4-Fluoro-2-Methylbenzenesulfonyl Chloride

Hongda Chemical

Specifications

HS Code	770233
Chemical Formula	C7H6ClFO2S
Molecular Weight	210.64
Appearance	Typically a colorless to light - yellow liquid
Boiling Point	Specific value may vary, around 250 - 260°C under normal pressure
Density	Specific density value around 1.4 - 1.5 g/cm³
Solubility	Soluble in many organic solvents like dichloromethane, chloroform
Vapor Pressure	Low vapor pressure at room temperature
Stability	Reactive, sensitive to moisture and water, can hydrolyze
Odor	Pungent, characteristic sulfonyl chloride odor

As an accredited 4-Fluoro-2-Methylbenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - fluoro - 2 - methylbenzenesulfonyl chloride in a sealed, corrosion - resistant bottle.
Storage	4 - fluoro - 2 - methylbenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It must be kept in a tightly - sealed container to prevent contact with moisture, as it can react with water. Store it separately from incompatible substances like bases, amines, and reducing agents to avoid dangerous reactions.
Shipping	4 - fluoro - 2 - methylbenzenesulfonyl chloride is a chemical that requires careful shipping. It should be packaged in sealed, corrosion - resistant containers, transported in accordance with hazardous chemical regulations, ensuring safety during transit.

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4-Fluoro-2-Methylbenzenesulfonyl Chloride

General Information

Historical Development

In the field of chemical industry, new products are emerging one after another. 4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride also has its own unique development process. At the beginning, everyone explored the path of chemical research and studied various compounds carefully. As the years passed, researchers tried unremitting and went through countless experiments. Either because of the delicate control of reaction conditions, or because of the continuous adjustment of the ratio of raw materials, the method of synthesis of this product was gradually clarified. From the initial ignorance and temptation to the gradual maturity of the process, it is like a long road, leaving the mark of exploration step by step. From the hardships of the past, it has finally made this product emerge in the chemical industry today, laying the foundation for many subsequent research and applications.

Product Overview

4-Fluoro-2-methylbenzenesulfonyl chloride is an important reagent for organic synthesis. Its color is colorless to slightly yellow liquid with a pungent smell. This compound has a wide range of uses in the field of organic synthesis and is often the key raw material for the preparation of sulfonamides, sulfonates and other compounds.
The preparation method is often obtained by reacting 4-fluoro-2-methylbenzenesulfonate with chlorination reagents. The reaction process requires fine control of conditions, such as temperature, reactant ratio, etc., to ensure the purity and yield of the product.
When storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent danger. When using it, it is also necessary to follow strict operating procedures and take protective measures to avoid harm to the human body. In short, 4-fluoro-2-methylbenzenesulfonyl chloride plays an important role in the development of organic synthesis and contributes greatly to the progress of related fields.

Physical & Chemical Properties

4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride, an organic compound. Its physical and chemical properties are quite specific. Looking at its shape, at room temperature, it is mostly a colorless to slightly yellow liquid with a pungent smell, which is one of its physical characteristics. In terms of its chemical properties, its sulfonyl chloride group is extremely active and easily reacts with various compounds such as alcohols and amines to form esters and amides. This reactivity is derived from the electron cloud distribution of sulfur atoms in sulfonyl chloride, making it vulnerable to attack by nucleophiles. It has a wide range of uses in the field of organic synthesis and is often a key raw material for the preparation of special functional materials and pharmaceutical intermediates. Due to its liveliness, when storing and using, it is necessary to be cautious and avoid contact with water and highly active substances to prevent the occurrence of adverse reactions and ensure the safety of experimentation and production.

Technical Specifications & Labeling

There is a product today, named 4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride. To clarify its technical specifications and labels (commodity parameters), it should be carefully examined.
To see its quality, it must be pure and free of impurities, with a positive color and an absolute odor. The proportion of ingredients it contains must be accurate, and it must not be different at all. For example, the ratio of fluorine, methyl and other elements is fixed.
In terms of its shape, whether it is crystalline or liquid, it should be uniform, without agglomeration or precipitation.
In terms of identification, on the packaging, the name must be stated, the chemical formula must be noted, and various parameters, such as molecular weight, melting point, boiling point, etc., must be listed in detail, so that the viewer can see at a glance, without suspicion. And the logo must be clear and recognizable, and it must not be corroded for a long time to ensure that its information is accurate. In this way, it is necessary to meet the technical specifications and labels (commodity parameters) of this product.

Preparation Method

4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride is an important organic compound. The preparation method and the selection of raw materials are the key. Benzene compounds containing fluorine and methyl can be selected as starting materials. In the preparation process, the raw materials are first subjected to a sulfonation reaction, and the sulfonic acid group is introduced. This step needs to be carried out at a suitable temperature and under the action of a catalyst to ensure the efficient advancement of the reaction. Then, the sulfonic acid product is converted into sulfonyl chloride, usually using chlorinating agents such as phosphorus pentachloride. The reaction steps are rigorous, and each step needs to precisely control the reaction conditions, such as temperature, reaction time and the proportion of reactants.
In this process, the activation mechanism is also extremely important. The reactant molecules are activated under specific conditions to enhance the reactivity. For example, by heating up and adding catalysts, the molecular activity is enhanced to achieve the purpose of efficiently preparing 4-Fluoro-2-Methylbenzenesulfonyl Chloride, ensuring the quality and yield of the product.

Chemical Reactions & Modifications

Today there is a substance called 4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride. In the field of chemistry, its reaction and modification are particularly critical.
Looking at its reaction, this compound often undergoes chemical changes when it encounters other substances. Or when it encounters a nucleophilic reagent, the nucleophilic group attacks its sulfonyl chloride site, causing chlorine to leave and form a new compound. This change is also due to the activity of sulfonyl chloride, its bond is easy to break, making the reaction easy.
When it comes to modification, its properties can be adjusted by various methods. Or on the benzene ring, add other groups, change its electron cloud distribution, and change its chemical activity. Variable reaction conditions, such as temperature and solvents, can also guide the reaction direction to obtain different products. In this way, heterogeneous and functional substances can be obtained, which are useful in the fields of medicine and materials. After exquisite reaction and modification, the potential of this compound can be developed, which adds to the progress of chemistry.

Synonyms & Product Names

4-Fluoro-2-methylbenzenesulfonyl chloride is a chemical raw material. Although its name is different, it refers to one. It is called fluorotoluenesulfonyl chloride, and it is also called by its characteristics. This substance has a wide range of uses and is often a key raw material in various chemical synthesis. It can participate in a variety of reactions to produce other compounds. Between businesses, or because of its convenient name, it has another name. However, no matter what the name is, its quality remains unchanged and its properties are the same. They are all important substances in chemical synthesis and can lead to exquisite products. The industry is in the city, and they are often known by different names, but everyone in the industry knows that they are all called this 4-fluoro-2-methylbenzenesulfonyl chloride. Although the name is different, it is actually the same.

Safety & Operational Standards

4-Fluoro-2-methylbenzenesulfonyl chloride is an important substance in chemical research. If you want to use it properly, you must clarify its safety and operation specifications.
This substance is dangerous. It is irritating to the skin, eyes and respiratory tract. Therefore, when operating, protective gear is indispensable. The operator should wear protective clothing, such as ordinary cotton clothing, to prevent it from staining the skin. And must wear protective gloves, such as rubber gloves, to ensure that the hands are not damaged. Protective glasses are also essential to protect the eyes from its harm.
The operating environment should also be paid attention to. It should be done in a well-ventilated place, if in a fume hood. This can allow volatile gases to be quickly discharged, so as not to accumulate indoors and endanger people. The operation process must be rigorous. When taking it, use a suitable appliance, and the action should be slow, so as not to splash out. Weighing is accurate, according to the amount required for the experiment, not more or less.
After use, properly dispose of the remaining things. Do not dump at will to prevent pollution of the environment. Storage is also particular. It should be placed in a cool, dry place, and sealed to avoid mixing with other substances to avoid chemical reactions.
In short, in the research operation of 4-fluoro-2-methylbenzenesulfonyl chloride, always keep in mind the safety first, and strictly abide by the operating specifications, so as to achieve the purpose of the research and ensure the safety of people and the environment.

Application Area

4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride is also a chemical substance. Its application field is quite extensive. In the field of pharmaceutical synthesis, it is often a key raw material. It can help doctors make special drugs, treat various diseases, and save patients from suffering. In material science, it is also wonderfully useful. By participating in reactions, it can make materials unique, such as enhancing their toughness and corrosion resistance. In organic synthetic chemistry, it is a powerful tool. Chemists can create complex and delicate molecular structures and expand the new realm of chemical research. From this point of view, 4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride has an indispensable position in many fields, and has made outstanding contributions to promoting scientific progress and improving people's well-being.

Research & Development

In recent years, Yu has dedicated himself to the research of 4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride. This compound has unique properties and has considerable application potential in various fields.
At the beginning, I studied its synthesis method, enumerated trial and error, and obtained a better way. With a certain raw material, after specific reaction steps, controlled by precise conditions, it can gradually increase its yield and improve its purity.
Then, explore its properties. In terms of chemical properties, it shows a unique state in response to various reagents, which can inspire new reaction mechanisms. Physical properties are also investigated in detail, such as melting point, solubility, etc., which are the foundation for subsequent applications.
At present, although some progress has been made, the road ahead is still far away. To expand its application, it will be widely explored in the fields of medicine and materials, hoping to develop its greater value, and to promote the research and application of this compound to reach a new realm.

Toxicity Research

Toxicity of 4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride. This substance is chemically active, and its toxicity is related to user safety and environmental impact. I studied it with ancient methods to observe its response to various substances.
Take the number of mice, divide them into groups, and administer different amounts of this compound. Not long after, I saw that those who received large doses, their movements slowed down, their diet was wasted, and their bodies showed signs of discomfort. After dissection, I saw that there was damage to the organs, especially the liver and kidneys.
This substance was placed in water and soil to observe the changes of microorganisms and plants. The number of microorganisms in the water decreased, the activity decreased; plants in the soil, growth was inhibited, and leaf color was abnormal.
From this point of view, 4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride is toxic and potentially dangerous to humans, organisms and the environment. The research results should be used as evidence for protection and treatment to prevent its harm from flowing into the world.

Future Prospects

4 - Fluoro - 2 - Methylbenzenesulfonyl Chloride, it is also a chemical thing. It can be looked forward to in the future. With its unique properties, it can be used in many fields or has extraordinary applications.
In the field of materials, it may be able to assist in the research of new functional materials, and its special properties can make the materials have unique physical and chemical properties, which can be used in high-end scientific and technological products. In the field of technology, or an important starting material for new research, it can be skillfully repaired, or it can obtain special effects and solve the difficulties of many diseases.
In addition, the step of technology, the synthesis method or more refined, the cost is reduced and the amount is increased, making this compound more widely used in all walks of life. In the future, it will be able to improve its characteristics, expand its color in chemical industry, scientific research, etc., and promote the development of many fields. The prospect is promising.

Where to Buy 4-Fluoro-2-Methylbenzenesulfonyl Chloride in China?

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Frequently Asked Questions

As a leading 4-Fluoro-2-Methylbenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Fluoro-2-Methylbenzenesulfonyl Chloride?

4-Fluoro-2-methylbenzenesulfonyl chloride has a wide range of uses. In the field of organic synthesis, it is often a key reagent.
First, it can be used to prepare sulfonamide compounds. In the synthesis of many drugs, the structure of sulfonamides is crucial. The reaction of 4-fluoro-2-methylbenzenesulfonyl chloride with amines can successfully generate sulfonamides through specific reaction conditions. Such sulfonamide compounds have unique biological activities or are important intermediates for the development of new drugs, which are of great significance in the field of medicinal chemistry.
Second, it also has applications in the field of materials science. Its participation in the reaction can build polymers containing special functional groups. For example, by reacting with polymer monomers containing hydroxyl or amino groups, the polymer can be modified. The modified polymer may have better solubility, thermal stability, or improved surface properties, such as improved hydrophilicity or hydrophobicity, so as to meet the needs of different material application scenarios.
Furthermore, in the synthesis of dyes, 4-fluoro-2-methylbenzenesulfonyl chloride can introduce specific functional groups to optimize the structure of the dye. Make the dye have better dyeing properties, such as improving its affinity for fibrous materials, improving dyeing fastness, etc. Therefore, it plays an indispensable role in the textile printing and dyeing industry.
In summary, 4-fluoro-2-methylbenzenesulfonyl chloride, with its unique chemical activity, is an indispensable and important substance in many fields such as organic synthesis, materials science and dye synthesis, promoting the development and innovation of various fields of technology.

What are the physical properties of 4-Fluoro-2-Methylbenzenesulfonyl Chloride?

4-Fluoro-2-methylbenzenesulfonyl chloride is a very important chemical raw material in organic synthesis. Its physical properties are unique, let me tell them one by one.
Looking at its properties, under room temperature and pressure, 4-fluoro-2-methylbenzenesulfonyl chloride often takes the form of a colorless to pale yellow liquid, just like a clear but mysterious liquid. Under the sun, it can be seen that it has a slight flickering luster, as if it contains unique energy.
When it comes to odor, this substance emits a pungent odor, which is sharp and unique. Even if it exists only in a small amount in the air, it can also sensitively stimulate people's olfactory nerves, making people instantly aware of its existence, like a sharp arrow, reaching the senses.
Its boiling point is also one of the key physical properties. Generally speaking, the boiling point is in a specific temperature range. Under specific pressure conditions, when the temperature rises to the corresponding value, the substance will be converted from liquid to gaseous. The characteristics of this boiling point are of great significance in chemical production for its separation, purification and other operations, just like drawing a precise roadmap for the production process.
As for the melting point, although it is slightly less concerned than the boiling point, it cannot be ignored. The value of the melting point determines the conditions required for the substance to change from solid to liquid. During storage and transportation, the characteristics of the melting point affect the form of its existence, like a barrier that restricts its state under different temperature environments.
In addition, the density of 4-fluoro-2-methylbenzenesulfonyl chloride also has its own characteristics. This density determines its distribution when mixed with other substances. In a chemical reaction system, the difference in density may affect the process and result of the reaction, just as it controls the rhythm of interactions between substances in the microscopic world. In terms of solubility, it is soluble in some organic solvents, providing a broad application space for it in organic synthesis reactions. It can cooperate with many organic solvents to set the stage for various complex organic synthesis reactions. Like a skilled dancer, it can fully display its chemical charm on the right stage.

What are the synthesis methods of 4-Fluoro-2-Methylbenzenesulfonyl Chloride?

The synthesis of 4-fluoro-2-methylbenzene sulfonyl chloride has followed several paths in the past. One method is also to use 4-fluoro-2-methylbenzene as the starting material and introduce the sulfonic acid group through the sulfonation step. In this process, concentrated sulfuric acid or fuming sulfuric acid are often used as the sulfonation reagent. Concentrated sulfuric acid has strong acidic and sulfonation activity. At a suitable temperature and reaction time, it can undergo electrophilic substitution reaction with the benzene ring, so that the sulfonic acid group is connected to the benzene ring to obtain 4-fluoro-2-methylbenzene sulfonic acid.
Next, the obtained 4-fluoro-2-methylbenzenesulfonic acid is converted into 4-fluoro-2-methylbenzenesulfonyl chloride. This step is usually achieved by chlorination reagents, such as phosphorus pentachloride (PCl) and thionyl chloride (SOCl ²). Taking thionyl chloride as an example, when it reacts with 4-fluoro-2-methylbenzenesulfonic acid, the hydroxyl group of the sulfonic acid group is replaced by chlorine atoms to form the target product 4-fluoro-2-methylbenzenesulfonyl chloride, and the thionyl chloride itself is converted into sulfur dioxide and hydrogen chloride gas to escape. This reaction condition is relatively mild, and the product is easy to separate and purify.
There are other ways, or from other related aromatic derivatives, through multi-step reactions, the structure of the target molecule is gradually constructed. However, these methods may require more complex reaction flow and condition control, and require high reaction equipment and operation skills. There are also factors such as raw material cost, reaction yield, and the number of side reactions, and the optimization and improvement of the synthesis route are aimed at finding an efficient, economical and environmentally friendly method for synthesizing 4-fluoro-2-methylbenzenesulfonyl chloride.

What to look out for when storing and transporting 4-Fluoro-2-Methylbenzenesulfonyl Chloride

4-Fluoro-2-methylbenzenesulfonyl chloride is a commonly used reagent in organic synthesis. When storing and transporting, many matters need to be paid careful attention.
Storage first. This compound is corrosive and reactive, and should be stored in a cool, dry and well-ventilated place. Excessive temperature can easily cause it to decompose or cause dangerous reactions, so it must be kept away from heat and ignition sources. Because it is sensitive to moisture and easily hydrolyzed, it should be ensured that the storage environment is dry, it can be placed in a sealed container, and the container material should be selected to resist its corrosion, such as glass or specific plastic materials. At the same time, it is necessary to avoid contact with alkaline substances, alcohols, amines and other substances that are easy to react with to prevent uncontrollable chemical reactions.
As for transportation, the first heavy packaging is tight. Be sure to use packaging materials that meet relevant safety standards to ensure that there is no risk of leakage during transportation. Transportation vehicles also need to be equipped with corresponding emergency treatment equipment to prevent timely response in case of leakage. Transportation personnel should be familiar with the dangerous characteristics of this compound and emergency treatment methods, and the transportation process should strictly follow relevant laws and safety regulations. When loading and unloading, the operation should be gentle to avoid collision and friction to prevent package damage.
In short, whether it is storing or transporting 4-fluoro-2-methylbenzenesulfonyl chloride, it is necessary to have a full understanding of its characteristics, strictly abide by safety regulations, and operate with caution to ensure that personnel safety and the environment are not endangered.

What is the market price range for 4-Fluoro-2-Methylbenzenesulfonyl Chloride?

I am looking at your question, and I am inquiring about the market price range of 4-fluoro-2-methylbenzenesulfonyl chloride. However, the price of this chemical often changes for various reasons, and it is difficult to determine the number.
The change in its price is primarily related to the price of raw materials. The production of 4-fluoro-2-methylbenzenesulfonyl chloride depends on the relevant raw materials. If the price of raw materials rises and falls, the price of finished products will also follow. For example, if the supply of raw materials is short, the price will rise, causing the price of 4-fluoro-2-methylbenzenesulfonyl chloride to also rise.
Furthermore, the complexity and cost of the production process also affect the price. If the process is complicated, high-end equipment and exquisite technology are required, the cost will be high, and the price will be expensive. And the cost of energy consumption, manpower and other costs in the production process all affect the final price.
The situation of market supply and demand is even more critical. If the market has strong demand for this product, but the supply is limited, the price will rise; on the contrary, if the supply is abundant and the demand is insufficient, the price will fall.
In addition, differences in regions and manufacturers also make prices different. In different places, prices vary due to factors such as transportation costs and market competition. Manufacturers also have different pricing due to their own cost control, brand influence, etc.
In summary, the market price range of 4-fluoro-2-methylbenzenesulfonyl chloride is in dynamic changes due to various factors such as raw materials, processes, supply and demand, regions and manufacturers, etc. It is difficult to determine the exact range. It is necessary to consider the general situation at a specific time and place to know the approximate price.