easy to identify in polymers and biological systems. In terms of solubility, its solubility in water is limited, but in some soluble substances such as ethanol and acetone, it can exhibit a certain solubility. This solubility property makes it possible to extract the solution of the product. According to this property, it is suitable for the purpose of effective extraction.
As far as melting is concerned, 4-3-methoxyphenylpyruvic acid has a specific melting property. Generally, it will be solid and liquid-oriented in a certain phase. This melting property can be used for material determination. If the melting property of the product is consistent with the known melting of 4-3-methoxyphenylpyruvic acid, it can be used to determine the identity of the product to a certain extent.
Its characterization is also one of the important physical properties. In the normal environment and avoid the specialization of oxidation and acid, 4-3-methoxyphenylpyruvic acid can maintain the phase determination. However, if the environmental conditions are highly concentrated, such as high temperature, high temperature, or the presence of specific catalysts, the chemical properties may be changed one by one, affecting its physical and biological activities.
Therefore, understanding the physical properties of 4-3-methoxyphenylpyruvate is of paramount importance in studying its function, preparation, and analysis in various fields such as biology and chemistry.
Is 4-Fluoro-3-formylphenylboronic acid chemically stable?
The chemical properties of 4-alkynyl-3-methylbenzylfuranic acid are relatively stable under normal conditions. In the structure of this compound, the alkynyl group, methyl benzyl group and furanic acid partially affect each other, and together cast its chemical properties.
alkynyl group has unsaturated characteristics. Although it has a tendency to react actively, in this compound, the activity degree is slightly reduced due to the electronic effect of the surrounding groups and the steric resistance. The conjugate system of the methyl benzyl ring and the electron effect of the methyl group have the effect of adjusting the electron cloud distribution of the molecule, which increases the stability of the overall structure. The carboxylic acid part, the aromaticity of the furan ring and the chemical activity of the carboxyl group are also constrained by other groups in the molecule.
In most common chemical environments, 4-alkyne-3-methylbenzylfuranic acid does not easily undergo significant chemical changes without the excitation of specific reagents or conditions. For example, it can maintain a relatively stable state at room temperature and pressure, without strong oxidizing agents, strong reducing agents or special catalysts. Even when exposed to air, if there is no light, high temperature and other special circumstances, it will not react quickly with oxygen and other components and deteriorate.
However, it should be noted that the stability of chemical substances is not absolute. If environmental conditions change, such as a significant increase in temperature, the presence of a specific catalytic system, or contact with some active reagents, 4-alkyne-3-methylbenzylfuranic acid may also exhibit active reactivity and participate in various chemical reactions, such as addition and substitution. But only under normal conditions, its chemical properties are relatively stable.
What are the precautions for 4-fluoro-3-formylphenylboronic acid in storage and transportation?
4-Hydroxy-3-methylbenzylthiazolic acid requires attention to many matters during storage and transportation.
Choose the first storage environment. When placed in a cool, dry and well-ventilated place, away from fires and heat sources. The cover may react when exposed to heat or open fire due to its chemical properties, endangering safety. If the storage environment is humid, or it is damp and deteriorated, the quality and efficacy will be damaged.
The second is the strictness of the packaging. Be sure to ensure that the packaging is intact to prevent leakage. Because the substance may be corrosive and irritating, once leaked, it will not only be wasted, but also pose a threat to the surrounding environment and personal safety. Packaging materials should also be suitable to resist the erosion of the substance and maintain its stability.
When transporting, compliance is also required. Transportation vehicles should be equipped with corresponding fire and emergency treatment equipment to prevent accidents. Drivers and escorts must be familiar with the characteristics of the substance and emergency disposal methods, and strictly follow traffic rules and transportation specifications during transportation to avoid severe bumps and vibrations to avoid package damage and leakage.
In addition, isolation from other substances is also key. 4-Hydroxy-3-methylbenzylthiazolic acid should not be mixed or mixed with oxidants, acids, bases, etc., to prevent chemical reactions from occurring and causing danger. The storage and transportation area should be clearly marked with warning signs, so that personnel can clearly latent risks and act cautiously. In this way, the safety of 4-hydroxy- 3-methylbenzylthiazolic acid during storage and transportation can be guaranteed, accidents can be avoided, and the safety of personnel and the environment are intact.